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The map label for this gene is livM [C]

Identifier: 110834844

GI number: 110834844

Start: 2267164

End: 2268306

Strand: Reverse

Name: livM [C]

Synonym: ABO_1983

Alternate gene names: 110834844

Gene position: 2268306-2267164 (Counterclockwise)

Preceding gene: 110834845

Following gene: 110834843

Centisome position: 72.7

GC content: 52.41

Gene sequence:

>1143_bases
ATGAAATCAACGTCGTTCTTTCAATGGTTAGGATCCCGCGAGGGAATCTACCATCTGCTGTTGGCGCTGCTGCTGGTGGT
GGTGTTCCCACTGGCGTTGGATGCCTTTCGTCTTAATATGGTTGGCAAGTATCTAACCTATGCGTTTGCCGCGCTAGGTC
TGGTTCTTTGCTGGGGCCGCAGTGGTATTTTGAGTCTTGGGCAGGGGATTTTTTTCGGCCTTGGCGGCTACTGCATGGCG
ATGTTCTTGAAGTTGGAAGCGTCCAGTCCAGAAAATACATCCATTCAGTCTACCCCGGGTATTCCTGATTTCATGGACTG
GAACCAGCTCACCGCACTGCCCTGGTTTTGGGAACCCTTCCACAGCTTTTCCTTTACTTTGATTGCGGTGGTTGCCGTGC
CGGCGATTCTTGCCCTTATCATTGGCGTAGCCATGTTCAAACGCCGAGTAGGTGGCGTGTATTTTGCCATCATTACTCAG
GCGATTGCCGCCATCCTGACGATCCTGATCATTGGTCAGCAGGGTTTCACAGGGGGGGTGAATGGTATTACCGATCTGCG
CACCTTGATGGGGTGGGATATCCGTAGTGACGAAGCCAAAACGGCGTTGTACTTCGTGTGTGTAGGCATGTTGTTCCTGT
GCCTGATGATTGGTCGCTGGGTCATGCATAGCAAGCTGGGGCGTATTCTGCTTGCCATGCGCGACCAGGAAGATCGGGTA
CGTTTTTCCGGTTACGACGTTGCTTCTTTCAAGATATTTGTGTTCTGCCTAGCCGCTATGTTTGCCGGTGTGGGTGGGGC
CATGTTTACCCTGCAGGTAGGTTTCATGTCGCCAACATTTGTGGGGATTGTACCCTCCATTGAAATGGTGGTGCTGTGTG
CCGTGGGCGGCCGGAATTCTCTGCTGGGCGCGGTGTATGGCGCGTTAATTGTGAATGCCGCTAAAACGGGCTTCTCAGAA
TCCTTCCCTGAACTGTGGCTGTATGCAATGGGTGCTCTATTCATTGGTGTAGTGCTGGCCTTCCCTGATGGCTTGGCTGG
ACTTTATAACCGTTATATTCAGCCGCTAGAAAATAAGTTGCCCTCGCTGCTGCGTCGCCGTCGCGCTGATGCTGAAAATC
TGCCTGTGGAGGAAGTGAAATGA

Upstream 100 bases:

>100_bases
TTCAATGGCTAAAGTGCTCACGCTGCTGGTTGTGGTCGGCATTCTGATGTTGCGTCCGCAAGGTTTGTTTGCACTCAAGG
TTCGTCGCTAGGAGATCGCC

Downstream 100 bases:

>100_bases
TGCCGACTAATAATGATTTCATTCTTGCGGTAGAAGGTTTGACTGTTTCTTTCGATGGGTTCAAGGCGGTTAACGATATG
TCGCTGTACCTGGAACCACA

Product: branched-chain amino acid ABC transporter permease

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: Inner-Membrane Translocator; Branched-Chain Amino Acid ABC Transporter Permease Protein; ABC Transporter Permease Protein; Urea ABC Transporter Permease UrtC; Amino Acid Or Sugar ABC Transport System Permease Protein; Branched Chain Amino Acid ABC Transporter Permease; ABC Transporter ; Branched-Chain Amino Acid Transport System Permease Protein; Branched-Chain Amino Acid ABC Transporter Permease; ABC Transporter Membrane Protein; ABC Transporter Permease; ABC Transporter; Urea ABC Transporter Permease; Permease Of ABC Transporter; ABC Transporter Membrane Spanning Protein; Urea Or Short-Chain Amide ABC Transporter Permease Protein; Amide-Urea Transport System Permease Protein; Branched Chain Amino Acid ABC Transporter Permease Protein; Amide-Urea Transporter Permease Protein; Transmembrane Component Of ABC Transporter; High-Affinity Branched-Chain Amino Acid Transport System; Urea/Short Chain-Amide ABC Transporter Permease Protein; Urea ABC Transporter Permease Protein; ABC Transporter Related Protein; Branched-Chain Amino Acid Transporter; Urea Transport System Permease Protein; ABC Transporter Inner-Membrane Translocator; ABC-Type Transport System Permease Protein; ABC Transporter-Like Protein; Integral Membrane Protein; Urea ABC Transporter Inner-Membrane Subunit UrtC; ABC Branched Amino Acid Transporter Permease Component; ABC-Type Branched-Chain Amino Acid Transport System; Branched-Chain Amino Acid Transport System Permease; Permease Protein Of ABC Transporter; Urea Transport System Permease Component Protein; Permease Component Of ABC Transporter; Urea Or Short-Chain Amide ABC Transporter; Permease Transporter Transmembrane Protein; Urea ABC Transport Permease Component UrtC

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MKSTSFFQWLGSREGIYHLLLALLLVVVFPLALDAFRLNMVGKYLTYAFAALGLVLCWGRSGILSLGQGIFFGLGGYCMA
MFLKLEASSPENTSIQSTPGIPDFMDWNQLTALPWFWEPFHSFSFTLIAVVAVPAILALIIGVAMFKRRVGGVYFAIITQ
AIAAILTILIIGQQGFTGGVNGITDLRTLMGWDIRSDEAKTALYFVCVGMLFLCLMIGRWVMHSKLGRILLAMRDQEDRV
RFSGYDVASFKIFVFCLAAMFAGVGGAMFTLQVGFMSPTFVGIVPSIEMVVLCAVGGRNSLLGAVYGALIVNAAKTGFSE
SFPELWLYAMGALFIGVVLAFPDGLAGLYNRYIQPLENKLPSLLRRRRADAENLPVEEVK

Sequences:

>Translated_380_residues
MKSTSFFQWLGSREGIYHLLLALLLVVVFPLALDAFRLNMVGKYLTYAFAALGLVLCWGRSGILSLGQGIFFGLGGYCMA
MFLKLEASSPENTSIQSTPGIPDFMDWNQLTALPWFWEPFHSFSFTLIAVVAVPAILALIIGVAMFKRRVGGVYFAIITQ
AIAAILTILIIGQQGFTGGVNGITDLRTLMGWDIRSDEAKTALYFVCVGMLFLCLMIGRWVMHSKLGRILLAMRDQEDRV
RFSGYDVASFKIFVFCLAAMFAGVGGAMFTLQVGFMSPTFVGIVPSIEMVVLCAVGGRNSLLGAVYGALIVNAAKTGFSE
SFPELWLYAMGALFIGVVLAFPDGLAGLYNRYIQPLENKLPSLLRRRRADAENLPVEEVK
>Mature_380_residues
MKSTSFFQWLGSREGIYHLLLALLLVVVFPLALDAFRLNMVGKYLTYAFAALGLVLCWGRSGILSLGQGIFFGLGGYCMA
MFLKLEASSPENTSIQSTPGIPDFMDWNQLTALPWFWEPFHSFSFTLIAVVAVPAILALIIGVAMFKRRVGGVYFAIITQ
AIAAILTILIIGQQGFTGGVNGITDLRTLMGWDIRSDEAKTALYFVCVGMLFLCLMIGRWVMHSKLGRILLAMRDQEDRV
RFSGYDVASFKIFVFCLAAMFAGVGGAMFTLQVGFMSPTFVGIVPSIEMVVLCAVGGRNSLLGAVYGALIVNAAKTGFSE
SFPELWLYAMGALFIGVVLAFPDGLAGLYNRYIQPLENKLPSLLRRRRADAENLPVEEVK

Specific function: Part Of The Binding-Protein-Dependent Transport System For Branched-Chain Amino Acids. Probably Responsible For The Translocation Of The Substrates Across The Membrane. [C]

COG id: COG4177

COG function: function code E; ABC-type branched-chain amino acid transport system, permease component

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789865, Length=325, Percent_Identity=24.9230769230769, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 41653; Mature: 41653

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSTSFFQWLGSREGIYHLLLALLLVVVFPLALDAFRLNMVGKYLTYAFAALGLVLCWGR
CCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SGILSLGQGIFFGLGGYCMAMFLKLEASSPENTSIQSTPGIPDFMDWNQLTALPWFWEPF
CCHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHH
HSFSFTLIAVVAVPAILALIIGVAMFKRRVGGVYFAIITQAIAAILTILIIGQQGFTGGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
NGITDLRTLMGWDIRSDEAKTALYFVCVGMLFLCLMIGRWVMHSKLGRILLAMRDQEDRV
CHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
RFSGYDVASFKIFVFCLAAMFAGVGGAMFTLQVGFMSPTFVGIVPSIEMVVLCAVGGRNS
EECCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHCHHHHHHEEECCCCHH
LLGAVYGALIVNAAKTGFSESFPELWLYAMGALFIGVVLAFPDGLAGLYNRYIQPLENKL
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
PSLLRRRRADAENLPVEEVK
HHHHHHHHCCCCCCCHHCCC
>Mature Secondary Structure
MKSTSFFQWLGSREGIYHLLLALLLVVVFPLALDAFRLNMVGKYLTYAFAALGLVLCWGR
CCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SGILSLGQGIFFGLGGYCMAMFLKLEASSPENTSIQSTPGIPDFMDWNQLTALPWFWEPF
CCHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHH
HSFSFTLIAVVAVPAILALIIGVAMFKRRVGGVYFAIITQAIAAILTILIIGQQGFTGGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
NGITDLRTLMGWDIRSDEAKTALYFVCVGMLFLCLMIGRWVMHSKLGRILLAMRDQEDRV
CHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
RFSGYDVASFKIFVFCLAAMFAGVGGAMFTLQVGFMSPTFVGIVPSIEMVVLCAVGGRNS
EECCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHCHHHHHHEEECCCCHH
LLGAVYGALIVNAAKTGFSESFPELWLYAMGALFIGVVLAFPDGLAGLYNRYIQPLENKL
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
PSLLRRRRADAENLPVEEVK
HHHHHHHHCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA