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The map label for this gene is ureC

Identifier: 113474593

GI number: 113474593

Start: 1210324

End: 1212036

Strand: Direct

Name: ureC

Synonym: Tery_0752

Alternate gene names: 113474593

Gene position: 1210324-1212036 (Clockwise)

Preceding gene: 113474592

Following gene: 113474594

Centisome position: 15.62

GC content: 40.22

Gene sequence:

>1713_bases
ATGAGTTATCGTATGAATAGACGGACCTATGCCGAGACCTTTGGTCCAACAGTAGGCGATCGCGTTCGTTTGGCAGATAC
AGAATTATTTATTCAAGTTGAAAAAGATTACACGACCTATGGTGATGAAGTCAAGTTTGGTGGTGGTAAAGTAATTCGTG
ATGGCATGGGACAATCTCCCATATCCCGTGAAGGTGGTGCGGTAGATTTAGTAATTACCAATGCCCTAATTTTAGATTGG
TGGGGTGTGGTCAAAGCGGATATTGGAATTAAAGACGGCAAAATTCATAAAATAGGTAAAGCAGGTAATCCTTATATTCA
AGATCGGGTAGATATTATCATTGGTCCATCTACTGAAATAATTGCCGGAGAAGGACATATTATCACGGCCGGGGGAATAG
ATAGTCATATTCACTTTATTTGCCCTCAACAAATAGAAATAGCGATCGCTTCTGGGATAACAACAATGATAGGAGGTGGC
ACAGGTCCGGCCACGGGTACTAATGCTACAACCTGTACTCCTGGTCAGTGGAATATTTGGATGATGCTGCAAGCTGCCGA
TGCTTTTCCAATGAATTTGGGTTTTTTGGGAAAGGGAAATAGTGCCAAACCAGAAGGGTTAATAGAACAAATTAAAGCTG
GAGCCATGGGTTTAAAACTTCATGAAGACTGGGGAACAACTCCTGCCGCCATAGATACTTGTTTAAGTGTTGCCGATGAA
TATGACGTACAAGTAGCTATCCATACAGATACCCTTAATGAAGCAGGTTTTGTTGAAAATACGATCGCTGCCTTTAAAGA
TCGAGTAATTCATACCTATCATACTGAAGGTGCGGGAGGTGGACATGCACCAGACATTATTAAAGTTTGTGCCCTCAAAA
ACGTATTACCTTCTTCAACTAATCCGACTCGTCCTTTTACAGTCAATACTTTAGAAGAACATCTTGATATGTTAATGGTG
TGTCACCACCTTGATAAAAACATTCCTGAAGATGTAGCTTTTGCTGAATCTAGAATACGTAAAGAAACTATTGCTGCAGA
AGATATTCTGCATGATTTAGGAGCATTTAGCGCTATTGCGTCTGATTCTCAAGCAATGGGTAGAGTGGGAGAAGTTATTA
TTCGTACTTGGCAAACTGCTCACAAAATGAAAGTACAAAGAGGTATTTTAGCTTCTGAGAAAAAGGAAGTAGCAGATAAT
TTTCGTGCTAAACGCTACATTGCTAAATATACTATAAATCCGGCAATTATGCACGGTATTGCTGATTATGTTGGTTCTAT
TGAAGCCGGTAAACTAGCGGATATTTGCCTTTGGAAACCTGCTATGTTTGGGGTCAAGCCCGAAATAGTTATTAAAGGTG
GTGCGATCGCTTGGGCACAAATGGGGGACCCCAATGCTAGTATTCCGACACCCCAACCTGTATATATGCGTCCCATGTTT
GGTAGCTTTGGTGGTGCAACTTCCAGTACTTCTTTAACTTTCGTCTCTCAAGAGGCATTAGACGCTGAGATACCTAAAAA
AATCAATTTAAAAACCCCTGCTGTAGCTGTGAGTAATACACGAAATATTAGCAAGGCAGACATGAAACTAAATGAAGCTA
CACCTAAAATAGAAGTAAACCCTGAAACTTATGAAGTGAGAGCAGATGGTGAACTATTAACTTGTGAACCTGCCTATGTT
TTACCAATGACCCAACGTTATTTTTTATTTTAA

Upstream 100 bases:

>100_bases
CAACAATAAATATCTTTATTGAACAAGCATTTAATAGTAATCTTTGATCATGGAAACATTTTTTATTTAATTAAAACTTT
ATCAAGTAGGAATTCAAGTT

Downstream 100 bases:

>100_bases
ACAAAACTAATCTTTCTATGATTCAGTAAGTATTTATATTTAAGATCTCCCTGAAAATTTGACTCCTGAGCAGATAGACT
TACCCAAACTCCTAGATAAT

Product: urease subunit alpha

Products: NA

Alternate protein names: Urea amidohydrolase subunit alpha

Number of amino acids: Translated: 570; Mature: 569

Protein sequence:

>570_residues
MSYRMNRRTYAETFGPTVGDRVRLADTELFIQVEKDYTTYGDEVKFGGGKVIRDGMGQSPISREGGAVDLVITNALILDW
WGVVKADIGIKDGKIHKIGKAGNPYIQDRVDIIIGPSTEIIAGEGHIITAGGIDSHIHFICPQQIEIAIASGITTMIGGG
TGPATGTNATTCTPGQWNIWMMLQAADAFPMNLGFLGKGNSAKPEGLIEQIKAGAMGLKLHEDWGTTPAAIDTCLSVADE
YDVQVAIHTDTLNEAGFVENTIAAFKDRVIHTYHTEGAGGGHAPDIIKVCALKNVLPSSTNPTRPFTVNTLEEHLDMLMV
CHHLDKNIPEDVAFAESRIRKETIAAEDILHDLGAFSAIASDSQAMGRVGEVIIRTWQTAHKMKVQRGILASEKKEVADN
FRAKRYIAKYTINPAIMHGIADYVGSIEAGKLADICLWKPAMFGVKPEIVIKGGAIAWAQMGDPNASIPTPQPVYMRPMF
GSFGGATSSTSLTFVSQEALDAEIPKKINLKTPAVAVSNTRNISKADMKLNEATPKIEVNPETYEVRADGELLTCEPAYV
LPMTQRYFLF

Sequences:

>Translated_570_residues
MSYRMNRRTYAETFGPTVGDRVRLADTELFIQVEKDYTTYGDEVKFGGGKVIRDGMGQSPISREGGAVDLVITNALILDW
WGVVKADIGIKDGKIHKIGKAGNPYIQDRVDIIIGPSTEIIAGEGHIITAGGIDSHIHFICPQQIEIAIASGITTMIGGG
TGPATGTNATTCTPGQWNIWMMLQAADAFPMNLGFLGKGNSAKPEGLIEQIKAGAMGLKLHEDWGTTPAAIDTCLSVADE
YDVQVAIHTDTLNEAGFVENTIAAFKDRVIHTYHTEGAGGGHAPDIIKVCALKNVLPSSTNPTRPFTVNTLEEHLDMLMV
CHHLDKNIPEDVAFAESRIRKETIAAEDILHDLGAFSAIASDSQAMGRVGEVIIRTWQTAHKMKVQRGILASEKKEVADN
FRAKRYIAKYTINPAIMHGIADYVGSIEAGKLADICLWKPAMFGVKPEIVIKGGAIAWAQMGDPNASIPTPQPVYMRPMF
GSFGGATSSTSLTFVSQEALDAEIPKKINLKTPAVAVSNTRNISKADMKLNEATPKIEVNPETYEVRADGELLTCEPAYV
LPMTQRYFLF
>Mature_569_residues
SYRMNRRTYAETFGPTVGDRVRLADTELFIQVEKDYTTYGDEVKFGGGKVIRDGMGQSPISREGGAVDLVITNALILDWW
GVVKADIGIKDGKIHKIGKAGNPYIQDRVDIIIGPSTEIIAGEGHIITAGGIDSHIHFICPQQIEIAIASGITTMIGGGT
GPATGTNATTCTPGQWNIWMMLQAADAFPMNLGFLGKGNSAKPEGLIEQIKAGAMGLKLHEDWGTTPAAIDTCLSVADEY
DVQVAIHTDTLNEAGFVENTIAAFKDRVIHTYHTEGAGGGHAPDIIKVCALKNVLPSSTNPTRPFTVNTLEEHLDMLMVC
HHLDKNIPEDVAFAESRIRKETIAAEDILHDLGAFSAIASDSQAMGRVGEVIIRTWQTAHKMKVQRGILASEKKEVADNF
RAKRYIAKYTINPAIMHGIADYVGSIEAGKLADICLWKPAMFGVKPEIVIKGGAIAWAQMGDPNASIPTPQPVYMRPMFG
SFGGATSSTSLTFVSQEALDAEIPKKINLKTPAVAVSNTRNISKADMKLNEATPKIEVNPETYEVRADGELLTCEPAYVL
PMTQRYFLF

Specific function: Unknown

COG id: COG0804

COG function: function code E; Urea amidohydrolase (urease) alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 urease domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): URE1_TRIEI (Q117Z3)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_720654.1
- ProteinModelPortal:   Q117Z3
- SMR:   Q117Z3
- STRING:   Q117Z3
- GeneID:   4242484
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_0752
- NMPDR:   fig|203124.1.peg.712
- eggNOG:   COG0804
- HOGENOM:   HBG357507
- OMA:   TIHAFHT
- ProtClustDB:   PRK13207
- BioCyc:   TERY203124:TERY_0752-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01953
- InterPro:   IPR006680
- InterPro:   IPR011059
- InterPro:   IPR011612
- InterPro:   IPR005848
- InterPro:   IPR017951
- InterPro:   IPR017950
- PRINTS:   PR01752
- TIGRFAMs:   TIGR01792

Pfam domain/function: PF01979 Amidohydro_1; PF00449 Urease_alpha; SSF51338 Metalo_hydrolase

EC number: =3.5.1.5

Molecular weight: Translated: 61714; Mature: 61583

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS01120 UREASE_1; PS00145 UREASE_2; PS51368 UREASE_3

Important sites: ACT_SITE 322-322 BINDING 221-221

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYRMNRRTYAETFGPTVGDRVRLADTELFIQVEKDYTTYGDEVKFGGGKVIRDGMGQSP
CCCCCCCCHHHHHCCCCCCCEEEEECEEEEEEEECCCCCCCCEEEECCCEEEECCCCCCC
ISREGGAVDLVITNALILDWWGVVKADIGIKDGKIHKIGKAGNPYIQDRVDIIIGPSTEI
CCCCCCEEEEEEECCHHHHHHHHEEECCCCCCCCEEECCCCCCCCCCCCEEEEECCCCEE
IAGEGHIITAGGIDSHIHFICPQQIEIAIASGITTMIGGGTGPATGTNATTCTPGQWNIW
EECCCCEEEECCCCCCEEEECCCCEEEEEECCCCEEECCCCCCCCCCCCCEECCCCCEEE
MMLQAADAFPMNLGFLGKGNSAKPEGLIEQIKAGAMGLKLHEDWGTTPAAIDTCLSVADE
EEEEECCCCCCCEEEECCCCCCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHCC
YDVQVAIHTDTLNEAGFVENTIAAFKDRVIHTYHTEGAGGGHAPDIIKVCALKNVLPSST
CEEEEEEEECCCCCCCCHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCC
NPTRPFTVNTLEEHLDMLMVCHHLDKNIPEDVAFAESRIRKETIAAEDILHDLGAFSAIA
CCCCCEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SDSQAMGRVGEVIIRTWQTAHKMKVQRGILASEKKEVADNFRAKRYIAKYTINPAIMHGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHH
ADYVGSIEAGKLADICLWKPAMFGVKPEIVIKGGAIAWAQMGDPNASIPTPQPVYMRPMF
HHHHCCCCCCCCCCEEEECHHHCCCCCEEEEECCEEEEEECCCCCCCCCCCCCEEECCCC
GSFGGATSSTSLTFVSQEALDAEIPKKINLKTPAVAVSNTRNISKADMKLNEATPKIEVN
CCCCCCCCCCEEEEEEHHHHCCCCCCCCCCCCCEEEECCCCCCCHHHCEECCCCCEEEEC
PETYEVRADGELLTCEPAYVLPMTQRYFLF
CCEEEEEECCCEEEECCCEEECCCCHHHCC
>Mature Secondary Structure 
SYRMNRRTYAETFGPTVGDRVRLADTELFIQVEKDYTTYGDEVKFGGGKVIRDGMGQSP
CCCCCCCHHHHHCCCCCCCEEEEECEEEEEEEECCCCCCCCEEEECCCEEEECCCCCCC
ISREGGAVDLVITNALILDWWGVVKADIGIKDGKIHKIGKAGNPYIQDRVDIIIGPSTEI
CCCCCCEEEEEEECCHHHHHHHHEEECCCCCCCCEEECCCCCCCCCCCCEEEEECCCCEE
IAGEGHIITAGGIDSHIHFICPQQIEIAIASGITTMIGGGTGPATGTNATTCTPGQWNIW
EECCCCEEEECCCCCCEEEECCCCEEEEEECCCCEEECCCCCCCCCCCCCEECCCCCEEE
MMLQAADAFPMNLGFLGKGNSAKPEGLIEQIKAGAMGLKLHEDWGTTPAAIDTCLSVADE
EEEEECCCCCCCEEEECCCCCCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHCC
YDVQVAIHTDTLNEAGFVENTIAAFKDRVIHTYHTEGAGGGHAPDIIKVCALKNVLPSST
CEEEEEEEECCCCCCCCHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCC
NPTRPFTVNTLEEHLDMLMVCHHLDKNIPEDVAFAESRIRKETIAAEDILHDLGAFSAIA
CCCCCEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SDSQAMGRVGEVIIRTWQTAHKMKVQRGILASEKKEVADNFRAKRYIAKYTINPAIMHGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHH
ADYVGSIEAGKLADICLWKPAMFGVKPEIVIKGGAIAWAQMGDPNASIPTPQPVYMRPMF
HHHHCCCCCCCCCCEEEECHHHCCCCCEEEEECCEEEEEECCCCCCCCCCCCCEEECCCC
GSFGGATSSTSLTFVSQEALDAEIPKKINLKTPAVAVSNTRNISKADMKLNEATPKIEVN
CCCCCCCCCCEEEEEEHHHHCCCCCCCCCCCCCEEEECCCCCCCHHHCEECCCCCEEEEC
PETYEVRADGELLTCEPAYVLPMTQRYFLF
CCEEEEEECCCEEEECCCEEECCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA