Click here to switch to the map view.

The map label for this gene is iniA [H]

Identifier: 113475339

GI number: 113475339

Start: 2517954

End: 2520014

Strand: Reverse

Name: iniA [H]

Synonym: Tery_1654

Alternate gene names: 113475339

Gene position: 2520014-2517954 (Counterclockwise)

Preceding gene: 113475340

Following gene: 113475338

Centisome position: 32.52

GC content: 44.44

Gene sequence:

>2061_bases
ATGCCTACCTACCAAGCACGATATCAGGAACAGAAGCAGCAGACCCTAAAGCTGTTGCAATCAGCAATATCCTTTGCCAA
AACCTATAAATACAGAGATATAGAGCGGCGTCTGGGCGAAGCTCAAAAACGTCTACTTGAGGGTAAGTTGCTGGTTGTAG
TCTGCGGTGAGTTCAAGGAAGGAAAATCTAGCTTGATTAATGCACTTCTCAAGGAAGCCAATGACGACTTATTCCCGGTA
GATGCTGATATTGCCACCGGTATTGTATCCACGATCGCTTACGGAGAAAGGGAACAAATTACGGTTATCCTGGGAAAACC
AGGTAAAGAAAAGAAAGAGAAAATTCAACGCCAGGAAATAGGCAATTATGCTAACGAGAAATTCAATAAAGGAAACAAGC
GTCAAGCTCGGATGCTGGTTATAGAATCGCCTAACCAAAAACTGAAGGATGGTTTAGTATTGGTGGATACGCCTGGCGTG
GGGGGACTCAATACCCAACATACGGGAATTACTTACAGTTTCATCCCCGAAGCCGATGCCATCCTTTTTGTTAGCGATGT
CAAAAACCCTCTGTCAGAAGACGAACTCAAATTTCTGAAATTTATTGTCGATCGCTGTCCTAATGTTATTTCCAACGTTA
TCTTCGTTGTTACCAAAATAGATTCTAAAGCAGACTACCAAACTATCGTGGCGAATAACAGGGAAAAACTAGCCCAAGTG
CTACAGCGTCCTGGCAATGAAATTCCGATCGTCCCTGTATCTAGCCACAACTACCTTGACTACTTAAAGCATGAAGATGA
GGAAGACTTAGAGGATAGCAACTTCATAGCATTAGAGTCAGAATTGGGGAAACTACTCACCCAAGAGAAGGGCTACATTT
TGCTGATCCGTGCTCTGGGAGAACTGGGACCAGCTTTAAGGGATATGAAAATGCCGATCCAGGCTGAATTGTCAACTTGC
CAGCAACAAAGCAAAGAAGAGATTGATAAGCTGGAAAGCCAGTTCCAGAATGAAAAGCAACGCTTTCAAGATCTCCAAAA
TGACAACACCAACTGGCAAAAGCAGTTAAGTCGCGGTATCGAAGATATCAGCATGGAATTGTCCGCTCAATTGCGCAGTG
GCTTTACCAAAGTTCAGGGGTGGGCAAATGACTATATGAAAGATAGCAAATTGTTAGAGAAACCAGCGGAGATTGCTAAG
TTGGTCGAGCGGGATATTGATACCCTGATGTCTGACATAGGAAAGCAAGTTAGCAGCAAAGCAGCCAGCTTGCATTACCA
AATTGAGACATCAAGTGGATTGGAGCTTGGTATCTCTAATCTTGACTCTTTAGACTGGGAAAAAACTGAACTATCAACAG
ATAGCATAGAGATTAAGAAGTCAGGATGGTGGGAAAAAACCCTGAGCGTAACGCGCAGTGGGATGTTTAATGCTACGGCC
GGGGGAACTCTTGCTAGTGCGGTAGGAGGAGCAGTTGGTGCAGGTATCGGCTTTCTGTTTGGTGGTGTGGGAGCCGGGCC
CGGAGCTGTTATTGGTTCGTCAATTGGTGCTGCAATTGGTGGAATAGCGGGACTTACATCTGGAGTAGTACAAGGAGTAT
CCCAAGTTAAGAAACAGGATACAGCTGCCGCTCAAAGAGAAATCAACCCGCACATCCAGCAGTTTATCAGAGAAAGTCAA
GAGCTTTGTCAACAGTCTTTGAATAAAACTGTTATACAATTAAAGCGGGCGATGACAGATGATTTGAGCGAAAAGATCGG
ACAGTTAAAGCAAAATTGCGATCGCACGTTACGTTCTATTCAGGAAACTCGCAAGCTCACCGAGCGAGAGAAGCAAGAAA
AACTCAAGCAGCTAGCAATTCCTTTGCAGCAACTCAACAAACTCTACAACAGCGTCGAAAATCTAGCCAATGCCACAATT
TCCCAAAAGGAAACTGTCGTTCAGACCGAAACTATGGCAAATTTTCAACCAAAATCGGATGGGGATTCGCAGGTGTTGGA
AGCAAGTCAAATCGACGAACCGAGCAATGCTGATTATGGAGAGGACTGGGCAGATGGATAA

Upstream 100 bases:

>100_bases
CTTTGATGGAACCTTCCCTGGAGCCGTATTATCGCGTTCTAGGCTCAAAGTTTTTTGACCACTTCTTAACCAAAAACTAA
TTAATTTTTGCGAGGAAAGT

Downstream 100 bases:

>100_bases
TCGGGCATTACGCGATCGCGCTGAAGAGGTATTTCAGTTTGCTCTTGGTTGCACCATGAATCGCCCCAAGTTGCAGAACC
TATACCGAAAGATTGATCAG

Product: dynamin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 686; Mature: 685

Protein sequence:

>686_residues
MPTYQARYQEQKQQTLKLLQSAISFAKTYKYRDIERRLGEAQKRLLEGKLLVVVCGEFKEGKSSLINALLKEANDDLFPV
DADIATGIVSTIAYGEREQITVILGKPGKEKKEKIQRQEIGNYANEKFNKGNKRQARMLVIESPNQKLKDGLVLVDTPGV
GGLNTQHTGITYSFIPEADAILFVSDVKNPLSEDELKFLKFIVDRCPNVISNVIFVVTKIDSKADYQTIVANNREKLAQV
LQRPGNEIPIVPVSSHNYLDYLKHEDEEDLEDSNFIALESELGKLLTQEKGYILLIRALGELGPALRDMKMPIQAELSTC
QQQSKEEIDKLESQFQNEKQRFQDLQNDNTNWQKQLSRGIEDISMELSAQLRSGFTKVQGWANDYMKDSKLLEKPAEIAK
LVERDIDTLMSDIGKQVSSKAASLHYQIETSSGLELGISNLDSLDWEKTELSTDSIEIKKSGWWEKTLSVTRSGMFNATA
GGTLASAVGGAVGAGIGFLFGGVGAGPGAVIGSSIGAAIGGIAGLTSGVVQGVSQVKKQDTAAAQREINPHIQQFIRESQ
ELCQQSLNKTVIQLKRAMTDDLSEKIGQLKQNCDRTLRSIQETRKLTEREKQEKLKQLAIPLQQLNKLYNSVENLANATI
SQKETVVQTETMANFQPKSDGDSQVLEASQIDEPSNADYGEDWADG

Sequences:

>Translated_686_residues
MPTYQARYQEQKQQTLKLLQSAISFAKTYKYRDIERRLGEAQKRLLEGKLLVVVCGEFKEGKSSLINALLKEANDDLFPV
DADIATGIVSTIAYGEREQITVILGKPGKEKKEKIQRQEIGNYANEKFNKGNKRQARMLVIESPNQKLKDGLVLVDTPGV
GGLNTQHTGITYSFIPEADAILFVSDVKNPLSEDELKFLKFIVDRCPNVISNVIFVVTKIDSKADYQTIVANNREKLAQV
LQRPGNEIPIVPVSSHNYLDYLKHEDEEDLEDSNFIALESELGKLLTQEKGYILLIRALGELGPALRDMKMPIQAELSTC
QQQSKEEIDKLESQFQNEKQRFQDLQNDNTNWQKQLSRGIEDISMELSAQLRSGFTKVQGWANDYMKDSKLLEKPAEIAK
LVERDIDTLMSDIGKQVSSKAASLHYQIETSSGLELGISNLDSLDWEKTELSTDSIEIKKSGWWEKTLSVTRSGMFNATA
GGTLASAVGGAVGAGIGFLFGGVGAGPGAVIGSSIGAAIGGIAGLTSGVVQGVSQVKKQDTAAAQREINPHIQQFIRESQ
ELCQQSLNKTVIQLKRAMTDDLSEKIGQLKQNCDRTLRSIQETRKLTEREKQEKLKQLAIPLQQLNKLYNSVENLANATI
SQKETVVQTETMANFQPKSDGDSQVLEASQIDEPSNADYGEDWADG
>Mature_685_residues
PTYQARYQEQKQQTLKLLQSAISFAKTYKYRDIERRLGEAQKRLLEGKLLVVVCGEFKEGKSSLINALLKEANDDLFPVD
ADIATGIVSTIAYGEREQITVILGKPGKEKKEKIQRQEIGNYANEKFNKGNKRQARMLVIESPNQKLKDGLVLVDTPGVG
GLNTQHTGITYSFIPEADAILFVSDVKNPLSEDELKFLKFIVDRCPNVISNVIFVVTKIDSKADYQTIVANNREKLAQVL
QRPGNEIPIVPVSSHNYLDYLKHEDEEDLEDSNFIALESELGKLLTQEKGYILLIRALGELGPALRDMKMPIQAELSTCQ
QQSKEEIDKLESQFQNEKQRFQDLQNDNTNWQKQLSRGIEDISMELSAQLRSGFTKVQGWANDYMKDSKLLEKPAEIAKL
VERDIDTLMSDIGKQVSSKAASLHYQIETSSGLELGISNLDSLDWEKTELSTDSIEIKKSGWWEKTLSVTRSGMFNATAG
GTLASAVGGAVGAGIGFLFGGVGAGPGAVIGSSIGAAIGGIAGLTSGVVQGVSQVKKQDTAAAQREINPHIQQFIRESQE
LCQQSLNKTVIQLKRAMTDDLSEKIGQLKQNCDRTLRSIQETRKLTEREKQEKLKQLAIPLQQLNKLYNSVENLANATIS
QKETVVQTETMANFQPKSDGDSQVLEASQIDEPSNADYGEDWADG

Specific function: Participates in the development of tolerance to both isoniazid and ethambutol. May function through a MDR-pump like mechanism, although it does not appear to directly transport isoniazid from the cell [H]

COG id: COG0699

COG function: function code R; Predicted GTPases (dynamin-related)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001401 [H]

Pfam domain/function: PF00350 Dynamin_N [H]

EC number: NA

Molecular weight: Translated: 76026; Mature: 75895

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTYQARYQEQKQQTLKLLQSAISFAKTYKYRDIERRLGEAQKRLLEGKLLVVVCGEFKE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
GKSSLINALLKEANDDLFPVDADIATGIVSTIAYGEREQITVILGKPGKEKKEKIQRQEI
CHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHH
GNYANEKFNKGNKRQARMLVIESPNQKLKDGLVLVDTPGVGGLNTQHTGITYSFIPEADA
HHHHHHHCCCCCCCEEEEEEEECCCHHHHCCEEEEECCCCCCCCCCCCCEEEEECCCCCC
ILFVSDVKNPLSEDELKFLKFIVDRCPNVISNVIFVVTKIDSKADYQTIVANNREKLAQV
EEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHEEHEECCCCCCHHHHHHCCHHHHHHH
LQRPGNEIPIVPVSSHNYLDYLKHEDEEDLEDSNFIALESELGKLLTQEKGYILLIRALG
HHCCCCCCCEEECCCCCHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCEEEHHHHH
ELGPALRDMKMPIQAELSTCQQQSKEEIDKLESQFQNEKQRFQDLQNDNTNWQKQLSRGI
HHCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCH
EDISMELSAQLRSGFTKVQGWANDYMKDSKLLEKPAEIAKLVERDIDTLMSDIGKQVSSK
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AASLHYQIETSSGLELGISNLDSLDWEKTELSTDSIEIKKSGWWEKTLSVTRSGMFNATA
HHHEEEEEECCCCCHHCCCCCCCCCCCHHHCCCCCEEECCCCCHHHHHHHHHCCCCCCCC
GGTLASAVGGAVGAGIGFLFGGVGAGPGAVIGSSIGAAIGGIAGLTSGVVQGVSQVKKQD
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAAAQREINPHIQQFIRESQELCQQSLNKTVIQLKRAMTDDLSEKIGQLKQNCDRTLRSI
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QETRKLTEREKQEKLKQLAIPLQQLNKLYNSVENLANATISQKETVVQTETMANFQPKSD
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GDSQVLEASQIDEPSNADYGEDWADG
CHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PTYQARYQEQKQQTLKLLQSAISFAKTYKYRDIERRLGEAQKRLLEGKLLVVVCGEFKE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
GKSSLINALLKEANDDLFPVDADIATGIVSTIAYGEREQITVILGKPGKEKKEKIQRQEI
CHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHH
GNYANEKFNKGNKRQARMLVIESPNQKLKDGLVLVDTPGVGGLNTQHTGITYSFIPEADA
HHHHHHHCCCCCCCEEEEEEEECCCHHHHCCEEEEECCCCCCCCCCCCCEEEEECCCCCC
ILFVSDVKNPLSEDELKFLKFIVDRCPNVISNVIFVVTKIDSKADYQTIVANNREKLAQV
EEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHEEHEECCCCCCHHHHHHCCHHHHHHH
LQRPGNEIPIVPVSSHNYLDYLKHEDEEDLEDSNFIALESELGKLLTQEKGYILLIRALG
HHCCCCCCCEEECCCCCHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCEEEHHHHH
ELGPALRDMKMPIQAELSTCQQQSKEEIDKLESQFQNEKQRFQDLQNDNTNWQKQLSRGI
HHCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCH
EDISMELSAQLRSGFTKVQGWANDYMKDSKLLEKPAEIAKLVERDIDTLMSDIGKQVSSK
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AASLHYQIETSSGLELGISNLDSLDWEKTELSTDSIEIKKSGWWEKTLSVTRSGMFNATA
HHHEEEEEECCCCCHHCCCCCCCCCCCHHHCCCCCEEECCCCCHHHHHHHHHCCCCCCCC
GGTLASAVGGAVGAGIGFLFGGVGAGPGAVIGSSIGAAIGGIAGLTSGVVQGVSQVKKQD
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAAAQREINPHIQQFIRESQELCQQSLNKTVIQLKRAMTDDLSEKIGQLKQNCDRTLRSI
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QETRKLTEREKQEKLKQLAIPLQQLNKLYNSVENLANATISQKETVVQTETMANFQPKSD
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GDSQVLEASQIDEPSNADYGEDWADG
CHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]