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The map label for this gene is 113475994

Identifier: 113475994

GI number: 113475994

Start: 3647884

End: 3649884

Strand: Direct

Name: 113475994

Synonym: Tery_2362

Alternate gene names: NA

Gene position: 3647884-3649884 (Clockwise)

Preceding gene: 113475993

Following gene: 113475997

Centisome position: 47.07

GC content: 44.33

Gene sequence:

>2001_bases
ATGCCCGAAATTTCTTCAATTCCTGGAATCAAACAACTATGGGCAAAAACCAAAGGTAACTCTGAGGTTTGCGTGGCAGT
GCTTGACGGTCTAGTTGACCTGAAACATCCTTGTTTTGAGGGAGCTAATTTGACTCAACTACCAAGCTTAGTTCAAGGTC
AAGCTACTCCTCAAAGCGAGATGTCTCTCCATGGGACTCATGTGGCCAGTATAATTTTTGGTCAGCCAAACTCAAGCGTC
TCTGGTATTGCTCCCCACTGTCGAGGTTTAATAGTTCCCATATTCTCAGACTATCATCGCCGAACTTCTCAGTTGAATTT
AGCACGGGCCATCGAACAAGCGGTGAATGCTGGGGCTAATATTATTAATATTAGTGGGGGTGAACTGACAGATTATGGTG
AAGCTGAAGACTGGCTTAACCGTGCGGTGAGTTTATGCCAAAATAATAATGTTTTGCTTGTTGCTGCAGCGGGTAATGAC
GGCTGTGAATGTTTGCATGTTCCGGCAGCACTACCCACTGTTCTAGCAGCAGGAGCCATGGGAGAAAACGGACAGCCCCT
AGATTATAGTAACTGGGGCGAAAATTATCAGACTCAAGGTATTCTGGCTCTGGGAGAAAATATTTTAGGTGCTGAACCAG
GAGGTGGTACAAGACAGTTGAGTGGGACCAGCTTTGCCACCCCAGTAGTGTCAGGAGTTGCTGCATTATTGATGAGTTTG
CAGTTGCAAAGAGAGGAAAAACCAGACTCACAAAAAGTGCGTACTGCCTTACTCAAGACAGCTGTTCCATGTCATGCTCA
AGAAAAACGCCGTTGTTTAGTTGGCCAGATGAATATTTCAGGTGCCATTGCACATATAACAGGAGAAACTATGTCAGAAT
CAGAACAAGATAATAGTAATGGTATTGAAGCTAGCTGTGGTTGTGAGTCAACTCCAGAAGCTAGCTTGCCAGGTTCAGTT
GGCCTAGAAAATAGTCTACCGACTCCCGCCGACAATGGTGTGGTAGCTGCAGGGGTCGTTGAAGCTGGCGTCACGGCTTC
ACAACCATTATCATCAACTAATACATCTAATACATCTAATAATCAAATTTCTGCTATGCCAAATAATAGTCAAAGTAACA
ATAGTAATGGAATCACACCCAGTCAACCTCCTCAAGACGTGACAAATATAGTCTACGTTATTGGTACATTGGGTTATGAC
TTTGGAACTGAAGCACGGCGGGACTCATTTAAACAGTTGATGCCAGCAGTTACTATTGGAAATACCCAAATTCCAGCTAA
CCCTTATGATGCTCGTCAAATGGTGGATTATTTGGCGAATAATCTTTCGGAAGCTAAATCTTTGATTTGGACTTTGAATA
TGGAATTGACTCCTATCTATGCTATTGAAGCTGTGGGGTCATTTGCACGGGAAGTTTATGAAGCTTTGCAAGAGTTACTT
GCAGGGGAAGTAGAAGCGGAAGATGCTGAGAGATATATTGAGCGGGTGAGTATTCCGGGAAAATTAACTGGGCGTACAGT
TAAGTTGTTCTCAGGCCAAGTGGTGCCTGTGATTGAACCTGTTAGTCCTCGTGGTATTTATGGCTGGCGGGTGAATACAT
TGGTTGGTTCTGCTTTGGAAGCAGTTCGTGGAGAACAAGCAGAGGCTGACGATGAGCAAATGCGTCGGAGTTTGAGCAGT
TTCCTAAATCGAGTTTATTACGATCTACGCAATTTAGGGCAGACTTCTCAAGACCGAGCTTTAAATTTTGCAGCTACTAA
TGCTTTCCAAGCGGCTCAAACTTTCTCTACAGCAGTGGCAGCAGGCATGGAGTTGGATAGTATTGCTGTGACCAAGAGTC
CATTCTGTCGGATGGATAGTGATTGTTGGGACGTGCAGTTGAAGTTTTTCGATCCAGAAAATAACCGTCGGGCGAAGAAG
GTGTTCCGGTTTACCATTGATGTTAGCGATTTCATTCCGGTAACTTTGGGCGAAGTTCGTTCTTGGTCTTCTCCTTATTA
G

Upstream 100 bases:

>100_bases
TTACTATGGTAAGTTATATACGATTTATAAAAAAACAGGAGTTAAACATTGGTAACTAATGACTAATAACTGATAACTAA
TAATTAATAACTGATAAAAG

Downstream 100 bases:

>100_bases
AGGAGCGGCTAGGTGTAGGTTGGGTTGAGGAAAGGAAACTCAACCAGCCATCAGCAGCTGAGTTAAACTGATTTAATAGG
ATATAGTTTAAGACATAGTT

Product: peptidase S8/S53 subtilisin kexin sedolisin

Products: NA

Alternate protein names: Ak.1 protease [H]

Number of amino acids: Translated: 666; Mature: 665

Protein sequence:

>666_residues
MPEISSIPGIKQLWAKTKGNSEVCVAVLDGLVDLKHPCFEGANLTQLPSLVQGQATPQSEMSLHGTHVASIIFGQPNSSV
SGIAPHCRGLIVPIFSDYHRRTSQLNLARAIEQAVNAGANIINISGGELTDYGEAEDWLNRAVSLCQNNNVLLVAAAGND
GCECLHVPAALPTVLAAGAMGENGQPLDYSNWGENYQTQGILALGENILGAEPGGGTRQLSGTSFATPVVSGVAALLMSL
QLQREEKPDSQKVRTALLKTAVPCHAQEKRRCLVGQMNISGAIAHITGETMSESEQDNSNGIEASCGCESTPEASLPGSV
GLENSLPTPADNGVVAAGVVEAGVTASQPLSSTNTSNTSNNQISAMPNNSQSNNSNGITPSQPPQDVTNIVYVIGTLGYD
FGTEARRDSFKQLMPAVTIGNTQIPANPYDARQMVDYLANNLSEAKSLIWTLNMELTPIYAIEAVGSFAREVYEALQELL
AGEVEAEDAERYIERVSIPGKLTGRTVKLFSGQVVPVIEPVSPRGIYGWRVNTLVGSALEAVRGEQAEADDEQMRRSLSS
FLNRVYYDLRNLGQTSQDRALNFAATNAFQAAQTFSTAVAAGMELDSIAVTKSPFCRMDSDCWDVQLKFFDPENNRRAKK
VFRFTIDVSDFIPVTLGEVRSWSSPY

Sequences:

>Translated_666_residues
MPEISSIPGIKQLWAKTKGNSEVCVAVLDGLVDLKHPCFEGANLTQLPSLVQGQATPQSEMSLHGTHVASIIFGQPNSSV
SGIAPHCRGLIVPIFSDYHRRTSQLNLARAIEQAVNAGANIINISGGELTDYGEAEDWLNRAVSLCQNNNVLLVAAAGND
GCECLHVPAALPTVLAAGAMGENGQPLDYSNWGENYQTQGILALGENILGAEPGGGTRQLSGTSFATPVVSGVAALLMSL
QLQREEKPDSQKVRTALLKTAVPCHAQEKRRCLVGQMNISGAIAHITGETMSESEQDNSNGIEASCGCESTPEASLPGSV
GLENSLPTPADNGVVAAGVVEAGVTASQPLSSTNTSNTSNNQISAMPNNSQSNNSNGITPSQPPQDVTNIVYVIGTLGYD
FGTEARRDSFKQLMPAVTIGNTQIPANPYDARQMVDYLANNLSEAKSLIWTLNMELTPIYAIEAVGSFAREVYEALQELL
AGEVEAEDAERYIERVSIPGKLTGRTVKLFSGQVVPVIEPVSPRGIYGWRVNTLVGSALEAVRGEQAEADDEQMRRSLSS
FLNRVYYDLRNLGQTSQDRALNFAATNAFQAAQTFSTAVAAGMELDSIAVTKSPFCRMDSDCWDVQLKFFDPENNRRAKK
VFRFTIDVSDFIPVTLGEVRSWSSPY
>Mature_665_residues
PEISSIPGIKQLWAKTKGNSEVCVAVLDGLVDLKHPCFEGANLTQLPSLVQGQATPQSEMSLHGTHVASIIFGQPNSSVS
GIAPHCRGLIVPIFSDYHRRTSQLNLARAIEQAVNAGANIINISGGELTDYGEAEDWLNRAVSLCQNNNVLLVAAAGNDG
CECLHVPAALPTVLAAGAMGENGQPLDYSNWGENYQTQGILALGENILGAEPGGGTRQLSGTSFATPVVSGVAALLMSLQ
LQREEKPDSQKVRTALLKTAVPCHAQEKRRCLVGQMNISGAIAHITGETMSESEQDNSNGIEASCGCESTPEASLPGSVG
LENSLPTPADNGVVAAGVVEAGVTASQPLSSTNTSNTSNNQISAMPNNSQSNNSNGITPSQPPQDVTNIVYVIGTLGYDF
GTEARRDSFKQLMPAVTIGNTQIPANPYDARQMVDYLANNLSEAKSLIWTLNMELTPIYAIEAVGSFAREVYEALQELLA
GEVEAEDAERYIERVSIPGKLTGRTVKLFSGQVVPVIEPVSPRGIYGWRVNTLVGSALEAVRGEQAEADDEQMRRSLSSF
LNRVYYDLRNLGQTSQDRALNFAATNAFQAAQTFSTAVAAGMELDSIAVTKSPFCRMDSDCWDVQLKFFDPENNRRAKKV
FRFTIDVSDFIPVTLGEVRSWSSPY

Specific function: Unknown

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI4506775, Length=266, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45550681, Length=266, Percent_Identity=28.1954887218045, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR009020 [H]

Pfam domain/function: PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 71277; Mature: 71145

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEISSIPGIKQLWAKTKGNSEVCVAVLDGLVDLKHPCFEGANLTQLPSLVQGQATPQSE
CCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCHHH
MSLHGTHVASIIFGQPNSSVSGIAPHCRGLIVPIFSDYHRRTSQLNLARAIEQAVNAGAN
HHCCCCEEEEEEECCCCCCCCCCCHHHCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IINISGGELTDYGEAEDWLNRAVSLCQNNNVLLVAAAGNDGCECLHVPAALPTVLAAGAM
EEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEECCHHHHHHHHHCCC
GENGQPLDYSNWGENYQTQGILALGENILGAEPGGGTRQLSGTSFATPVVSGVAALLMSL
CCCCCCCCCCCCCCCCCCCEEHHHCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHH
QLQREEKPDSQKVRTALLKTAVPCHAQEKRRCLVGQMNISGAIAHITGETMSESEQDNSN
HHHHHCCCCHHHHHHHHHHHCCCCCCHHHHCEEEEECCCCCEEEEECCCHHHCCCCCCCC
GIEASCGCESTPEASLPGSVGLENSLPTPADNGVVAAGVVEAGVTASQPLSSTNTSNTSN
CCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHCCCCCCCCCCCCCCCCCCC
NQISAMPNNSQSNNSNGITPSQPPQDVTNIVYVIGTLGYDFGTEARRDSFKQLMPAVTIG
CEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCEEEEC
NTQIPANPYDARQMVDYLANNLSEAKSLIWTLNMELTPIYAIEAVGSFAREVYEALQELL
CCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
AGEVEAEDAERYIERVSIPGKLTGRTVKLFSGQVVPVIEPVSPRGIYGWRVNTLVGSALE
CCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEECCCCCCCEECEEHHHHHHHHHH
AVRGEQAEADDEQMRRSLSSFLNRVYYDLRNLGQTSQDRALNFAATNAFQAAQTFSTAVA
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEHHHHHHHHHHHHHHHHHH
AGMELDSIAVTKSPFCRMDSDCWDVQLKFFDPENNRRAKKVFRFTIDVSDFIPVTLGEVR
HCCCCCCEEECCCCCCCCCCCCEEEEEEEECCCCCCCCEEEEEEEEEHHHCCCCCHHHHC
SWSSPY
CCCCCC
>Mature Secondary Structure 
PEISSIPGIKQLWAKTKGNSEVCVAVLDGLVDLKHPCFEGANLTQLPSLVQGQATPQSE
CCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCHHH
MSLHGTHVASIIFGQPNSSVSGIAPHCRGLIVPIFSDYHRRTSQLNLARAIEQAVNAGAN
HHCCCCEEEEEEECCCCCCCCCCCHHHCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IINISGGELTDYGEAEDWLNRAVSLCQNNNVLLVAAAGNDGCECLHVPAALPTVLAAGAM
EEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEECCHHHHHHHHHCCC
GENGQPLDYSNWGENYQTQGILALGENILGAEPGGGTRQLSGTSFATPVVSGVAALLMSL
CCCCCCCCCCCCCCCCCCCEEHHHCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHH
QLQREEKPDSQKVRTALLKTAVPCHAQEKRRCLVGQMNISGAIAHITGETMSESEQDNSN
HHHHHCCCCHHHHHHHHHHHCCCCCCHHHHCEEEEECCCCCEEEEECCCHHHCCCCCCCC
GIEASCGCESTPEASLPGSVGLENSLPTPADNGVVAAGVVEAGVTASQPLSSTNTSNTSN
CCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHCCCCCCCCCCCCCCCCCCC
NQISAMPNNSQSNNSNGITPSQPPQDVTNIVYVIGTLGYDFGTEARRDSFKQLMPAVTIG
CEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCEEEEC
NTQIPANPYDARQMVDYLANNLSEAKSLIWTLNMELTPIYAIEAVGSFAREVYEALQELL
CCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
AGEVEAEDAERYIERVSIPGKLTGRTVKLFSGQVVPVIEPVSPRGIYGWRVNTLVGSALE
CCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEECCCCCCCEECEEHHHHHHHHHH
AVRGEQAEADDEQMRRSLSSFLNRVYYDLRNLGQTSQDRALNFAATNAFQAAQTFSTAVA
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEHHHHHHHHHHHHHHHHHH
AGMELDSIAVTKSPFCRMDSDCWDVQLKFFDPENNRRAKKVFRFTIDVSDFIPVTLGEVR
HCCCCCCEEECCCCCCCCCCCCEEEEEEEECCCCCCCCEEEEEEEEEHHHCCCCCHHHHC
SWSSPY
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7993087; 10588904 [H]