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The map label for this gene is xseA

Identifier: 110834713

GI number: 110834713

Start: 2124842

End: 2126188

Strand: Direct

Name: xseA

Synonym: ABO_1852

Alternate gene names: 110834713

Gene position: 2124842-2126188 (Clockwise)

Preceding gene: 110834705

Following gene: 110834726

Centisome position: 68.1

GC content: 60.73

Gene sequence:

>1347_bases
ATGACCATTTCATCCCGCGCCGAACCGCTGTCTATCAGCCAGTTAAACCTGGATGCCCAGGGCCTGCTGGAAAGTTCTTT
TCCCCTGATTTGGCTCCAGGGAGAGCTGTCCAACTTCTCTCGCCCGGCCTCCGGCCACTGGTATTTCAGCCTGAAAGACA
CCCGTGCCCAGATTAATGGAGCCATGTTTCGTAATCGTAACAGGCTACTGAATTTTGCCCCCCAAAACGGGGAACAGGTG
CTGGTGCGCGCCAAGATCACCCTTTACGTTCCCCGCGGCAATTTCCAGATTGTGGTCGAACACATGGAGCCCGCTGGCCA
GGGCGCATTAAAAGCCCAGTTCGACGCCTTGAAAGCCCAGCTACAAAGTGAAGGCCTGTTCGCCCAGGAACACAAACGAA
CGCTGCCCGCCTGGCCCAACCAGATTGGGGTCATCACCTCACCCAGCGGCGCCGCTATTCGCGATATTTTGCAAGTACTG
CAGCGCCGATGCCCTTCCATACCCGTGCTGATCTACCCCGCTGCCGTTCAAGGAGCCGAGGCTCCGGCGCAATTGCGCCA
AGCGCTGGCATTGGCCGTGGCACGTAATGAATGTGATGTGCTGATCCTGGGGCGTGGCGGCGGTTCTCTGGAGGACTTGT
GGGCATTCAATGACGAAGGGTTGGCCCGAGCCGTGGCGAACTGCCCCATTCCCATTGTTTCAGCGGTGGGCCATGAAGTG
GACACCGGCTTGACCGACTTTGCCGCCGACCTACGCGCGCCTACCCCCTCCGCCGCCGCCGAGCTGGTGAGCCCGGATCT
CTCCATTGTCAGTCAACGACTTGCGGGGCTACACCGGCGACTTCGCTGGGTCATGGCGCAAGAGCTACGTACTGTGCAAG
AGCGCCTGCGCCATCTCAGCCAACGGCTGCGCTCCCCCCGCCAGCACCTTGAACAGAGCAGCCAGCGACTGGATGAGCTA
CAAAACCGCCTGCAGCGGCAAATGCAACATCGCCTCACCCTGCTGCAGGGCCGCCTGCAACCCAGCCAGCAACGGCTGGC
GCGGCTGTCCCCGCAACGATTGCTGGTGGAGCGCCAGCAACGGCTAGCAACCCTGAGCAAGCGACTCCCTCAGCCAATCC
TGCGCCAACTTCAGCAGCAACAACTGCAGCTAGCCGGGTTGAGTAAGCGCCTGCATACCGCCAGCCCGCTGGAAACCCTA
GCACGGGGATACAGTATTACTTTTAAGGGGAACCAGGCGGTGCGCTCTGTGGAACAGCTGCAAGCCGGCGACACCCTGAC
TACCCGGCTGGCCGACGGCGAAATTATCGCCCGGGTAGAACACGTCCAGGTGTCAGATACGGACTGA

Upstream 100 bases:

>100_bases
ACAGGCACCCCGTTAAATTAGGCGGGCGATTATACGACATTACCGGCTAACCACACAATCACCGCTGGCAGGGTACAAAA
AAACGGGCTACCCTCCCGCG

Downstream 100 bases:

>100_bases
GCACTCGCGCCAATTGCTGGCGCCGGAAGGGTTTGGCGAGATGGGAGTTCATCCCCGCCGCTAGGCAACGTTCACGTTCT
TCATTCATGGCATTGGCGGT

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit

Number of amino acids: Translated: 448; Mature: 447

Protein sequence:

>448_residues
MTISSRAEPLSISQLNLDAQGLLESSFPLIWLQGELSNFSRPASGHWYFSLKDTRAQINGAMFRNRNRLLNFAPQNGEQV
LVRAKITLYVPRGNFQIVVEHMEPAGQGALKAQFDALKAQLQSEGLFAQEHKRTLPAWPNQIGVITSPSGAAIRDILQVL
QRRCPSIPVLIYPAAVQGAEAPAQLRQALALAVARNECDVLILGRGGGSLEDLWAFNDEGLARAVANCPIPIVSAVGHEV
DTGLTDFAADLRAPTPSAAAELVSPDLSIVSQRLAGLHRRLRWVMAQELRTVQERLRHLSQRLRSPRQHLEQSSQRLDEL
QNRLQRQMQHRLTLLQGRLQPSQQRLARLSPQRLLVERQQRLATLSKRLPQPILRQLQQQQLQLAGLSKRLHTASPLETL
ARGYSITFKGNQAVRSVEQLQAGDTLTTRLADGEIIARVEHVQVSDTD

Sequences:

>Translated_448_residues
MTISSRAEPLSISQLNLDAQGLLESSFPLIWLQGELSNFSRPASGHWYFSLKDTRAQINGAMFRNRNRLLNFAPQNGEQV
LVRAKITLYVPRGNFQIVVEHMEPAGQGALKAQFDALKAQLQSEGLFAQEHKRTLPAWPNQIGVITSPSGAAIRDILQVL
QRRCPSIPVLIYPAAVQGAEAPAQLRQALALAVARNECDVLILGRGGGSLEDLWAFNDEGLARAVANCPIPIVSAVGHEV
DTGLTDFAADLRAPTPSAAAELVSPDLSIVSQRLAGLHRRLRWVMAQELRTVQERLRHLSQRLRSPRQHLEQSSQRLDEL
QNRLQRQMQHRLTLLQGRLQPSQQRLARLSPQRLLVERQQRLATLSKRLPQPILRQLQQQQLQLAGLSKRLHTASPLETL
ARGYSITFKGNQAVRSVEQLQAGDTLTTRLADGEIIARVEHVQVSDTD
>Mature_447_residues
TISSRAEPLSISQLNLDAQGLLESSFPLIWLQGELSNFSRPASGHWYFSLKDTRAQINGAMFRNRNRLLNFAPQNGEQVL
VRAKITLYVPRGNFQIVVEHMEPAGQGALKAQFDALKAQLQSEGLFAQEHKRTLPAWPNQIGVITSPSGAAIRDILQVLQ
RRCPSIPVLIYPAAVQGAEAPAQLRQALALAVARNECDVLILGRGGGSLEDLWAFNDEGLARAVANCPIPIVSAVGHEVD
TGLTDFAADLRAPTPSAAAELVSPDLSIVSQRLAGLHRRLRWVMAQELRTVQERLRHLSQRLRSPRQHLEQSSQRLDELQ
NRLQRQMQHRLTLLQGRLQPSQQRLARLSPQRLLVERQQRLATLSKRLPQPILRQLQQQQLQLAGLSKRLHTASPLETLA
RGYSITFKGNQAVRSVEQLQAGDTLTTRLADGEIIARVEHVQVSDTD

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family

Homologues:

Organism=Escherichia coli, GI1788856, Length=438, Percent_Identity=48.6301369863014, Blast_Score=398, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EX7L_ALCBS (Q0VNE8)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_693572.1
- STRING:   Q0VNE8
- GeneID:   4211779
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_1852
- NMPDR:   fig|393595.12.peg.1857
- eggNOG:   COG1570
- HOGENOM:   HBG634411
- OMA:   SSQIRCA
- PhylomeDB:   Q0VNE8
- BioCyc:   ABOR393595:ABO_1852-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00378
- InterPro:   IPR003753
- InterPro:   IPR020579
- TIGRFAMs:   TIGR00237

Pfam domain/function: PF02601 Exonuc_VII_L

EC number: =3.1.11.6

Molecular weight: Translated: 49858; Mature: 49727

Theoretical pI: Translated: 10.90; Mature: 10.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISSRAEPLSISQLNLDAQGLLESSFPLIWLQGELSNFSRPASGHWYFSLKDTRAQING
CCCCCCCCCCEEEEECCCHHHHHHCCCCEEEEECCCCCCCCCCCCCEEEEEEHHHHHHHH
AMFRNRNRLLNFAPQNGEQVLVRAKITLYVPRGNFQIVVEHMEPAGQGALKAQFDALKAQ
HHHHCCCHHEEECCCCCCEEEEEEEEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHH
LQSEGLFAQEHKRTLPAWPNQIGVITSPSGAAIRDILQVLQRRCPSIPVLIYPAAVQGAE
HHHCCCCHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCC
APAQLRQALALAVARNECDVLILGRGGGSLEDLWAFNDEGLARAVANCPIPIVSAVGHEV
CHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHCCCCCHHHHHHHCCCCHHHHHCCCHH
DTGLTDFAADLRAPTPSAAAELVSPDLSIVSQRLAGLHRRLRWVMAQELRTVQERLRHLS
HCCHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRLRSPRQHLEQSSQRLDELQNRLQRQMQHRLTLLQGRLQPSQQRLARLSPQRLLVERQQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHH
RLATLSKRLPQPILRQLQQQQLQLAGLSKRLHTASPLETLARGYSITFKGNQAVRSVEQL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEECCCHHHHHHHHH
QAGDTLTTRLADGEIIARVEHVQVSDTD
HCCCCCEEEECCCCEEEEEEEEEECCCC
>Mature Secondary Structure 
TISSRAEPLSISQLNLDAQGLLESSFPLIWLQGELSNFSRPASGHWYFSLKDTRAQING
CCCCCCCCCEEEEECCCHHHHHHCCCCEEEEECCCCCCCCCCCCCEEEEEEHHHHHHHH
AMFRNRNRLLNFAPQNGEQVLVRAKITLYVPRGNFQIVVEHMEPAGQGALKAQFDALKAQ
HHHHCCCHHEEECCCCCCEEEEEEEEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHH
LQSEGLFAQEHKRTLPAWPNQIGVITSPSGAAIRDILQVLQRRCPSIPVLIYPAAVQGAE
HHHCCCCHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCC
APAQLRQALALAVARNECDVLILGRGGGSLEDLWAFNDEGLARAVANCPIPIVSAVGHEV
CHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHCCCCCHHHHHHHCCCCHHHHHCCCHH
DTGLTDFAADLRAPTPSAAAELVSPDLSIVSQRLAGLHRRLRWVMAQELRTVQERLRHLS
HCCHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRLRSPRQHLEQSSQRLDELQNRLQRQMQHRLTLLQGRLQPSQQRLARLSPQRLLVERQQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHH
RLATLSKRLPQPILRQLQQQQLQLAGLSKRLHTASPLETLARGYSITFKGNQAVRSVEQL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEECCCHHHHHHHHH
QAGDTLTTRLADGEIIARVEHVQVSDTD
HCCCCCEEEECCCCEEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA