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The map label for this gene is grx [H]

Identifier: 110835134

GI number: 110835134

Start: 2593530

End: 2593790

Strand: Reverse

Name: grx [H]

Synonym: ABO_2273

Alternate gene names: 110835134

Gene position: 2593790-2593530 (Counterclockwise)

Preceding gene: 110835135

Following gene: 110835133

Centisome position: 83.13

GC content: 56.32

Gene sequence:

>261_bases
ATGGCCAGAGTCGAGCTGTATACCACCTCTTGGTGCCCGTTTTGCGTGCGTGCCAAGCAGTTACTTAACAGCAAGAATGT
GGCGTTTGAGGATACCGATGTGGATCGTGAGCCCCAGCAACGTGCAGTCATGATGCAGCGTGGCGGTGGCCGGACGGTGC
CGCAGATTTTCATTAATGATCACGCCGTCGGTGGCTGTGATGAACTTTTTGCTCTAGAGCGAGCGGGGGCGCTCGATGCT
CTGCTCGGAGCGGATCAGTAA

Upstream 100 bases:

>100_bases
CGAACCAAGGGGTTTTCCGACCTGTATCGCATTCAGGGTGGCTTGAATGCATGGCGTTCAGCGAGCCTGCCGGTAGTCAA
AGCGTAAGCAGGAGACAAGG

Downstream 100 bases:

>100_bases
CAGGAGAAGAATATGGCTGATGAACAGCAACAGGTTTTCCAACTGCAGCGTATCTACCTCAAAGACACCTCGTTCGAGTG
CCCGGGGGCACCGGAAGTGT

Product: glutaredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 86; Mature: 85

Protein sequence:

>86_residues
MARVELYTTSWCPFCVRAKQLLNSKNVAFEDTDVDREPQQRAVMMQRGGGRTVPQIFINDHAVGGCDELFALERAGALDA
LLGADQ

Sequences:

>Translated_86_residues
MARVELYTTSWCPFCVRAKQLLNSKNVAFEDTDVDREPQQRAVMMQRGGGRTVPQIFINDHAVGGCDELFALERAGALDA
LLGADQ
>Mature_85_residues
ARVELYTTSWCPFCVRAKQLLNSKNVAFEDTDVDREPQQRAVMMQRGGGRTVPQIFINDHAVGGCDELFALERAGALDAL
LGADQ

Specific function: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins [H]

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=82, Percent_Identity=51.219512195122, Blast_Score=93, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 9514; Mature: 9383

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARVELYTTSWCPFCVRAKQLLNSKNVAFEDTDVDREPQQRAVMMQRGGGRTVPQIFIND
CCEEEEEECCCCHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHHHHCCCCCCCCEEEECC
HAVGGCDELFALERAGALDALLGADQ
CCCCCHHHHHHHHHCCCHHHHCCCCC
>Mature Secondary Structure 
ARVELYTTSWCPFCVRAKQLLNSKNVAFEDTDVDREPQQRAVMMQRGGGRTVPQIFIND
CEEEEEECCCCHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHHHHCCCCCCCCEEEECC
HAVGGCDELFALERAGALDALLGADQ
CCCCCHHHHHHHHHCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]