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The map label for this gene is fbp

Identifier: 113474531

GI number: 113474531

Start: 1114288

End: 1115352

Strand: Direct

Name: fbp

Synonym: Tery_0682

Alternate gene names: 113474531

Gene position: 1114288-1115352 (Clockwise)

Preceding gene: 113474530

Following gene: 113474532

Centisome position: 14.38

GC content: 40.09

Gene sequence:

>1065_bases
ATGGTAAATACCCAAGCTCGGGAAGACCTCCACATTCGTCTGGAGGAAACACAGTTATTGGATCGTGACTGTACTACCTT
ATCACGTCATGTACTACAGCAACTTCATTTTTCACCGGATGCTCAAGATATAAGCTCCTTAATGAATAGAATAGGTTTGG
CCGGGAAGTTAATCGCTCGTCGCCTAACTCGTGCTGGGCTATTAGAAGATACTTTAGGGTTTACTGGCACAGTTAATGTC
CAGGGAGAGTCCGTCAAAAAGATGGATATCTATGCCAATGATGTATTTATCTCTGTATTTAAGCAAAGTGGCCTTGTCTG
CCGCTTGGCATCTGAAGAGATGGAAAAACCTTATTATATTCCAGAAAATTGTCCAATTGGCCGCTATACTTTGCTTTATG
ACCCTCTGGATGGTTCTTCTAATCTAGATACAAATTTAAATGTGGGATCTATATTCTCAGTTCGCCAACAAGAAGGTAAT
GATGAAAATGGTTTAGCTCAAGATTTACTTCAAAATGGACATAAACAAATTGCTGCTGGTTATATTCTATATGGACCGAG
CACAATGTTGGTATATTCAATAGGTCAAGGAGTACACGCATTTACTCTAGACCCGAGCCTAGGTGAGTTTATTCTTGTTA
ATGAGAATATTAAAATTCCAGAACATGGTCCGGTCTACAGTGTGAATGAGGGTAACTTTTGGCAGTGGGATGATAGTATG
CGGGATTATATCCGCTATGTTCATCGCCATGAGGGTTATACTGCTCGTTATGGTGGCGCATTAGTGGGAGATTTCCATAG
AATTTTATATCAAGGTGGGGTATTTTTGTACCCAGGTACAGTTAAAAAGCCAGAAGGAAAATTACGTCTGTTATATGAAT
CAGCTCCAATGGGTTATCTAGTGGAACAAGCAGGTGGGAGAGCTAGCACAGGAACTGAAGAAATATTAGATGTAGTAGCA
GATCAACTGCATCAACGGACGCCATTGATTATTGGTAGTAAGGAAGATGTGGCGCTTGTTGAGTCTTTTATTAAAGAACA
AAAACGCATTTCTAATCAAGGTTAA

Upstream 100 bases:

>100_bases
AAATAAAATAAATCTAAGAAATTCATATCTAAGAAGTAAAGTTCAAATATGAACAACTAGTCTATTGACTGGAGCTACTC
AAGATGGAGAAACTACATAT

Downstream 100 bases:

>100_bases
TAGCTTGAATTAGGTTATAGATTGAAAGTTGTTGTCAGCATAAATTGTGATTGCACATAGACTTTACTACTCTTAAGAAT
AATAGTAAATAAATTTTGAA

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MVNTQAREDLHIRLEETQLLDRDCTTLSRHVLQQLHFSPDAQDISSLMNRIGLAGKLIARRLTRAGLLEDTLGFTGTVNV
QGESVKKMDIYANDVFISVFKQSGLVCRLASEEMEKPYYIPENCPIGRYTLLYDPLDGSSNLDTNLNVGSIFSVRQQEGN
DENGLAQDLLQNGHKQIAAGYILYGPSTMLVYSIGQGVHAFTLDPSLGEFILVNENIKIPEHGPVYSVNEGNFWQWDDSM
RDYIRYVHRHEGYTARYGGALVGDFHRILYQGGVFLYPGTVKKPEGKLRLLYESAPMGYLVEQAGGRASTGTEEILDVVA
DQLHQRTPLIIGSKEDVALVESFIKEQKRISNQG

Sequences:

>Translated_354_residues
MVNTQAREDLHIRLEETQLLDRDCTTLSRHVLQQLHFSPDAQDISSLMNRIGLAGKLIARRLTRAGLLEDTLGFTGTVNV
QGESVKKMDIYANDVFISVFKQSGLVCRLASEEMEKPYYIPENCPIGRYTLLYDPLDGSSNLDTNLNVGSIFSVRQQEGN
DENGLAQDLLQNGHKQIAAGYILYGPSTMLVYSIGQGVHAFTLDPSLGEFILVNENIKIPEHGPVYSVNEGNFWQWDDSM
RDYIRYVHRHEGYTARYGGALVGDFHRILYQGGVFLYPGTVKKPEGKLRLLYESAPMGYLVEQAGGRASTGTEEILDVVA
DQLHQRTPLIIGSKEDVALVESFIKEQKRISNQG
>Mature_354_residues
MVNTQAREDLHIRLEETQLLDRDCTTLSRHVLQQLHFSPDAQDISSLMNRIGLAGKLIARRLTRAGLLEDTLGFTGTVNV
QGESVKKMDIYANDVFISVFKQSGLVCRLASEEMEKPYYIPENCPIGRYTLLYDPLDGSSNLDTNLNVGSIFSVRQQEGN
DENGLAQDLLQNGHKQIAAGYILYGPSTMLVYSIGQGVHAFTLDPSLGEFILVNENIKIPEHGPVYSVNEGNFWQWDDSM
RDYIRYVHRHEGYTARYGGALVGDFHRILYQGGVFLYPGTVKKPEGKLRLLYESAPMGYLVEQAGGRASTGTEEILDVVA
DQLHQRTPLIIGSKEDVALVESFIKEQKRISNQG

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family

Homologues:

Organism=Homo sapiens, GI22907028, Length=322, Percent_Identity=42.8571428571429, Blast_Score=253, Evalue=2e-67,
Organism=Homo sapiens, GI189083692, Length=338, Percent_Identity=42.0118343195266, Blast_Score=253, Evalue=2e-67,
Organism=Homo sapiens, GI16579888, Length=338, Percent_Identity=42.0118343195266, Blast_Score=253, Evalue=2e-67,
Organism=Escherichia coli, GI1790679, Length=328, Percent_Identity=46.0365853658537, Blast_Score=296, Evalue=2e-81,
Organism=Caenorhabditis elegans, GI17508131, Length=323, Percent_Identity=45.8204334365325, Blast_Score=278, Evalue=3e-75,
Organism=Saccharomyces cerevisiae, GI6323409, Length=333, Percent_Identity=38.7387387387387, Blast_Score=243, Evalue=4e-65,
Organism=Drosophila melanogaster, GI45550998, Length=335, Percent_Identity=42.9850746268657, Blast_Score=272, Evalue=2e-73,
Organism=Drosophila melanogaster, GI19921562, Length=335, Percent_Identity=42.9850746268657, Blast_Score=272, Evalue=3e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): F16PA_TRIEI (Q118F5)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_720592.1
- ProteinModelPortal:   Q118F5
- SMR:   Q118F5
- STRING:   Q118F5
- GeneID:   4242821
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_0682
- NMPDR:   fig|203124.1.peg.635
- eggNOG:   COG0158
- HOGENOM:   HBG731261
- OMA:   YSINEGS
- PhylomeDB:   Q118F5
- ProtClustDB:   PRK09293
- BioCyc:   TERY203124:TERY_0682-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01855
- InterPro:   IPR000146
- InterPro:   IPR020548
- PANTHER:   PTHR11556
- PRINTS:   PR00115

Pfam domain/function: PF00316 FBPase

EC number: =3.1.3.11

Molecular weight: Translated: 39588; Mature: 39588

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00124 FBPASE

Important sites: BINDING 229-229 BINDING 257-257 BINDING 287-287

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNTQAREDLHIRLEETQLLDRDCTTLSRHVLQQLHFSPDAQDISSLMNRIGLAGKLIAR
CCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCHHHHHHHH
RLTRAGLLEDTLGFTGTVNVQGESVKKMDIYANDVFISVFKQSGLVCRLASEEMEKPYYI
HHHHHCCHHHHCCCCEEEEECCCCEEEEEEEHHHHHHEEHHHCCCEEEECHHHCCCCEEC
PENCPIGRYTLLYDPLDGSSNLDTNLNVGSIFSVRQQEGNDENGLAQDLLQNGHKQIAAG
CCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEHHHCCCCCCHHHHHHHHCCCCEECCC
YILYGPSTMLVYSIGQGVHAFTLDPSLGEFILVNENIKIPEHGPVYSVNEGNFWQWDDSM
EEEECCCEEEEEECCCCCEEEEECCCCCCEEEEECCEECCCCCCEEECCCCCCEECCHHH
RDYIRYVHRHEGYTARYGGALVGDFHRILYQGGVFLYPGTVKKPEGKLRLLYESAPMGYL
HHHHHHHHHCCCCEEECCCHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEECCCCCHH
VEQAGGRASTGTEEILDVVADQLHQRTPLIIGSKEDVALVESFIKEQKRISNQG
HHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVNTQAREDLHIRLEETQLLDRDCTTLSRHVLQQLHFSPDAQDISSLMNRIGLAGKLIAR
CCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCHHHHHHHH
RLTRAGLLEDTLGFTGTVNVQGESVKKMDIYANDVFISVFKQSGLVCRLASEEMEKPYYI
HHHHHCCHHHHCCCCEEEEECCCCEEEEEEEHHHHHHEEHHHCCCEEEECHHHCCCCEEC
PENCPIGRYTLLYDPLDGSSNLDTNLNVGSIFSVRQQEGNDENGLAQDLLQNGHKQIAAG
CCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEHHHCCCCCCHHHHHHHHCCCCEECCC
YILYGPSTMLVYSIGQGVHAFTLDPSLGEFILVNENIKIPEHGPVYSVNEGNFWQWDDSM
EEEECCCEEEEEECCCCCEEEEECCCCCCEEEEECCEECCCCCCEEECCCCCCEECCHHH
RDYIRYVHRHEGYTARYGGALVGDFHRILYQGGVFLYPGTVKKPEGKLRLLYESAPMGYL
HHHHHHHHHCCCCEEECCCHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEECCCCCHH
VEQAGGRASTGTEEILDVVADQLHQRTPLIIGSKEDVALVESFIKEQKRISNQG
HHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA