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The map label for this gene is yqhD [H]

Identifier: 110835280

GI number: 110835280

Start: 2737574

End: 2738731

Strand: Direct

Name: yqhD [H]

Synonym: ABO_2419

Alternate gene names: 110835280

Gene position: 2737574-2738731 (Clockwise)

Preceding gene: 110835279

Following gene: 110835281

Centisome position: 87.74

GC content: 56.99

Gene sequence:

>1158_bases
ATGAACAACTTTGATTTCTACAACCCCACTCGTATCGCCTTTGGCGAAGGAAAAATTGCGGCTCTCGACACCCTGGTTCC
CGCCAACGCCAACGTGCTGATTCTGTTTGGGGGCGAAAGCGCGCGCCGCACCGGCACCCTGACCGAAGTGGAAGCGGCAT
TGGGCGATCGTCGCGTACAGCTCTTTGGTGGCATTGAACCCAACCCCAGTTTTGAAACCCTGATGGAAGCGGTGAGCGTG
GTACAGCGTGATGGCATCGATTATCTGCTGGCTGTGGGCGGAGGATCCGTAATCGACGGCACCAAGTTTGTCGCGGCGGC
TTCGCTATTCGAGGGGGATGCTTGGAACATCCTGCTCAAGGGCGGCAGCAATATTCACCGCGCCCTACCGTTCGGCTCGG
TACTGACCTTGCCCGCCACGGGATCGGAAATGAACAAGGGCGCCGTGGTAACGCGCAAGTCGCTGCATGCGAAGCTCCCT
TTCCACAGTGAGCATGTGTTCCCGCAATTTTCCGTGTTGGATCCCACTAAAAGCTACACCTTGCCGCCCCGGCAAGTGGC
CAACGGTGTGGTCGATGCCTTTGTTCATATTGTTGAGCAATACCTGACCTATCCAGCCGACGCTCCCGTGCAAGACCGAT
TCGCGGAAGGCTTGCTGCAAACGCTGATTGAAATTGGCCCGCAGGCCTTAGCGGAACCAGAACATTATCAGGTACGCGCT
AACCTAATGTGGGTGGCCACCCTAGCGCTGAATGGCCTGATTGGCTCCGGCGTTCCTCAGGACTGGGCTACACATATGCT
GGGGCATGAGCTCACGGCCCTGCATGGCCTGGATCATGCTCAAACCTTAGCCATTGTCCTCCCGACAATGCTGGCTGAGC
GCAAGGAAGCAAAACGCGACAAACTGGTGCAGTACGCGCAGCGGGTTTGGGCTATCAACGAAGGCAGTGATGAACAGAAG
GCGGATTTGGCCATTGAAAAAACCCGTGATTTCTTCGAAGGCCTAGGCGTGAAAACCCGGCTAGCGGACTATCAATTGGC
TGCCGAGCACATTGAGCCGCTTATCGACAGCCTTGAAGCGCATGGCATGACGGCTCTGGGGGAACACAACGACGTCACCC
CTGAGGTATGCCGCCGAGTACTGCACGCCAGCCTTTAA

Upstream 100 bases:

>100_bases
CACAGAACGCCACAGGCCCGCGGTTTAGCGGGCTTTTTTACCGGCCATCTATAGACGACCGGTCTAATTTAAACGCATCA
CCGACCAAGGATACCGCATC

Downstream 100 bases:

>100_bases
CAAGGGCGCGAGCACTCCCTTTACAACACCATCATCCCGACCCGGGGTGATGGTGAAATCACAGAACGGAGATCACCCAA
TGAATATTCTGATGATTCTT

Product: NADH-dependent alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MNNFDFYNPTRIAFGEGKIAALDTLVPANANVLILFGGESARRTGTLTEVEAALGDRRVQLFGGIEPNPSFETLMEAVSV
VQRDGIDYLLAVGGGSVIDGTKFVAAASLFEGDAWNILLKGGSNIHRALPFGSVLTLPATGSEMNKGAVVTRKSLHAKLP
FHSEHVFPQFSVLDPTKSYTLPPRQVANGVVDAFVHIVEQYLTYPADAPVQDRFAEGLLQTLIEIGPQALAEPEHYQVRA
NLMWVATLALNGLIGSGVPQDWATHMLGHELTALHGLDHAQTLAIVLPTMLAERKEAKRDKLVQYAQRVWAINEGSDEQK
ADLAIEKTRDFFEGLGVKTRLADYQLAAEHIEPLIDSLEAHGMTALGEHNDVTPEVCRRVLHASL

Sequences:

>Translated_385_residues
MNNFDFYNPTRIAFGEGKIAALDTLVPANANVLILFGGESARRTGTLTEVEAALGDRRVQLFGGIEPNPSFETLMEAVSV
VQRDGIDYLLAVGGGSVIDGTKFVAAASLFEGDAWNILLKGGSNIHRALPFGSVLTLPATGSEMNKGAVVTRKSLHAKLP
FHSEHVFPQFSVLDPTKSYTLPPRQVANGVVDAFVHIVEQYLTYPADAPVQDRFAEGLLQTLIEIGPQALAEPEHYQVRA
NLMWVATLALNGLIGSGVPQDWATHMLGHELTALHGLDHAQTLAIVLPTMLAERKEAKRDKLVQYAQRVWAINEGSDEQK
ADLAIEKTRDFFEGLGVKTRLADYQLAAEHIEPLIDSLEAHGMTALGEHNDVTPEVCRRVLHASL
>Mature_385_residues
MNNFDFYNPTRIAFGEGKIAALDTLVPANANVLILFGGESARRTGTLTEVEAALGDRRVQLFGGIEPNPSFETLMEAVSV
VQRDGIDYLLAVGGGSVIDGTKFVAAASLFEGDAWNILLKGGSNIHRALPFGSVLTLPATGSEMNKGAVVTRKSLHAKLP
FHSEHVFPQFSVLDPTKSYTLPPRQVANGVVDAFVHIVEQYLTYPADAPVQDRFAEGLLQTLIEIGPQALAEPEHYQVRA
NLMWVATLALNGLIGSGVPQDWATHMLGHELTALHGLDHAQTLAIVLPTMLAERKEAKRDKLVQYAQRVWAINEGSDEQK
ADLAIEKTRDFFEGLGVKTRLADYQLAAEHIEPLIDSLEAHGMTALGEHNDVTPEVCRRVLHASL

Specific function: NADP-dependent ADH activity [H]

COG id: COG1979

COG function: function code C; Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789386, Length=386, Percent_Identity=62.1761658031088, Blast_Score=487, Evalue=1e-139,
Organism=Escherichia coli, GI48994951, Length=314, Percent_Identity=22.9299363057325, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789163, Length=301, Percent_Identity=26.578073089701, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082107, Length=284, Percent_Identity=22.887323943662, Blast_Score=69, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6321181, Length=356, Percent_Identity=24.7191011235955, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24657991, Length=328, Percent_Identity=25.609756097561, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 41869; Mature: 41869

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNFDFYNPTRIAFGEGKIAALDTLVPANANVLILFGGESARRTGTLTEVEAALGDRRVQ
CCCCCCCCCCEEEECCCCEEEEEEECCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCEEE
LFGGIEPNPSFETLMEAVSVVQRDGIDYLLAVGGGSVIDGTKFVAAASLFEGDAWNILLK
EEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCEECCHHHHHHHHHHCCCCEEEEEE
GGSNIHRALPFGSVLTLPATGSEMNKGAVVTRKSLHAKLPFHSEHVFPQFSVLDPTKSYT
CCCCHHHHCCCCCEEEECCCCCCCCCCEEEEEHHHHEECCCCCCCCCCCCEECCCCCCCC
LPPRQVANGVVDAFVHIVEQYLTYPADAPVQDRFAEGLLQTLIEIGPQALAEPEHYQVRA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCHHHHCCCCCEEEEH
NLMWVATLALNGLIGSGVPQDWATHMLGHELTALHGLDHAQTLAIVLPTMLAERKEAKRD
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
KLVQYAQRVWAINEGSDEQKADLAIEKTRDFFEGLGVKTRLADYQLAAEHIEPLIDSLEA
HHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
HGMTALGEHNDVTPEVCRRVLHASL
CCCEECCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MNNFDFYNPTRIAFGEGKIAALDTLVPANANVLILFGGESARRTGTLTEVEAALGDRRVQ
CCCCCCCCCCEEEECCCCEEEEEEECCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCEEE
LFGGIEPNPSFETLMEAVSVVQRDGIDYLLAVGGGSVIDGTKFVAAASLFEGDAWNILLK
EEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCEECCHHHHHHHHHHCCCCEEEEEE
GGSNIHRALPFGSVLTLPATGSEMNKGAVVTRKSLHAKLPFHSEHVFPQFSVLDPTKSYT
CCCCHHHHCCCCCEEEECCCCCCCCCCEEEEEHHHHEECCCCCCCCCCCCEECCCCCCCC
LPPRQVANGVVDAFVHIVEQYLTYPADAPVQDRFAEGLLQTLIEIGPQALAEPEHYQVRA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCHHHHCCCCCEEEEH
NLMWVATLALNGLIGSGVPQDWATHMLGHELTALHGLDHAQTLAIVLPTMLAERKEAKRD
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
KLVQYAQRVWAINEGSDEQKADLAIEKTRDFFEGLGVKTRLADYQLAAEHIEPLIDSLEA
HHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
HGMTALGEHNDVTPEVCRRVLHASL
CCCEECCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]