Click here to switch to the map view.

The map label for this gene is fbp [H]

Identifier: 113475169

GI number: 113475169

Start: 2226624

End: 2227235

Strand: Reverse

Name: fbp [H]

Synonym: Tery_1467

Alternate gene names: 113475169

Gene position: 2227235-2226624 (Counterclockwise)

Preceding gene: 113475170

Following gene: 113475168

Centisome position: 28.74

GC content: 38.56

Gene sequence:

>612_bases
TTGGAGACCAAACCCTTACAGTTTTTTTTGCGAGTTAAATTAGGAGGATTAATTTTGCGCGGAATTATTATTAGTTTGGG
AATAGCAATAGTCTGTGGTTTGGTTTTGATTATTTCTCAAATTATAGGTTCGGGAAAAGATGTGGTTGCTTCTCAAAATA
CACCAGATACTATAGGTTCTACTGAAATTCAGGAGCAAGTGGCAGAAGGTACTATACTAAATCCAACAATTACAATGGCA
GAAAATATTATGGCTCAAGATGATGAAAAAGTTACTACTACTGATTCTGGTCTTCAGTATGTGGACGTGGTAGAAGGAGA
TGGTGCTACTCCTCAAAGGGGTCAGACAGTTGTGGTTCACTATACTGGAACTTTAGAGGATGGTTCTAAGTTTGATAGTT
CTCGCGATCGCAATCAACCTTTCCAATTTAAAGTTGGGGTAGGTCAAGTTATTAAGGGTTGGGATGAAGGAGTAGGTAGT
ATGAAAGTTGGTGGACGTCGAAAGTTGATTATACCATCGGATTTAGGGTATGGTTCCCGTGGTGCTGGTGGAGTCATACC
TCCTAATGCTACTCTTATTTTTGATGTAGAATTATTGAGAATTGCTAATTGA

Upstream 100 bases:

>100_bases
TTTTTTTATAAGCATTTGTGGTTGATAATATAATAATCTGTCCATAGGTTGTAATATCTTATCTTAGGGGTTTGGAGACC
AAACCTTAGGGAAACGAGAT

Downstream 100 bases:

>100_bases
CATATTCTTGATTTTGTGCATTGGTAACAAAGCGGGATTCTTCAGTCAGGGAAGTCCTGAGGGTAGTTCTGAGGTTAGAT
AATATTCTCCCCCTCTGTTG

Product: peptidylprolyl isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
METKPLQFFLRVKLGGLILRGIIISLGIAIVCGLVLIISQIIGSGKDVVASQNTPDTIGSTEIQEQVAEGTILNPTITMA
ENIMAQDDEKVTTTDSGLQYVDVVEGDGATPQRGQTVVVHYTGTLEDGSKFDSSRDRNQPFQFKVGVGQVIKGWDEGVGS
MKVGGRRKLIIPSDLGYGSRGAGGVIPPNATLIFDVELLRIAN

Sequences:

>Translated_203_residues
METKPLQFFLRVKLGGLILRGIIISLGIAIVCGLVLIISQIIGSGKDVVASQNTPDTIGSTEIQEQVAEGTILNPTITMA
ENIMAQDDEKVTTTDSGLQYVDVVEGDGATPQRGQTVVVHYTGTLEDGSKFDSSRDRNQPFQFKVGVGQVIKGWDEGVGS
MKVGGRRKLIIPSDLGYGSRGAGGVIPPNATLIFDVELLRIAN
>Mature_203_residues
METKPLQFFLRVKLGGLILRGIIISLGIAIVCGLVLIISQIIGSGKDVVASQNTPDTIGSTEIQEQVAEGTILNPTITMA
ENIMAQDDEKVTTTDSGLQYVDVVEGDGATPQRGQTVVVHYTGTLEDGSKFDSSRDRNQPFQFKVGVGQVIKGWDEGVGS
MKVGGRRKLIIPSDLGYGSRGAGGVIPPNATLIFDVELLRIAN

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Cytoplasm And Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI17149836, Length=106, Percent_Identity=61.3207547169811, Blast_Score=137, Evalue=7e-33,
Organism=Homo sapiens, GI4503725, Length=106, Percent_Identity=61.3207547169811, Blast_Score=137, Evalue=7e-33,
Organism=Homo sapiens, GI4758380, Length=106, Percent_Identity=57.5471698113208, Blast_Score=129, Evalue=1e-30,
Organism=Homo sapiens, GI206725530, Length=90, Percent_Identity=60, Blast_Score=115, Evalue=2e-26,
Organism=Homo sapiens, GI17149844, Length=90, Percent_Identity=60, Blast_Score=115, Evalue=2e-26,
Organism=Homo sapiens, GI17149842, Length=90, Percent_Identity=60, Blast_Score=115, Evalue=2e-26,
Organism=Homo sapiens, GI224809329, Length=133, Percent_Identity=45.8646616541353, Blast_Score=106, Evalue=1e-23,
Organism=Homo sapiens, GI224809327, Length=133, Percent_Identity=45.8646616541353, Blast_Score=106, Evalue=1e-23,
Organism=Homo sapiens, GI4758384, Length=133, Percent_Identity=45.8646616541353, Blast_Score=106, Evalue=1e-23,
Organism=Homo sapiens, GI224809331, Length=133, Percent_Identity=45.8646616541353, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI192448443, Length=92, Percent_Identity=56.5217391304348, Blast_Score=100, Evalue=8e-22,
Organism=Homo sapiens, GI4503729, Length=108, Percent_Identity=48.1481481481481, Blast_Score=98, Evalue=4e-21,
Organism=Homo sapiens, GI8923659, Length=93, Percent_Identity=51.6129032258064, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI33469985, Length=94, Percent_Identity=50, Blast_Score=89, Evalue=2e-18,
Organism=Homo sapiens, GI4503727, Length=134, Percent_Identity=38.8059701492537, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI206725547, Length=123, Percent_Identity=40.650406504065, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI31317231, Length=124, Percent_Identity=41.1290322580645, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI17149839, Length=66, Percent_Identity=54.5454545454545, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI7706131, Length=86, Percent_Identity=43.0232558139535, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI150010552, Length=105, Percent_Identity=37.1428571428571, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI87082390, Length=146, Percent_Identity=44.5205479452055, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1789745, Length=203, Percent_Identity=35.9605911330049, Blast_Score=96, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71993519, Length=98, Percent_Identity=62.2448979591837, Blast_Score=124, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17540882, Length=117, Percent_Identity=48.7179487179487, Blast_Score=109, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI17561782, Length=99, Percent_Identity=54.5454545454545, Blast_Score=101, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17561778, Length=110, Percent_Identity=45.4545454545455, Blast_Score=87, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17506169, Length=141, Percent_Identity=36.8794326241135, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71993555, Length=76, Percent_Identity=52.6315789473684, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17506167, Length=141, Percent_Identity=36.8794326241135, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17561780, Length=135, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324194, Length=100, Percent_Identity=59, Blast_Score=124, Evalue=8e-30,
Organism=Saccharomyces cerevisiae, GI6320727, Length=91, Percent_Identity=59.3406593406593, Blast_Score=110, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6323566, Length=129, Percent_Identity=39.5348837209302, Blast_Score=91, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6323482, Length=100, Percent_Identity=44, Blast_Score=86, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24655568, Length=106, Percent_Identity=64.1509433962264, Blast_Score=145, Evalue=2e-35,
Organism=Drosophila melanogaster, GI281363946, Length=93, Percent_Identity=63.4408602150538, Blast_Score=129, Evalue=1e-30,
Organism=Drosophila melanogaster, GI17352457, Length=93, Percent_Identity=63.4408602150538, Blast_Score=129, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24583150, Length=96, Percent_Identity=52.0833333333333, Blast_Score=103, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24647110, Length=106, Percent_Identity=46.2264150943396, Blast_Score=97, Evalue=6e-21,
Organism=Drosophila melanogaster, GI21356629, Length=89, Percent_Identity=58.4269662921348, Blast_Score=91, Evalue=6e-19,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 21599; Mature: 21599

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METKPLQFFLRVKLGGLILRGIIISLGIAIVCGLVLIISQIIGSGKDVVASQNTPDTIGS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCC
TEIQEQVAEGTILNPTITMAENIMAQDDEKVTTTDSGLQYVDVVEGDGATPQRGQTVVVH
HHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEECCCCCEEEEEEECCCCCCCCCCEEEEE
YTGTLEDGSKFDSSRDRNQPFQFKVGVGQVIKGWDEGVGSMKVGGRRKLIIPSDLGYGSR
EECCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHCCCCCEEECCCEEEEEECCCCCCCC
GAGGVIPPNATLIFDVELLRIAN
CCCCCCCCCCEEEEEEEEEEECC
>Mature Secondary Structure
METKPLQFFLRVKLGGLILRGIIISLGIAIVCGLVLIISQIIGSGKDVVASQNTPDTIGS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCC
TEIQEQVAEGTILNPTITMAENIMAQDDEKVTTTDSGLQYVDVVEGDGATPQRGQTVVVH
HHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEECCCCCEEEEEEECCCCCCCCCCEEEEE
YTGTLEDGSKFDSSRDRNQPFQFKVGVGQVIKGWDEGVGSMKVGGRRKLIIPSDLGYGSR
EECCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHCCCCCEEECCCEEEEEECCCCCCCC
GAGGVIPPNATLIFDVELLRIAN
CCCCCCCCCCEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]