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The map label for this gene is luxQ [H]

Identifier: 113474512

GI number: 113474512

Start: 1079303

End: 1082704

Strand: Direct

Name: luxQ [H]

Synonym: Tery_0661

Alternate gene names: 113474512

Gene position: 1079303-1082704 (Clockwise)

Preceding gene: 113474509

Following gene: 113474513

Centisome position: 13.93

GC content: 36.13

Gene sequence:

>3402_bases
ATGGCATTTAAATCTTTGTCCCTAAACCTGGGTAGAATATTTAGTAAGCTTTCTTTAAAAACTATTTTAATAGTACCCTA
TGTTATCCAAATTCTTGGTGCTTTTGGAGCATTAGGATATATAGCTTTTCTGAATGGGCAACAAACCGTTGATGATTTGG
GCAAAAAGCTAACTAACAAAATTAGCGATCGCATTCAACAGCACGTTTTGGGATATTTAAATCAATCTCATCAAGTTCTG
AGGATCACTAATGATGCTATAGAAAGTGCAAACTTAGACATCTATAATTTTGTCGCACTCAGGCGATACTTTTGGGAAGT
CGTAAAAGAAAAAGATTTACAGGATTATTTATTCTTTGGCAACGAAGAAGGAGAATTTATTGGCGTCGAACATTTCGCAG
AAGGAGAAATTTACCTAAAAAGTTGTAAAATCCCTACCCAAAGCCTTTGCGAAACTTATCTGCTTAATAATCAAGGTAAC
ATTAGCCAATATTTAAACAGCAAAGAGTACGACCCCCGGGATACTCCCTGGTATTTAGTAGCAAAAAAATTAGGCGAGCC
CACCTGGAGTCCAATTTTGTCCTCATTTTCTGGTCAAAATAGCTCCCTCGACATCTTCGCAGTTCAACCTATTTTTGACT
CAACAGAGAATTTATTAGGAGTTCTCTCAAACAAAACCACCCTGGTCAAACTCACAAATTTCCTCAAAAACTTATACATT
AGTCCCAACGGTCAAAGTTTCATTATCGAACGATCGGGAAACTTAATTGCTTCTTCCGAGGTTATGGAGCCTTTTGTAAT
TAAAGGAACTCAGGAAAATCGAAAAATAGAACGCCTACCCGCCACTGCTAGTGAGAATAAGATAGTAAGCATGACGACAA
AACATCTACAACAAAAGTTTAGTAGTTTTGCCGAAATTACTCACACTCACGAAATGAATTTTCCTATTGAAGAAGAATGG
TACTATGCTAGTGTTATACCAGTAATAGACGGACGAGGTATTAATTGGCTAGCAGTAGTAGTTATTCCTGAAGATGACTT
CATGGAAAAAGTCAATATGAACATTCGTACTACTATTCTATTAAGTTTTGCTGCCTTGACAATAACCGTATTATTAGGAA
TAGTCACCACTAACTGGATAACCAAGCCTATCTTACAACTTAATTCTGCTGCCAAAGAAATTTCTCAAGGAAAATGGGAA
ACCCAACTCAAAATTTATCGCGAAGATGAATTAGGGGAACTGGCCAACTCCTTTGATCAGATGGCAAGCCAGCTCAAGAA
ATCCTTTGAAACCCTAGAAGCCCAAAATAAACAACTCACAGAACTAGATCGCCTTAAAGATGAATTTCTTGCCAATACCT
CCCACGAACTCCGCACCCCACTAAATGGTATTATCGGTATTGGAGAATTTCTACTAGAAGAAAACACTAAAAATTTAAAC
TCTATAACTACCTCTAACTTAGCCATAATAGTTTCTAGTGCTCGTCGTCTCTCCAACCTCGTCAACGATATTCTCGACTT
TTCTAAAATTAGATACCACAAATTAGAATTACAAGTCAGAGCCATTGATGTTAGGATAGTCGTTGAATCAGTTATCACCC
TAAATAGAGTATTAGTTGGCAAAAACAAAAATCTGCAATTAACAAATGCTATACCGACAGACTTACCCCCCGTTTTAGCT
GATGAAAACCGTCTACAACAGATACTCTATAATTTAATTGCCAATGCTATCAAATTCACTGAATCTGGGAAAGTCGAAAT
CTCTGCTTCCCTCTACTCCCCTAAAGAAGATCAAGATGAAGCCACTGAAATTATTATCATGGTATCTGATACTGGTATCG
GTATTCCCCCTGATCAACTAGATCGTATCTTTGAATCTTTTGAACAAGGAGAAGGTTCAATTATAAGAAAATACGGCGGT
ACAGGTTTAGGTTTGGCTGTCACCAAAGAATTAGTAGAACTCCAAGGCGGTCGTATTTGGGTTGAGTCTGAAGTTGGTGT
AGGTTCCCGGTTTAACGTGACCTTACCCATATCTAATCAACTCGTACCTAATTCCTCTTTAAATTTTCCTAGTCCTACTG
TTAATAATATTCACTATCTGATCAAGAACATAGAAACAACTATCAGGAGTAAACCCCTAGGAAGTAAAATACCTAATGGT
GATTTCCACGTTTTAGTTGTTGATGATGAACCGATAAATATTCAAGTTTTAAACAATTACCTCAAAGCCAATAATTATCA
AGTTACCCAGGCATTAAGTGGAAAAGAAGCTTTGGCGGCTTTGGAGAATAATCATAATTTTGACTTAATTTTGCTAGATG
TAATGATGCCAAATATGTCTGGTTATGAGGTATGCTCTCAAATTAGAGAAAAATATCCGGCCCAAAGTTTACCTGTGTTA
ATGTTAACAGCTAAAAATCAAATTGCTGATTTAGTTATGGGTTTCCAATTTGGTGCTAATGATTATTTAACTAAACCTTT
TGCTAAAGATGAGTTATTAACCCGGATTCAAACTCATATTAAATTATCAAAAATCACTAAAGCTTACGAGCGTTTTGTTC
CCCACGAATATGTTGAGTTACTCTCAAAAGAAAGCATTATTAATGTTAAACTAGGGGATCGAGTTAGTACTAAAATGGCA
ATTTTCTTTTCTGATATTCGCTCTTTTACGACTATATCTGAGCAGATGACTTCTCAAGAAACTTTTGCTTTTGTGAATGG
TTATTTAAAGGAGGTTTGTCCAGAAATTCGCGATCGCAACGGTTTGATTATTAAATTTCTGGGAGATGGTATTATGGCAG
TATTTCCAGATGGAGCTGATGATGCATTGGAGGCAGCTATTGCTCAACTCAAAAGATTACAGGAATATAATCAGGTTCTA
TTATCTACAGGTTGGATGCCTATAAAAATTGGAATTGGTATTCATTGGGGTCACATTATGGTAGGCATAGTTGGAGAAAA
GGGTCGGATGTCAGGAGATGCATTTTCTAATAATGTGAATTTGACATCTCGTTTGGAAGGTTTGACTAAGTTTTATGGTG
TTTCTTTATTAATTTCTGAGTCAGCTTTTAACTATTTAAAAAATCCGCAGAAATATCAAATTAGGTTTTTAGACCGGGCA
TCTGTTAAGGGTATAGATGAACCGATTAATGTTTATGAAGTTCTTGATGGTGAAGTTGATGAGATACGAGAGTTAAAATT
ACAAACTCAGGTAGATTTTGCATTAGGTTTGGAGTCTTATCGTGTAGGAGAGTTAGTTGATGCTAAAGATTATTTTGAGA
AAGTATTAGCCGTTAATTATTCAGATAAAACAGCTCAACTTTATCTGGAAAGAATTGATGATTTGATGGTAACTGGTGTG
CCCAAAAATTGGAATGGGGTTTGGGCATTTACTCAGAAGTAA

Upstream 100 bases:

>100_bases
TAACTTTTAATTCAAAATGCTCCTGATGTTAACTCACTCACTGATTAACAGTTCCTAATCAACAGAGAAATATACTAACT
AAAAAAAATAATTAGCTTTC

Downstream 100 bases:

>100_bases
TGTTAAATTATAGAAATTAAACTATAAGGTTCTTAATCTGGAAAACACTAGGCAATATGCTTATAGTACAAAGATTTTAT
TATTAATTAATAATTAATTA

Product: adenylate/guanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1133; Mature: 1132

Protein sequence:

>1133_residues
MAFKSLSLNLGRIFSKLSLKTILIVPYVIQILGAFGALGYIAFLNGQQTVDDLGKKLTNKISDRIQQHVLGYLNQSHQVL
RITNDAIESANLDIYNFVALRRYFWEVVKEKDLQDYLFFGNEEGEFIGVEHFAEGEIYLKSCKIPTQSLCETYLLNNQGN
ISQYLNSKEYDPRDTPWYLVAKKLGEPTWSPILSSFSGQNSSLDIFAVQPIFDSTENLLGVLSNKTTLVKLTNFLKNLYI
SPNGQSFIIERSGNLIASSEVMEPFVIKGTQENRKIERLPATASENKIVSMTTKHLQQKFSSFAEITHTHEMNFPIEEEW
YYASVIPVIDGRGINWLAVVVIPEDDFMEKVNMNIRTTILLSFAALTITVLLGIVTTNWITKPILQLNSAAKEISQGKWE
TQLKIYREDELGELANSFDQMASQLKKSFETLEAQNKQLTELDRLKDEFLANTSHELRTPLNGIIGIGEFLLEENTKNLN
SITTSNLAIIVSSARRLSNLVNDILDFSKIRYHKLELQVRAIDVRIVVESVITLNRVLVGKNKNLQLTNAIPTDLPPVLA
DENRLQQILYNLIANAIKFTESGKVEISASLYSPKEDQDEATEIIIMVSDTGIGIPPDQLDRIFESFEQGEGSIIRKYGG
TGLGLAVTKELVELQGGRIWVESEVGVGSRFNVTLPISNQLVPNSSLNFPSPTVNNIHYLIKNIETTIRSKPLGSKIPNG
DFHVLVVDDEPINIQVLNNYLKANNYQVTQALSGKEALAALENNHNFDLILLDVMMPNMSGYEVCSQIREKYPAQSLPVL
MLTAKNQIADLVMGFQFGANDYLTKPFAKDELLTRIQTHIKLSKITKAYERFVPHEYVELLSKESIINVKLGDRVSTKMA
IFFSDIRSFTTISEQMTSQETFAFVNGYLKEVCPEIRDRNGLIIKFLGDGIMAVFPDGADDALEAAIAQLKRLQEYNQVL
LSTGWMPIKIGIGIHWGHIMVGIVGEKGRMSGDAFSNNVNLTSRLEGLTKFYGVSLLISESAFNYLKNPQKYQIRFLDRA
SVKGIDEPINVYEVLDGEVDEIRELKLQTQVDFALGLESYRVGELVDAKDYFEKVLAVNYSDKTAQLYLERIDDLMVTGV
PKNWNGVWAFTQK

Sequences:

>Translated_1133_residues
MAFKSLSLNLGRIFSKLSLKTILIVPYVIQILGAFGALGYIAFLNGQQTVDDLGKKLTNKISDRIQQHVLGYLNQSHQVL
RITNDAIESANLDIYNFVALRRYFWEVVKEKDLQDYLFFGNEEGEFIGVEHFAEGEIYLKSCKIPTQSLCETYLLNNQGN
ISQYLNSKEYDPRDTPWYLVAKKLGEPTWSPILSSFSGQNSSLDIFAVQPIFDSTENLLGVLSNKTTLVKLTNFLKNLYI
SPNGQSFIIERSGNLIASSEVMEPFVIKGTQENRKIERLPATASENKIVSMTTKHLQQKFSSFAEITHTHEMNFPIEEEW
YYASVIPVIDGRGINWLAVVVIPEDDFMEKVNMNIRTTILLSFAALTITVLLGIVTTNWITKPILQLNSAAKEISQGKWE
TQLKIYREDELGELANSFDQMASQLKKSFETLEAQNKQLTELDRLKDEFLANTSHELRTPLNGIIGIGEFLLEENTKNLN
SITTSNLAIIVSSARRLSNLVNDILDFSKIRYHKLELQVRAIDVRIVVESVITLNRVLVGKNKNLQLTNAIPTDLPPVLA
DENRLQQILYNLIANAIKFTESGKVEISASLYSPKEDQDEATEIIIMVSDTGIGIPPDQLDRIFESFEQGEGSIIRKYGG
TGLGLAVTKELVELQGGRIWVESEVGVGSRFNVTLPISNQLVPNSSLNFPSPTVNNIHYLIKNIETTIRSKPLGSKIPNG
DFHVLVVDDEPINIQVLNNYLKANNYQVTQALSGKEALAALENNHNFDLILLDVMMPNMSGYEVCSQIREKYPAQSLPVL
MLTAKNQIADLVMGFQFGANDYLTKPFAKDELLTRIQTHIKLSKITKAYERFVPHEYVELLSKESIINVKLGDRVSTKMA
IFFSDIRSFTTISEQMTSQETFAFVNGYLKEVCPEIRDRNGLIIKFLGDGIMAVFPDGADDALEAAIAQLKRLQEYNQVL
LSTGWMPIKIGIGIHWGHIMVGIVGEKGRMSGDAFSNNVNLTSRLEGLTKFYGVSLLISESAFNYLKNPQKYQIRFLDRA
SVKGIDEPINVYEVLDGEVDEIRELKLQTQVDFALGLESYRVGELVDAKDYFEKVLAVNYSDKTAQLYLERIDDLMVTGV
PKNWNGVWAFTQK
>Mature_1132_residues
AFKSLSLNLGRIFSKLSLKTILIVPYVIQILGAFGALGYIAFLNGQQTVDDLGKKLTNKISDRIQQHVLGYLNQSHQVLR
ITNDAIESANLDIYNFVALRRYFWEVVKEKDLQDYLFFGNEEGEFIGVEHFAEGEIYLKSCKIPTQSLCETYLLNNQGNI
SQYLNSKEYDPRDTPWYLVAKKLGEPTWSPILSSFSGQNSSLDIFAVQPIFDSTENLLGVLSNKTTLVKLTNFLKNLYIS
PNGQSFIIERSGNLIASSEVMEPFVIKGTQENRKIERLPATASENKIVSMTTKHLQQKFSSFAEITHTHEMNFPIEEEWY
YASVIPVIDGRGINWLAVVVIPEDDFMEKVNMNIRTTILLSFAALTITVLLGIVTTNWITKPILQLNSAAKEISQGKWET
QLKIYREDELGELANSFDQMASQLKKSFETLEAQNKQLTELDRLKDEFLANTSHELRTPLNGIIGIGEFLLEENTKNLNS
ITTSNLAIIVSSARRLSNLVNDILDFSKIRYHKLELQVRAIDVRIVVESVITLNRVLVGKNKNLQLTNAIPTDLPPVLAD
ENRLQQILYNLIANAIKFTESGKVEISASLYSPKEDQDEATEIIIMVSDTGIGIPPDQLDRIFESFEQGEGSIIRKYGGT
GLGLAVTKELVELQGGRIWVESEVGVGSRFNVTLPISNQLVPNSSLNFPSPTVNNIHYLIKNIETTIRSKPLGSKIPNGD
FHVLVVDDEPINIQVLNNYLKANNYQVTQALSGKEALAALENNHNFDLILLDVMMPNMSGYEVCSQIREKYPAQSLPVLM
LTAKNQIADLVMGFQFGANDYLTKPFAKDELLTRIQTHIKLSKITKAYERFVPHEYVELLSKESIINVKLGDRVSTKMAI
FFSDIRSFTTISEQMTSQETFAFVNGYLKEVCPEIRDRNGLIIKFLGDGIMAVFPDGADDALEAAIAQLKRLQEYNQVLL
STGWMPIKIGIGIHWGHIMVGIVGEKGRMSGDAFSNNVNLTSRLEGLTKFYGVSLLISESAFNYLKNPQKYQIRFLDRAS
VKGIDEPINVYEVLDGEVDEIRELKLQTQVDFALGLESYRVGELVDAKDYFEKVLAVNYSDKTAQLYLERIDDLMVTGVP
KNWNGVWAFTQK

Specific function: At low cell density, in absence of AI-2 (autoinducer 2), luxQ has a kinase activity and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=341, Percent_Identity=34.8973607038123, Blast_Score=181, Evalue=2e-46,
Organism=Escherichia coli, GI48994928, Length=397, Percent_Identity=33.5012594458438, Blast_Score=180, Evalue=4e-46,
Organism=Escherichia coli, GI1788713, Length=422, Percent_Identity=28.1990521327014, Blast_Score=159, Evalue=6e-40,
Organism=Escherichia coli, GI87081816, Length=462, Percent_Identity=27.9220779220779, Blast_Score=152, Evalue=1e-37,
Organism=Escherichia coli, GI145693157, Length=255, Percent_Identity=37.2549019607843, Blast_Score=142, Evalue=1e-34,
Organism=Escherichia coli, GI1788393, Length=300, Percent_Identity=30.6666666666667, Blast_Score=120, Evalue=5e-28,
Organism=Escherichia coli, GI1790436, Length=255, Percent_Identity=30.5882352941176, Blast_Score=100, Evalue=9e-22,
Organism=Escherichia coli, GI1786600, Length=241, Percent_Identity=28.6307053941909, Blast_Score=94, Evalue=4e-20,
Organism=Escherichia coli, GI1790346, Length=301, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=6e-19,
Organism=Escherichia coli, GI1788549, Length=247, Percent_Identity=27.1255060728745, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1790861, Length=337, Percent_Identity=28.7833827893175, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1786912, Length=244, Percent_Identity=28.2786885245902, Blast_Score=86, Evalue=2e-17,
Organism=Escherichia coli, GI87082128, Length=244, Percent_Identity=26.2295081967213, Blast_Score=85, Evalue=3e-17,
Organism=Escherichia coli, GI1788394, Length=121, Percent_Identity=35.5371900826446, Blast_Score=83, Evalue=1e-16,
Organism=Escherichia coli, GI1789809, Length=121, Percent_Identity=33.0578512396694, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1786783, Length=353, Percent_Identity=23.7960339943343, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1787894, Length=364, Percent_Identity=24.1758241758242, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI87082012, Length=120, Percent_Identity=31.6666666666667, Blast_Score=77, Evalue=9e-15,
Organism=Escherichia coli, GI1786599, Length=118, Percent_Identity=36.4406779661017, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI1790552, Length=118, Percent_Identity=33.8983050847458, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI1786784, Length=142, Percent_Identity=32.3943661971831, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI1787229, Length=115, Percent_Identity=31.304347826087, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI1790860, Length=77, Percent_Identity=41.5584415584416, Blast_Score=74, Evalue=6e-14,
Organism=Escherichia coli, GI1789402, Length=93, Percent_Identity=39.7849462365591, Blast_Score=71, Evalue=4e-13,
Organism=Escherichia coli, GI1790863, Length=115, Percent_Identity=29.5652173913043, Blast_Score=70, Evalue=9e-13,
Organism=Escherichia coli, GI1788905, Length=121, Percent_Identity=36.3636363636364, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1790299, Length=117, Percent_Identity=35.8974358974359, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1790437, Length=109, Percent_Identity=37.6146788990826, Blast_Score=67, Evalue=6e-12,
Organism=Escherichia coli, GI1790300, Length=235, Percent_Identity=27.6595744680851, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1788279, Length=271, Percent_Identity=25.0922509225092, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=74, Percent_Identity=47.2972972972973, Blast_Score=78, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6322000, Length=111, Percent_Identity=34.2342342342342, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 127532; Mature: 127401

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS50885 HAMP ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN ; PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFKSLSLNLGRIFSKLSLKTILIVPYVIQILGAFGALGYIAFLNGQQTVDDLGKKLTNK
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHH
ISDRIQQHVLGYLNQSHQVLRITNDAIESANLDIYNFVALRRYFWEVVKEKDLQDYLFFG
HHHHHHHHHHHHHCCCCEEEEEECHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHEEC
NEEGEFIGVEHFAEGEIYLKSCKIPTQSLCETYLLNNQGNISQYLNSKEYDPRDTPWYLV
CCCCCEEEEEEECCCCEEEEECCCCHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCHHHH
AKKLGEPTWSPILSSFSGQNSSLDIFAVQPIFDSTENLLGVLSNKTTLVKLTNFLKNLYI
HHHHCCCCHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHCEE
SPNGQSFIIERSGNLIASSEVMEPFVIKGTQENRKIERLPATASENKIVSMTTKHLQQKF
CCCCCEEEEECCCCEEECHHHCCCEEEECCCCCCHHHHCCCCCCCCEEEHHHHHHHHHHH
SSFAEITHTHEMNFPIEEEWYYASVIPVIDGRGINWLAVVVIPEDDFMEKVNMNIRTTIL
HHHHHHHHHCCCCCCCCCCEEEEEEEEEECCCCCCEEEEEEECCHHHHHHHCCCHHHHHH
LSFAALTITVLLGIVTTNWITKPILQLNSAAKEISQGKWETQLKIYREDELGELANSFDQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECHHHHHHHHHHHH
MASQLKKSFETLEAQNKQLTELDRLKDEFLANTSHELRTPLNGIIGIGEFLLEENTKNLN
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHCCCCCCH
SITTSNLAIIVSSARRLSNLVNDILDFSKIRYHKLELQVRAIDVRIVVESVITLNRVLVG
HCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEEHHHHHHHHHHHHHHEEC
KNKNLQLTNAIPTDLPPVLADENRLQQILYNLIANAIKFTESGKVEISASLYSPKEDQDE
CCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCC
ATEIIIMVSDTGIGIPPDQLDRIFESFEQGEGSIIRKYGGTGLGLAVTKELVELQGGRIW
CEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHCCCEEE
VESEVGVGSRFNVTLPISNQLVPNSSLNFPSPTVNNIHYLIKNIETTIRSKPLGSKIPNG
EEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
DFHVLVVDDEPINIQVLNNYLKANNYQVTQALSGKEALAALENNHNFDLILLDVMMPNMS
CEEEEEECCCCCEEHEEHHHHHCCCEEEEHHCCCHHHHHHHHCCCCEEEEEEEECCCCCC
GYEVCSQIREKYPAQSLPVLMLTAKNQIADLVMGFQFGANDYLTKPFAKDELLTRIQTHI
HHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
KLSKITKAYERFVPHEYVELLSKESIINVKLGDRVSTKMAIFFSDIRSFTTISEQMTSQE
HHHHHHHHHHHHCCHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TFAFVNGYLKEVCPEIRDRNGLIIKFLGDGIMAVFPDGADDALEAAIAQLKRLQEYNQVL
HHHHHHHHHHHHCHHHHCCCCEEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
LSTGWMPIKIGIGIHWGHIMVGIVGEKGRMSGDAFSNNVNLTSRLEGLTKFYGVSLLISE
HHCCCEEEEEEEEEEECEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEEH
SAFNYLKNPQKYQIRFLDRASVKGIDEPINVYEVLDGEVDEIRELKLQTQVDFALGLESY
HHHHHHCCCCEEEEEEEECCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC
RVGELVDAKDYFEKVLAVNYSDKTAQLYLERIDDLMVTGVPKNWNGVWAFTQK
CCCCCCCHHHHHHHHHEECCCCHHHHHHHHHHHHHEEECCCCCCCCEEEEECC
>Mature Secondary Structure 
AFKSLSLNLGRIFSKLSLKTILIVPYVIQILGAFGALGYIAFLNGQQTVDDLGKKLTNK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHH
ISDRIQQHVLGYLNQSHQVLRITNDAIESANLDIYNFVALRRYFWEVVKEKDLQDYLFFG
HHHHHHHHHHHHHCCCCEEEEEECHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHEEC
NEEGEFIGVEHFAEGEIYLKSCKIPTQSLCETYLLNNQGNISQYLNSKEYDPRDTPWYLV
CCCCCEEEEEEECCCCEEEEECCCCHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCHHHH
AKKLGEPTWSPILSSFSGQNSSLDIFAVQPIFDSTENLLGVLSNKTTLVKLTNFLKNLYI
HHHHCCCCHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHCEE
SPNGQSFIIERSGNLIASSEVMEPFVIKGTQENRKIERLPATASENKIVSMTTKHLQQKF
CCCCCEEEEECCCCEEECHHHCCCEEEECCCCCCHHHHCCCCCCCCEEEHHHHHHHHHHH
SSFAEITHTHEMNFPIEEEWYYASVIPVIDGRGINWLAVVVIPEDDFMEKVNMNIRTTIL
HHHHHHHHHCCCCCCCCCCEEEEEEEEEECCCCCCEEEEEEECCHHHHHHHCCCHHHHHH
LSFAALTITVLLGIVTTNWITKPILQLNSAAKEISQGKWETQLKIYREDELGELANSFDQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECHHHHHHHHHHHH
MASQLKKSFETLEAQNKQLTELDRLKDEFLANTSHELRTPLNGIIGIGEFLLEENTKNLN
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHCCCCCCH
SITTSNLAIIVSSARRLSNLVNDILDFSKIRYHKLELQVRAIDVRIVVESVITLNRVLVG
HCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEEHHHHHHHHHHHHHHEEC
KNKNLQLTNAIPTDLPPVLADENRLQQILYNLIANAIKFTESGKVEISASLYSPKEDQDE
CCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCC
ATEIIIMVSDTGIGIPPDQLDRIFESFEQGEGSIIRKYGGTGLGLAVTKELVELQGGRIW
CEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHCCCEEE
VESEVGVGSRFNVTLPISNQLVPNSSLNFPSPTVNNIHYLIKNIETTIRSKPLGSKIPNG
EEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
DFHVLVVDDEPINIQVLNNYLKANNYQVTQALSGKEALAALENNHNFDLILLDVMMPNMS
CEEEEEECCCCCEEHEEHHHHHCCCEEEEHHCCCHHHHHHHHCCCCEEEEEEEECCCCCC
GYEVCSQIREKYPAQSLPVLMLTAKNQIADLVMGFQFGANDYLTKPFAKDELLTRIQTHI
HHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
KLSKITKAYERFVPHEYVELLSKESIINVKLGDRVSTKMAIFFSDIRSFTTISEQMTSQE
HHHHHHHHHHHHCCHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TFAFVNGYLKEVCPEIRDRNGLIIKFLGDGIMAVFPDGADDALEAAIAQLKRLQEYNQVL
HHHHHHHHHHHHCHHHHCCCCEEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
LSTGWMPIKIGIGIHWGHIMVGIVGEKGRMSGDAFSNNVNLTSRLEGLTKFYGVSLLISE
HHCCCEEEEEEEEEEECEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEEH
SAFNYLKNPQKYQIRFLDRASVKGIDEPINVYEVLDGEVDEIRELKLQTQVDFALGLESY
HHHHHHCCCCEEEEEEEECCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC
RVGELVDAKDYFEKVLAVNYSDKTAQLYLERIDDLMVTGVPKNWNGVWAFTQK
CCCCCCCHHHHHHHHHEECCCCHHHHHHHHHHHHHEEECCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301; 12176318 [H]