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The map label for this gene is holB [H]

Identifier: 113475257

GI number: 113475257

Start: 2390588

End: 2391550

Strand: Direct

Name: holB [H]

Synonym: Tery_1565

Alternate gene names: 113475257

Gene position: 2390588-2391550 (Clockwise)

Preceding gene: 113475256

Following gene: 113475260

Centisome position: 30.85

GC content: 41.74

Gene sequence:

>963_bases
TTGATTTTTGACTTTATTAATATTATCGGGCAAAACCAAGCCATAGAATTATTAACCCAAGCAATGGCTCATCAACGCAT
TGCCCCAGCTTATCTATTTGCTGGACCTCCAGGAGTCGGCCGAGCTTTAACTGCTCAATGTTTTATCCAACTTCTATTCT
CTCATACCAACTCTTTCCCTCCAAATAGTTCATCCCTAAAAAGCCGCATCCAAAAAAGAAACCATCCAGACCTGTTATGG
TTAGAGCCAACATACTTACACCAAGGAAAGCTTTTTTCAGCAACAGAAGCAGCTGCAGCGGGGGTAAAACGTAAGTCCCC
TCCTCAAATACGCTTAGAACAAGTGCGCGATATTGGTCAATTTCTGAGTCGTCCTCCCCTACAAGCAGCAAGAGCAGTTG
TGGTGTTGCAACAAGCTGAGACAATGGGAGAAAATGCTGCCAATGGTTTATTGAAGATTTTGGAAGAGCCAGGGAAACGA
GCAACCTTAATTTTAATTGCCCCTGGAGTTGATGCATTGTTGCCAACTTTGGTGTCCCGGTGTCAACGTATTCCCTTTTA
TCGCTTGACTCAGGAGAATATGAAGTTAGTCTTGGAAAAGGTGGGTTATGGAAAAATTTTAGATCAGCCAGAAGTCATGG
AAATGGCTCAAGGAAGTCCTGGAGAAGCGATCGCTTGTTGGCAGCAACTACAACAAATTCCAGCAGATATTCTTGAAGTT
GCAACTCAGGGTATTAGAGATATTCCTCAAGCATTGACATTAGCACGGGATATTAGTAAAAGTTTAGATACGGAAGCACA
GTTATGGTTGATAGATTATTTACAGCATTGTTATTGGAGACAACACCCCTTAATTGGAGTGGAGTGTCTGAAACATTTGG
AAATGGCAAGAACATATTTACTGTCCTATGTACAACCTAGGTTGGTTTGGGAATGTACCTTAATGGCTATTTGTTCAAGT
TGA

Upstream 100 bases:

>100_bases
CTGTAATAATCTATTATTGAAAAGGATTTCCTGTTGGTGTAGTCTAGCCTCAGCAAATTATCTTATGTTCATTTAACTTT
TAACTTTTAACTTTTAACTT

Downstream 100 bases:

>100_bases
AATTTTTTAGACCCAGTAGCCTGGGTATTTACGACTAAAATTTTTGAGAATATAAGTGGTGAAAGATATTAGAATTTTTA
GAATTTCCGAAAAATTTTCC

Product: DNA polymerase III subunit delta'

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MIFDFINIIGQNQAIELLTQAMAHQRIAPAYLFAGPPGVGRALTAQCFIQLLFSHTNSFPPNSSSLKSRIQKRNHPDLLW
LEPTYLHQGKLFSATEAAAAGVKRKSPPQIRLEQVRDIGQFLSRPPLQAARAVVVLQQAETMGENAANGLLKILEEPGKR
ATLILIAPGVDALLPTLVSRCQRIPFYRLTQENMKLVLEKVGYGKILDQPEVMEMAQGSPGEAIACWQQLQQIPADILEV
ATQGIRDIPQALTLARDISKSLDTEAQLWLIDYLQHCYWRQHPLIGVECLKHLEMARTYLLSYVQPRLVWECTLMAICSS

Sequences:

>Translated_320_residues
MIFDFINIIGQNQAIELLTQAMAHQRIAPAYLFAGPPGVGRALTAQCFIQLLFSHTNSFPPNSSSLKSRIQKRNHPDLLW
LEPTYLHQGKLFSATEAAAAGVKRKSPPQIRLEQVRDIGQFLSRPPLQAARAVVVLQQAETMGENAANGLLKILEEPGKR
ATLILIAPGVDALLPTLVSRCQRIPFYRLTQENMKLVLEKVGYGKILDQPEVMEMAQGSPGEAIACWQQLQQIPADILEV
ATQGIRDIPQALTLARDISKSLDTEAQLWLIDYLQHCYWRQHPLIGVECLKHLEMARTYLLSYVQPRLVWECTLMAICSS
>Mature_320_residues
MIFDFINIIGQNQAIELLTQAMAHQRIAPAYLFAGPPGVGRALTAQCFIQLLFSHTNSFPPNSSSLKSRIQKRNHPDLLW
LEPTYLHQGKLFSATEAAAAGVKRKSPPQIRLEQVRDIGQFLSRPPLQAARAVVVLQQAETMGENAANGLLKILEEPGKR
ATLILIAPGVDALLPTLVSRCQRIPFYRLTQENMKLVLEKVGYGKILDQPEVMEMAQGSPGEAIACWQQLQQIPADILEV
ATQGIRDIPQALTLARDISKSLDTEAQLWLIDYLQHCYWRQHPLIGVECLKHLEMARTYLLSYVQPRLVWECTLMAICSS

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG0470

COG function: function code L; ATPase involved in DNA replication

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004622 [H]

Pfam domain/function: NA

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 35797; Mature: 35797

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFDFINIIGQNQAIELLTQAMAHQRIAPAYLFAGPPGVGRALTAQCFIQLLFSHTNSFP
CHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHEECCCCCCCHHHHHHHHHHHHHHHCCCCC
PNSSSLKSRIQKRNHPDLLWLEPTYLHQGKLFSATEAAAAGVKRKSPPQIRLEQVRDIGQ
CCHHHHHHHHHHCCCCCEEEECHHHHCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHH
FLSRPPLQAARAVVVLQQAETMGENAANGLLKILEEPGKRATLILIAPGVDALLPTLVSR
HHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHH
CQRIPFYRLTQENMKLVLEKVGYGKILDQPEVMEMAQGSPGEAIACWQQLQQIPADILEV
HHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
ATQGIRDIPQALTLARDISKSLDTEAQLWLIDYLQHCYWRQHPLIGVECLKHLEMARTYL
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LSYVQPRLVWECTLMAICSS
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIFDFINIIGQNQAIELLTQAMAHQRIAPAYLFAGPPGVGRALTAQCFIQLLFSHTNSFP
CHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHEECCCCCCCHHHHHHHHHHHHHHHCCCCC
PNSSSLKSRIQKRNHPDLLWLEPTYLHQGKLFSATEAAAAGVKRKSPPQIRLEQVRDIGQ
CCHHHHHHHHHHCCCCCEEEECHHHHCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHH
FLSRPPLQAARAVVVLQQAETMGENAANGLLKILEEPGKRATLILIAPGVDALLPTLVSR
HHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHH
CQRIPFYRLTQENMKLVLEKVGYGKILDQPEVMEMAQGSPGEAIACWQQLQQIPADILEV
HHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
ATQGIRDIPQALTLARDISKSLDTEAQLWLIDYLQHCYWRQHPLIGVECLKHLEMARTYL
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LSYVQPRLVWECTLMAICSS
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]