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The map label for this gene is lktD [H]

Identifier: 113474124

GI number: 113474124

Start: 345347

End: 347230

Strand: Reverse

Name: lktD [H]

Synonym: Tery_0224

Alternate gene names: 113474124

Gene position: 347230-345347 (Counterclockwise)

Preceding gene: 113474125

Following gene: 113474123

Centisome position: 4.48

GC content: 36.57

Gene sequence:

>1884_bases
ATGCCACAAGAATTGAACTTAACTTTAGAGTCAAATGGTCATAAACCTTTAGAGGTTGACTTAGTAACATTAGAAAAAAG
TTTGAAGAATTCTAACTATCAAGAAACAGCAGTTACAAAGTTAGATGAATCTGTTGATGATTGGTCTTTTGCTACTAAAG
AATTATTAGATGCTTTACCACAACGTTGGACACGAGGATTACTATATCTTTTAATAGGATTTGTAGCGATCGCTCTCCCT
TGGGGAATGTTTTCTCAAGTAGATGAAACTGGTTCAGCTAGAGGACGTTTAGAACCTCAAGGTGGTACTTTTAAACAAGA
GCTAAATTTAACGTTTACCGCATATACACAAACGGCAAAAGTTGAGAAAGTTTATGTTAAACAAGGGGATAAAATTAAGG
CTGGAGATATTTTAATAGAATTAGAATCTCGCCCTATTCATGACCGACTTGCTCAACTCCAAATTCAACTGCAAAATCAG
AAAAATCGACTTAGTAAGATTCAACAACAAAAAAATCAATTGGAAATTGAACTTCGTACCCAAGAACGACAAAATGAATC
TCAAAAATTAGAAAAATTAGCTCAAGTGGGGCAAGCACGACAAAACGCACAATCTCTTAAAACAATGTACAATTTACAGG
AACAAGAAAAACTGACCCAAGTTCATCAAGCAGAACAAAATTTGGCGGCTCTCAGAAGAACATTAAATTTACAAAGGGAA
GAAAAATTAGTACAAGTTTATCAAGCAGAAGAAAATTTGGGAGCTCTTAAGAGAGCGTTGAGTTTACAGAAAGAAGAAAA
AATGGCTCAATTCAATCAAGCAAAACGACAATTAAAAGATAGTCAAATTGCTTATCAATTATCAGAAATTCGCTGGGAAA
AGGCTATGAAAGAAGTAGAACGTTATCGTGGTCTTTGGGACCAGGGTGTGGTGACGGAAATACAATTAGTTGAGCATGAA
AATATTGGGCGAGAAAGACAAAGAATGTTGGAGCAAAGTCAAGCAGATATTGAGCAAGCTAAATTACGAATAGAAGAGCA
AGAGGGTAGTTATAAGAGGGTTATTCATCAAGGAAAGGCAGATATTAAGCAAGCTGAATTACGTTTGGCAGAGCAAAAAG
GTAGTTATGAAAGAATTATTAATCAAGGGGAGGCAGATATTGAGCAAGCTGAGTTACGTTTGGCAGAACAAAAGAGTAGT
TATGAAATGGTAATTAATCAAGTTAAGGCAGATATTAAGCAGGCTGAATTACGTTTGAATGAGCAAGAAAATAGCTCTAA
AACTATTACTCATTCTGGGAAAATTGCTATATCAAAAATACAAGAGCAACTTCAGAGTATGGATAGTCAAATTGTTAGTA
TTCAAGGAGAAATTGCTCAGACAAATAAAGAGATTGATTCTTTAAATTTTCAGTTAGAGCAACGAGTAGTTAGGGCGCAA
CAGGGAGGTACTATTTTTAATTTCCCCATCAAAGGTGTGGGAGATGTTGTGCAACAAGGAGAGATGATAGTGGAGATAGC
TCCTAGGGAAACGAGTCTTTTATTAAAGGCGGATATGGCAACTACAGAAAGTGGTTCGTTAAGGGAAGGAATGGAGGTAA
AAATGAAGTTTGATGCCTATCCTTTTCAGGATTATGGTGTAGTTGGGGGATGGTTGAAAGAGATTTCTCCTACTTCAAAA
ATGCAGGAAACTGCTGAGGGAAATGTGGCTATTTATGAGTTAAAGGTTGAGTTGGATGAGTATTGTATTCCTACTGCTAA
TGAGTGTGTTGTTTTGCGTCCGGGGGATACGGCAACGGCTGAGGTTGTTGTGCGTCAGCGTCCTTTGATTGATTTTATTC
TTGACCCGTTTAAGAAGTTACAAAAAGGAGGTTTAGAGTTGTAG

Upstream 100 bases:

>100_bases
CCCGGACCTGGAGGAGAAGTAGGTGGGGATATTGCATACAACTTCAGTACAAAAGTAGAGGGTAAATTTTACTAGAAAAA
ATACAATTATTATAAAAGTT

Downstream 100 bases:

>100_bases
AAATAATTAATGATTGACGGTTAATTAGGGTTACCAGAAGTTGATAATATTATGTTGGTTTGAATAGTTATAATTTAAGC
TGGTAGTAAGGCAATAGCCC

Product: secretion protein HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 627; Mature: 626

Protein sequence:

>627_residues
MPQELNLTLESNGHKPLEVDLVTLEKSLKNSNYQETAVTKLDESVDDWSFATKELLDALPQRWTRGLLYLLIGFVAIALP
WGMFSQVDETGSARGRLEPQGGTFKQELNLTFTAYTQTAKVEKVYVKQGDKIKAGDILIELESRPIHDRLAQLQIQLQNQ
KNRLSKIQQQKNQLEIELRTQERQNESQKLEKLAQVGQARQNAQSLKTMYNLQEQEKLTQVHQAEQNLAALRRTLNLQRE
EKLVQVYQAEENLGALKRALSLQKEEKMAQFNQAKRQLKDSQIAYQLSEIRWEKAMKEVERYRGLWDQGVVTEIQLVEHE
NIGRERQRMLEQSQADIEQAKLRIEEQEGSYKRVIHQGKADIKQAELRLAEQKGSYERIINQGEADIEQAELRLAEQKSS
YEMVINQVKADIKQAELRLNEQENSSKTITHSGKIAISKIQEQLQSMDSQIVSIQGEIAQTNKEIDSLNFQLEQRVVRAQ
QGGTIFNFPIKGVGDVVQQGEMIVEIAPRETSLLLKADMATTESGSLREGMEVKMKFDAYPFQDYGVVGGWLKEISPTSK
MQETAEGNVAIYELKVELDEYCIPTANECVVLRPGDTATAEVVVRQRPLIDFILDPFKKLQKGGLEL

Sequences:

>Translated_627_residues
MPQELNLTLESNGHKPLEVDLVTLEKSLKNSNYQETAVTKLDESVDDWSFATKELLDALPQRWTRGLLYLLIGFVAIALP
WGMFSQVDETGSARGRLEPQGGTFKQELNLTFTAYTQTAKVEKVYVKQGDKIKAGDILIELESRPIHDRLAQLQIQLQNQ
KNRLSKIQQQKNQLEIELRTQERQNESQKLEKLAQVGQARQNAQSLKTMYNLQEQEKLTQVHQAEQNLAALRRTLNLQRE
EKLVQVYQAEENLGALKRALSLQKEEKMAQFNQAKRQLKDSQIAYQLSEIRWEKAMKEVERYRGLWDQGVVTEIQLVEHE
NIGRERQRMLEQSQADIEQAKLRIEEQEGSYKRVIHQGKADIKQAELRLAEQKGSYERIINQGEADIEQAELRLAEQKSS
YEMVINQVKADIKQAELRLNEQENSSKTITHSGKIAISKIQEQLQSMDSQIVSIQGEIAQTNKEIDSLNFQLEQRVVRAQ
QGGTIFNFPIKGVGDVVQQGEMIVEIAPRETSLLLKADMATTESGSLREGMEVKMKFDAYPFQDYGVVGGWLKEISPTSK
MQETAEGNVAIYELKVELDEYCIPTANECVVLRPGDTATAEVVVRQRPLIDFILDPFKKLQKGGLEL
>Mature_626_residues
PQELNLTLESNGHKPLEVDLVTLEKSLKNSNYQETAVTKLDESVDDWSFATKELLDALPQRWTRGLLYLLIGFVAIALPW
GMFSQVDETGSARGRLEPQGGTFKQELNLTFTAYTQTAKVEKVYVKQGDKIKAGDILIELESRPIHDRLAQLQIQLQNQK
NRLSKIQQQKNQLEIELRTQERQNESQKLEKLAQVGQARQNAQSLKTMYNLQEQEKLTQVHQAEQNLAALRRTLNLQREE
KLVQVYQAEENLGALKRALSLQKEEKMAQFNQAKRQLKDSQIAYQLSEIRWEKAMKEVERYRGLWDQGVVTEIQLVEHEN
IGRERQRMLEQSQADIEQAKLRIEEQEGSYKRVIHQGKADIKQAELRLAEQKGSYERIINQGEADIEQAELRLAEQKSSY
EMVINQVKADIKQAELRLNEQENSSKTITHSGKIAISKIQEQLQSMDSQIVSIQGEIAQTNKEIDSLNFQLEQRVVRAQQ
GGTIFNFPIKGVGDVVQQGEMIVEIAPRETSLLLKADMATTESGSLREGMEVKMKFDAYPFQDYGVVGGWLKEISPTSKM
QETAEGNVAIYELKVELDEYCIPTANECVVLRPGDTATAEVVVRQRPLIDFILDPFKKLQKGGLEL

Specific function: Involved in the transport of the hemolysin/leukotoxin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 71594; Mature: 71463

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQELNLTLESNGHKPLEVDLVTLEKSLKNSNYQETAVTKLDESVDDWSFATKELLDALP
CCCCEEEEEECCCCCCEEEEHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHH
QRWTRGLLYLLIGFVAIALPWGMFSQVDETGSARGRLEPQGGTFKQELNLTFTAYTQTAK
HHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCCCHHHCCEEEEEEECHHH
VEKVYVKQGDKIKAGDILIELESRPIHDRLAQLQIQLQNQKNRLSKIQQQKNQLEIELRT
HHHHHCCCCCEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEC
QERQNESQKLEKLAQVGQARQNAQSLKTMYNLQEQEKLTQVHQAEQNLAALRRTLNLQRE
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
EKLVQVYQAEENLGALKRALSLQKEEKMAQFNQAKRQLKDSQIAYQLSEIRWEKAMKEVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYRGLWDQGVVTEIQLVEHENIGRERQRMLEQSQADIEQAKLRIEEQEGSYKRVIHQGKA
HHCCCCCCCCHHHEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCHH
DIKQAELRLAEQKGSYERIINQGEADIEQAELRLAEQKSSYEMVINQVKADIKQAELRLN
HHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EQENSSKTITHSGKIAISKIQEQLQSMDSQIVSIQGEIAQTNKEIDSLNFQLEQRVVRAQ
CCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
QGGTIFNFPIKGVGDVVQQGEMIVEIAPRETSLLLKADMATTESGSLREGMEVKMKFDAY
CCCEEEECCCCCHHHHHHCCCEEEEECCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCC
PFQDYGVVGGWLKEISPTSKMQETAEGNVAIYELKVELDEYCIPTANECVVLRPGDTATA
CCCCCCCHHHHHHHCCCHHHHHHHCCCCEEEEEEEEEHHHCCCCCCCCEEEECCCCCCHH
EVVVRQRPLIDFILDPFKKLQKGGLEL
HHHHHCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PQELNLTLESNGHKPLEVDLVTLEKSLKNSNYQETAVTKLDESVDDWSFATKELLDALP
CCCEEEEEECCCCCCEEEEHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHH
QRWTRGLLYLLIGFVAIALPWGMFSQVDETGSARGRLEPQGGTFKQELNLTFTAYTQTAK
HHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCCCHHHCCEEEEEEECHHH
VEKVYVKQGDKIKAGDILIELESRPIHDRLAQLQIQLQNQKNRLSKIQQQKNQLEIELRT
HHHHHCCCCCEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEC
QERQNESQKLEKLAQVGQARQNAQSLKTMYNLQEQEKLTQVHQAEQNLAALRRTLNLQRE
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
EKLVQVYQAEENLGALKRALSLQKEEKMAQFNQAKRQLKDSQIAYQLSEIRWEKAMKEVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYRGLWDQGVVTEIQLVEHENIGRERQRMLEQSQADIEQAKLRIEEQEGSYKRVIHQGKA
HHCCCCCCCCHHHEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCHH
DIKQAELRLAEQKGSYERIINQGEADIEQAELRLAEQKSSYEMVINQVKADIKQAELRLN
HHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EQENSSKTITHSGKIAISKIQEQLQSMDSQIVSIQGEIAQTNKEIDSLNFQLEQRVVRAQ
CCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
QGGTIFNFPIKGVGDVVQQGEMIVEIAPRETSLLLKADMATTESGSLREGMEVKMKFDAY
CCCEEEECCCCCHHHHHHCCCEEEEECCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCC
PFQDYGVVGGWLKEISPTSKMQETAEGNVAIYELKVELDEYCIPTANECVVLRPGDTATA
CCCCCCCHHHHHHHCCCHHHHHHHCCCCEEEEEEEEEHHHCCCCCCCCEEEECCCCCCHH
EVVVRQRPLIDFILDPFKKLQKGGLEL
HHHHHCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2402458; 1961107 [H]