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The map label for this gene is uahA [H]

Identifier: 110834753

GI number: 110834753

Start: 2165432

End: 2169019

Strand: Direct

Name: uahA [H]

Synonym: ABO_1892

Alternate gene names: 110834753

Gene position: 2165432-2169019 (Clockwise)

Preceding gene: 110834752

Following gene: 110834755

Centisome position: 69.4

GC content: 56.66

Gene sequence:

>3588_bases
ATGTTCAACAAGGTTTTGATTGCCAATCGCGGTGCCATTGCCACCCGCGTTACCCGTACCCTCCAATCCCTGGGCATCAC
TTCCATAGCGGTTTTTGCCGAGGCCGACCGCGATTCCCTGCACGTACGTTACGCCGATAAAGCCTTCTGCCTAGGGGAAG
GCAATGCCCAGGATACCTATCTGAATCAGGATAAGCTGTTTGCCCTCATGGAAGAACATGGCGTAGAAGCCGTGCACCCC
GGTTACGGTTTTCTCAGTGAAAACCCGGACTTTGTGAAGGGCTGTGAAGCCCGCGGCATTGCCTTTATTGGCCCAACGCC
CGAACAAATGGACACCTTCGGCCTCAAGCACACCGCTCGTGCCCTGGCAGAAAAAAACGATGTTCCTCTACTGCCAGGTA
CCGGCCTGCTGAATGATAAAGAGGCAGCACTGAAAGCGGCTGAAAAAATCCGTTATCCGGTCATGCTGAAGAGCACAGCC
GGCGGTGGCGGCATCGGCATGCAAATCTGTGACAATGCAGAAAACCTAGACAAGGCTTGGGATAGCGTGCGCCGCCTCAG
CGCCAACAATTTTTCCAATGATGGCGTCTTTATAGAAAAATATATCGCCCGCGCCCGTCACATTGAAGTCCAGGTATTCG
GTGATGGCAAAGGCCAAGCCGTTACCCTCGGTGAACGCGACTGTTCCGCCCAGCGTCGCCACCAGAAAGTGTTGGAAGAA
ACACCGGCCCCCAACCTGCCCGATCATGTTCGCCATGAACTGCACGATACTGCACGCACGCTTATGCAAGCGGTGCATTA
CCGCAATGCCGGCACAGTGGAATTCATTCTCGATCAGGACACCAACACTTTCTACTTTCTGGAAGTGAATACCCGCCTGC
AGGTGGAACACGGTGTCACCGAACAGATTTTCGGCGTGGATCTGGTGGAGTGGATGATCAAACTGGCCGCTGGCGAGCTG
CCCGCACTGAACTCACTCGGCCCCTTTACTCCCAATGGTCACGCCATTCAGGCGCGGATCTATGCCGAGGACCCGGCCAA
GGATTTCCAACCCAGCGCCGGCCTGCTGACTGCTGTCACCTTTCCTGAAGCAGATGGGCAAGCATTGCGTATTGATCACT
GGGTGGAAGCCGGGCTTACCGTTTCTCCCCTGTTCGATCCCATGCTAGCCAAGGTCATCATTCATCAAGCCGATCGCGAT
AGCGCACTGAACGCACTGGCGCAGACCCTGGATGGCATCACCCTGGAAGGTATTGAGACCAACCGGGAATATGTTCGCAC
CATTCTGGCCAACCCGGTATTTGCGCAAGGGCGAATGACCACCCGCTACCTCAATGATTTCCGTTACCGACCTTTTACCG
TAGATGTACTGGCCGGCGGCACCATGACCACAGTACAGGATTACCCTGGCCGGAGTGGCTACTGGCCCGTGGGCGTGCCC
CCTTCAGGACCTTTTGACAACCTCAGCTTCCGTCTCGGTAACCGCCTGCTGGGCAACGACGAAGCCGCCGCCGGACTGGA
ATTCACGCTTAACGGCCCAACGCTGAAATTCAACCAGGCCACCCGCATAGCCCTTACTGGCGCGGACATGCAGGCCTCTC
TGGATAGCCGTCCGGTCCCCCCTTATCAGGTCATCCAGGTACAACCAGGTCAGGTGCTAAAACTGGGCAAAGTAAGCGGC
GAAGGCGCTCGCGCCTATCTTGCTATTGCCAGCGGCATCCAGTGCACCCCCTATCTGGGCTCACGCAGTACTTTTACCCT
CGGCCAGTTCGGTGGTCACGGTGGCCGCGCCCTGCGCACCGGCGATGTGCTGCACTTTTCTGAAGATACAGGCATAACAG
CCCGCGTGGAGGTGCCGGCAAGCTTGAAGCCCGAGCTTGGCAAAGCCTGGACCCTGCGGGTGATCTATGGCCCCCATGGC
GCCCCGGACTTTTTTACCGACGACGACATGGCCATGTTTTTCTCCACGGACTGGCAAGTGCATTACAACTCCAGCCGGAC
CGGTATCCGCCTAGTGGGCCCCAAACCAAACTGGGCACGCAGTGATGGTGGCGAGGCCGGCATGCACCCTTCCAACATTC
ACGACAATGCTTATGCAGTGGGCACAGTGGACTTCACGGGCGACATGCCGGTCATCCTCGGCCCGGACGGGCCGTCACTG
GGTGGCTTTGTCTGCCCCGCCACTGTGGTACTGGCCGACCGCTGGAAGCTGGGCCAACTAAAAGCCGGCGATACCCTACG
TTTTGAAGCCATCAGCCTGGACGATGCGGATACACTTGCCGCCGAACAAGACCACTGCGTGTCCTCACTCGTTGAGCCGG
CTAAACGGGTAAAAAGTGCTGTCATTACCACACCGGTGCTTAATACCCTTAGCAAACAAGAAGCCGGCGTAGACGTGGTT
TACCGCGCCGCTGGAGACCGTTATCTACTGGTGGAATACGGCCCCCTAGTGCTGGATCTGCGCCTCCGATTTCGCGCCCA
TGCGCTCATGCTGTGGCTTGAACAGCAAAAACTCCCCGGCATTATTGAACTGACGCCCGGTATCCGCTCCTTGCAGATCC
ATTTCAATCCACAGGTTCTTACTCGCCAGCAACTGCTCAAAGACCTAGCCGGTGCCGAACATGCCCTACAGCAGCAGGAT
GATCTGGAAGTCCCTTCGCGCATCGTACATATCCCGCTAAGCTGGGATGACCAAGCCTGTCATCAAGCCATCGAAAAATA
CATCCAGTCGGTGCGCAAGGATGCCCCCTGGTGCCCGTCTAATCTGGAATTTATCCGTCGCATCAACGGGCTGGACAGCA
TTGATGCTGTAAAAAATATTCTGTTCAGCGCCAGCTACGTGGTGATGGGGTTGGGTGATGTCTACCTGGGTGCGCCAGTG
GCTACCCCCTACGACCCCCGCCATCGTCTGGTCACCACCAAGTACAACCCCGCCCGTACCTGGACGGCAGAAAACTCCGT
GGGCATCGGCGGCGCTTACCTGTGTGTGTACGGCATGGAAGGCCCCGGCGGTTATCAGTTTGTCGGCCGCACCCTGCAGA
TGTGGAACCGTTACCGCAAAACACGAGTATTCAACCAGCCCTGGCTACTGCGTTTCTTCGACCAGATTCGCTTTTACGAG
GTAAGCCACGAAGAACTTAACCAGATTCGCCGAGATTTCCCCAAGGGGGATTACCCGCTGAAGGTGGAAGAAACGACCTT
CAGCCTCAGTGCTTACCAGCAGTTCCTGGACGACAACCAACAGGATATTGCCACCTTCACCGACGTCCGCAATCAGGCCT
TTGATGAAGAACTGCAACGCTGGGTGGACAGTGGCCAGATCAATTTCCAGTCCGAGCAGAATCTAGAGGCAGACAATGGA
GCCGAAGAAGTGGATGGCACTCCAGTGGAATCCCCTGTAGCAGGCAACATTTGGAAACTGAACGTGTCCGAAGGCGACCA
CGTGCAAAAAGGTGACGTGGTGGCTGTGCTTGAATCCATGAAGATGGAAATCGAAATCTACGCCCCGGGCTCAGGAAACG
TCATCACTGTTTCCCGCCAGGAAGGTCAGCAGATCAATGCGGGGCAAGCGATCATGGTGCTGGATTGA

Upstream 100 bases:

>100_bases
GCACCGACCAATTTCCCTGGGGACGACCCCGGCGGCCAAGGCTATAAAGACGGGACGGCCCGTCATCTGTCCCAGAGACA
GCCCGACAAGAGAAAAAGTC

Downstream 100 bases:

>100_bases
AAGCCTGTTAAAGAGACTCTGAAAAACTGCAGCCTCTTGATCTGTCCAGAAAGGCCATAACAATATCGCCACCGTTGCTG
TTATTGCGATAGCAAGGATG

Product: urea carboxylase/allophanate hydrolase

Products: NA

Alternate protein names: Acetyl-CoA carboxylase subunit A; ACC [H]

Number of amino acids: Translated: 1195; Mature: 1195

Protein sequence:

>1195_residues
MFNKVLIANRGAIATRVTRTLQSLGITSIAVFAEADRDSLHVRYADKAFCLGEGNAQDTYLNQDKLFALMEEHGVEAVHP
GYGFLSENPDFVKGCEARGIAFIGPTPEQMDTFGLKHTARALAEKNDVPLLPGTGLLNDKEAALKAAEKIRYPVMLKSTA
GGGGIGMQICDNAENLDKAWDSVRRLSANNFSNDGVFIEKYIARARHIEVQVFGDGKGQAVTLGERDCSAQRRHQKVLEE
TPAPNLPDHVRHELHDTARTLMQAVHYRNAGTVEFILDQDTNTFYFLEVNTRLQVEHGVTEQIFGVDLVEWMIKLAAGEL
PALNSLGPFTPNGHAIQARIYAEDPAKDFQPSAGLLTAVTFPEADGQALRIDHWVEAGLTVSPLFDPMLAKVIIHQADRD
SALNALAQTLDGITLEGIETNREYVRTILANPVFAQGRMTTRYLNDFRYRPFTVDVLAGGTMTTVQDYPGRSGYWPVGVP
PSGPFDNLSFRLGNRLLGNDEAAAGLEFTLNGPTLKFNQATRIALTGADMQASLDSRPVPPYQVIQVQPGQVLKLGKVSG
EGARAYLAIASGIQCTPYLGSRSTFTLGQFGGHGGRALRTGDVLHFSEDTGITARVEVPASLKPELGKAWTLRVIYGPHG
APDFFTDDDMAMFFSTDWQVHYNSSRTGIRLVGPKPNWARSDGGEAGMHPSNIHDNAYAVGTVDFTGDMPVILGPDGPSL
GGFVCPATVVLADRWKLGQLKAGDTLRFEAISLDDADTLAAEQDHCVSSLVEPAKRVKSAVITTPVLNTLSKQEAGVDVV
YRAAGDRYLLVEYGPLVLDLRLRFRAHALMLWLEQQKLPGIIELTPGIRSLQIHFNPQVLTRQQLLKDLAGAEHALQQQD
DLEVPSRIVHIPLSWDDQACHQAIEKYIQSVRKDAPWCPSNLEFIRRINGLDSIDAVKNILFSASYVVMGLGDVYLGAPV
ATPYDPRHRLVTTKYNPARTWTAENSVGIGGAYLCVYGMEGPGGYQFVGRTLQMWNRYRKTRVFNQPWLLRFFDQIRFYE
VSHEELNQIRRDFPKGDYPLKVEETTFSLSAYQQFLDDNQQDIATFTDVRNQAFDEELQRWVDSGQINFQSEQNLEADNG
AEEVDGTPVESPVAGNIWKLNVSEGDHVQKGDVVAVLESMKMEIEIYAPGSGNVITVSRQEGQQINAGQAIMVLD

Sequences:

>Translated_1195_residues
MFNKVLIANRGAIATRVTRTLQSLGITSIAVFAEADRDSLHVRYADKAFCLGEGNAQDTYLNQDKLFALMEEHGVEAVHP
GYGFLSENPDFVKGCEARGIAFIGPTPEQMDTFGLKHTARALAEKNDVPLLPGTGLLNDKEAALKAAEKIRYPVMLKSTA
GGGGIGMQICDNAENLDKAWDSVRRLSANNFSNDGVFIEKYIARARHIEVQVFGDGKGQAVTLGERDCSAQRRHQKVLEE
TPAPNLPDHVRHELHDTARTLMQAVHYRNAGTVEFILDQDTNTFYFLEVNTRLQVEHGVTEQIFGVDLVEWMIKLAAGEL
PALNSLGPFTPNGHAIQARIYAEDPAKDFQPSAGLLTAVTFPEADGQALRIDHWVEAGLTVSPLFDPMLAKVIIHQADRD
SALNALAQTLDGITLEGIETNREYVRTILANPVFAQGRMTTRYLNDFRYRPFTVDVLAGGTMTTVQDYPGRSGYWPVGVP
PSGPFDNLSFRLGNRLLGNDEAAAGLEFTLNGPTLKFNQATRIALTGADMQASLDSRPVPPYQVIQVQPGQVLKLGKVSG
EGARAYLAIASGIQCTPYLGSRSTFTLGQFGGHGGRALRTGDVLHFSEDTGITARVEVPASLKPELGKAWTLRVIYGPHG
APDFFTDDDMAMFFSTDWQVHYNSSRTGIRLVGPKPNWARSDGGEAGMHPSNIHDNAYAVGTVDFTGDMPVILGPDGPSL
GGFVCPATVVLADRWKLGQLKAGDTLRFEAISLDDADTLAAEQDHCVSSLVEPAKRVKSAVITTPVLNTLSKQEAGVDVV
YRAAGDRYLLVEYGPLVLDLRLRFRAHALMLWLEQQKLPGIIELTPGIRSLQIHFNPQVLTRQQLLKDLAGAEHALQQQD
DLEVPSRIVHIPLSWDDQACHQAIEKYIQSVRKDAPWCPSNLEFIRRINGLDSIDAVKNILFSASYVVMGLGDVYLGAPV
ATPYDPRHRLVTTKYNPARTWTAENSVGIGGAYLCVYGMEGPGGYQFVGRTLQMWNRYRKTRVFNQPWLLRFFDQIRFYE
VSHEELNQIRRDFPKGDYPLKVEETTFSLSAYQQFLDDNQQDIATFTDVRNQAFDEELQRWVDSGQINFQSEQNLEADNG
AEEVDGTPVESPVAGNIWKLNVSEGDHVQKGDVVAVLESMKMEIEIYAPGSGNVITVSRQEGQQINAGQAIMVLD
>Mature_1195_residues
MFNKVLIANRGAIATRVTRTLQSLGITSIAVFAEADRDSLHVRYADKAFCLGEGNAQDTYLNQDKLFALMEEHGVEAVHP
GYGFLSENPDFVKGCEARGIAFIGPTPEQMDTFGLKHTARALAEKNDVPLLPGTGLLNDKEAALKAAEKIRYPVMLKSTA
GGGGIGMQICDNAENLDKAWDSVRRLSANNFSNDGVFIEKYIARARHIEVQVFGDGKGQAVTLGERDCSAQRRHQKVLEE
TPAPNLPDHVRHELHDTARTLMQAVHYRNAGTVEFILDQDTNTFYFLEVNTRLQVEHGVTEQIFGVDLVEWMIKLAAGEL
PALNSLGPFTPNGHAIQARIYAEDPAKDFQPSAGLLTAVTFPEADGQALRIDHWVEAGLTVSPLFDPMLAKVIIHQADRD
SALNALAQTLDGITLEGIETNREYVRTILANPVFAQGRMTTRYLNDFRYRPFTVDVLAGGTMTTVQDYPGRSGYWPVGVP
PSGPFDNLSFRLGNRLLGNDEAAAGLEFTLNGPTLKFNQATRIALTGADMQASLDSRPVPPYQVIQVQPGQVLKLGKVSG
EGARAYLAIASGIQCTPYLGSRSTFTLGQFGGHGGRALRTGDVLHFSEDTGITARVEVPASLKPELGKAWTLRVIYGPHG
APDFFTDDDMAMFFSTDWQVHYNSSRTGIRLVGPKPNWARSDGGEAGMHPSNIHDNAYAVGTVDFTGDMPVILGPDGPSL
GGFVCPATVVLADRWKLGQLKAGDTLRFEAISLDDADTLAAEQDHCVSSLVEPAKRVKSAVITTPVLNTLSKQEAGVDVV
YRAAGDRYLLVEYGPLVLDLRLRFRAHALMLWLEQQKLPGIIELTPGIRSLQIHFNPQVLTRQQLLKDLAGAEHALQQQD
DLEVPSRIVHIPLSWDDQACHQAIEKYIQSVRKDAPWCPSNLEFIRRINGLDSIDAVKNILFSASYVVMGLGDVYLGAPV
ATPYDPRHRLVTTKYNPARTWTAENSVGIGGAYLCVYGMEGPGGYQFVGRTLQMWNRYRKTRVFNQPWLLRFFDQIRFYE
VSHEELNQIRRDFPKGDYPLKVEETTFSLSAYQQFLDDNQQDIATFTDVRNQAFDEELQRWVDSGQINFQSEQNLEADNG
AEEVDGTPVESPVAGNIWKLNVSEGDHVQKGDVVAVLESMKMEIEIYAPGSGNVITVSRQEGQQINAGQAIMVLD

Specific function: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA [H]

COG id: COG0439

COG function: function code I; Biotin carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotin carboxylation domain [H]

Homologues:

Organism=Homo sapiens, GI116805327, Length=444, Percent_Identity=44.8198198198198, Blast_Score=387, Evalue=1e-107,
Organism=Homo sapiens, GI65506442, Length=447, Percent_Identity=42.0581655480984, Blast_Score=348, Evalue=3e-95,
Organism=Homo sapiens, GI295821183, Length=447, Percent_Identity=42.0581655480984, Blast_Score=347, Evalue=3e-95,
Organism=Homo sapiens, GI189095269, Length=447, Percent_Identity=42.0581655480984, Blast_Score=347, Evalue=3e-95,
Organism=Homo sapiens, GI106049528, Length=519, Percent_Identity=37.5722543352601, Blast_Score=312, Evalue=1e-84,
Organism=Homo sapiens, GI106049295, Length=519, Percent_Identity=37.5722543352601, Blast_Score=312, Evalue=1e-84,
Organism=Homo sapiens, GI106049292, Length=519, Percent_Identity=37.5722543352601, Blast_Score=312, Evalue=1e-84,
Organism=Homo sapiens, GI38679960, Length=509, Percent_Identity=27.8978388998035, Blast_Score=197, Evalue=4e-50,
Organism=Homo sapiens, GI38679977, Length=509, Percent_Identity=27.8978388998035, Blast_Score=197, Evalue=4e-50,
Organism=Homo sapiens, GI38679967, Length=509, Percent_Identity=27.8978388998035, Blast_Score=197, Evalue=4e-50,
Organism=Homo sapiens, GI38679971, Length=509, Percent_Identity=27.8978388998035, Blast_Score=197, Evalue=5e-50,
Organism=Homo sapiens, GI38679974, Length=509, Percent_Identity=27.8978388998035, Blast_Score=197, Evalue=5e-50,
Organism=Homo sapiens, GI134142062, Length=506, Percent_Identity=28.6561264822134, Blast_Score=192, Evalue=2e-48,
Organism=Escherichia coli, GI1789654, Length=446, Percent_Identity=40.3587443946188, Blast_Score=310, Evalue=3e-85,
Organism=Escherichia coli, GI1786930, Length=315, Percent_Identity=32.3809523809524, Blast_Score=110, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI71987519, Length=454, Percent_Identity=45.1541850220264, Blast_Score=363, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17567343, Length=447, Percent_Identity=41.3870246085011, Blast_Score=339, Evalue=4e-93,
Organism=Caenorhabditis elegans, GI17562816, Length=461, Percent_Identity=40.7809110629067, Blast_Score=329, Evalue=7e-90,
Organism=Caenorhabditis elegans, GI133931226, Length=488, Percent_Identity=28.8934426229508, Blast_Score=200, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI71997163, Length=448, Percent_Identity=28.5714285714286, Blast_Score=177, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI71997168, Length=448, Percent_Identity=28.5714285714286, Blast_Score=177, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6319685, Length=1208, Percent_Identity=43.2119205298013, Blast_Score=1071, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319695, Length=454, Percent_Identity=39.4273127753304, Blast_Score=304, Evalue=4e-83,
Organism=Saccharomyces cerevisiae, GI6321376, Length=453, Percent_Identity=39.7350993377483, Blast_Score=297, Evalue=7e-81,
Organism=Saccharomyces cerevisiae, GI6324343, Length=526, Percent_Identity=27.9467680608365, Blast_Score=202, Evalue=3e-52,
Organism=Saccharomyces cerevisiae, GI6323863, Length=501, Percent_Identity=28.5429141716567, Blast_Score=193, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24651757, Length=447, Percent_Identity=41.6107382550336, Blast_Score=363, Evalue=1e-100,
Organism=Drosophila melanogaster, GI281363050, Length=456, Percent_Identity=42.9824561403509, Blast_Score=342, Evalue=8e-94,
Organism=Drosophila melanogaster, GI24652224, Length=456, Percent_Identity=42.9824561403509, Blast_Score=342, Evalue=8e-94,
Organism=Drosophila melanogaster, GI24652222, Length=456, Percent_Identity=42.9824561403509, Blast_Score=342, Evalue=8e-94,
Organism=Drosophila melanogaster, GI24652220, Length=456, Percent_Identity=42.9824561403509, Blast_Score=342, Evalue=8e-94,
Organism=Drosophila melanogaster, GI24652218, Length=456, Percent_Identity=42.9824561403509, Blast_Score=342, Evalue=8e-94,
Organism=Drosophila melanogaster, GI24652212, Length=456, Percent_Identity=42.9824561403509, Blast_Score=342, Evalue=8e-94,
Organism=Drosophila melanogaster, GI24652210, Length=456, Percent_Identity=42.9824561403509, Blast_Score=342, Evalue=8e-94,
Organism=Drosophila melanogaster, GI24652214, Length=456, Percent_Identity=42.9824561403509, Blast_Score=342, Evalue=8e-94,
Organism=Drosophila melanogaster, GI19921944, Length=456, Percent_Identity=42.9824561403509, Blast_Score=342, Evalue=8e-94,
Organism=Drosophila melanogaster, GI24652216, Length=456, Percent_Identity=42.9824561403509, Blast_Score=342, Evalue=8e-94,
Organism=Drosophila melanogaster, GI24651759, Length=409, Percent_Identity=40.8312958435208, Blast_Score=323, Evalue=4e-88,
Organism=Drosophila melanogaster, GI161076409, Length=521, Percent_Identity=28.0230326295585, Blast_Score=185, Evalue=1e-46,
Organism=Drosophila melanogaster, GI161076407, Length=521, Percent_Identity=28.0230326295585, Blast_Score=185, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24586460, Length=521, Percent_Identity=28.0230326295585, Blast_Score=185, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24586458, Length=521, Percent_Identity=28.0230326295585, Blast_Score=185, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR011054 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2 [H]

EC number: =6.3.4.14; =6.4.1.2 [H]

Molecular weight: Translated: 131728; Mature: 131728

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS50975 ATP_GRASP ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50968 BIOTINYL_LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNKVLIANRGAIATRVTRTLQSLGITSIAVFAEADRDSLHVRYADKAFCLGEGNAQDTY
CCCEEEEECCCCHHHHHHHHHHHCCCEEEEEEEECCCCCEEEEECCCEEEECCCCCCCCE
LNQDKLFALMEEHGVEAVHPGYGFLSENPDFVKGCEARGIAFIGPTPEQMDTFGLKHTAR
ECHHHHHHHHHHCCCCEECCCCCCCCCCCHHHHCCCCCCEEEECCCHHHHHHHCHHHHHH
ALAEKNDVPLLPGTGLLNDKEAALKAAEKIRYPVMLKSTAGGGGIGMQICDNAENLDKAW
HHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCEEEECCHHHHHHHH
DSVRRLSANNFSNDGVFIEKYIARARHIEVQVFGDGKGQAVTLGERDCSAQRRHQKVLEE
HHHHHHHCCCCCCCCCHHHHHHHHHEEEEEEEEECCCCCEEEECCCCCHHHHHHHHHHHH
TPAPNLPDHVRHELHDTARTLMQAVHYRNAGTVEFILDQDTNTFYFLEVNTRLQVEHGVT
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEECCEEEECCCCH
EQIFGVDLVEWMIKLAAGELPALNSLGPFTPNGHAIQARIYAEDPAKDFQPSAGLLTAVT
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCEEEEEE
FPEADGQALRIDHWVEAGLTVSPLFDPMLAKVIIHQADRDSALNALAQTLDGITLEGIET
CCCCCCCEEEEEHHHHCCCEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEECCCC
NREYVRTILANPVFAQGRMTTRYLNDFRYRPFTVDVLAGGTMTTVQDYPGRSGYWPVGVP
CHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCEEEEEECCCCCCCCCCCCCC
PSGPFDNLSFRLGNRLLGNDEAAAGLEFTLNGPTLKFNQATRIALTGADMQASLDSRPVP
CCCCCCCCHHHHCCCCCCCCCCCCCEEEEECCCEEEECCCEEEEEECCCCCCCCCCCCCC
PYQVIQVQPGQVLKLGKVSGEGARAYLAIASGIQCTPYLGSRSTFTLGQFGGHGGRALRT
CEEEEEECCCCEEEEECCCCCCCEEEEEEECCCEECCCCCCCCEEEEECCCCCCCCEEEC
GDVLHFSEDTGITARVEVPASLKPELGKAWTLRVIYGPHGAPDFFTDDDMAMFFSTDWQV
CCEEEEECCCCEEEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEECCEEE
HYNSSRTGIRLVGPKPNWARSDGGEAGMHPSNIHDNAYAVGTVDFTGDMPVILGPDGPSL
EECCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEEECCCCCCC
GGFVCPATVVLADRWKLGQLKAGDTLRFEAISLDDADTLAAEQDHCVSSLVEPAKRVKSA
CCCCCCEEEEEECCCCCCCCCCCCEEEEEEEECCCCHHHHCCHHHHHHHHHHHHHHHHHH
VITTPVLNTLSKQEAGVDVVYRAAGDRYLLVEYGPLVLDLRLRFRAHALMLWLEQQKLPG
HHHHHHHHHHHHHCCCCEEEEEECCCEEEEEECCCEEEEEHHHHHHHHHHEEEHHCCCCC
IIELTPGIRSLQIHFNPQVLTRQQLLKDLAGAEHALQQQDDLEVPSRIVHIPLSWDDQAC
EEEECCCCEEEEEEECCHHHHHHHHHHHHHCHHHHHCCCCCCCCCCEEEEEECCCCHHHH
HQAIEKYIQSVRKDAPWCPSNLEFIRRINGLDSIDAVKNILFSASYVVMGLGDVYLGAPV
HHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCEEEEECCCHHCCCCC
ATPYDPRHRLVTTKYNPARTWTAENSVGIGGAYLCVYGMEGPGGYQFVGRTLQMWNRYRK
CCCCCCCCCEEEEECCCCEEEECCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHH
TRVFNQPWLLRFFDQIRFYEVSHEELNQIRRDFPKGDYPLKVEETTFSLSAYQQFLDDNQ
HHCCCCCHHHHHHHHHHEEECCHHHHHHHHHHCCCCCCCEEEECCEEEHHHHHHHHCCCH
QDIATFTDVRNQAFDEELQRWVDSGQINFQSEQNLEADNGAEEVDGTPVESPVAGNIWKL
HHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCHHCCCCCCCCCCCCCEEEE
NVSEGDHVQKGDVVAVLESMKMEIEIYAPGSGNVITVSRQEGQQINAGQAIMVLD
ECCCCCCCCCCCHHHEECCCCEEEEEEECCCCCEEEEECCCCCCCCCCCEEEEEC
>Mature Secondary Structure
MFNKVLIANRGAIATRVTRTLQSLGITSIAVFAEADRDSLHVRYADKAFCLGEGNAQDTY
CCCEEEEECCCCHHHHHHHHHHHCCCEEEEEEEECCCCCEEEEECCCEEEECCCCCCCCE
LNQDKLFALMEEHGVEAVHPGYGFLSENPDFVKGCEARGIAFIGPTPEQMDTFGLKHTAR
ECHHHHHHHHHHCCCCEECCCCCCCCCCCHHHHCCCCCCEEEECCCHHHHHHHCHHHHHH
ALAEKNDVPLLPGTGLLNDKEAALKAAEKIRYPVMLKSTAGGGGIGMQICDNAENLDKAW
HHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCEEEECCHHHHHHHH
DSVRRLSANNFSNDGVFIEKYIARARHIEVQVFGDGKGQAVTLGERDCSAQRRHQKVLEE
HHHHHHHCCCCCCCCCHHHHHHHHHEEEEEEEEECCCCCEEEECCCCCHHHHHHHHHHHH
TPAPNLPDHVRHELHDTARTLMQAVHYRNAGTVEFILDQDTNTFYFLEVNTRLQVEHGVT
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEECCEEEECCCCH
EQIFGVDLVEWMIKLAAGELPALNSLGPFTPNGHAIQARIYAEDPAKDFQPSAGLLTAVT
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCEEEEEE
FPEADGQALRIDHWVEAGLTVSPLFDPMLAKVIIHQADRDSALNALAQTLDGITLEGIET
CCCCCCCEEEEEHHHHCCCEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEECCCC
NREYVRTILANPVFAQGRMTTRYLNDFRYRPFTVDVLAGGTMTTVQDYPGRSGYWPVGVP
CHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCEEEEEECCCCCCCCCCCCCC
PSGPFDNLSFRLGNRLLGNDEAAAGLEFTLNGPTLKFNQATRIALTGADMQASLDSRPVP
CCCCCCCCHHHHCCCCCCCCCCCCCEEEEECCCEEEECCCEEEEEECCCCCCCCCCCCCC
PYQVIQVQPGQVLKLGKVSGEGARAYLAIASGIQCTPYLGSRSTFTLGQFGGHGGRALRT
CEEEEEECCCCEEEEECCCCCCCEEEEEEECCCEECCCCCCCCEEEEECCCCCCCCEEEC
GDVLHFSEDTGITARVEVPASLKPELGKAWTLRVIYGPHGAPDFFTDDDMAMFFSTDWQV
CCEEEEECCCCEEEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEECCEEE
HYNSSRTGIRLVGPKPNWARSDGGEAGMHPSNIHDNAYAVGTVDFTGDMPVILGPDGPSL
EECCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEEECCCCCCC
GGFVCPATVVLADRWKLGQLKAGDTLRFEAISLDDADTLAAEQDHCVSSLVEPAKRVKSA
CCCCCCEEEEEECCCCCCCCCCCCEEEEEEEECCCCHHHHCCHHHHHHHHHHHHHHHHHH
VITTPVLNTLSKQEAGVDVVYRAAGDRYLLVEYGPLVLDLRLRFRAHALMLWLEQQKLPG
HHHHHHHHHHHHHCCCCEEEEEECCCEEEEEECCCEEEEEHHHHHHHHHHEEEHHCCCCC
IIELTPGIRSLQIHFNPQVLTRQQLLKDLAGAEHALQQQDDLEVPSRIVHIPLSWDDQAC
EEEECCCCEEEEEEECCHHHHHHHHHHHHHCHHHHHCCCCCCCCCCEEEEEECCCCHHHH
HQAIEKYIQSVRKDAPWCPSNLEFIRRINGLDSIDAVKNILFSASYVVMGLGDVYLGAPV
HHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCEEEEECCCHHCCCCC
ATPYDPRHRLVTTKYNPARTWTAENSVGIGGAYLCVYGMEGPGGYQFVGRTLQMWNRYRK
CCCCCCCCCEEEEECCCCEEEECCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHH
TRVFNQPWLLRFFDQIRFYEVSHEELNQIRRDFPKGDYPLKVEETTFSLSAYQQFLDDNQ
HHCCCCCHHHHHHHHHHEEECCHHHHHHHHHHCCCCCCCEEEECCEEEHHHHHHHHCCCH
QDIATFTDVRNQAFDEELQRWVDSGQINFQSEQNLEADNGAEEVDGTPVESPVAGNIWKL
HHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCHHCCCCCCCCCCCCCEEEE
NVSEGDHVQKGDVVAVLESMKMEIEIYAPGSGNVITVSRQEGQQINAGQAIMVLD
ECCCCCCCCCCCHHHEECCCCEEEEEEECCCCCEEEEECCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]