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The map label for this gene is speE [H]

Identifier: 113474146

GI number: 113474146

Start: 389480

End: 390406

Strand: Reverse

Name: speE [H]

Synonym: Tery_0248

Alternate gene names: 113474146

Gene position: 390406-389480 (Counterclockwise)

Preceding gene: 113474147

Following gene: 113474145

Centisome position: 5.04

GC content: 28.8

Gene sequence:

>927_bases
ATGAATAATTACAGATATTGGCAAGTTAAAAATTTAGAAGGAATTCGGGAAAGAATTTATTGGCTCCACAAACAACCTGA
TGGGATAATTTTTTCTCAACCTTCTGGTATACATTTTTTAACTATAAAAAAAGTTAAATTCATTATTCAGTTAGTCTTAG
TAGAGCAAATAACTTTAAAAATGGATTGGGTTCAATCTATACTTAATTTGAATGACCCTATATATTTAATTTTTCCTTAC
ACTCAGGCCATGATGTTAGCTTTACTTTGGAATAGTCAACCAAAAAAAATTTATATTGCAGGTTTTGGTGGGGGTAGTAT
TCCTCAATTTTTACATCACTATTTTCCAGAGGTAATAATAGAATGTACGGAAGTAGATGCTAATATATTGTCAATTGCTC
AGAATTTTTTCGGAGTAGAATTAAATGAGAGATTAAGGGTAAAAATTCAGGATGGTAGGGAATATTTAGAACAAAAAAAT
TGCCAAGATAAGTATGATATTATAATGATTGATGTAGCTTTTGGTAATGGCTATATGTCTTATAATTTAGCGACTCAAGA
ATTTTATCAGCTTTGCGATCGCAATTTATCAAAATCTGGAGTTATAGTTGTCAATATATTAAAAAATAATGGTTTTGAGG
TAGAATATCTGAAAACTATTAAAACTGTCTTTCCACATCTTTATATCTGTAATACTAGTGGCGGAAATACTATTATTATT
GGTACTCGGAACCGTCCAATTGACAAAAAAGAAATTAGAGAAAAAGCTAAATCACTTCAACATTCTCATCAGTTTTCATT
TCCCTTAGTAGATAGGTCAAATAATCTAAAAGTAATAGAAGAATCATCAAATTTTAATTTAGAAAATGTTCCAATTCTCC
AGGATAATGCTTCACCTAGTAATTACTTTAATTCATGGTTATTTTAA

Upstream 100 bases:

>100_bases
GAAGACAGATGTGAGTATTTTAGGGTAACTAATATAAACCTAGTTTCTCTCCTTGAATGATAACAAAATTACCAGATTAA
ATCTGGCTTCTTTTTTCAAA

Downstream 100 bases:

>100_bases
TCAGATAGTAATCAGCAATAAATTAAAAAATTGGAATCAAATAACTATCTAATACCTAATCTATATTAAAAATCTTACAA
TATTTTGACTAATAAATAAT

Product: spermine synthase

Products: NA

Alternate protein names: Putrescine aminopropyltransferase; PAPT; SPDSY [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MNNYRYWQVKNLEGIRERIYWLHKQPDGIIFSQPSGIHFLTIKKVKFIIQLVLVEQITLKMDWVQSILNLNDPIYLIFPY
TQAMMLALLWNSQPKKIYIAGFGGGSIPQFLHHYFPEVIIECTEVDANILSIAQNFFGVELNERLRVKIQDGREYLEQKN
CQDKYDIIMIDVAFGNGYMSYNLATQEFYQLCDRNLSKSGVIVVNILKNNGFEVEYLKTIKTVFPHLYICNTSGGNTIII
GTRNRPIDKKEIREKAKSLQHSHQFSFPLVDRSNNLKVIEESSNFNLENVPILQDNASPSNYFNSWLF

Sequences:

>Translated_308_residues
MNNYRYWQVKNLEGIRERIYWLHKQPDGIIFSQPSGIHFLTIKKVKFIIQLVLVEQITLKMDWVQSILNLNDPIYLIFPY
TQAMMLALLWNSQPKKIYIAGFGGGSIPQFLHHYFPEVIIECTEVDANILSIAQNFFGVELNERLRVKIQDGREYLEQKN
CQDKYDIIMIDVAFGNGYMSYNLATQEFYQLCDRNLSKSGVIVVNILKNNGFEVEYLKTIKTVFPHLYICNTSGGNTIII
GTRNRPIDKKEIREKAKSLQHSHQFSFPLVDRSNNLKVIEESSNFNLENVPILQDNASPSNYFNSWLF
>Mature_308_residues
MNNYRYWQVKNLEGIRERIYWLHKQPDGIIFSQPSGIHFLTIKKVKFIIQLVLVEQITLKMDWVQSILNLNDPIYLIFPY
TQAMMLALLWNSQPKKIYIAGFGGGSIPQFLHHYFPEVIIECTEVDANILSIAQNFFGVELNERLRVKIQDGREYLEQKN
CQDKYDIIMIDVAFGNGYMSYNLATQEFYQLCDRNLSKSGVIVVNILKNNGFEVEYLKTIKTVFPHLYICNTSGGNTIII
GTRNRPIDKKEIREKAKSLQHSHQFSFPLVDRSNNLKVIEESSNFNLENVPILQDNASPSNYFNSWLF

Specific function: Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor [H]

COG id: COG0421

COG function: function code E; Spermidine synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the spermidine/spermine synthase family [H]

Homologues:

Organism=Homo sapiens, GI42542405, Length=214, Percent_Identity=30.3738317757009, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI42542403, Length=214, Percent_Identity=30.3738317757009, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI55956895, Length=214, Percent_Identity=30.3738317757009, Blast_Score=92, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001045 [H]

Pfam domain/function: PF01564 Spermine_synth [H]

EC number: =2.5.1.16 [H]

Molecular weight: Translated: 35877; Mature: 35877

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNYRYWQVKNLEGIRERIYWLHKQPDGIIFSQPSGIHFLTIKKVKFIIQLVLVEQITLK
CCCCEEEEECCHHHHHHHHEEEECCCCCEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHH
MDWVQSILNLNDPIYLIFPYTQAMMLALLWNSQPKKIYIAGFGGGSIPQFLHHYFPEVII
HHHHHHHHCCCCCEEEEECHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHEE
ECTEVDANILSIAQNFFGVELNERLRVKIQDGREYLEQKNCQDKYDIIMIDVAFGNGYMS
EHHCCCHHHHHHHHHHCCCEECCEEEEEECCCHHHHHHCCCCCCCCEEEEEEEECCCEEE
YNLATQEFYQLCDRNLSKSGVIVVNILKNNGFEVEYLKTIKTVFPHLYICNTSGGNTIII
EECCHHHHHHHHCCCCCCCCEEEEEEECCCCCEEHHHHHHHHHCCEEEEEECCCCCEEEE
GTRNRPIDKKEIREKAKSLQHSHQFSFPLVDRSNNLKVIEESSNFNLENVPILQDNASPS
ECCCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCEEEEECCCCCCCCCCCEEECCCCCH
NYFNSWLF
HHHHHCCC
>Mature Secondary Structure
MNNYRYWQVKNLEGIRERIYWLHKQPDGIIFSQPSGIHFLTIKKVKFIIQLVLVEQITLK
CCCCEEEEECCHHHHHHHHEEEECCCCCEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHH
MDWVQSILNLNDPIYLIFPYTQAMMLALLWNSQPKKIYIAGFGGGSIPQFLHHYFPEVII
HHHHHHHHCCCCCEEEEECHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHEE
ECTEVDANILSIAQNFFGVELNERLRVKIQDGREYLEQKNCQDKYDIIMIDVAFGNGYMS
EHHCCCHHHHHHHHHHCCCEECCEEEEEECCCHHHHHHCCCCCCCCEEEEEEEECCCEEE
YNLATQEFYQLCDRNLSKSGVIVVNILKNNGFEVEYLKTIKTVFPHLYICNTSGGNTIII
EECCHHHHHHHHCCCCCCCCEEEEEEECCCCCEEHHHHHHHHHCCEEEEEECCCCCEEEE
GTRNRPIDKKEIREKAKSLQHSHQFSFPLVDRSNNLKVIEESSNFNLENVPILQDNASPS
ECCCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCEEEEECCCCCCCCCCCEEECCCCCH
NYFNSWLF
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]