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The map label for this gene is speA [H]

Identifier: 113474916

GI number: 113474916

Start: 1798654

End: 1800735

Strand: Direct

Name: speA [H]

Synonym: Tery_1142

Alternate gene names: 113474916

Gene position: 1798654-1800735 (Clockwise)

Preceding gene: 113474914

Following gene: 113474918

Centisome position: 23.21

GC content: 31.03

Gene sequence:

>2082_bases
ATGGATTTACACTCAACTATAAATGAAAATTCTTCTCAGATTTCAAACAATACATTACTAACTAATATTTCTCAAACAGA
TCAAACAGAAATTAATGATATCAAGTCTGAACAAAAAAAATTATGGAGAATTGAAGATAGTGAGAAGCTATATAAAATAC
TTGGTTGGGGCCATCCTTATTTTTCCATTAATTCTGTTGGTCATGTAACAGTTTCTCCAAAGGGTGATTTAGGAGGTTCT
TTAGACTTATATGAACTTGTTGAGTCTATTAAACAAAGAAATATAGGGCTGCCATTAATTATTAGATTTTCAGATATTCT
TGAAGATAGAATTGAAAGGTTAAATGCTTGTTTTTCTAAAGCGATCGCTCGTTATAAGTATAAGAATATATATCGAGGTG
TATTTCCTGTAAAGTGTAATCAAAATAGTCATTTAGTAGAGGAAGTAGTTAAATTTGGCAAACCTCATAAATTTGGTCTA
GAAGCAGGTTCAAAACCAGAATTATTAATTGCTATAGCTACTTTGAATACAACGGACGGACTAATAATTTGTAATGGCTA
TAAAGACAGAGAATATATTGAGACAGCAATACTAGCTCAAAGATTAGGAAAAATACCAATAATTGTTATTGAACAAGTAG
AAGAAGTACAGTTAGTGATAGAAGCTAGTCGAAAACTAAATATTAAACCTGTAGTAGGAATTCGGGTAAAACTAAGTACT
AAAGGTATGGGTCGTTGGGCAGGAACTACAGGCGATCGCGCAAAATTCGGATTGAATATTCCTGAAATAATTAAAGTTGT
GAATCAGTTAAAAAGTACGGGTATTTTAGATTCTTTACAACTCTTACATTTTCATATTGGCTCTCAAATTTCTTCAATTA
GTGTAATTAAAGATGCTATTAGAGAAGCAAGTCAAATTTATGTAGAATTAGCTCAACTAGGAGCGAATATGAAATATTTA
GATGTAGGGGGTGGTTTAGCAGTTGATTATGATGGTTCTAAAAGCAATTTTTATGCTTCTAAAAATTATGATATGCAGAA
CTATGCTAATGATATTGTGGCAGAAGTTAAAGAAGCTTGTGAAGAGAAAAATATATTACCTCCAATATTAATTAGTGAAA
GTGGTAGAGCAGTCGCATCCCATCAATCAGTTCTAGTTTTTGATGTATTAGGAGTTAGTCAAATTCCGAAAGAAGAACCA
CCAGTTATTGGCAAAGGCGAACATTTAATTTTGCAAAACCTTTATGAAACGTATCAATCTATTAACAAAGATAATTATCA
GGAAGCATATCATGACGCAATTCAATTCAAAGAAGAATCTATTAGTATATTTAATTTTGGATATCTTAGTATTAGTGAAC
GAGCAAAAGTAGAGCAACTATATTGGGGATGTTTGAGAAAAATTCAAGAAATACTAAAAAGCTCTGAATATATTCCAAAT
GATCTGGAAGAACTAGAGAAAGTCATGGCATCTATTTACTATATTAATCTTTCTGTTTTTCAATCTGCTCCTGATAGTTG
GGCAATTAATCAATTATTTCCAATTATGCCTATACATAGATTAGATGAAGAACCTACTGAAAGAGTTATATTAGCCGACC
TTACCTGCGATAGTGATGGAAAAATTGATCGATTTATTGATTTGCGAGATATAAAATCATTACTAGAATTACACCCTCTT
CAAGTTAGTAATAAATCTTCCCAATATTCTCCTATTCAAAAACTAGAAAATTCTACTACAGAAATTATTTCTGTTTTTGA
ACCTTACTATTTGGCAATGTTTCTTGGAGGTGCATACCAAGAAATAATGGGTAATCTCCATAATTTGTTTGGTGATGTCA
ATGTTGTACATATTAAATTAAATCCTTCTGGCTACAAAATTGAACACGTTGTTAAAGGTGACACAATGACAGAAGTATTG
AATTATGTTCAGTATAATTCTGATGATCTAGTGGAAAATATTCGCTGTCAAACTGAGCAAGCTTTACAAGAAGAAAAAAT
TACCCTTAAAGAATCACGAATGCTGCTACAAAATTATGAGAGTAGTCTCAGTAGTTACACTTATTTAAGTTTAAGTAACT
AA

Upstream 100 bases:

>100_bases
AGTTTAGGCTACAGTATTATAATTTTTTTGATAACTTTTATAGCTATACTTATTAAGTTAAAATTATTTCAAATTTAGTC
TATTAAAATTAAAATATAAA

Downstream 100 bases:

>100_bases
CAAAAAATTCAGTAGCTATAAATGATATTAAAGCTATTTATAATGGCTATTGACTAATACCTAATTCAATGATTTTAGAG
TTAATTAGCAAACCCTAATT

Product: arginine decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 693; Mature: 693

Protein sequence:

>693_residues
MDLHSTINENSSQISNNTLLTNISQTDQTEINDIKSEQKKLWRIEDSEKLYKILGWGHPYFSINSVGHVTVSPKGDLGGS
LDLYELVESIKQRNIGLPLIIRFSDILEDRIERLNACFSKAIARYKYKNIYRGVFPVKCNQNSHLVEEVVKFGKPHKFGL
EAGSKPELLIAIATLNTTDGLIICNGYKDREYIETAILAQRLGKIPIIVIEQVEEVQLVIEASRKLNIKPVVGIRVKLST
KGMGRWAGTTGDRAKFGLNIPEIIKVVNQLKSTGILDSLQLLHFHIGSQISSISVIKDAIREASQIYVELAQLGANMKYL
DVGGGLAVDYDGSKSNFYASKNYDMQNYANDIVAEVKEACEEKNILPPILISESGRAVASHQSVLVFDVLGVSQIPKEEP
PVIGKGEHLILQNLYETYQSINKDNYQEAYHDAIQFKEESISIFNFGYLSISERAKVEQLYWGCLRKIQEILKSSEYIPN
DLEELEKVMASIYYINLSVFQSAPDSWAINQLFPIMPIHRLDEEPTERVILADLTCDSDGKIDRFIDLRDIKSLLELHPL
QVSNKSSQYSPIQKLENSTTEIISVFEPYYLAMFLGGAYQEIMGNLHNLFGDVNVVHIKLNPSGYKIEHVVKGDTMTEVL
NYVQYNSDDLVENIRCQTEQALQEEKITLKESRMLLQNYESSLSSYTYLSLSN

Sequences:

>Translated_693_residues
MDLHSTINENSSQISNNTLLTNISQTDQTEINDIKSEQKKLWRIEDSEKLYKILGWGHPYFSINSVGHVTVSPKGDLGGS
LDLYELVESIKQRNIGLPLIIRFSDILEDRIERLNACFSKAIARYKYKNIYRGVFPVKCNQNSHLVEEVVKFGKPHKFGL
EAGSKPELLIAIATLNTTDGLIICNGYKDREYIETAILAQRLGKIPIIVIEQVEEVQLVIEASRKLNIKPVVGIRVKLST
KGMGRWAGTTGDRAKFGLNIPEIIKVVNQLKSTGILDSLQLLHFHIGSQISSISVIKDAIREASQIYVELAQLGANMKYL
DVGGGLAVDYDGSKSNFYASKNYDMQNYANDIVAEVKEACEEKNILPPILISESGRAVASHQSVLVFDVLGVSQIPKEEP
PVIGKGEHLILQNLYETYQSINKDNYQEAYHDAIQFKEESISIFNFGYLSISERAKVEQLYWGCLRKIQEILKSSEYIPN
DLEELEKVMASIYYINLSVFQSAPDSWAINQLFPIMPIHRLDEEPTERVILADLTCDSDGKIDRFIDLRDIKSLLELHPL
QVSNKSSQYSPIQKLENSTTEIISVFEPYYLAMFLGGAYQEIMGNLHNLFGDVNVVHIKLNPSGYKIEHVVKGDTMTEVL
NYVQYNSDDLVENIRCQTEQALQEEKITLKESRMLLQNYESSLSSYTYLSLSN
>Mature_693_residues
MDLHSTINENSSQISNNTLLTNISQTDQTEINDIKSEQKKLWRIEDSEKLYKILGWGHPYFSINSVGHVTVSPKGDLGGS
LDLYELVESIKQRNIGLPLIIRFSDILEDRIERLNACFSKAIARYKYKNIYRGVFPVKCNQNSHLVEEVVKFGKPHKFGL
EAGSKPELLIAIATLNTTDGLIICNGYKDREYIETAILAQRLGKIPIIVIEQVEEVQLVIEASRKLNIKPVVGIRVKLST
KGMGRWAGTTGDRAKFGLNIPEIIKVVNQLKSTGILDSLQLLHFHIGSQISSISVIKDAIREASQIYVELAQLGANMKYL
DVGGGLAVDYDGSKSNFYASKNYDMQNYANDIVAEVKEACEEKNILPPILISESGRAVASHQSVLVFDVLGVSQIPKEEP
PVIGKGEHLILQNLYETYQSINKDNYQEAYHDAIQFKEESISIFNFGYLSISERAKVEQLYWGCLRKIQEILKSSEYIPN
DLEELEKVMASIYYINLSVFQSAPDSWAINQLFPIMPIHRLDEEPTERVILADLTCDSDGKIDRFIDLRDIKSLLELHPL
QVSNKSSQYSPIQKLENSTTEIISVFEPYYLAMFLGGAYQEIMGNLHNLFGDVNVVHIKLNPSGYKIEHVVKGDTMTEVL
NYVQYNSDDLVENIRCQTEQALQEEKITLKESRMLLQNYESSLSSYTYLSLSN

Specific function: Catalyzes the biosynthesis of agmatine from arginine [H]

COG id: COG1166

COG function: function code E; Arginine decarboxylase (spermidine biosynthesis)

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789307, Length=649, Percent_Identity=37.442218798151, Blast_Score=468, Evalue=1e-133,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002985
- InterPro:   IPR022643
- InterPro:   IPR022657
- InterPro:   IPR022644
- InterPro:   IPR022653
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 78331; Mature: 78331

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00878 ODR_DC_2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLHSTINENSSQISNNTLLTNISQTDQTEINDIKSEQKKLWRIEDSEKLYKILGWGHPY
CCCCCCCCCCCHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCC
FSINSVGHVTVSPKGDLGGSLDLYELVESIKQRNIGLPLIIRFSDILEDRIERLNACFSK
EEECCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHH
AIARYKYKNIYRGVFPVKCNQNSHLVEEVVKFGKPHKFGLEAGSKPELLIAIATLNTTDG
HHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCEECCCCCCCCCEEEEEEEECCCCC
LIICNGYKDREYIETAILAQRLGKIPIIVIEQVEEVQLVIEASRKLNIKPVVGIRVKLST
EEEECCCCCHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHCCCCCCEEEEEEEEEEC
KGMGRWAGTTGDRAKFGLNIPEIIKVVNQLKSTGILDSLQLLHFHIGSQISSISVIKDAI
CCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHH
REASQIYVELAQLGANMKYLDVGGGLAVDYDGSKSNFYASKNYDMQNYANDIVAEVKEAC
HHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHH
EEKNILPPILISESGRAVASHQSVLVFDVLGVSQIPKEEPPVIGKGEHLILQNLYETYQS
HHCCCCCCEEECCCCCEECCCCCEEEEEECCHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
INKDNYQEAYHDAIQFKEESISIFNFGYLSISERAKVEQLYWGCLRKIQEILKSSEYIPN
CCCCHHHHHHHHHHHHHHCCEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DLEELEKVMASIYYINLSVFQSAPDSWAINQLFPIMPIHRLDEEPTERVILADLTCDSDG
HHHHHHHHHHHHHHEEEHHHHCCCCCCCHHHHCCCCCHHHCCCCCCCEEEEEEEECCCCC
KIDRFIDLRDIKSLLELHPLQVSNKSSQYSPIQKLENSTTEIISVFEPYYLAMFLGGAYQ
CHHHEEEHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHCHHHH
EIMGNLHNLFGDVNVVHIKLNPSGYKIEHVVKGDTMTEVLNYVQYNSDDLVENIRCQTEQ
HHHHHHHHHHCCCEEEEEEECCCCEEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHH
ALQEEKITLKESRMLLQNYESSLSSYTYLSLSN
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECC
>Mature Secondary Structure
MDLHSTINENSSQISNNTLLTNISQTDQTEINDIKSEQKKLWRIEDSEKLYKILGWGHPY
CCCCCCCCCCCHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCC
FSINSVGHVTVSPKGDLGGSLDLYELVESIKQRNIGLPLIIRFSDILEDRIERLNACFSK
EEECCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHH
AIARYKYKNIYRGVFPVKCNQNSHLVEEVVKFGKPHKFGLEAGSKPELLIAIATLNTTDG
HHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCEECCCCCCCCCEEEEEEEECCCCC
LIICNGYKDREYIETAILAQRLGKIPIIVIEQVEEVQLVIEASRKLNIKPVVGIRVKLST
EEEECCCCCHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHCCCCCCEEEEEEEEEEC
KGMGRWAGTTGDRAKFGLNIPEIIKVVNQLKSTGILDSLQLLHFHIGSQISSISVIKDAI
CCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHH
REASQIYVELAQLGANMKYLDVGGGLAVDYDGSKSNFYASKNYDMQNYANDIVAEVKEAC
HHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHH
EEKNILPPILISESGRAVASHQSVLVFDVLGVSQIPKEEPPVIGKGEHLILQNLYETYQS
HHCCCCCCEEECCCCCEECCCCCEEEEEECCHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
INKDNYQEAYHDAIQFKEESISIFNFGYLSISERAKVEQLYWGCLRKIQEILKSSEYIPN
CCCCHHHHHHHHHHHHHHCCEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DLEELEKVMASIYYINLSVFQSAPDSWAINQLFPIMPIHRLDEEPTERVILADLTCDSDG
HHHHHHHHHHHHHHEEEHHHHCCCCCCCHHHHCCCCCHHHCCCCCCCEEEEEEEECCCCC
KIDRFIDLRDIKSLLELHPLQVSNKSSQYSPIQKLENSTTEIISVFEPYYLAMFLGGAYQ
CHHHEEEHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHCHHHH
EIMGNLHNLFGDVNVVHIKLNPSGYKIEHVVKGDTMTEVLNYVQYNSDDLVENIRCQTEQ
HHHHHHHHHHCCCEEEEEEECCCCEEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHH
ALQEEKITLKESRMLLQNYESSLSSYTYLSLSN
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]