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The map label for this gene is clpP1 [H]

Identifier: 113475211

GI number: 113475211

Start: 2300636

End: 2301247

Strand: Reverse

Name: clpP1 [H]

Synonym: Tery_1514

Alternate gene names: 113475211

Gene position: 2301247-2300636 (Counterclockwise)

Preceding gene: 113475212

Following gene: 113475208

Centisome position: 29.69

GC content: 39.05

Gene sequence:

>612_bases
ATGATTCCAACCGTTATTGAACAATCTGGCCGTGGCGAAAGAGCCTTCGATATTTACTCTCGACTATTACGCGATCGCAT
AATCTATCTAGGAGAAGCGATAGACTCTGAATTGGCCAACCTAATCGTAGGCCAATTATTATATTTAGACTCAGAAGACC
CAGAAAAAGATATTTATCTCTATATAAACTCTCCTGGCGGTTCTGTTAGTGCCGGGATGGGTATTTATGACACCATGAGA
CACGTTCGACCTGATGTCTGTACTATTTGTATGGGAATAGCTGCTAGTATGGGAGCATTTCTTCTGAGTGGAGGAACAAA
AGGCAAAAGAATGAGTCTACCCCACTCCCGAATTATGATTCATCAACCATTAGGTGGTGCCCAAGGTCAAGCCACAGATA
TTGAAATCCAAGCAAAAGAGATTTTATACCTCAAAAAATATCTTAATGAATGTTTAGCAGAACACACAGGCCAATCTATA
GAAAAAATTACCGAAGATACAGAAAGAGACTTTTTTATGTCAGCCACAGAAGCAATGGAATACGGAATAATAGACCAAGT
TTATAACCGTAATCCCTCTAATTCTCAACCTATATCTCCTATTAAGGAATAA

Upstream 100 bases:

>100_bases
TAAAAATAACCGTACCTTAAAAATATTGACAAATATTATATTATATATTAAACAGCACCAATAATTTTCACTTTGAATTT
TAACTTTTAGCTGAAAAAAT

Downstream 100 bases:

>100_bases
ATAAATAGTAGAAAACAGTTAAGGCTAGTGGATTAGTTCTCAAAGCATTGACAAATAAAAGCTTTAGCCAAGTTAAGAAG
TCTTAAAAAGTACCAGAAGT

Product: ATP-dependent Clp protease proteolytic subunit ClpP

Products: NA

Alternate protein names: Endopeptidase Clp 1 [H]

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MIPTVIEQSGRGERAFDIYSRLLRDRIIYLGEAIDSELANLIVGQLLYLDSEDPEKDIYLYINSPGGSVSAGMGIYDTMR
HVRPDVCTICMGIAASMGAFLLSGGTKGKRMSLPHSRIMIHQPLGGAQGQATDIEIQAKEILYLKKYLNECLAEHTGQSI
EKITEDTERDFFMSATEAMEYGIIDQVYNRNPSNSQPISPIKE

Sequences:

>Translated_203_residues
MIPTVIEQSGRGERAFDIYSRLLRDRIIYLGEAIDSELANLIVGQLLYLDSEDPEKDIYLYINSPGGSVSAGMGIYDTMR
HVRPDVCTICMGIAASMGAFLLSGGTKGKRMSLPHSRIMIHQPLGGAQGQATDIEIQAKEILYLKKYLNECLAEHTGQSI
EKITEDTERDFFMSATEAMEYGIIDQVYNRNPSNSQPISPIKE
>Mature_203_residues
MIPTVIEQSGRGERAFDIYSRLLRDRIIYLGEAIDSELANLIVGQLLYLDSEDPEKDIYLYINSPGGSVSAGMGIYDTMR
HVRPDVCTICMGIAASMGAFLLSGGTKGKRMSLPHSRIMIHQPLGGAQGQATDIEIQAKEILYLKKYLNECLAEHTGQSI
EKITEDTERDFFMSATEAMEYGIIDQVYNRNPSNSQPISPIKE

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Homo sapiens, GI5174419, Length=196, Percent_Identity=56.6326530612245, Blast_Score=231, Evalue=3e-61,
Organism=Escherichia coli, GI1786641, Length=192, Percent_Identity=65.1041666666667, Blast_Score=272, Evalue=1e-74,
Organism=Caenorhabditis elegans, GI17538017, Length=192, Percent_Identity=52.6041666666667, Blast_Score=209, Evalue=7e-55,
Organism=Drosophila melanogaster, GI20129427, Length=200, Percent_Identity=51.5, Blast_Score=213, Evalue=6e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907
- InterPro:   IPR018215 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 22555; Mature: 22555

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS00381 CLP_PROTEASE_SER ; PS00382 CLP_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPTVIEQSGRGERAFDIYSRLLRDRIIYLGEAIDSELANLIVGQLLYLDSEDPEKDIYL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
YINSPGGSVSAGMGIYDTMRHVRPDVCTICMGIAASMGAFLLSGGTKGKRMSLPHSRIMI
EEECCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCEEEE
HQPLGGAQGQATDIEIQAKEILYLKKYLNECLAEHTGQSIEKITEDTERDFFMSATEAME
ECCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
YGIIDQVYNRNPSNSQPISPIKE
HHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIPTVIEQSGRGERAFDIYSRLLRDRIIYLGEAIDSELANLIVGQLLYLDSEDPEKDIYL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
YINSPGGSVSAGMGIYDTMRHVRPDVCTICMGIAASMGAFLLSGGTKGKRMSLPHSRIMI
EEECCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCEEEE
HQPLGGAQGQATDIEIQAKEILYLKKYLNECLAEHTGQSIEKITEDTERDFFMSATEAME
ECCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
YGIIDQVYNRNPSNSQPISPIKE
HHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA