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The map label for this gene is hscA [C]

Identifier: 113475342

GI number: 113475342

Start: 2521887

End: 2523671

Strand: Reverse

Name: hscA [C]

Synonym: Tery_1657

Alternate gene names: 113475342

Gene position: 2523671-2521887 (Counterclockwise)

Preceding gene: 113475343

Following gene: 113475341

Centisome position: 32.56

GC content: 40.11

Gene sequence:

>1785_bases
ATGATTGCTCCTTATGTTAAGGAAACAGTCCAACTGTGCAAGCAGTTGATCAAAAACGCCAATCTGAAAAAAAATCAGAT
AGATCAGATAATTTTAGTAGGCGGTAGTTGTAAGATTCCATTAGTGCAGAAAGTATTGGAGCAAGAACTAAATCTATCCG
TACTTCAGTTAGACGATCCAGACCTAGCAGTTTGCAAAGGTGCGGCAATTTATGAAGGATGGAATCCTGGCTATGCTCCA
CTGCAAGCTGGAATTGACCTTGAAGATATAGGCGATCATCAAGGGGCGATCGCTAAGTACAACCAAGCTTTACAAGAGAG
TCCCAACTATACCAAGGCGTATGTAGAGCGATCAGCAGCTTACACTAAGCTAGGAAAGCATAGCATCGCGATCGAAGATG
CTGATAGAGCAATACAATTTGAACCTGCCTATGCAAATGCTTATGTTCAGCGGGCAGATGTTGATTTTCGCTTAAATAAT
TACCAACAGGCAATTAGCATATATGACCGAGGACTAAGACTTAATCCGAACTTACCCCTAGCTTATTATGATCAGGGTCG
CTGTTTCTTACAGTTAGGTAAGAAGAAACAAGCACAAGATTGTTGGCATGAGGGATTGAAAATTATACCAAAAACTTCTG
ATGATTATAATACCCGTGGAGCAATTCTGTCTCAGCTAGAGGAGCATAGTAAAGCATTAGAAGAGTTTCAAGAAGCTCTT
CGGTTAAACAATAATAACATTGGCGCTTATGTTCATCGTGCAATGGCTCATTCTGCACTTGGAAACCATCAGGCTGTCAT
GGATAATTTTGATAAAGCACTGAGTCTGAATTCTAACGATGCTGATATTTATGGTTGGCGTGGAATCCATTTTGAACAGA
CTGGAGAGTTAAAAAAAGCAATTGAAGAGTTTGACAAAGCATTGCAAATAAATTATAAATATACGGTCGTGTACGCAGAG
CGGGGCAAGTGCTACTCTTGGTTGGGAAATCAGCAAGAAGCGATTAAAGATTTCAACCGTGCTTTAGAAATAGCTCCAAA
TAATAGTTATGCTTACGATGCTTTAGGAACTGCTTATCTTTATTTGAACGATATTGAGGAAGCAGAACAAAAATTCAAAA
AAGCCTTAAAGCTTAATCCCAATAACCCATTGGCTCACTGTGGCATAGGTGTAGTTTTCGGATTTAAAGAAAAGTGGGAA
GAGGCGATCGCTGCTTACCAAGAAGCCCTCTGTATTGAGCCCAAACTTGCACAAGGTTATGATGGTTTGGGACAGGCTTT
TTTTATGCAAGGCAAATTAGATGAGGCTATTCATGCTTATAAAAAAGCCCTCGGCATTGCTCCCAACTTTACAATAGTTC
ACAACAAGTTAGGCGTGGCTTTGGAGCAACAAAAAAAGGAGGATGAAGCAGTTGCCGCTTATAAAGAAGCGATTAGCCTC
GATCCTAACTTTGCAACAGCTCGCGCTAATTTAGGATATGCCCTGCTCAAGCAAGATAGAACGACTGATGGTATCGCCAA
TTTGAAAAAAGCAAGAGATTTATTCCAAACTCAAAACCAAGACAAAGAAGCTAGCAAGATAGATAATTTCTTGTGCAAGC
GAGAATCAGAGTCACACTATCGAAAGGGAGAAAAATTATCTAAACAAGGCAAATATCAAGAAGCAATTGCGGAATATGAA
GAAGCAATCCGCCTCGATCCTAGCCACGAAGATGCTCGTCAATCCTTAACAGCAGCAAAAGCATTATCGGGAGTGACTAA
CTTTTTCAAAAAACTGTTGTCATAA

Upstream 100 bases:

>100_bases
CTCAAGGAAAGTCTTAGCACAAAGGAGGAAAACTCATTTACATTACCTTTGCCTGGGGGGGTTACAAGAGTATCGATTAA
CCAGAAGTGCTTTTGAATCA

Downstream 100 bases:

>100_bases
GATCGTCTATTTACATAGCAAGGAGGATGGTTAATTGAACATATTTGATAACAATTCGCTAGTTACGGACAGCTTAGAAG
AGGCGGCCATTGAAGTTCTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 594; Mature: 594

Protein sequence:

>594_residues
MIAPYVKETVQLCKQLIKNANLKKNQIDQIILVGGSCKIPLVQKVLEQELNLSVLQLDDPDLAVCKGAAIYEGWNPGYAP
LQAGIDLEDIGDHQGAIAKYNQALQESPNYTKAYVERSAAYTKLGKHSIAIEDADRAIQFEPAYANAYVQRADVDFRLNN
YQQAISIYDRGLRLNPNLPLAYYDQGRCFLQLGKKKQAQDCWHEGLKIIPKTSDDYNTRGAILSQLEEHSKALEEFQEAL
RLNNNNIGAYVHRAMAHSALGNHQAVMDNFDKALSLNSNDADIYGWRGIHFEQTGELKKAIEEFDKALQINYKYTVVYAE
RGKCYSWLGNQQEAIKDFNRALEIAPNNSYAYDALGTAYLYLNDIEEAEQKFKKALKLNPNNPLAHCGIGVVFGFKEKWE
EAIAAYQEALCIEPKLAQGYDGLGQAFFMQGKLDEAIHAYKKALGIAPNFTIVHNKLGVALEQQKKEDEAVAAYKEAISL
DPNFATARANLGYALLKQDRTTDGIANLKKARDLFQTQNQDKEASKIDNFLCKRESESHYRKGEKLSKQGKYQEAIAEYE
EAIRLDPSHEDARQSLTAAKALSGVTNFFKKLLS

Sequences:

>Translated_594_residues
MIAPYVKETVQLCKQLIKNANLKKNQIDQIILVGGSCKIPLVQKVLEQELNLSVLQLDDPDLAVCKGAAIYEGWNPGYAP
LQAGIDLEDIGDHQGAIAKYNQALQESPNYTKAYVERSAAYTKLGKHSIAIEDADRAIQFEPAYANAYVQRADVDFRLNN
YQQAISIYDRGLRLNPNLPLAYYDQGRCFLQLGKKKQAQDCWHEGLKIIPKTSDDYNTRGAILSQLEEHSKALEEFQEAL
RLNNNNIGAYVHRAMAHSALGNHQAVMDNFDKALSLNSNDADIYGWRGIHFEQTGELKKAIEEFDKALQINYKYTVVYAE
RGKCYSWLGNQQEAIKDFNRALEIAPNNSYAYDALGTAYLYLNDIEEAEQKFKKALKLNPNNPLAHCGIGVVFGFKEKWE
EAIAAYQEALCIEPKLAQGYDGLGQAFFMQGKLDEAIHAYKKALGIAPNFTIVHNKLGVALEQQKKEDEAVAAYKEAISL
DPNFATARANLGYALLKQDRTTDGIANLKKARDLFQTQNQDKEASKIDNFLCKRESESHYRKGEKLSKQGKYQEAIAEYE
EAIRLDPSHEDARQSLTAAKALSGVTNFFKKLLS
>Mature_594_residues
MIAPYVKETVQLCKQLIKNANLKKNQIDQIILVGGSCKIPLVQKVLEQELNLSVLQLDDPDLAVCKGAAIYEGWNPGYAP
LQAGIDLEDIGDHQGAIAKYNQALQESPNYTKAYVERSAAYTKLGKHSIAIEDADRAIQFEPAYANAYVQRADVDFRLNN
YQQAISIYDRGLRLNPNLPLAYYDQGRCFLQLGKKKQAQDCWHEGLKIIPKTSDDYNTRGAILSQLEEHSKALEEFQEAL
RLNNNNIGAYVHRAMAHSALGNHQAVMDNFDKALSLNSNDADIYGWRGIHFEQTGELKKAIEEFDKALQINYKYTVVYAE
RGKCYSWLGNQQEAIKDFNRALEIAPNNSYAYDALGTAYLYLNDIEEAEQKFKKALKLNPNNPLAHCGIGVVFGFKEKWE
EAIAAYQEALCIEPKLAQGYDGLGQAFFMQGKLDEAIHAYKKALGIAPNFTIVHNKLGVALEQQKKEDEAVAAYKEAISL
DPNFATARANLGYALLKQDRTTDGIANLKKARDLFQTQNQDKEASKIDNFLCKRESESHYRKGEKLSKQGKYQEAIAEYE
EAIRLDPSHEDARQSLTAAKALSGVTNFFKKLLS

Specific function: Chaperone Involved In The Maturation Of Iron-Sulfur Cluster-Containing Proteins. Has A Low Intrinsic Atpase Activity Which Is Markedly Stimulated By Hscb. Involved In The Maturation Of Iscu. [C]

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 9 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307150, Length=423, Percent_Identity=25.2955082742317, Blast_Score=144, Evalue=3e-34,
Organism=Homo sapiens, GI32307148, Length=423, Percent_Identity=25.2955082742317, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI83415184, Length=309, Percent_Identity=24.9190938511327, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI301336134, Length=309, Percent_Identity=24.9190938511327, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI310123097, Length=372, Percent_Identity=24.1935483870968, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI310131789, Length=372, Percent_Identity=24.1935483870968, Blast_Score=94, Evalue=5e-19,
Organism=Homo sapiens, GI310110582, Length=372, Percent_Identity=24.1935483870968, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI170784867, Length=350, Percent_Identity=25.1428571428571, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI7706671, Length=242, Percent_Identity=28.5123966942149, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI296531396, Length=189, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI25952122, Length=316, Percent_Identity=26.2658227848101, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI54607135, Length=468, Percent_Identity=22.2222222222222, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI262206280, Length=357, Percent_Identity=22.4089635854342, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI196259772, Length=233, Percent_Identity=27.8969957081545, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI21361204, Length=233, Percent_Identity=27.8969957081545, Blast_Score=73, Evalue=1e-12,
Organism=Homo sapiens, GI196259776, Length=233, Percent_Identity=27.8969957081545, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI196259774, Length=233, Percent_Identity=27.8969957081545, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI196259770, Length=233, Percent_Identity=27.8969957081545, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI167466177, Length=289, Percent_Identity=24.9134948096886, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI167466175, Length=289, Percent_Identity=24.9134948096886, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI221219056, Length=300, Percent_Identity=25, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI22749211, Length=215, Percent_Identity=28.3720930232558, Blast_Score=71, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115532690, Length=468, Percent_Identity=24.5726495726496, Blast_Score=135, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI115532692, Length=468, Percent_Identity=24.5726495726496, Blast_Score=135, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI17560436, Length=361, Percent_Identity=23.8227146814404, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25147174, Length=242, Percent_Identity=24.7933884297521, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319589, Length=373, Percent_Identity=24.1286863270777, Blast_Score=85, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6319387, Length=267, Percent_Identity=22.0973782771536, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324601, Length=113, Percent_Identity=37.1681415929204, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17647755, Length=423, Percent_Identity=24.3498817966903, Blast_Score=139, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24585827, Length=423, Percent_Identity=24.3498817966903, Blast_Score=139, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24585829, Length=423, Percent_Identity=24.3498817966903, Blast_Score=139, Evalue=5e-33,
Organism=Drosophila melanogaster, GI161076610, Length=334, Percent_Identity=24.251497005988, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI19920486, Length=334, Percent_Identity=24.251497005988, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24581187, Length=362, Percent_Identity=25.1381215469613, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281364285, Length=362, Percent_Identity=25.1381215469613, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24647123, Length=243, Percent_Identity=25.5144032921811, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17137540, Length=403, Percent_Identity=21.0918114143921, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24583797, Length=207, Percent_Identity=25.6038647342995, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24583795, Length=207, Percent_Identity=25.6038647342995, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24583793, Length=207, Percent_Identity=25.6038647342995, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24652602, Length=322, Percent_Identity=22.6708074534161, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008940
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 66719; Mature: 66719

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAPYVKETVQLCKQLIKNANLKKNQIDQIILVGGSCKIPLVQKVLEQELNLSVLQLDDP
CCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEECCC
DLAVCKGAAIYEGWNPGYAPLQAGIDLEDIGDHQGAIAKYNQALQESPNYTKAYVERSAA
CHHHHCCCCEECCCCCCCCHHHCCCCHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHH
YTKLGKHSIAIEDADRAIQFEPAYANAYVQRADVDFRLNNYQQAISIYDRGLRLNPNLPL
HHHHCCCEEEEECCCCEEEECCHHHHHHHHHCCCCEEEHHHHHHHHHHHCCEEECCCCCE
AYYDQGRCFLQLGKKKQAQDCWHEGLKIIPKTSDDYNTRGAILSQLEEHSKALEEFQEAL
EEECCCCEEEECCCCCHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RLNNNNIGAYVHRAMAHSALGNHQAVMDNFDKALSLNSNDADIYGWRGIHFEQTGELKKA
HCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHEECCCCCCCEEEECCCCCCCCCHHHHH
IEEFDKALQINYKYTVVYAERGKCYSWLGNQQEAIKDFNRALEIAPNNSYAYDALGTAYL
HHHHHHHEEEEEEEEEEEECCCCCHHHCCCHHHHHHHHHHHEEECCCCCEEECCCCEEEE
YLNDIEEAEQKFKKALKLNPNNPLAHCGIGVVFGFKEKWEEAIAAYQEALCIEPKLAQGY
EEHHHHHHHHHHHHHHCCCCCCCHHHCCHHHEECCHHHHHHHHHHHHHHHCCCCCHHCCC
DGLGQAFFMQGKLDEAIHAYKKALGIAPNFTIVHNKLGVALEQQKKEDEAVAAYKEAISL
CCCCHHHEECCCHHHHHHHHHHHHCCCCCCEEEECHHCHHHHHHHHHHHHHHHHHHHHCC
DPNFATARANLGYALLKQDRTTDGIANLKKARDLFQTQNQDKEASKIDNFLCKRESESHY
CCCCHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHH
RKGEKLSKQGKYQEAIAEYEEAIRLDPSHEDARQSLTAAKALSGVTNFFKKLLS
HHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIAPYVKETVQLCKQLIKNANLKKNQIDQIILVGGSCKIPLVQKVLEQELNLSVLQLDDP
CCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEECCC
DLAVCKGAAIYEGWNPGYAPLQAGIDLEDIGDHQGAIAKYNQALQESPNYTKAYVERSAA
CHHHHCCCCEECCCCCCCCHHHCCCCHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHH
YTKLGKHSIAIEDADRAIQFEPAYANAYVQRADVDFRLNNYQQAISIYDRGLRLNPNLPL
HHHHCCCEEEEECCCCEEEECCHHHHHHHHHCCCCEEEHHHHHHHHHHHCCEEECCCCCE
AYYDQGRCFLQLGKKKQAQDCWHEGLKIIPKTSDDYNTRGAILSQLEEHSKALEEFQEAL
EEECCCCEEEECCCCCHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RLNNNNIGAYVHRAMAHSALGNHQAVMDNFDKALSLNSNDADIYGWRGIHFEQTGELKKA
HCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHEECCCCCCCEEEECCCCCCCCCHHHHH
IEEFDKALQINYKYTVVYAERGKCYSWLGNQQEAIKDFNRALEIAPNNSYAYDALGTAYL
HHHHHHHEEEEEEEEEEEECCCCCHHHCCCHHHHHHHHHHHEEECCCCCEEECCCCEEEE
YLNDIEEAEQKFKKALKLNPNNPLAHCGIGVVFGFKEKWEEAIAAYQEALCIEPKLAQGY
EEHHHHHHHHHHHHHHCCCCCCCHHHCCHHHEECCHHHHHHHHHHHHHHHCCCCCHHCCC
DGLGQAFFMQGKLDEAIHAYKKALGIAPNFTIVHNKLGVALEQQKKEDEAVAAYKEAISL
CCCCHHHEECCCHHHHHHHHHHHHCCCCCCEEEECHHCHHHHHHHHHHHHHHHHHHHHCC
DPNFATARANLGYALLKQDRTTDGIANLKKARDLFQTQNQDKEASKIDNFLCKRESESHY
CCCCHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHH
RKGEKLSKQGKYQEAIAEYEEAIRLDPSHEDARQSLTAAKALSGVTNFFKKLLS
HHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087; 9697413 [H]