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The map label for this gene is cyoB [H]

Identifier: 110834897

GI number: 110834897

Start: 2322461

End: 2324470

Strand: Reverse

Name: cyoB [H]

Synonym: ABO_2036

Alternate gene names: 110834897

Gene position: 2324470-2322461 (Counterclockwise)

Preceding gene: 110834898

Following gene: 110834896

Centisome position: 74.5

GC content: 54.23

Gene sequence:

>2010_bases
GTGCCGCCCATGTTTGAGAACCTGGATCTGATCAAACTGATCTTTGGTCGCCTTACCTGGGAGGCAATCCCCTTCCATGA
TCCGATCATCCTCAGCACCTTTGCCATGGTGGCGCTGGGGGGAGTCGCGGTGCTGGCGGCGCTGACGCGCTATAAGCTGT
GGGGCTACCTGTGGAATGAATGGTTCACTACCATCGACCACAAGAAAATCGGCATCATGTACATCATCCTTGGCTTGGTA
ATGCTGCTGCGCGGCTTCGCTGATGCGATCATGATGCGCCTTCATCAAGCGATGGCCTTTGGTGATGCCACCGGCTATCT
GCCGCCTCACCACTACGATCAGATCTTCACCGCCCATGGCGTGATCATGATTTTTTTCGTGGCCATGCCACTGGTGACCG
GGATCATGAATTATCTGATTCCGTTGCAAATCGGCACCCGCGATGTGGCTTTCCCGTTTCTGAATAATTTCAGTTTTTGG
ATGACTACCGGTGGTGCTGTACTGCTGATGGTGTCTCTGTTTGTGGGTGAGTTTGCTAAGACGGGTTGGCTGGCCTATCC
GCCGTTATCGGGCATTTTGCAGAGCCCTGGGGTGGGGGTGGACTACTACATCTGGGCGTTGCAGATTGCCGGGGTGGGGA
CGCTGTTATCCGGGGTTAACCTGTTGGTGACCATCGTCAAGATGCGGGCCCCGGGCATGAGCCTGATGAAGATGCCGGTG
TTCACCTGGACCTCCCTGTGCACCAATATCTTGATTGTGGCGGCGTTCCCGGTACTCACTGCAGTGCTGGCCATGCTGTC
GATGGATCGCTACCTGGACACGGCTTTCTTCACCAATGATCTTGGTGGCAACGCCATGATGTATGTGAATTTGATCTGGA
TCTGGGGGCACCCCGAGGTGTACATCCTGATTTTGCCGGTGTTCGGTATTTTCTCGGAGATCGTGTCTACCTATAGCCGC
AAGCCGCTGTTCGGTTACACCTCTATGGTTTATGCGACCGTGGTAATTACCGTGCTGTCGTACTTGGTGTGGCTGCACCA
TTTCTTCACCATGGGGTCGGGGGCCAGTGTGAATTCGTTCTTCGGTATTACCACGATGATTATCTCGATACCGACCGGTG
CGAAGATATTCAACTGGTTGTTCACCATGTTCCGTGGCCGGATCAGGTTCGACGTGCCCATGCTATGGACCTTGGGCTTT
ATGGTGACCTTTGTTATTGGTGGCATGACTGGGGTGCTGCTGGCGGTGCCGCCGGTGGATTTCGTGCTGCATAACAGCCT
GTTTCTGATTGCCCACTTCCATAACGTGATTATTGGCGGGGTGCTGTTCGGCCTGTTCGCGGGTATCACTTATTGGTTCC
CCAAAGCCACCGGTTACAAGCTGGATGAATTCTGGGGCAAGATGTCCTTCTGGTTCTGGCTGATTGGTTTCTACTTCGCC
TTTATGCCGTTGTACGTACTCGGTTTGATGGGCGTAACCCGTCGTGTCAGCCACTTTGAAGATATGTCCTTGCAGATCTG
GTTTCAGATAGCCGCCTTTGGTGCGGTGTTGATCGCCGTGGGGATCGCGTCTTTCATCATTCAGCTGGTGGTGAGCTTTA
TGCGCCGCGAGTCACTCAAGGACGAAACCGGAGATCCATGGGATGGCCGCACCCTAGAGTGGTCCACCTCGTCACCTCCC
CCTCCCTACAACTTTGCGTTCACTCCGCGAGTGCATCAGTTAGACGCTTGGTGGCAGATGAAACAGCATGGCTTCCAGCG
TCCTGAGTCCGGCTTTATTGCGATTCATATGCCCAAGGGCACCTGGGCGGGCATTGTGCTCTCGGGTATCAGTGTTGCCA
TCGGCTTTGCCATGATTTGGCACATGTGGCTGCTGGCTGGCGTATCTTTTGTGGCGCTGATCGGCACAGTGATCTATCAC
ACCTTCAATTACGACCGGGAGTACTACATTCCGGCGGAAGAAATAGAGCGGATTGAAGCAGAACGTACACGGGTGCTTGC
CAATGTCTGA

Upstream 100 bases:

>100_bases
AGGCTAACCATGAAGGTCATCAAGATCACGAAGGTAATGCCGGCCACCCGCACCATGGAGGCCACCATGAATAAATTTTT
CCTGATCGCAAACGCAGTAG

Downstream 100 bases:

>100_bases
TAACACCATGACGGCTAACGCGAACAGCACGCACGATGGCCAGCTGGAGTTTCTGGTAAAGGGGGATCATCACCCCCAGA
ACGGAACCTTGCTGGGTTTC

Product: cytochrome c oxidase subunit I

Products: NA

Alternate protein names: Cytochrome o subunit 1; Cytochrome o ubiquinol oxidase subunit 1; Oxidase BO(3) subunit 1; Ubiquinol oxidase chain A; Ubiquinol oxidase polypeptide I [H]

Number of amino acids: Translated: 669; Mature: 668

Protein sequence:

>669_residues
MPPMFENLDLIKLIFGRLTWEAIPFHDPIILSTFAMVALGGVAVLAALTRYKLWGYLWNEWFTTIDHKKIGIMYIILGLV
MLLRGFADAIMMRLHQAMAFGDATGYLPPHHYDQIFTAHGVIMIFFVAMPLVTGIMNYLIPLQIGTRDVAFPFLNNFSFW
MTTGGAVLLMVSLFVGEFAKTGWLAYPPLSGILQSPGVGVDYYIWALQIAGVGTLLSGVNLLVTIVKMRAPGMSLMKMPV
FTWTSLCTNILIVAAFPVLTAVLAMLSMDRYLDTAFFTNDLGGNAMMYVNLIWIWGHPEVYILILPVFGIFSEIVSTYSR
KPLFGYTSMVYATVVITVLSYLVWLHHFFTMGSGASVNSFFGITTMIISIPTGAKIFNWLFTMFRGRIRFDVPMLWTLGF
MVTFVIGGMTGVLLAVPPVDFVLHNSLFLIAHFHNVIIGGVLFGLFAGITYWFPKATGYKLDEFWGKMSFWFWLIGFYFA
FMPLYVLGLMGVTRRVSHFEDMSLQIWFQIAAFGAVLIAVGIASFIIQLVVSFMRRESLKDETGDPWDGRTLEWSTSSPP
PPYNFAFTPRVHQLDAWWQMKQHGFQRPESGFIAIHMPKGTWAGIVLSGISVAIGFAMIWHMWLLAGVSFVALIGTVIYH
TFNYDREYYIPAEEIERIEAERTRVLANV

Sequences:

>Translated_669_residues
MPPMFENLDLIKLIFGRLTWEAIPFHDPIILSTFAMVALGGVAVLAALTRYKLWGYLWNEWFTTIDHKKIGIMYIILGLV
MLLRGFADAIMMRLHQAMAFGDATGYLPPHHYDQIFTAHGVIMIFFVAMPLVTGIMNYLIPLQIGTRDVAFPFLNNFSFW
MTTGGAVLLMVSLFVGEFAKTGWLAYPPLSGILQSPGVGVDYYIWALQIAGVGTLLSGVNLLVTIVKMRAPGMSLMKMPV
FTWTSLCTNILIVAAFPVLTAVLAMLSMDRYLDTAFFTNDLGGNAMMYVNLIWIWGHPEVYILILPVFGIFSEIVSTYSR
KPLFGYTSMVYATVVITVLSYLVWLHHFFTMGSGASVNSFFGITTMIISIPTGAKIFNWLFTMFRGRIRFDVPMLWTLGF
MVTFVIGGMTGVLLAVPPVDFVLHNSLFLIAHFHNVIIGGVLFGLFAGITYWFPKATGYKLDEFWGKMSFWFWLIGFYFA
FMPLYVLGLMGVTRRVSHFEDMSLQIWFQIAAFGAVLIAVGIASFIIQLVVSFMRRESLKDETGDPWDGRTLEWSTSSPP
PPYNFAFTPRVHQLDAWWQMKQHGFQRPESGFIAIHMPKGTWAGIVLSGISVAIGFAMIWHMWLLAGVSFVALIGTVIYH
TFNYDREYYIPAEEIERIEAERTRVLANV
>Mature_668_residues
PPMFENLDLIKLIFGRLTWEAIPFHDPIILSTFAMVALGGVAVLAALTRYKLWGYLWNEWFTTIDHKKIGIMYIILGLVM
LLRGFADAIMMRLHQAMAFGDATGYLPPHHYDQIFTAHGVIMIFFVAMPLVTGIMNYLIPLQIGTRDVAFPFLNNFSFWM
TTGGAVLLMVSLFVGEFAKTGWLAYPPLSGILQSPGVGVDYYIWALQIAGVGTLLSGVNLLVTIVKMRAPGMSLMKMPVF
TWTSLCTNILIVAAFPVLTAVLAMLSMDRYLDTAFFTNDLGGNAMMYVNLIWIWGHPEVYILILPVFGIFSEIVSTYSRK
PLFGYTSMVYATVVITVLSYLVWLHHFFTMGSGASVNSFFGITTMIISIPTGAKIFNWLFTMFRGRIRFDVPMLWTLGFM
VTFVIGGMTGVLLAVPPVDFVLHNSLFLIAHFHNVIIGGVLFGLFAGITYWFPKATGYKLDEFWGKMSFWFWLIGFYFAF
MPLYVLGLMGVTRRVSHFEDMSLQIWFQIAAFGAVLIAVGIASFIIQLVVSFMRRESLKDETGDPWDGRTLEWSTSSPPP
PYNFAFTPRVHQLDAWWQMKQHGFQRPESGFIAIHMPKGTWAGIVLSGISVAIGFAMIWHMWLLAGVSFVALIGTVIYHT
FNYDREYYIPAEEIERIEAERTRVLANV

Specific function: Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain that predominates when cells are grown at high aeration. This ubiquinol oxidase shows proton pump activity across the membrane in addition to the electron transfer [H]

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=511, Percent_Identity=39.3346379647749, Blast_Score=339, Evalue=5e-93,
Organism=Escherichia coli, GI1786634, Length=651, Percent_Identity=65.8986175115207, Blast_Score=896, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6226519, Length=539, Percent_Identity=38.404452690167, Blast_Score=347, Evalue=2e-96,
Organism=Saccharomyces cerevisiae, GI6226524, Length=330, Percent_Identity=43.6363636363636, Blast_Score=252, Evalue=1e-67,
Organism=Saccharomyces cerevisiae, GI6226523, Length=251, Percent_Identity=35.4581673306773, Blast_Score=140, Evalue=8e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014207 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: 1.10.3.-

Molecular weight: Translated: 75509; Mature: 75377

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPMFENLDLIKLIFGRLTWEAIPFHDPIILSTFAMVALGGVAVLAALTRYKLWGYLWNE
CCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WFTTIDHKKIGIMYIILGLVMLLRGFADAIMMRLHQAMAFGDATGYLPPHHYDQIFTAHG
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
VIMIFFVAMPLVTGIMNYLIPLQIGTRDVAFPFLNNFSFWMTTGGAVLLMVSLFVGEFAK
HHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHH
TGWLAYPPLSGILQSPGVGVDYYIWALQIAGVGTLLSGVNLLVTIVKMRAPGMSLMKMPV
CCCEECCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
FTWTSLCTNILIVAAFPVLTAVLAMLSMDRYLDTAFFTNDLGGNAMMYVNLIWIWGHPEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCE
YILILPVFGIFSEIVSTYSRKPLFGYTSMVYATVVITVLSYLVWLHHFFTMGSGASVNSF
EEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
FGITTMIISIPTGAKIFNWLFTMFRGRIRFDVPMLWTLGFMVTFVIGGMTGVLLAVPPVD
HHHHHHEEECCCCHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCHH
FVLHNSLFLIAHFHNVIIGGVLFGLFAGITYWFPKATGYKLDEFWGKMSFWFWLIGFYFA
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
FMPLYVLGLMGVTRRVSHFEDMSLQIWFQIAAFGAVLIAVGIASFIIQLVVSFMRRESLK
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DETGDPWDGRTLEWSTSSPPPPYNFAFTPRVHQLDAWWQMKQHGFQRPESGFIAIHMPKG
CCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCC
TWAGIVLSGISVAIGFAMIWHMWLLAGVSFVALIGTVIYHTFNYDREYYIPAEEIERIEA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHH
ERTRVLANV
HHHHHHCCC
>Mature Secondary Structure 
PPMFENLDLIKLIFGRLTWEAIPFHDPIILSTFAMVALGGVAVLAALTRYKLWGYLWNE
CCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WFTTIDHKKIGIMYIILGLVMLLRGFADAIMMRLHQAMAFGDATGYLPPHHYDQIFTAHG
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
VIMIFFVAMPLVTGIMNYLIPLQIGTRDVAFPFLNNFSFWMTTGGAVLLMVSLFVGEFAK
HHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHH
TGWLAYPPLSGILQSPGVGVDYYIWALQIAGVGTLLSGVNLLVTIVKMRAPGMSLMKMPV
CCCEECCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
FTWTSLCTNILIVAAFPVLTAVLAMLSMDRYLDTAFFTNDLGGNAMMYVNLIWIWGHPEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCE
YILILPVFGIFSEIVSTYSRKPLFGYTSMVYATVVITVLSYLVWLHHFFTMGSGASVNSF
EEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
FGITTMIISIPTGAKIFNWLFTMFRGRIRFDVPMLWTLGFMVTFVIGGMTGVLLAVPPVD
HHHHHHEEECCCCHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCHH
FVLHNSLFLIAHFHNVIIGGVLFGLFAGITYWFPKATGYKLDEFWGKMSFWFWLIGFYFA
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
FMPLYVLGLMGVTRRVSHFEDMSLQIWFQIAAFGAVLIAVGIASFIIQLVVSFMRRESLK
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DETGDPWDGRTLEWSTSSPPPPYNFAFTPRVHQLDAWWQMKQHGFQRPESGFIAIHMPKG
CCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCC
TWAGIVLSGISVAIGFAMIWHMWLLAGVSFVALIGTVIYHTFNYDREYYIPAEEIERIEA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHH
ERTRVLANV
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Protoheme IX (Heme B55 and B562); Copper B. [C]

Metal ions: Fe; Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]