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The map label for this gene is dsbD [H]

Identifier: 110834868

GI number: 110834868

Start: 2292579

End: 2294459

Strand: Direct

Name: dsbD [H]

Synonym: ABO_2007

Alternate gene names: 110834868

Gene position: 2292579-2294459 (Clockwise)

Preceding gene: 110834857

Following gene: 110834869

Centisome position: 73.48

GC content: 56.62

Gene sequence:

>1881_bases
ATGCATACAAGCTGGCAACGACTGGGGCTTGCTCTATTAATGCTATTTACAGTGTCCACAGCCATTGCGCAGGATCTATT
CGGCGACCAAGAACGCCTGCCCACCGTGGATGAAGCCATTCAGCTAGTACCTGATGCCGACTGGGACAACCAGCAACTGC
GACTGGATTTCGAGCTGATCGATGATGTTTATCTCTATCAACACCGTTTCGGGTTCACCCTACGTGACACCAACGGCAAT
GTGATTAACGACTTTGCCGAACTGATACTGCCCCCCGGGAAGCCCAAAACCGACGAGATATTCGGTGATGTAGAAGTCTA
TTTCGACCGTTTGAAGTTCTCGCTTCCTTTGAATAGCGTGCCGCTAGTGGATACCGAACTGGAAGTACGCTATCAAGGCT
GCATTGAAGATACTCTCTGCTACCCGCCCACCCGCAAAGTGTTTGCATTCGACAATCCGCAACCGGCAAAAAAGCCCATG
GCCGCGGTGCCACCCGCGGCCACTGACTCCACCGCCGGCCCGGGTTTTCTCGATACACTACGGTCTGAGGACGCCAACGC
CTTCAACCAGTGGATGAACGAACAACCCCTTGGTTTAATCATCGGCCTCTTCTTTGTGGGCGGGCTGCTGCTGGCCTTTA
CCCCCTGCGTGTTTCCCATGGTCCCCATTCTCTCCGGTATCATTGCCGGCGAGAAAGAGCCCAGCGCCACACGGGGCTTT
ACTCTCAGTGTCAGCTATGTGTTGGGTATGGCCGTGCCGTACACTTTGGCAGGCTTATTGGTGGCACTTTTTGGCGCCGG
CCTGAACCTGCAATTCATGCTGCAACAACCCGCGGCCATCATTACTTCAGTAGCGGTATTTGTCGTACTGGCCCTGTCCA
TGTTTGGTCTGTATGAACTGCAGCTACCTGCGGCCTTGCGTAACAAGCTCCATCAACCTGGCCAAGAAGCCCGCGGCAGC
CTGATCGGCGCCGCCATCATGGGCACCATTTCGGCCTTGGTCGTCTCCCCTTGTGTTACCCCCATCCTAGCCGGCGCGTT
GATCTATGTTGCCGCTAGTGGCGACGCGGCCACCGGCGCGGCTTCCCTGTTCGCCCTATCGATTGGCATGGGCCTACCAT
TGATTATCTTTGGCACCGGTGGCGGCAGCTTGCTTCCCCGTGCTGGCATGTGGATGGAAGAGATCAAACGGTTCTTCGGC
GTAGTGATGCTAGGCGTCGCCATCTGGCTGCTGGACCGCATCATCAGTGACACTATTACCCTTGGCCTCTATGGCTTGTT
GTTAACCGTGTATGGCATCCAGCTGGGGGCATTGGAGCCTGCCGGTGAAGGCGCTGCCCGGCTCAAGCGGGGCTTGGCTC
TGGTACTGGCTCTGTACGGGGCGGTGATGATTGTCGGCGCCTTGAGTGGCGGCAAGGACCCTCTGCAACCGTTAGCGCAG
ATGAATCAGCCAGCCACGAACAACGGCCCCCTCCACGTTAGCACCCCCTCCTCCCAGCCTGGCGATCATGGTCCCTGGCA
GACCATCGTTGGCAAGGCCTCCCTGGAGCAGGCACTGGCCACGTCTCGTCAAGCCAACAAGCCCGTGCTGGTAGATTTCT
TCGCTGAGTGGTGCGTGGCTTGCAAGGTCCTGGAAGAGACCACATTGAGTCACCCGGATGTGCTTAATGCCATGCTCGGC
TTTGACCTCTACCGGGTGGATATCACCGAAATCAACGCCGACAGCCAGGCCATCATGGAGCAGTACAACATTCTTGGGTT
GCCGGCACTGGTGTTTTTCACCCCCATAAGCACTGAAATTCCCGATTCAAGAGTCCTCGGCGAAATGGGGCCACAACGGT
TTATTGAACACCTTAACAAGCGGGTCCTGCCTAGGCTTTAA

Upstream 100 bases:

>100_bases
AACCTTAAGGCACTGTTAATAATCTGCCCTGAAACTTATCGGCTATCCTGGCATCCAAGCGATGCCACCATTTTTGGGTT
CGGGGTTTGAGGAGAAAGGA

Downstream 100 bases:

>100_bases
TGCCGCGCCAATATAGAAAGGGGCGCGCGCGCGCCCTTCGCTGCAAACGCCCCGCGGGTCACGCTCCTACCGCGAGCGGT
TGCGCCTCCCACCTAAGCAA

Product: thiol:disulfide interchange protein DsbD

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 626; Mature: 626

Protein sequence:

>626_residues
MHTSWQRLGLALLMLFTVSTAIAQDLFGDQERLPTVDEAIQLVPDADWDNQQLRLDFELIDDVYLYQHRFGFTLRDTNGN
VINDFAELILPPGKPKTDEIFGDVEVYFDRLKFSLPLNSVPLVDTELEVRYQGCIEDTLCYPPTRKVFAFDNPQPAKKPM
AAVPPAATDSTAGPGFLDTLRSEDANAFNQWMNEQPLGLIIGLFFVGGLLLAFTPCVFPMVPILSGIIAGEKEPSATRGF
TLSVSYVLGMAVPYTLAGLLVALFGAGLNLQFMLQQPAAIITSVAVFVVLALSMFGLYELQLPAALRNKLHQPGQEARGS
LIGAAIMGTISALVVSPCVTPILAGALIYVAASGDAATGAASLFALSIGMGLPLIIFGTGGGSLLPRAGMWMEEIKRFFG
VVMLGVAIWLLDRIISDTITLGLYGLLLTVYGIQLGALEPAGEGAARLKRGLALVLALYGAVMIVGALSGGKDPLQPLAQ
MNQPATNNGPLHVSTPSSQPGDHGPWQTIVGKASLEQALATSRQANKPVLVDFFAEWCVACKVLEETTLSHPDVLNAMLG
FDLYRVDITEINADSQAIMEQYNILGLPALVFFTPISTEIPDSRVLGEMGPQRFIEHLNKRVLPRL

Sequences:

>Translated_626_residues
MHTSWQRLGLALLMLFTVSTAIAQDLFGDQERLPTVDEAIQLVPDADWDNQQLRLDFELIDDVYLYQHRFGFTLRDTNGN
VINDFAELILPPGKPKTDEIFGDVEVYFDRLKFSLPLNSVPLVDTELEVRYQGCIEDTLCYPPTRKVFAFDNPQPAKKPM
AAVPPAATDSTAGPGFLDTLRSEDANAFNQWMNEQPLGLIIGLFFVGGLLLAFTPCVFPMVPILSGIIAGEKEPSATRGF
TLSVSYVLGMAVPYTLAGLLVALFGAGLNLQFMLQQPAAIITSVAVFVVLALSMFGLYELQLPAALRNKLHQPGQEARGS
LIGAAIMGTISALVVSPCVTPILAGALIYVAASGDAATGAASLFALSIGMGLPLIIFGTGGGSLLPRAGMWMEEIKRFFG
VVMLGVAIWLLDRIISDTITLGLYGLLLTVYGIQLGALEPAGEGAARLKRGLALVLALYGAVMIVGALSGGKDPLQPLAQ
MNQPATNNGPLHVSTPSSQPGDHGPWQTIVGKASLEQALATSRQANKPVLVDFFAEWCVACKVLEETTLSHPDVLNAMLG
FDLYRVDITEINADSQAIMEQYNILGLPALVFFTPISTEIPDSRVLGEMGPQRFIEHLNKRVLPRL
>Mature_626_residues
MHTSWQRLGLALLMLFTVSTAIAQDLFGDQERLPTVDEAIQLVPDADWDNQQLRLDFELIDDVYLYQHRFGFTLRDTNGN
VINDFAELILPPGKPKTDEIFGDVEVYFDRLKFSLPLNSVPLVDTELEVRYQGCIEDTLCYPPTRKVFAFDNPQPAKKPM
AAVPPAATDSTAGPGFLDTLRSEDANAFNQWMNEQPLGLIIGLFFVGGLLLAFTPCVFPMVPILSGIIAGEKEPSATRGF
TLSVSYVLGMAVPYTLAGLLVALFGAGLNLQFMLQQPAAIITSVAVFVVLALSMFGLYELQLPAALRNKLHQPGQEARGS
LIGAAIMGTISALVVSPCVTPILAGALIYVAASGDAATGAASLFALSIGMGLPLIIFGTGGGSLLPRAGMWMEEIKRFFG
VVMLGVAIWLLDRIISDTITLGLYGLLLTVYGIQLGALEPAGEGAARLKRGLALVLALYGAVMIVGALSGGKDPLQPLAQ
MNQPATNNGPLHVSTPSSQPGDHGPWQTIVGKASLEQALATSRQANKPVLVDFFAEWCVACKVLEETTLSHPDVLNAMLG
FDLYRVDITEINADSQAIMEQYNILGLPALVFFTPISTEIPDSRVLGEMGPQRFIEHLNKRVLPRL

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=622, Percent_Identity=32.9581993569132, Blast_Score=290, Evalue=1e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 67441; Mature: 67441

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTSWQRLGLALLMLFTVSTAIAQDLFGDQERLPTVDEAIQLVPDADWDNQQLRLDFELI
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHCCCCCCCCCEEEEHHHHH
DDVYLYQHRFGFTLRDTNGNVINDFAELILPPGKPKTDEIFGDVEVYFDRLKFSLPLNSV
HHHHHHHHHCCCEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
PLVDTELEVRYQGCIEDTLCYPPTRKVFAFDNPQPAKKPMAAVPPAATDSTAGPGFLDTL
CCCCCHHHHHHHCCHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
RSEDANAFNQWMNEQPLGLIIGLFFVGGLLLAFTPCVFPMVPILSGIIAGEKEPSATRGF
HCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCE
TLSVSYVLGMAVPYTLAGLLVALFGAGLNLQFMLQQPAAIITSVAVFVVLALSMFGLYEL
EEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHCHHHHHHHHHHHHHHHHHHHHHHHE
QLPAALRNKLHQPGQEARGSLIGAAIMGTISALVVSPCVTPILAGALIYVAASGDAATGA
ECCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHH
ASLFALSIGMGLPLIIFGTGGGSLLPRAGMWMEEIKRFFGVVMLGVAIWLLDRIISDTIT
HHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLYGLLLTVYGIQLGALEPAGEGAARLKRGLALVLALYGAVMIVGALSGGKDPLQPLAQ
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
MNQPATNNGPLHVSTPSSQPGDHGPWQTIVGKASLEQALATSRQANKPVLVDFFAEWCVA
CCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
CKVLEETTLSHPDVLNAMLGFDLYRVDITEINADSQAIMEQYNILGLPALVFFTPISTEI
HHHHHHHCCCCHHHHHHHHCCEEEEEEEEEECCCHHHHHHHHHHCCCCHHHHCCCCCCCC
PDSRVLGEMGPQRFIEHLNKRVLPRL
CCHHHHHHCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MHTSWQRLGLALLMLFTVSTAIAQDLFGDQERLPTVDEAIQLVPDADWDNQQLRLDFELI
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHCCCCCCCCCEEEEHHHHH
DDVYLYQHRFGFTLRDTNGNVINDFAELILPPGKPKTDEIFGDVEVYFDRLKFSLPLNSV
HHHHHHHHHCCCEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
PLVDTELEVRYQGCIEDTLCYPPTRKVFAFDNPQPAKKPMAAVPPAATDSTAGPGFLDTL
CCCCCHHHHHHHCCHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
RSEDANAFNQWMNEQPLGLIIGLFFVGGLLLAFTPCVFPMVPILSGIIAGEKEPSATRGF
HCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCE
TLSVSYVLGMAVPYTLAGLLVALFGAGLNLQFMLQQPAAIITSVAVFVVLALSMFGLYEL
EEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHCHHHHHHHHHHHHHHHHHHHHHHHE
QLPAALRNKLHQPGQEARGSLIGAAIMGTISALVVSPCVTPILAGALIYVAASGDAATGA
ECCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHH
ASLFALSIGMGLPLIIFGTGGGSLLPRAGMWMEEIKRFFGVVMLGVAIWLLDRIISDTIT
HHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLYGLLLTVYGIQLGALEPAGEGAARLKRGLALVLALYGAVMIVGALSGGKDPLQPLAQ
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
MNQPATNNGPLHVSTPSSQPGDHGPWQTIVGKASLEQALATSRQANKPVLVDFFAEWCVA
CCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
CKVLEETTLSHPDVLNAMLGFDLYRVDITEINADSQAIMEQYNILGLPALVFFTPISTEI
HHHHHHHCCCCHHHHHHHHCCEEEEEEEEEECCCHHHHHHHHHHCCCCHHHHCCCCCCCC
PDSRVLGEMGPQRFIEHLNKRVLPRL
CCHHHHHHCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA