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The map label for this gene is gpm [H]

Identifier: 110834630

GI number: 110834630

Start: 2016170

End: 2016916

Strand: Direct

Name: gpm [H]

Synonym: ABO_1769

Alternate gene names: 110834630

Gene position: 2016170-2016916 (Clockwise)

Preceding gene: 110834624

Following gene: 110834631

Centisome position: 64.62

GC content: 50.87

Gene sequence:

>747_bases
ATGAGCACGAAACTGGTACTGGTCCGCCACGGCCAGAGCGTATGGAACAAGGAAAATCGCTTCACAGGCTGGAAAGATGT
TGATCTTACCGAGCAAGGCCGCGAAGAAGCCCGCACCGCAGGCGAACTACTGAAAGAGGCCGGGTTTGAATTTGACCTGG
CTTATACCTCGGTGCTCAAGCGTGCGATCCGCACCCTGTGGAGCATTCTGGATAACATGGACCAGATGTGGATCCCTGTT
ATCCGTGACTACCGCTTGAATGAACGCCACTACGGTGCCTTGCAGGGTTTGAATAAAGCGGAAACAGCCGCCAAATATGG
CGACGACCAGGTACATATATGGCGCCGTAGCTACGATACGCCGCCACCGAAAATGGAACGTGACGATGAGCGCTACGCTG
GCAACTTCCGAGTGTACAAGGACTTGAGTGAAGCTCAAATTCCTTTGTCAGAAAGTCTTAAAGACACGGTGGACCGTTTT
ATTCCTTACTTCGAAAGTGATATCAAACCGCAAATTCAAGCTGGGAAACAGGTTTTAATCTGCGCCCATGGCAATAGTCT
GCGTGCGCTGGTGAAGTATCTCGGCGACATTTCTGACGAAGAAATCGTAAAGCTCAACATCCCTACTGGAGTGCCGATGG
TTTATGAGCTGGACGACAATCTCAAACCCATTAAAAACTACTATTTGGGCGATGCCGAAGCTGCAGCGAAAGCGGCAGAA
GCAGTCGCCAACCAAGGTAAGGCGTAA

Upstream 100 bases:

>100_bases
ACAACAGAATTTGCGACGATTATACGGCCTGTGGCGCTCAATTTCCCGGCACATTTCTGCTACTCTTTGCGCCGCATTGA
AATCGCACAGGATGACGCTA

Downstream 100 bases:

>100_bases
GCAGGCAAGCTAGGAACCTGCCACAAAAAAGCCCCGCCAAACCCGGCGGGGCTTTTTTGTGCTTCATACCTTCGTCATCA
TACAAGCATAGCTTCTCACA

Product: phosphoglycerate mutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MSTKLVLVRHGQSVWNKENRFTGWKDVDLTEQGREEARTAGELLKEAGFEFDLAYTSVLKRAIRTLWSILDNMDQMWIPV
IRDYRLNERHYGALQGLNKAETAAKYGDDQVHIWRRSYDTPPPKMERDDERYAGNFRVYKDLSEAQIPLSESLKDTVDRF
IPYFESDIKPQIQAGKQVLICAHGNSLRALVKYLGDISDEEIVKLNIPTGVPMVYELDDNLKPIKNYYLGDAEAAAKAAE
AVANQGKA

Sequences:

>Translated_248_residues
MSTKLVLVRHGQSVWNKENRFTGWKDVDLTEQGREEARTAGELLKEAGFEFDLAYTSVLKRAIRTLWSILDNMDQMWIPV
IRDYRLNERHYGALQGLNKAETAAKYGDDQVHIWRRSYDTPPPKMERDDERYAGNFRVYKDLSEAQIPLSESLKDTVDRF
IPYFESDIKPQIQAGKQVLICAHGNSLRALVKYLGDISDEEIVKLNIPTGVPMVYELDDNLKPIKNYYLGDAEAAAKAAE
AVANQGKA
>Mature_247_residues
STKLVLVRHGQSVWNKENRFTGWKDVDLTEQGREEARTAGELLKEAGFEFDLAYTSVLKRAIRTLWSILDNMDQMWIPVI
RDYRLNERHYGALQGLNKAETAAKYGDDQVHIWRRSYDTPPPKMERDDERYAGNFRVYKDLSEAQIPLSESLKDTVDRFI
PYFESDIKPQIQAGKQVLICAHGNSLRALVKYLGDISDEEIVKLNIPTGVPMVYELDDNLKPIKNYYLGDAEAAAKAAEA
VANQGKA

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=250, Percent_Identity=58.4, Blast_Score=310, Evalue=7e-85,
Organism=Homo sapiens, GI4505753, Length=248, Percent_Identity=62.0967741935484, Blast_Score=306, Evalue=8e-84,
Organism=Homo sapiens, GI71274132, Length=248, Percent_Identity=59.6774193548387, Blast_Score=293, Evalue=1e-79,
Organism=Homo sapiens, GI4502445, Length=250, Percent_Identity=50, Blast_Score=256, Evalue=2e-68,
Organism=Homo sapiens, GI40353764, Length=250, Percent_Identity=50, Blast_Score=256, Evalue=2e-68,
Organism=Homo sapiens, GI310129614, Length=161, Percent_Identity=62.7329192546584, Blast_Score=203, Evalue=1e-52,
Organism=Escherichia coli, GI1786970, Length=246, Percent_Identity=65.0406504065041, Blast_Score=335, Evalue=2e-93,
Organism=Saccharomyces cerevisiae, GI6322697, Length=244, Percent_Identity=53.6885245901639, Blast_Score=243, Evalue=2e-65,
Organism=Saccharomyces cerevisiae, GI6320183, Length=299, Percent_Identity=34.4481605351171, Blast_Score=149, Evalue=5e-37,
Organism=Saccharomyces cerevisiae, GI6324516, Length=292, Percent_Identity=32.5342465753425, Blast_Score=139, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6324857, Length=238, Percent_Identity=25.2100840336134, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24646216, Length=249, Percent_Identity=55.8232931726908, Blast_Score=278, Evalue=3e-75,
Organism=Drosophila melanogaster, GI85725270, Length=249, Percent_Identity=54.2168674698795, Blast_Score=256, Evalue=1e-68,
Organism=Drosophila melanogaster, GI85725272, Length=249, Percent_Identity=54.2168674698795, Blast_Score=256, Evalue=1e-68,
Organism=Drosophila melanogaster, GI24650981, Length=249, Percent_Identity=54.2168674698795, Blast_Score=256, Evalue=1e-68,
Organism=Drosophila melanogaster, GI28571817, Length=220, Percent_Identity=40.9090909090909, Blast_Score=178, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24648979, Length=220, Percent_Identity=40.9090909090909, Blast_Score=178, Evalue=3e-45,
Organism=Drosophila melanogaster, GI28571815, Length=220, Percent_Identity=40.9090909090909, Blast_Score=178, Evalue=3e-45,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 28300; Mature: 28169

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTKLVLVRHGQSVWNKENRFTGWKDVDLTEQGREEARTAGELLKEAGFEFDLAYTSVLK
CCCEEEEEECCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RAIRTLWSILDNMDQMWIPVIRDYRLNERHYGALQGLNKAETAAKYGDDQVHIWRRSYDT
HHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHCCCCEEEEEECCCCC
PPPKMERDDERYAGNFRVYKDLSEAQIPLSESLKDTVDRFIPYFESDIKPQIQAGKQVLI
CCCCCCCCCHHHCCCCCEECCHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEE
CAHGNSLRALVKYLGDISDEEIVKLNIPTGVPMVYELDDNLKPIKNYYLGDAEAAAKAAE
EECCCHHHHHHHHHCCCCCCCEEEEECCCCCCEEEECCCCCHHHHHHCCCCHHHHHHHHH
AVANQGKA
HHHHCCCC
>Mature Secondary Structure 
STKLVLVRHGQSVWNKENRFTGWKDVDLTEQGREEARTAGELLKEAGFEFDLAYTSVLK
CCEEEEEECCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RAIRTLWSILDNMDQMWIPVIRDYRLNERHYGALQGLNKAETAAKYGDDQVHIWRRSYDT
HHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHCCCCEEEEEECCCCC
PPPKMERDDERYAGNFRVYKDLSEAQIPLSESLKDTVDRFIPYFESDIKPQIQAGKQVLI
CCCCCCCCCHHHCCCCCEECCHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEE
CAHGNSLRALVKYLGDISDEEIVKLNIPTGVPMVYELDDNLKPIKNYYLGDAEAAAKAAE
EECCCHHHHHHHHHCCCCCCCEEEEECCCCCCEEEECCCCCHHHHHHCCCCHHHHHHHHH
AVANQGKA
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA