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The map label for this gene is 110835367

Identifier: 110835367

GI number: 110835367

Start: 2842197

End: 2843996

Strand: Direct

Name: 110835367

Synonym: ABO_2506

Alternate gene names: NA

Gene position: 2842197-2843996 (Clockwise)

Preceding gene: 110835365

Following gene: 110835368

Centisome position: 91.09

GC content: 61.11

Gene sequence:

>1800_bases
ATGATTGGCTGGACTCTTCAACAATGGCAGATGGCCTACCGCAGCGGTGAACTCACCCCGGTACAGGCCATGAAACAACT
GGCCACCACTCTGCAGGATAGTGAGCGCGCCCTGTGGATCCATCTCCTGGATGAGGCTTCCTTGACGGCCCAGGCGCAAG
CGCTAACGGATCCATCGCTGCCACTCTATGGCATTCCCTTTGCCGTGAAAGACAACATTGATGTTGTGGGCATGCCCACA
ACAGCAGCCTGCCCGGCATTCGCCTACACCCCGACGGAAGACGCCACCGTGGTACGACTACTGCGCGACGCCGGCGCCAT
CGTCGTAGGCAAGACCAATCTGGATCAGTTTGCCACCGGTCTGGTTGGCACTCGTTCCCCCTATGGCGAAGTACCCAATC
CATTCAACCCGGATTACCTCAGTGGTGGCTCCAGTTCAGGTTCCGCCACGGCCGTGAGCCTGGGCCTGGTACCCTTTTCA
CTGGGCACCGATACCGCCGGTTCCGGCCGGGTACCTGCAGCGTTCACCAACACGGTGGGCCTCAAGCCCACCCGCGGTGC
CATTAGCACCCACGGTGTTGTTCCTGCCTGCCGGACCCTTGATTGCGTCAGCATCTTTGCCCTGAACGTGGACGATGCCC
AAGAGATCTTTCGACTCATCAGCCAGTTCGACAGCGCAGATCCTTACAGCCGCGCAGCTCCCCGATTGCTAACCACCGGA
CTCCCCGAACGCCCGACTCTCGGCATCCCCAAAGACCTTCCCTGGTTCGAGGATAGCCAAGCCCAACAGCTGTGGGAGCG
ACAGCTGGACCAGCTCAGAGAGATTGCCAACCTGATCACTATCGACACCACGGTGTTGCAGGATGCCGCCGCTTTACTCT
ATCAGGGCCCCTGGGTGGCGGAACGTTTCATTGTCACCGAACCCTTGTTGCAAAAAAGCCCCTACACCTTGCTGCCAGTA
ATTCGTGACATTCTCGCCCCCGCCGCCGCCCTGACAGCAGCGGACAGTTTCCGGGCCCAGTACCAGCTGGCTGAATTGAA
ACGGCAGTCCGAAGCACTAATGGCCCAGGTTGATGCATTGTTGCTCCCCACTACGCCCGGCATCTACACCCGCGCCGCCG
TGCAAGCCAACCCCATCACCCTGAACAGCCAGCTAGGCACCTGGACCAATTTCGTCAACCTCTTGGACCTGTGCGCCCTG
GCATTGCCCGGCGGCTTCCGTGAAGACGGCTTGCCCGGCGGTGTCACCCTAATTGGCCCCGCTTGGCAGGACCACGCCCT
GGCCGACTTCGGCCGGCGCTGGCAGCAGGCCCAGCCCTGGCAGGCCGGCGCTACCGGACAGCGGCTGGCCAAGCCGCAGA
CCCATGCGGCCAATGATGATGAGGACGATGTAATGACTGTCGCCGTGGTTGGCGCACACCTTTCCGGCATGCCCCTCAAT
ACCCAGCTCACCGAACGCGACGGCGTGTTGCTCGAAGCCACCCACACGGCGCCCTGTTATCGGCTCTACGCCCTGGCCAA
CACTGTGCCGCCCAAACCCGGGCTGATTCGTAGCGAAAAAGACGGGGGTGACTGCATTCCCATCGAGCTGTGGCGAATGC
CGATGAAGCACTTCGGCAGTTTTGTCGGCTTAATCCCCGCCCCACTGGGCATCGGTAGTCTGGAAACCACCGACGGTCGC
TGGGTGAAAGGCTTTATCTGTGAACCCTGGGCCATTGGGGACGCCACCGACATTACCGCACTGGGCGGCTGGAGAAACTA
CATCGCGCAAGTGGCGACAAACGCTCAGGAAACACACTGA

Upstream 100 bases:

>100_bases
TTAATTACTGTAAAAACAAAGCGTTAAATATTTTTCATGGCTGGCACCCCCTTTGCACAAATAAGAATACCAACTTGTGT
ACAACCAGGTGTGCTAACGA

Downstream 100 bases:

>100_bases
TGAAGCCGTGGCGCTGGGGGGCGCTAACCGCTGCAAAACAGCGTTGTGAATTCGGTCTCACGGCACAGAACGCCGCTAGC
AGCGACCGCCACAGCCATCT

Product: allophanate hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 599; Mature: 599

Protein sequence:

>599_residues
MIGWTLQQWQMAYRSGELTPVQAMKQLATTLQDSERALWIHLLDEASLTAQAQALTDPSLPLYGIPFAVKDNIDVVGMPT
TAACPAFAYTPTEDATVVRLLRDAGAIVVGKTNLDQFATGLVGTRSPYGEVPNPFNPDYLSGGSSSGSATAVSLGLVPFS
LGTDTAGSGRVPAAFTNTVGLKPTRGAISTHGVVPACRTLDCVSIFALNVDDAQEIFRLISQFDSADPYSRAAPRLLTTG
LPERPTLGIPKDLPWFEDSQAQQLWERQLDQLREIANLITIDTTVLQDAAALLYQGPWVAERFIVTEPLLQKSPYTLLPV
IRDILAPAAALTAADSFRAQYQLAELKRQSEALMAQVDALLLPTTPGIYTRAAVQANPITLNSQLGTWTNFVNLLDLCAL
ALPGGFREDGLPGGVTLIGPAWQDHALADFGRRWQQAQPWQAGATGQRLAKPQTHAANDDEDDVMTVAVVGAHLSGMPLN
TQLTERDGVLLEATHTAPCYRLYALANTVPPKPGLIRSEKDGGDCIPIELWRMPMKHFGSFVGLIPAPLGIGSLETTDGR
WVKGFICEPWAIGDATDITALGGWRNYIAQVATNAQETH

Sequences:

>Translated_599_residues
MIGWTLQQWQMAYRSGELTPVQAMKQLATTLQDSERALWIHLLDEASLTAQAQALTDPSLPLYGIPFAVKDNIDVVGMPT
TAACPAFAYTPTEDATVVRLLRDAGAIVVGKTNLDQFATGLVGTRSPYGEVPNPFNPDYLSGGSSSGSATAVSLGLVPFS
LGTDTAGSGRVPAAFTNTVGLKPTRGAISTHGVVPACRTLDCVSIFALNVDDAQEIFRLISQFDSADPYSRAAPRLLTTG
LPERPTLGIPKDLPWFEDSQAQQLWERQLDQLREIANLITIDTTVLQDAAALLYQGPWVAERFIVTEPLLQKSPYTLLPV
IRDILAPAAALTAADSFRAQYQLAELKRQSEALMAQVDALLLPTTPGIYTRAAVQANPITLNSQLGTWTNFVNLLDLCAL
ALPGGFREDGLPGGVTLIGPAWQDHALADFGRRWQQAQPWQAGATGQRLAKPQTHAANDDEDDVMTVAVVGAHLSGMPLN
TQLTERDGVLLEATHTAPCYRLYALANTVPPKPGLIRSEKDGGDCIPIELWRMPMKHFGSFVGLIPAPLGIGSLETTDGR
WVKGFICEPWAIGDATDITALGGWRNYIAQVATNAQETH
>Mature_599_residues
MIGWTLQQWQMAYRSGELTPVQAMKQLATTLQDSERALWIHLLDEASLTAQAQALTDPSLPLYGIPFAVKDNIDVVGMPT
TAACPAFAYTPTEDATVVRLLRDAGAIVVGKTNLDQFATGLVGTRSPYGEVPNPFNPDYLSGGSSSGSATAVSLGLVPFS
LGTDTAGSGRVPAAFTNTVGLKPTRGAISTHGVVPACRTLDCVSIFALNVDDAQEIFRLISQFDSADPYSRAAPRLLTTG
LPERPTLGIPKDLPWFEDSQAQQLWERQLDQLREIANLITIDTTVLQDAAALLYQGPWVAERFIVTEPLLQKSPYTLLPV
IRDILAPAAALTAADSFRAQYQLAELKRQSEALMAQVDALLLPTTPGIYTRAAVQANPITLNSQLGTWTNFVNLLDLCAL
ALPGGFREDGLPGGVTLIGPAWQDHALADFGRRWQQAQPWQAGATGQRLAKPQTHAANDDEDDVMTVAVVGAHLSGMPLN
TQLTERDGVLLEATHTAPCYRLYALANTVPPKPGLIRSEKDGGDCIPIELWRMPMKHFGSFVGLIPAPLGIGSLETTDGR
WVKGFICEPWAIGDATDITALGGWRNYIAQVATNAQETH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI222831590, Length=503, Percent_Identity=27.6341948310139, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI195972892, Length=160, Percent_Identity=32.5, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17543272, Length=407, Percent_Identity=29.7297297297297, Blast_Score=122, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17556264, Length=256, Percent_Identity=30.46875, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17537465, Length=436, Percent_Identity=25.2293577981651, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17538252, Length=195, Percent_Identity=28.7179487179487, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71990152, Length=226, Percent_Identity=27.8761061946903, Blast_Score=72, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6319685, Length=610, Percent_Identity=44.9180327868852, Blast_Score=484, Evalue=1e-137,
Organism=Saccharomyces cerevisiae, GI6323950, Length=225, Percent_Identity=37.3333333333333, Blast_Score=109, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6320448, Length=131, Percent_Identity=35.8778625954198, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24648113, Length=276, Percent_Identity=35.5072463768116, Blast_Score=112, Evalue=1e-24,
Organism=Drosophila melanogaster, GI21356731, Length=135, Percent_Identity=34.0740740740741, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24652985, Length=473, Percent_Identity=24.7357293868922, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI19922090, Length=473, Percent_Identity=24.7357293868922, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24652981, Length=473, Percent_Identity=24.7357293868922, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24652983, Length=473, Percent_Identity=24.7357293868922, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24644968, Length=199, Percent_Identity=27.6381909547739, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45550774, Length=138, Percent_Identity=35.5072463768116, Blast_Score=67, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24648435, Length=138, Percent_Identity=35.5072463768116, Blast_Score=66, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24648437, Length=138, Percent_Identity=35.5072463768116, Blast_Score=66, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: =3.5.1.4 [H]

Molecular weight: Translated: 64483; Mature: 64483

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGWTLQQWQMAYRSGELTPVQAMKQLATTLQDSERALWIHLLDEASLTAQAQALTDPSL
CCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHCCCCCC
PLYGIPFAVKDNIDVVGMPTTAACPAFAYTPTEDATVVRLLRDAGAIVVGKTNLDQFATG
CEEECCEEEECCCEEEECCCHHCCCCEEECCCCCHHHHHHHHHCCEEEEECCCHHHHHHH
LVGTRSPYGEVPNPFNPDYLSGGSSSGSATAVSLGLVPFSLGTDTAGSGRVPAAFTNTVG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECEEEECCCCCCCCCCCCEEECCCCC
LKPTRGAISTHGVVPACRTLDCVSIFALNVDDAQEIFRLISQFDSADPYSRAAPRLLTTG
CCCCCCCCCCCCCCCHHHHHHEEEEEEECCCCHHHHHHHHHHHCCCCCHHHHCCHHHHCC
LPERPTLGIPKDLPWFEDSQAQQLWERQLDQLREIANLITIDTTVLQDAAALLYQGPWVA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ERFIVTEPLLQKSPYTLLPVIRDILAPAAALTAADSFRAQYQLAELKRQSEALMAQVDAL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
LLPTTPGIYTRAAVQANPITLNSQLGTWTNFVNLLDLCALALPGGFREDGLPGGVTLIGP
EECCCCCCEEEEEEECCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECC
AWQDHALADFGRRWQQAQPWQAGATGQRLAKPQTHAANDDEDDVMTVAVVGAHLSGMPLN
CCCCHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCCCCEEEEEEEHHHHCCCCCC
TQLTERDGVLLEATHTAPCYRLYALANTVPPKPGLIRSEKDGGDCIPIELWRMPMKHFGS
CEEECCCCEEEEECCCCHHHHHHHHHHCCCCCCCCEECCCCCCCEEEHHHHHHHHHHHHH
FVGLIPAPLGIGSLETTDGRWVKGFICEPWAIGDATDITALGGWRNYIAQVATNAQETH
HHHHHCCCCCCCCCCCCCCCEEEEEEECCEECCCCCCEEECCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MIGWTLQQWQMAYRSGELTPVQAMKQLATTLQDSERALWIHLLDEASLTAQAQALTDPSL
CCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHCCCCCC
PLYGIPFAVKDNIDVVGMPTTAACPAFAYTPTEDATVVRLLRDAGAIVVGKTNLDQFATG
CEEECCEEEECCCEEEECCCHHCCCCEEECCCCCHHHHHHHHHCCEEEEECCCHHHHHHH
LVGTRSPYGEVPNPFNPDYLSGGSSSGSATAVSLGLVPFSLGTDTAGSGRVPAAFTNTVG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECEEEECCCCCCCCCCCCEEECCCCC
LKPTRGAISTHGVVPACRTLDCVSIFALNVDDAQEIFRLISQFDSADPYSRAAPRLLTTG
CCCCCCCCCCCCCCCHHHHHHEEEEEEECCCCHHHHHHHHHHHCCCCCHHHHCCHHHHCC
LPERPTLGIPKDLPWFEDSQAQQLWERQLDQLREIANLITIDTTVLQDAAALLYQGPWVA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ERFIVTEPLLQKSPYTLLPVIRDILAPAAALTAADSFRAQYQLAELKRQSEALMAQVDAL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
LLPTTPGIYTRAAVQANPITLNSQLGTWTNFVNLLDLCALALPGGFREDGLPGGVTLIGP
EECCCCCCEEEEEEECCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECC
AWQDHALADFGRRWQQAQPWQAGATGQRLAKPQTHAANDDEDDVMTVAVVGAHLSGMPLN
CCCCHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCCCCEEEEEEEHHHHCCCCCC
TQLTERDGVLLEATHTAPCYRLYALANTVPPKPGLIRSEKDGGDCIPIELWRMPMKHFGS
CEEECCCCEEEEECCCCHHHHHHHHHHCCCCCCCCEECCCCCCCEEEHHHHHHHHHHHHH
FVGLIPAPLGIGSLETTDGRWVKGFICEPWAIGDATDITALGGWRNYIAQVATNAQETH
HHHHHCCCCCCCCCCCCCCCEEEEEEECCEECCCCCCEEECCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9809753 [H]