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The map label for this gene is dhmA [H]

Identifier: 110835276

GI number: 110835276

Start: 2734484

End: 2735374

Strand: Direct

Name: dhmA [H]

Synonym: ABO_2415

Alternate gene names: 110835276

Gene position: 2734484-2735374 (Clockwise)

Preceding gene: 110835275

Following gene: 110835279

Centisome position: 87.64

GC content: 56.9

Gene sequence:

>891_bases
ATGGATTACTTGCGCACCCCAGATTCCCGCTTCGAGCGATTGCTCGACTACCCTTTCGAGCCAAACTACGTAACCGTGGA
CGGGCTGCGCATGCATTACGTGGATGAGGGGCCAGCCGACGGCAAGCCCATTCTGATGCTGCATGGGGAACCAACGTGGT
CCTATCTATATCGGCACATGATTCCGATTTGTGCGGCGGCGGGCCACCGGGTGATCGCCCCGGACTTGATCGGTTTCGGT
AAATCCGACAAGCCAACGGATATCAATGCTTATAGTTACCAAAACCACATGGACTGGGTTAAGTCCTTACTCGACCAGCT
TGAGCTCACCGAAATCACCTTAGTGTGCCAGGACTGGGGCTCACTGATTGGGCTGCGGATGGCCGCGGAGAACGAATCCC
GATTCCGCGCTATTGTGGTGGGTAACGGCATGCTGCCCACCGGAGACGAGCAGGCCCCAAAGGCGTTCCATATTTGGAAA
GCGTTCGCGATCCACAGCCCGGTACTGCCAATTTCCCGCATTCTCAATGTCGCCACTTTCCGCAAACTCGGCCCCGACGA
AATCCGTGCCTACGAGGCGCCATTCCCCAATAGAAAATACAAAACCGCCGCACGTGCTTTTCCCAAGCTGGTGCCGGTGA
CACCGAACGACCCGGCCACGCAAGCTAACCGTGCAGCGTGGAAGGCGTTGGAGCAATGGAAAAAGCCGTTCTTAACGACC
TTCAGCAACGGCGACCCGATTACCCGCGGAGGGGATAAATACATGCAAGAACGCATTCCCGGCGCCCAGGGGCAACCACA
CCAAACCCTGGTGGGCGGACATTTCTTGCAGGAGGATTCGCCGGTGCAGTTTGCCCAAGCCGTGAATAATTTGCTGGCAG
GCATGGACTAA

Upstream 100 bases:

>100_bases
GGGGCGCCCCTTCCTAGGGATTGGGTTCAACCGATGTGCGCTTAAGGCCCAGCATTCACGGCGCTTTTTAGCGGCGCCTT
AATAGCAAAAAGGATCGACC

Downstream 100 bases:

>100_bases
TTAAGGCTACCGCGGCATCAAATGGAGGGGGTGCCCGCCCGCGCGCCCCCTCTTTTGGGCGATCAGGCGGCTTGCCTGCT
ATGTCGGATTACCTCGCTAG

Product: haloalkane dehalogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MDYLRTPDSRFERLLDYPFEPNYVTVDGLRMHYVDEGPADGKPILMLHGEPTWSYLYRHMIPICAAAGHRVIAPDLIGFG
KSDKPTDINAYSYQNHMDWVKSLLDQLELTEITLVCQDWGSLIGLRMAAENESRFRAIVVGNGMLPTGDEQAPKAFHIWK
AFAIHSPVLPISRILNVATFRKLGPDEIRAYEAPFPNRKYKTAARAFPKLVPVTPNDPATQANRAAWKALEQWKKPFLTT
FSNGDPITRGGDKYMQERIPGAQGQPHQTLVGGHFLQEDSPVQFAQAVNNLLAGMD

Sequences:

>Translated_296_residues
MDYLRTPDSRFERLLDYPFEPNYVTVDGLRMHYVDEGPADGKPILMLHGEPTWSYLYRHMIPICAAAGHRVIAPDLIGFG
KSDKPTDINAYSYQNHMDWVKSLLDQLELTEITLVCQDWGSLIGLRMAAENESRFRAIVVGNGMLPTGDEQAPKAFHIWK
AFAIHSPVLPISRILNVATFRKLGPDEIRAYEAPFPNRKYKTAARAFPKLVPVTPNDPATQANRAAWKALEQWKKPFLTT
FSNGDPITRGGDKYMQERIPGAQGQPHQTLVGGHFLQEDSPVQFAQAVNNLLAGMD
>Mature_296_residues
MDYLRTPDSRFERLLDYPFEPNYVTVDGLRMHYVDEGPADGKPILMLHGEPTWSYLYRHMIPICAAAGHRVIAPDLIGFG
KSDKPTDINAYSYQNHMDWVKSLLDQLELTEITLVCQDWGSLIGLRMAAENESRFRAIVVGNGMLPTGDEQAPKAFHIWK
AFAIHSPVLPISRILNVATFRKLGPDEIRAYEAPFPNRKYKTAARAFPKLVPVTPNDPATQANRAAWKALEQWKKPFLTT
FSNGDPITRGGDKYMQERIPGAQGQPHQTLVGGHFLQEDSPVQFAQAVNNLLAGMD

Specific function: Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the haloalkane dehalogenase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI27597073, Length=121, Percent_Identity=34.7107438016529, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI218777840, Length=210, Percent_Identity=29.0476190476191, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI13376164, Length=210, Percent_Identity=29.0476190476191, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562298, Length=120, Percent_Identity=34.1666666666667, Blast_Score=89, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6324392, Length=117, Percent_Identity=37.6068376068376, Blast_Score=82, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.8.1.5 [H]

Molecular weight: Translated: 33274; Mature: 33274

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYLRTPDSRFERLLDYPFEPNYVTVDGLRMHYVDEGPADGKPILMLHGEPTWSYLYRHM
CCCCCCCHHHHHHHHCCCCCCCEEEECCEEEEEECCCCCCCCCEEEEECCCHHHHHHHHH
IPICAAAGHRVIAPDLIGFGKSDKPTDINAYSYQNHMDWVKSLLDQLELTEITLVCQDWG
HHHHHHCCCEEECHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLIGLRMAAENESRFRAIVVGNGMLPTGDEQAPKAFHIWKAFAIHSPVLPISRILNVATF
HHHEEHHCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
RKLGPDEIRAYEAPFPNRKYKTAARAFPKLVPVTPNDPATQANRAAWKALEQWKKPFLTT
HHCCHHHHHEECCCCCCCHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHHCCCCEEE
FSNGDPITRGGDKYMQERIPGAQGQPHQTLVGGHFLQEDSPVQFAQAVNNLLAGMD
CCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDYLRTPDSRFERLLDYPFEPNYVTVDGLRMHYVDEGPADGKPILMLHGEPTWSYLYRHM
CCCCCCCHHHHHHHHCCCCCCCEEEECCEEEEEECCCCCCCCCEEEEECCCHHHHHHHHH
IPICAAAGHRVIAPDLIGFGKSDKPTDINAYSYQNHMDWVKSLLDQLELTEITLVCQDWG
HHHHHHCCCEEECHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLIGLRMAAENESRFRAIVVGNGMLPTGDEQAPKAFHIWKAFAIHSPVLPISRILNVATF
HHHEEHHCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
RKLGPDEIRAYEAPFPNRKYKTAARAFPKLVPVTPNDPATQANRAAWKALEQWKKPFLTT
HHCCHHHHHEECCCCCCCHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHHCCCCEEE
FSNGDPITRGGDKYMQERIPGAQGQPHQTLVGGHFLQEDSPVQFAQAVNNLLAGMD
CCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA