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The map label for this gene is gcp

Identifier: 110834920

GI number: 110834920

Start: 2346014

End: 2347051

Strand: Reverse

Name: gcp

Synonym: ABO_2059

Alternate gene names: 110834920

Gene position: 2347051-2346014 (Counterclockwise)

Preceding gene: 110834927

Following gene: 110834918

Centisome position: 75.22

GC content: 59.25

Gene sequence:

>1038_bases
ATGCGCGTATTGGGTATTGAATCGAGCTGCGACGAAACCGGCGTGGCTATCTATGACACCGAGCAGGGGCTATTGGGGCA
GGCCTTATATAGCCAAGTAGAGATGCATGCTCGCTATGGCGGTGTGGTGCCGGAGCTGGCCAGCCGTGATCATGTGCAGC
GGGTGCTGCCATTGATACGCGAAGTCATGACGGAGGCTAATACCCAACCGCAACAGTTGGATGGGGTGGCGTTTACCGCT
GGCCCTGGGCTGGCCGGCGCTTTGCTGGTAGGGGCGGGTGTGGCCCGTTCGTTGGCGTTTGGCTGGAATTTGCCTGCGGT
GGCCGTGCACCACATGGAGGGGCACCTGCTGGCGCCCTTGCTGGAGCCTAATGCCCCTGCGTTTCCCTTTGTGGCGCTGC
TGGTTAGCGGGGGCCACACACTGCTGTTGGACGCTAAGGCCCTGGGGGAATATGAGATTTTAGGTGAATCAGTGGATGAT
GCGGCTGGAGAGGCGTTTGATAAAGCCGCAAAAATGATGGGCTTGGGTTACCCCGGTGGCCCCCGTGTTGCGACGTTGGC
GCAACAGGGTACGGCAGGTCGGTTCCGTTTTCCGCGCCCGATGACCGATCGTCCAGGCTTGGATATGAGCTTTTCTGGGC
TCAAGACTTTCACGTTAAATACCATCAATGATTTGGGCGGAAAAGAAGCGTTAAGTGAGCAGGACCGGGCGGATATTGCT
CGTGCGTTCGAAGAAGCGGCGGTGGATACCTTGGTGATCAAGTGCCGCCGTGCGGTGGAGCAGACCGGCCACAAGCGATT
GGTGATGGCTGGAGGGGTCAGTGCGAATCAGTCGTTGCGTGCTAAGTTGGCGGAACAGATGAAAAAACGGGGTGTGGACG
TTTATTACCCCGCGCCTCAATACTGCACGGATAACGGTGCCATGATCGCTTTTGCGGGAGCCCTGCGGTTGCAGGCCGGG
GAACGGGCCGAGCTACCCATCAAGATCCGCCCGCGCTGGCCGCTGACGGAACTGGCGAAGCTGCAAGGCGCGGATTAA

Upstream 100 bases:

>100_bases
CGGGGTGCGGCGAGGCGGGGATTCTACCCTAGTGGTGAGGAAATGCAAATCCTACGGTTCATCGCTATCATGGCAACGCA
ATTTCACAGGGTTGATCACC

Downstream 100 bases:

>100_bases
GTTCGGTTTACTCTCAGTAAGCTCAGCCCGGCGCCCTAGGGGGACGCTGGTGGTGTGTCTCAGAAATCATCACGTTTTGC
CGTGTTGGAACGTGTAGCTA

Product: glycoprotease family protein

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MRVLGIESSCDETGVAIYDTEQGLLGQALYSQVEMHARYGGVVPELASRDHVQRVLPLIREVMTEANTQPQQLDGVAFTA
GPGLAGALLVGAGVARSLAFGWNLPAVAVHHMEGHLLAPLLEPNAPAFPFVALLVSGGHTLLLDAKALGEYEILGESVDD
AAGEAFDKAAKMMGLGYPGGPRVATLAQQGTAGRFRFPRPMTDRPGLDMSFSGLKTFTLNTINDLGGKEALSEQDRADIA
RAFEEAAVDTLVIKCRRAVEQTGHKRLVMAGGVSANQSLRAKLAEQMKKRGVDVYYPAPQYCTDNGAMIAFAGALRLQAG
ERAELPIKIRPRWPLTELAKLQGAD

Sequences:

>Translated_345_residues
MRVLGIESSCDETGVAIYDTEQGLLGQALYSQVEMHARYGGVVPELASRDHVQRVLPLIREVMTEANTQPQQLDGVAFTA
GPGLAGALLVGAGVARSLAFGWNLPAVAVHHMEGHLLAPLLEPNAPAFPFVALLVSGGHTLLLDAKALGEYEILGESVDD
AAGEAFDKAAKMMGLGYPGGPRVATLAQQGTAGRFRFPRPMTDRPGLDMSFSGLKTFTLNTINDLGGKEALSEQDRADIA
RAFEEAAVDTLVIKCRRAVEQTGHKRLVMAGGVSANQSLRAKLAEQMKKRGVDVYYPAPQYCTDNGAMIAFAGALRLQAG
ERAELPIKIRPRWPLTELAKLQGAD
>Mature_345_residues
MRVLGIESSCDETGVAIYDTEQGLLGQALYSQVEMHARYGGVVPELASRDHVQRVLPLIREVMTEANTQPQQLDGVAFTA
GPGLAGALLVGAGVARSLAFGWNLPAVAVHHMEGHLLAPLLEPNAPAFPFVALLVSGGHTLLLDAKALGEYEILGESVDD
AAGEAFDKAAKMMGLGYPGGPRVATLAQQGTAGRFRFPRPMTDRPGLDMSFSGLKTFTLNTINDLGGKEALSEQDRADIA
RAFEEAAVDTLVIKCRRAVEQTGHKRLVMAGGVSANQSLRAKLAEQMKKRGVDVYYPAPQYCTDNGAMIAFAGALRLQAG
ERAELPIKIRPRWPLTELAKLQGAD

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=339, Percent_Identity=34.2182890855457, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI8923380, Length=326, Percent_Identity=31.9018404907975, Blast_Score=137, Evalue=1e-32,
Organism=Escherichia coli, GI1789445, Length=338, Percent_Identity=68.6390532544379, Blast_Score=489, Evalue=1e-139,
Organism=Caenorhabditis elegans, GI17557464, Length=329, Percent_Identity=32.5227963525836, Blast_Score=168, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI71995670, Length=328, Percent_Identity=32.0121951219512, Blast_Score=133, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6320099, Length=376, Percent_Identity=32.1808510638298, Blast_Score=181, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6322891, Length=350, Percent_Identity=27.4285714285714, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI20129063, Length=338, Percent_Identity=34.6153846153846, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI21357207, Length=332, Percent_Identity=31.3253012048193, Blast_Score=141, Evalue=7e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_ALCBS (Q0VMU1)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_693779.1
- ProteinModelPortal:   Q0VMU1
- SMR:   Q0VMU1
- STRING:   Q0VMU1
- MEROPS:   M22.001
- GeneID:   4211688
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_2059
- NMPDR:   fig|393595.12.peg.2061
- eggNOG:   COG0533
- HOGENOM:   HBG304663
- OMA:   PAVGVHH
- PhylomeDB:   Q0VMU1
- BioCyc:   ABOR393595:ABO_2059-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 36829; Mature: 36829

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLGIESSCDETGVAIYDTEQGLLGQALYSQVEMHARYGGVVPELASRDHVQRVLPLIR
CEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
EVMTEANTQPQQLDGVAFTAGPGLAGALLVGAGVARSLAFGWNLPAVAVHHMEGHLLAPL
HHHHHCCCCCHHHCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHEEECCCCCEECCC
LEPNAPAFPFVALLVSGGHTLLLDAKALGEYEILGESVDDAAGEAFDKAAKMMGLGYPGG
CCCCCCHHHHHHHHHCCCCEEEEEHHHCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC
PRVATLAQQGTAGRFRFPRPMTDRPGLDMSFSGLKTFTLNTINDLGGKEALSEQDRADIA
CCEEEHHCCCCCCCEECCCCCCCCCCCCCCCCCCEEEEEHHHHHCCCHHHHHHHHHHHHH
RAFEEAAVDTLVIKCRRAVEQTGHKRLVMAGGVSANQSLRAKLAEQMKKRGVDVYYPAPQ
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCC
YCTDNGAMIAFAGALRLQAGERAELPIKIRPRWPLTELAKLQGAD
CCCCCCCEEEEEEEHHCCCCCCCCCCEEECCCCCHHHHHHHCCCC
>Mature Secondary Structure
MRVLGIESSCDETGVAIYDTEQGLLGQALYSQVEMHARYGGVVPELASRDHVQRVLPLIR
CEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
EVMTEANTQPQQLDGVAFTAGPGLAGALLVGAGVARSLAFGWNLPAVAVHHMEGHLLAPL
HHHHHCCCCCHHHCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHEEECCCCCEECCC
LEPNAPAFPFVALLVSGGHTLLLDAKALGEYEILGESVDDAAGEAFDKAAKMMGLGYPGG
CCCCCCHHHHHHHHHCCCCEEEEEHHHCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC
PRVATLAQQGTAGRFRFPRPMTDRPGLDMSFSGLKTFTLNTINDLGGKEALSEQDRADIA
CCEEEHHCCCCCCCEECCCCCCCCCCCCCCCCCCEEEEEHHHHHCCCHHHHHHHHHHHHH
RAFEEAAVDTLVIKCRRAVEQTGHKRLVMAGGVSANQSLRAKLAEQMKKRGVDVYYPAPQ
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCC
YCTDNGAMIAFAGALRLQAGERAELPIKIRPRWPLTELAKLQGAD
CCCCCCCEEEEEEEHHCCCCCCCCCCEEECCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA