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The map label for this gene is rfaE

Identifier: 110835151

GI number: 110835151

Start: 2611095

End: 2612525

Strand: Reverse

Name: rfaE

Synonym: ABO_2290

Alternate gene names: 110835151

Gene position: 2612525-2611095 (Counterclockwise)

Preceding gene: 110835154

Following gene: 110835148

Centisome position: 83.73

GC content: 59.75

Gene sequence:

>1431_bases
ATGCAAAACCCGCACATCCCTTCTTTTGCCCAAGCCCGTGTTCTGGTGGCGGGTGATGTCATGCTGGATCGCTATTGGCA
CGGCCCCACCAGCCGTATTTCACCGGAGGCGCCAGTGCCTGTGGTGCGCGTGACCGAGCTAGAAGATCGCCCTGGTGGTG
CCGCCAATGTGGCATTGAACATGGCCGCCTTGGGCGCCCGTGCAGAGCTGGTTGGGGTGACGGGCCGGGATGAAGCTGCC
TCGATTCTGGAAGAGCGGCTGGCGGCGGCGGAAGTGGGCTGCCATTTCCAGAAAGTGGACGGGTTGCCCACGATTACCAA
ATTGCGGGTGATTAGTCGTCAGCAACAACTGTTGCGGCTGGATTTTGAAGAAGCGTTCCACAGCCAGGACCCGGCGCCGT
TTGCCGAGCAGGTTAAGCAGCAGTTAGTCCATTGCGGTGCGCTGGTGTTGTCGGATTATGCCAAAGGCGCCCTGCGTGAC
TGTCCTGGTCTGATCGCCCTGGCCCGCGAAGCGGGGGTGCCGGTGCTGGTGGATCCCAAGGGTACCGATTTTGAGCCCTA
TCGCGGGGCGACCTTGCTGACGCCGAACCTGAGTGAGTTTGAAGCGGTGGTGGGCGTGGTGAAAGATGAGCAGGACCTGA
TTGCCAAGGGCCAGCAGCTGATCCGCGATCTGGACCTGCAGGCCATGCTGGTCACTCGCAGTGAAAAGGGCATGACCCTG
CTGCGTGATGGCTTGCCGGAGCTGCACTTGCCGGCCCGTGCCCGTGAAGTATTCGATGTCACTGGCGCGGGGGACACGGT
GATCTCGGTGCTGGCGGTGTCGTTAGCTGCGGGCGCCGCCATGGAAGATGCGGTGGCCTTGGCCAACATTGCCGCTGGCA
TTGTGGTGGCGAAACTGGGCACGGCGGTGGTCTCCGCTCCCGAATTGCGTCGTGCGGTGCATCAAGAGGGGGGCTCCGGT
CGTGGCGTGATGAGCGAAGCGCAATTGCTGATTGCCATCGAGGATGCTCGCGCCCAGGGCGAGAGAATCGTTTTCACCAA
TGGCTGTTTCGACATTATCCATGCCGGTCATGTGGGGTATTTGGATACGGCTCGTCGGCAAGGGGACCGCTTGGTGCTTG
CGGTAAACGGTGATGAATCGATTCGACGGTTGAAGGGGCCGGGTCGGCCTATTAATCCGCTTGAGCGCCGCATGGCAGTC
TTGGCTGCGTTGGAGGCGGTGGACTGGGTGGTGGCTTTCGATACTGATACACCGGAGCCACTGTTGGAGTCCATTAAGCC
AGATGTTCTTGTGAAAGGCGGTGACTACAGCGTAGACCAGGTGGTGGGCCACGAATTTGTGAAAAGCTATGGTGGTGAGG
TAAAAGTGCTCGATTTCATCGATGACATCTCCACCACCAAGATTGTGGAGCGCATTCGAGAGAAAGATTAA

Upstream 100 bases:

>100_bases
CGCAGTCTTGTGGCGCGAAGTGTACTGTCTGAACCGGTTTGCCTCCACTGCTATGCTACAATTGCGGGCAATTCGGCTCT
GTTGTCTTTTGGAGACATTG

Downstream 100 bases:

>100_bases
CGGATTCGCGGGGGGAGAATGAATTACTAGCGAGTGAACACTTGCCGGTTGCTCGCGTGTTCAGTGCGGCTGTGGAGATG
TCGAGTTGCCCGGCCTCTGC

Product: bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase

Products: NA

Alternate protein names: D-beta-D-heptose 7-phosphate kinase; D-beta-D-heptose 7-phosphotransferase; D-beta-D-heptose 1-phosphate adenosyltransferase

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MQNPHIPSFAQARVLVAGDVMLDRYWHGPTSRISPEAPVPVVRVTELEDRPGGAANVALNMAALGARAELVGVTGRDEAA
SILEERLAAAEVGCHFQKVDGLPTITKLRVISRQQQLLRLDFEEAFHSQDPAPFAEQVKQQLVHCGALVLSDYAKGALRD
CPGLIALAREAGVPVLVDPKGTDFEPYRGATLLTPNLSEFEAVVGVVKDEQDLIAKGQQLIRDLDLQAMLVTRSEKGMTL
LRDGLPELHLPARAREVFDVTGAGDTVISVLAVSLAAGAAMEDAVALANIAAGIVVAKLGTAVVSAPELRRAVHQEGGSG
RGVMSEAQLLIAIEDARAQGERIVFTNGCFDIIHAGHVGYLDTARRQGDRLVLAVNGDESIRRLKGPGRPINPLERRMAV
LAALEAVDWVVAFDTDTPEPLLESIKPDVLVKGGDYSVDQVVGHEFVKSYGGEVKVLDFIDDISTTKIVERIREKD

Sequences:

>Translated_476_residues
MQNPHIPSFAQARVLVAGDVMLDRYWHGPTSRISPEAPVPVVRVTELEDRPGGAANVALNMAALGARAELVGVTGRDEAA
SILEERLAAAEVGCHFQKVDGLPTITKLRVISRQQQLLRLDFEEAFHSQDPAPFAEQVKQQLVHCGALVLSDYAKGALRD
CPGLIALAREAGVPVLVDPKGTDFEPYRGATLLTPNLSEFEAVVGVVKDEQDLIAKGQQLIRDLDLQAMLVTRSEKGMTL
LRDGLPELHLPARAREVFDVTGAGDTVISVLAVSLAAGAAMEDAVALANIAAGIVVAKLGTAVVSAPELRRAVHQEGGSG
RGVMSEAQLLIAIEDARAQGERIVFTNGCFDIIHAGHVGYLDTARRQGDRLVLAVNGDESIRRLKGPGRPINPLERRMAV
LAALEAVDWVVAFDTDTPEPLLESIKPDVLVKGGDYSVDQVVGHEFVKSYGGEVKVLDFIDDISTTKIVERIREKD
>Mature_476_residues
MQNPHIPSFAQARVLVAGDVMLDRYWHGPTSRISPEAPVPVVRVTELEDRPGGAANVALNMAALGARAELVGVTGRDEAA
SILEERLAAAEVGCHFQKVDGLPTITKLRVISRQQQLLRLDFEEAFHSQDPAPFAEQVKQQLVHCGALVLSDYAKGALRD
CPGLIALAREAGVPVLVDPKGTDFEPYRGATLLTPNLSEFEAVVGVVKDEQDLIAKGQQLIRDLDLQAMLVTRSEKGMTL
LRDGLPELHLPARAREVFDVTGAGDTVISVLAVSLAAGAAMEDAVALANIAAGIVVAKLGTAVVSAPELRRAVHQEGGSG
RGVMSEAQLLIAIEDARAQGERIVFTNGCFDIIHAGHVGYLDTARRQGDRLVLAVNGDESIRRLKGPGRPINPLERRMAV
LAALEAVDWVVAFDTDTPEPLLESIKPDVLVKGGDYSVDQVVGHEFVKSYGGEVKVLDFIDDISTTKIVERIREKD

Specific function: Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose

COG id: COG2870

COG function: function code M; ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the cytidylyltransferase family

Homologues:

Organism=Escherichia coli, GI1789432, Length=469, Percent_Identity=61.1940298507463, Blast_Score=579, Evalue=1e-166,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HLDE_ALCBS (Q0VM60)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_694010.1
- ProteinModelPortal:   Q0VM60
- SMR:   Q0VM60
- STRING:   Q0VM60
- GeneID:   4212039
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_2290
- NMPDR:   fig|393595.12.peg.2293
- eggNOG:   COG2870
- HOGENOM:   HBG545535
- OMA:   LTPNRKE
- PhylomeDB:   Q0VM60
- ProtClustDB:   PRK11316
- BioCyc:   ABOR393595:ABO_2290-MONOMER
- HAMAP:   MF_01603
- InterPro:   IPR023030
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR011913
- InterPro:   IPR011914
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- TIGRFAMs:   TIGR00125
- TIGRFAMs:   TIGR02198
- TIGRFAMs:   TIGR02199

Pfam domain/function: PF01467 CTP_transf_2; PF00294 PfkB

EC number: 2.7.-.-

Molecular weight: Translated: 51124; Mature: 51124

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS00583 PFKB_KINASES_1; PS00584 PFKB_KINASES_2

Important sites: ACT_SITE 265-265

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNPHIPSFAQARVLVAGDVMLDRYWHGPTSRISPEAPVPVVRVTELEDRPGGAANVALN
CCCCCCCCHHHCEEEEECHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHEEE
MAALGARAELVGVTGRDEAASILEERLAAAEVGCHFQKVDGLPTITKLRVISRQQQLLRL
HHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHH
DFEEAFHSQDPAPFAEQVKQQLVHCGALVLSDYAKGALRDCPGLIALAREAGVPVLVDPK
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEECCC
GTDFEPYRGATLLTPNLSEFEAVVGVVKDEQDLIAKGQQLIRDLDLQAMLVTRSEKGMTL
CCCCCCCCCCEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCHH
LRDGLPELHLPARAREVFDVTGAGDTVISVLAVSLAAGAAMEDAVALANIAAGIVVAKLG
HHCCCCCCCCCHHHHHHEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
TAVVSAPELRRAVHQEGGSGRGVMSEAQLLIAIEDARAQGERIVFTNGCFDIIHAGHVGY
HHHHCCHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCEEEEECCCHHHHHCCCCCH
LDTARRQGDRLVLAVNGDESIRRLKGPGRPINPLERRMAVLAALEAVDWVVAFDTDTPEP
HHHHHCCCCEEEEEECCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCEEEEECCCCCHH
LLESIKPDVLVKGGDYSVDQVVGHEFVKSYGGEVKVLDFIDDISTTKIVERIREKD
HHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCCEEEEEHHHCCHHHHHHHHHHCCC
>Mature Secondary Structure
MQNPHIPSFAQARVLVAGDVMLDRYWHGPTSRISPEAPVPVVRVTELEDRPGGAANVALN
CCCCCCCCHHHCEEEEECHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHEEE
MAALGARAELVGVTGRDEAASILEERLAAAEVGCHFQKVDGLPTITKLRVISRQQQLLRL
HHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHH
DFEEAFHSQDPAPFAEQVKQQLVHCGALVLSDYAKGALRDCPGLIALAREAGVPVLVDPK
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEECCC
GTDFEPYRGATLLTPNLSEFEAVVGVVKDEQDLIAKGQQLIRDLDLQAMLVTRSEKGMTL
CCCCCCCCCCEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCHH
LRDGLPELHLPARAREVFDVTGAGDTVISVLAVSLAAGAAMEDAVALANIAAGIVVAKLG
HHCCCCCCCCCHHHHHHEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
TAVVSAPELRRAVHQEGGSGRGVMSEAQLLIAIEDARAQGERIVFTNGCFDIIHAGHVGY
HHHHCCHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCEEEEECCCHHHHHCCCCCH
LDTARRQGDRLVLAVNGDESIRRLKGPGRPINPLERRMAVLAALEAVDWVVAFDTDTPEP
HHHHHCCCCEEEEEECCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCEEEEECCCCCHH
LLESIKPDVLVKGGDYSVDQVVGHEFVKSYGGEVKVLDFIDDISTTKIVERIREKD
HHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCCEEEEEHHHCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA