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The map label for this gene is comEB [H]

Identifier: 113475737

GI number: 113475737

Start: 3251904

End: 3252446

Strand: Direct

Name: comEB [H]

Synonym: Tery_2084

Alternate gene names: 113475737

Gene position: 3251904-3252446 (Clockwise)

Preceding gene: 113475736

Following gene: 113475738

Centisome position: 41.96

GC content: 34.99

Gene sequence:

>543_bases
ATGAGAGAACAAATATATCAAAGACCAAGCTGGGATGAATACTTTTTAATGATTGCCAAATTAGCTGCTACTCGCTCAAC
TTGTTTAGCTTTTCCAGTAGGAGCAGTTATAGTTAAAGATAAACAAGTTTTGGCAACTGGTTATAATGGGCCTCCTTCTG
GTTCTAATCATTGTACAAGCCAAGGTTTTTGTTATCCTGAATTAAGTAGTTGTGATGCCAGTAAAGCTTTACCATCTCGT
TCTGTTCATGCAGAAGCTAATGCTATTGCTCAAGCGGCAAAACATGGTATTTGTACGAATGGAGCAATTATTTATGTCAC
CTTAGAACCCTGCATTTATTGCTTAAAATTAATTATTTCTTCTGGTATTAAAGAAGTTTTTTATGAGACGTCTTTTAATA
GTGGGGGAAAAGCGGCTTTAAGAGATTTATTTATTCAAGATGGTTTAGTTTCCCTTAAGCAAGTTTCTCTCTCAGATACA
ATTGCTAAAAAAGCAGCAACATTTCTACTTGATCCTACTTCTATTAGTAAAGTTTCTCGGTAG

Upstream 100 bases:

>100_bases
CCCAAATGGTAATAACGTCAGTTTTATCTGTTAAGGTAGAAGAAGTCAATCAATTAAGTACAACTCAAAGAGACATTAAT
GGATTTGGTTCAACAGGAAC

Downstream 100 bases:

>100_bases
TACTAAACAAGTAATGATTTTGTTTATTTACCTTATAGTAATTCAAGGGATATATCAACCTACATCCTGACATTTTTAAG
ACTACCAGTTTTTCAACTTG

Product: CMP/dCMP deaminase

Products: dUMP; NH3

Alternate protein names: NA

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MREQIYQRPSWDEYFLMIAKLAATRSTCLAFPVGAVIVKDKQVLATGYNGPPSGSNHCTSQGFCYPELSSCDASKALPSR
SVHAEANAIAQAAKHGICTNGAIIYVTLEPCIYCLKLIISSGIKEVFYETSFNSGGKAALRDLFIQDGLVSLKQVSLSDT
IAKKAATFLLDPTSISKVSR

Sequences:

>Translated_180_residues
MREQIYQRPSWDEYFLMIAKLAATRSTCLAFPVGAVIVKDKQVLATGYNGPPSGSNHCTSQGFCYPELSSCDASKALPSR
SVHAEANAIAQAAKHGICTNGAIIYVTLEPCIYCLKLIISSGIKEVFYETSFNSGGKAALRDLFIQDGLVSLKQVSLSDT
IAKKAATFLLDPTSISKVSR
>Mature_180_residues
MREQIYQRPSWDEYFLMIAKLAATRSTCLAFPVGAVIVKDKQVLATGYNGPPSGSNHCTSQGFCYPELSSCDASKALPSR
SVHAEANAIAQAAKHGICTNGAIIYVTLEPCIYCLKLIISSGIKEVFYETSFNSGGKAALRDLFIQDGLVSLKQVSLSDT
IAKKAATFLLDPTSISKVSR

Specific function: Dispensable for transformability [H]

COG id: COG2131

COG function: function code F; Deoxycytidylate deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI61742819, Length=146, Percent_Identity=35.6164383561644, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI61742821, Length=146, Percent_Identity=35.6164383561644, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321938, Length=125, Percent_Identity=40, Blast_Score=96, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24667298, Length=123, Percent_Identity=37.3983739837398, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24667302, Length=123, Percent_Identity=37.3983739837398, Blast_Score=71, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR013404
- InterPro:   IPR015517
- InterPro:   IPR016193
- InterPro:   IPR016473 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: 3.5.4.12

Molecular weight: Translated: 19389; Mature: 19389

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREQIYQRPSWDEYFLMIAKLAATRSTCLAFPVGAVIVKDKQVLATGYNGPPSGSNHCTS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEECCCCCCCCCCCCCC
QGFCYPELSSCDASKALPSRSVHAEANAIAQAAKHGICTNGAIIYVTLEPCIYCLKLIIS
CCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHH
SGIKEVFYETSFNSGGKAALRDLFIQDGLVSLKQVSLSDTIAKKAATFLLDPTSISKVSR
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHCCC
>Mature Secondary Structure
MREQIYQRPSWDEYFLMIAKLAATRSTCLAFPVGAVIVKDKQVLATGYNGPPSGSNHCTS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEECCCCCCCCCCCCCC
QGFCYPELSSCDASKALPSRSVHAEANAIAQAAKHGICTNGAIIYVTLEPCIYCLKLIIS
CCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHH
SGIKEVFYETSFNSGGKAALRDLFIQDGLVSLKQVSLSDTIAKKAATFLLDPTSISKVSR
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dCMP; H2O

Specific reaction: dCMP + H2O = dUMP + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7968523; 8969508; 9384377 [H]