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The map label for this gene is moaC

Identifier: 110834138

GI number: 110834138

Start: 1451996

End: 1452478

Strand: Direct

Name: moaC

Synonym: ABO_1277

Alternate gene names: 110834138

Gene position: 1451996-1452478 (Clockwise)

Preceding gene: 110834129

Following gene: 110834139

Centisome position: 46.54

GC content: 57.56

Gene sequence:

>483_bases
ATGACTGAACAACGATTTACCCACCTGGACGACAGTGGTCGGGCCCAGATGGTCGATGTGACCGATAAGGATATCACCCA
GCGTGCGGCCACCGCGCAAGCGCGGGTGCGGATGCAGCCGAGCACCCTGCAAATGATCTTGGCTGGCGAGCACCCCAAGG
GTGATGTGCTTGCTACCGCACGGATTGCGGGCATTCAGGCAGCCAAAAAAACCTGGGACTTGATTCCACTGTGCCACCCG
CTGTTACTGACTGGGATCACGGTCACCATTGAGCCAGAGGCCGACGATGCGCTGTGTGTACAGGCGACCTGTAAGCTTAA
AGGTACTACCGGCGTGGAAATGGAGGCGCTAACGGCTGCGTCCGTTGCTTGCCTCACGCTGTATGACATGTGTAAGGCGG
TGGATCGCTGCATGGTGATTGAATCTGTGTGCCTGCTGGAAAAATCCGGTGGTCGTAGCGGGACGTTCCGGAGGGAAAGA
TAA

Upstream 100 bases:

>100_bases
CGGCCCAGGCGGGCTGATGACGGTACTTCATTCAATTCTGGAAAGGCGAGAATGGTAGCGCAGCGGCGCCACAGACAACA
GGGCGGAGACACCTCTGAGC

Downstream 100 bases:

>100_bases
AATGATTGAAATTCGTTTCTTTGCCGCTCTGCGTGAGCGGGTCGGCTGTGACAGCCTGACGGTCACTGCGCCGCAAGGCA
CCGACACGGTGACGGCGCTG

Product: molybdenum cofactor biosynthesis protein C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MTEQRFTHLDDSGRAQMVDVTDKDITQRAATAQARVRMQPSTLQMILAGEHPKGDVLATARIAGIQAAKKTWDLIPLCHP
LLLTGITVTIEPEADDALCVQATCKLKGTTGVEMEALTAASVACLTLYDMCKAVDRCMVIESVCLLEKSGGRSGTFRRER

Sequences:

>Translated_160_residues
MTEQRFTHLDDSGRAQMVDVTDKDITQRAATAQARVRMQPSTLQMILAGEHPKGDVLATARIAGIQAAKKTWDLIPLCHP
LLLTGITVTIEPEADDALCVQATCKLKGTTGVEMEALTAASVACLTLYDMCKAVDRCMVIESVCLLEKSGGRSGTFRRER
>Mature_159_residues
TEQRFTHLDDSGRAQMVDVTDKDITQRAATAQARVRMQPSTLQMILAGEHPKGDVLATARIAGIQAAKKTWDLIPLCHPL
LLTGITVTIEPEADDALCVQATCKLKGTTGVEMEALTAASVACLTLYDMCKAVDRCMVIESVCLLEKSGGRSGTFRRER

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=156, Percent_Identity=58.974358974359, Blast_Score=181, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=40.9395973154362, Blast_Score=120, Evalue=3e-28,
Organism=Drosophila melanogaster, GI28574490, Length=156, Percent_Identity=48.7179487179487, Blast_Score=130, Evalue=4e-31,
Organism=Drosophila melanogaster, GI28574492, Length=144, Percent_Identity=48.6111111111111, Blast_Score=117, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_ALCBS (Q0VQ23)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_692997.1
- ProteinModelPortal:   Q0VQ23
- SMR:   Q0VQ23
- STRING:   Q0VQ23
- GeneID:   4211355
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_1277
- NMPDR:   fig|393595.12.peg.1289
- eggNOG:   COG0315
- HOGENOM:   HBG605231
- OMA:   PMCHPLM
- PhylomeDB:   Q0VQ23
- BioCyc:   ABOR393595:ABO_1277-MONOMER
- HAMAP:   MF_01224_B
- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 17364; Mature: 17233

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: ACT_SITE 129-129

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
8.8 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
8.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQRFTHLDDSGRAQMVDVTDKDITQRAATAQARVRMQPSTLQMILAGEHPKGDVLATA
CCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHEEECCCCEEEEEECCCCCCCEEEEH
RIAGIQAAKKTWDLIPLCHPLLLTGITVTIEPEADDALCVQATCKLKGTTGVEMEALTAA
HHHHHHHHHHHHCHHHHHHHHHHCCEEEEECCCCCCEEEEEEEEEECCCCCCCHHHHHHH
SVACLTLYDMCKAVDRCMVIESVCLLEKSGGRSGTFRRER
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TEQRFTHLDDSGRAQMVDVTDKDITQRAATAQARVRMQPSTLQMILAGEHPKGDVLATA
CCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHEEECCCCEEEEEECCCCCCCEEEEH
RIAGIQAAKKTWDLIPLCHPLLLTGITVTIEPEADDALCVQATCKLKGTTGVEMEALTAA
HHHHHHHHHHHHCHHHHHHHHHHCCEEEEECCCCCCEEEEEEEEEECCCCCCCHHHHHHH
SVACLTLYDMCKAVDRCMVIESVCLLEKSGGRSGTFRRER
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA