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The map label for this gene is aapB [H]

Identifier: 110834727

GI number: 110834727

Start: 2142311

End: 2143066

Strand: Direct

Name: aapB [H]

Synonym: ABO_1866

Alternate gene names: 110834727

Gene position: 2142311-2143066 (Clockwise)

Preceding gene: 110834726

Following gene: 110834728

Centisome position: 68.66

GC content: 57.8

Gene sequence:

>756_bases
ATGCTGGAAATTCGTGATCTGCACGCCACCGTGGCGGACAAGCCGATTCTCAAGGGCCTGAACCTGACCGTTAAACCGGG
TGAAGTGCACGCCATCATGGGCCCCAATGGCTCCGGCAAATCCACTCTGGCCAACGTGCTGGCGGGTCGTGACAATTACG
CAATCACCGGTGGTGAAGCCCTTTTCGAAGGCAAAAGCCTGGCAGACCTAGAACCGGAAGAACGCGCCCAGGCTGGCCTG
TTCCTGGCCTTCCAGTACCCGGTGGAAATTCCCGGCGTCTCCAACATGGAATTTCTGAAAGCCGCACTGGAATCTGTGCG
CGGCGCCCAAGGTAAGGAAGAGTGGGATTCGGTTACGCTACTGCGCCAGGCCCGCGCAGCCTGCAAGCAAGTCAATCTCG
ATGCCAGCTTCCTCAAGCGCGGGGTTAACGAAGGCTTCTCTGGCGGCGAGAAAAAGCGCAACGAAATCATGCAAATGCTG
CTGATGGAACCGAAACTGGCGCTGCTCGATGAAACCGACTCCGGCCTCGACATCGACGCCCTGCAAACCGTGGCCAAGGG
CGTCAATTCCCTGCGCAGCCCCGAGCGCGGCATCGTGCTGGTAACCCACTATCAACGCCTGCTGGACTATATTGTGCCGG
ACTTCGTGCACGTCCTGTCCAATGGCCAAATCATCAAATCCGGGGGTAAAGAACTGGCTCTCGAACTGGAAGAAAAAGGT
TACGGCTGGCTTACCGGAGAAGAGGAATCCGCATGA

Upstream 100 bases:

>100_bases
TCACCCTTTACCAATCATGGATCGCGAGCAGGCCGGCGCCCACCGCAAACCGAATCAACCCGGGCTGGCCTCCCAGCCCA
ACCGAAAGGCGCATCAAAAT

Downstream 100 bases:

>100_bases
GTCTCTCTGCTTCCTCTCTAGCACAGGAATTAAAAACCCAAGCGCTCGCCAACGCACAGCGTAACGGCAGCGCAGGCGAT
GCTTTGGCCGCGCTGCAAGC

Product: ATP-binding protein of ABC-transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MLEIRDLHATVADKPILKGLNLTVKPGEVHAIMGPNGSGKSTLANVLAGRDNYAITGGEALFEGKSLADLEPEERAQAGL
FLAFQYPVEIPGVSNMEFLKAALESVRGAQGKEEWDSVTLLRQARAACKQVNLDASFLKRGVNEGFSGGEKKRNEIMQML
LMEPKLALLDETDSGLDIDALQTVAKGVNSLRSPERGIVLVTHYQRLLDYIVPDFVHVLSNGQIIKSGGKELALELEEKG
YGWLTGEEESA

Sequences:

>Translated_251_residues
MLEIRDLHATVADKPILKGLNLTVKPGEVHAIMGPNGSGKSTLANVLAGRDNYAITGGEALFEGKSLADLEPEERAQAGL
FLAFQYPVEIPGVSNMEFLKAALESVRGAQGKEEWDSVTLLRQARAACKQVNLDASFLKRGVNEGFSGGEKKRNEIMQML
LMEPKLALLDETDSGLDIDALQTVAKGVNSLRSPERGIVLVTHYQRLLDYIVPDFVHVLSNGQIIKSGGKELALELEEKG
YGWLTGEEESA
>Mature_251_residues
MLEIRDLHATVADKPILKGLNLTVKPGEVHAIMGPNGSGKSTLANVLAGRDNYAITGGEALFEGKSLADLEPEERAQAGL
FLAFQYPVEIPGVSNMEFLKAALESVRGAQGKEEWDSVTLLRQARAACKQVNLDASFLKRGVNEGFSGGEKKRNEIMQML
LMEPKLALLDETDSGLDIDALQTVAKGVNSLRSPERGIVLVTHYQRLLDYIVPDFVHVLSNGQIIKSGGKELALELEEKG
YGWLTGEEESA

Specific function: Has low ATPase activity. The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May f

COG id: COG0396

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, ATPase component

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI73747915, Length=196, Percent_Identity=31.6326530612245, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI73747917, Length=175, Percent_Identity=33.1428571428571, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI46592898, Length=240, Percent_Identity=28.75, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI46592978, Length=240, Percent_Identity=28.75, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI46592915, Length=240, Percent_Identity=28.75, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI46592964, Length=240, Percent_Identity=28.75, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI46592956, Length=240, Percent_Identity=28.75, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI46592971, Length=240, Percent_Identity=28.75, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI62526033, Length=236, Percent_Identity=27.9661016949153, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI42741659, Length=230, Percent_Identity=26.9565217391304, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI11967969, Length=236, Percent_Identity=27.9661016949153, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787972, Length=248, Percent_Identity=58.8709677419355, Blast_Score=303, Evalue=5e-84,
Organism=Escherichia coli, GI1788225, Length=238, Percent_Identity=30.2521008403361, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1790190, Length=225, Percent_Identity=28.4444444444444, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787029, Length=206, Percent_Identity=30.0970873786408, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1789891, Length=222, Percent_Identity=30.6306306306306, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1789672, Length=218, Percent_Identity=27.9816513761468, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790525, Length=212, Percent_Identity=28.3018867924528, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1789864, Length=230, Percent_Identity=25.6521739130435, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787792, Length=231, Percent_Identity=26.8398268398268, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1786319, Length=188, Percent_Identity=29.2553191489362, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790467, Length=212, Percent_Identity=28.7735849056604, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1787712, Length=226, Percent_Identity=28.3185840707965, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87082267, Length=162, Percent_Identity=30.8641975308642, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87081709, Length=231, Percent_Identity=23.3766233766234, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1789593, Length=230, Percent_Identity=25.6521739130435, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1787500, Length=218, Percent_Identity=28.4403669724771, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1786654, Length=246, Percent_Identity=27.6422764227642, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI87081834, Length=192, Percent_Identity=29.1666666666667, Blast_Score=61, Evalue=7e-11,
Organism=Escherichia coli, GI87081782, Length=230, Percent_Identity=25.2173913043478, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71992290, Length=242, Percent_Identity=30.5785123966942, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17541710, Length=237, Percent_Identity=32.0675105485232, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI71996809, Length=225, Percent_Identity=30.2222222222222, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193211017, Length=225, Percent_Identity=29.7777777777778, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI193211015, Length=225, Percent_Identity=29.7777777777778, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI212646699, Length=226, Percent_Identity=29.646017699115, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17558664, Length=223, Percent_Identity=28.2511210762332, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17511077, Length=236, Percent_Identity=26.6949152542373, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17539902, Length=218, Percent_Identity=27.5229357798165, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6324498, Length=204, Percent_Identity=30.3921568627451, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319856, Length=239, Percent_Identity=28.4518828451883, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641565, Length=222, Percent_Identity=29.2792792792793, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI85726357, Length=251, Percent_Identity=26.6932270916335, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI161076682, Length=252, Percent_Identity=28.968253968254, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI161076684, Length=252, Percent_Identity=28.968253968254, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24581617, Length=252, Percent_Identity=28.968253968254, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24581615, Length=252, Percent_Identity=28.968253968254, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24666092, Length=226, Percent_Identity=28.3185840707965, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010230 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 27246; Mature: 27246

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEIRDLHATVADKPILKGLNLTVKPGEVHAIMGPNGSGKSTLANVLAGRDNYAITGGEA
CCCCHHHHHHHHCCHHHCCCCEEECCCCEEEEECCCCCCHHHHHHHHHCCCCEEEECCHH
LFEGKSLADLEPEERAQAGLFLAFQYPVEIPGVSNMEFLKAALESVRGAQGKEEWDSVTL
HCCCCCCCCCCHHHHHCCCEEEEEECCEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHH
LRQARAACKQVNLDASFLKRGVNEGFSGGEKKRNEIMQMLLMEPKLALLDETDSGLDIDA
HHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCHHH
LQTVAKGVNSLRSPERGIVLVTHYQRLLDYIVPDFVHVLSNGQIIKSGGKELALELEEKG
HHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEEECCCC
YGWLTGEEESA
CEEECCCCCCC
>Mature Secondary Structure
MLEIRDLHATVADKPILKGLNLTVKPGEVHAIMGPNGSGKSTLANVLAGRDNYAITGGEA
CCCCHHHHHHHHCCHHHCCCCEEECCCCEEEEECCCCCCHHHHHHHHHCCCCEEEECCHH
LFEGKSLADLEPEERAQAGLFLAFQYPVEIPGVSNMEFLKAALESVRGAQGKEEWDSVTL
HCCCCCCCCCCHHHHHCCCEEEEEECCEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHH
LRQARAACKQVNLDASFLKRGVNEGFSGGEKKRNEIMQMLLMEPKLALLDETDSGLDIDA
HHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCHHH
LQTVAKGVNSLRSPERGIVLVTHYQRLLDYIVPDFVHVLSNGQIIKSGGKELALELEEKG
HHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEEECCCC
YGWLTGEEESA
CEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]