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The map label for this gene is atpB

Identifier: 110835593

GI number: 110835593

Start: 3088561

End: 3089469

Strand: Reverse

Name: atpB

Synonym: ABO_2732

Alternate gene names: 110835593

Gene position: 3089469-3088561 (Counterclockwise)

Preceding gene: 110835594

Following gene: 110835592

Centisome position: 99.02

GC content: 51.27

Gene sequence:

>909_bases
ATGGCAGCGAACTCCGCCGGCGAGTATATCAAGCACCATCTGGGCAATCTGACCTATGGCAAACTGCCGGAAGGCTATGT
CCGTGAATGTCACGGTCATGCGGAGACTCTGAGCCAGGCAACCTGGACCATGGCGTGTAACGGCACCGAAGCCAAAGATA
TGGGTTTTGCAGCCTTTCACGTTGACTCCTTAGCTTGGTCTGGCGGTCTTGGCATTATCATGTGCCTGTTGTTCTGGTTG
GGCGCGCGTAAAGCGACTGCCGGTGTGCCTTCTGGTTTCCTTAATTTTGTGGAAATCATCATTGAGTTTATCGATACACA
GGTGCGTGACTCTTTCCACGGCAAGAGCAAGTTGATTGCGCCGCTGTCGTTGGTGATCTTCTGTTGGGTGTTCTTGATGA
ACCTGATGGATCTGATCCCGGTGGATTTCATTCCGAAGACATTTGAATGGGTGATGGTGACCTTCTTCGGTTGGAGTGCA
CACGAAGCCTATTTCAAGATTGTTCCCAGCACCGACCCGAACATTACCTTGGGTATGTCCTTCAGCGTGATGTTCCTGAT
TATCTTCCTCACCATTAAGACTAAGGGTGTGGGCGGTTTTGTGGGTACTCTAGCGTTGCATCCTTTTGAATCCGGCAACC
CGGTGGTCAAGGCGCTTCTGATCCCGATTAACCTGTTGCTGGAAACCATTGCTCTACTGGCCAAGCCGGTATCTCTGGGC
CTGCGACTGTTCGGTAATATGTACGCGGGTGAGTTTGTATTTATTCTGCTGGCAGCGATGATGGGCACCTGGCAATTCAT
CGGTGCCTGGCCTTGGGCGGTGTTCCATATTTTGGTAATCACCCTGCAGGCATTTATCTTCATGGTTCTGACCATCGTGT
ATTTGAGCATGGCGGTCGAAGAGCACTGA

Upstream 100 bases:

>100_bases
TGTGGGTTGGATTCAGGTAGCACGCCTCGACGGGCAAACAGCAGGGCAAGACAGGCACAATGACTAGCCTGTAGGCATCG
GCTCTCTATAGAGGTTTGAC

Downstream 100 bases:

>100_bases
TTTAAGTAAGTAACAGTTTTTTTAAACCGGTTTTTAATTAAACCAACCAAGCACTTAACGGGAGTGTAAAGATGGAAGGC
ATTCAATTTCTTGCTGCTGC

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MAANSAGEYIKHHLGNLTYGKLPEGYVRECHGHAETLSQATWTMACNGTEAKDMGFAAFHVDSLAWSGGLGIIMCLLFWL
GARKATAGVPSGFLNFVEIIIEFIDTQVRDSFHGKSKLIAPLSLVIFCWVFLMNLMDLIPVDFIPKTFEWVMVTFFGWSA
HEAYFKIVPSTDPNITLGMSFSVMFLIIFLTIKTKGVGGFVGTLALHPFESGNPVVKALLIPINLLLETIALLAKPVSLG
LRLFGNMYAGEFVFILLAAMMGTWQFIGAWPWAVFHILVITLQAFIFMVLTIVYLSMAVEEH

Sequences:

>Translated_302_residues
MAANSAGEYIKHHLGNLTYGKLPEGYVRECHGHAETLSQATWTMACNGTEAKDMGFAAFHVDSLAWSGGLGIIMCLLFWL
GARKATAGVPSGFLNFVEIIIEFIDTQVRDSFHGKSKLIAPLSLVIFCWVFLMNLMDLIPVDFIPKTFEWVMVTFFGWSA
HEAYFKIVPSTDPNITLGMSFSVMFLIIFLTIKTKGVGGFVGTLALHPFESGNPVVKALLIPINLLLETIALLAKPVSLG
LRLFGNMYAGEFVFILLAAMMGTWQFIGAWPWAVFHILVITLQAFIFMVLTIVYLSMAVEEH
>Mature_301_residues
AANSAGEYIKHHLGNLTYGKLPEGYVRECHGHAETLSQATWTMACNGTEAKDMGFAAFHVDSLAWSGGLGIIMCLLFWLG
ARKATAGVPSGFLNFVEIIIEFIDTQVRDSFHGKSKLIAPLSLVIFCWVFLMNLMDLIPVDFIPKTFEWVMVTFFGWSAH
EAYFKIVPSTDPNITLGMSFSVMFLIIFLTIKTKGVGGFVGTLALHPFESGNPVVKALLIPINLLLETIALLAKPVSLGL
RLFGNMYAGEFVFILLAAMMGTWQFIGAWPWAVFHILVITLQAFIFMVLTIVYLSMAVEEH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family

Homologues:

Organism=Escherichia coli, GI1790176, Length=281, Percent_Identity=49.8220640569395, Blast_Score=241, Evalue=6e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATP6_ALCBS (Q0VKW8)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_694452.1
- ProteinModelPortal:   Q0VKW8
- SMR:   Q0VKW8
- STRING:   Q0VKW8
- GeneID:   4213843
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_2732
- NMPDR:   fig|393595.12.peg.2741
- eggNOG:   COG0356
- HOGENOM:   HBG734175
- OMA:   MAEQTAS
- PhylomeDB:   Q0VKW8
- ProtClustDB:   PRK05815
- BioCyc:   ABOR393595:ABO_2732-MONOMER
- HAMAP:   MF_01393
- InterPro:   IPR000568
- InterPro:   IPR023011
- Gene3D:   G3DSA:1.20.120.220
- PANTHER:   PTHR11410
- TIGRFAMs:   TIGR01131

Pfam domain/function: PF00119 ATP-synt_A; SSF81336 ATPase_F0_A

EC number: 3.6.3.14

Molecular weight: Translated: 33426; Mature: 33295

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x15105afc)-; HASH(0x147b7480)-; HASH(0x14a6d018)-; HASH(0x153f4648)-; HASH(0x151f12c0)-; HASH(0x151ce1cc)-; HASH(0x150bbc68)-;

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAANSAGEYIKHHLGNLTYGKLPEGYVRECHGHAETLSQATWTMACNGTEAKDMGFAAFH
CCCCCHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHHHHHHHEEEEECCCCCHHCCCHHEE
VDSLAWSGGLGIIMCLLFWLGARKATAGVPSGFLNFVEIIIEFIDTQVRDSFHGKSKLIA
HHHHHCCCCHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
PLSLVIFCWVFLMNLMDLIPVDFIPKTFEWVMVTFFGWSAHEAYFKIVPSTDPNITLGMS
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEECHH
FSVMFLIIFLTIKTKGVGGFVGTLALHPFESGNPVVKALLIPINLLLETIALLAKPVSLG
HHHHHHHHHHHHHCCCCCHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRLFGNMYAGEFVFILLAAMMGTWQFIGAWPWAVFHILVITLQAFIFMVLTIVYLSMAVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EH
CH
>Mature Secondary Structure 
AANSAGEYIKHHLGNLTYGKLPEGYVRECHGHAETLSQATWTMACNGTEAKDMGFAAFH
CCCCHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHHHHHHHEEEEECCCCCHHCCCHHEE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CH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA