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The map label for this gene is glcB [H]

Identifier: 110834128

GI number: 110834128

Start: 1442053

End: 1444212

Strand: Direct

Name: glcB [H]

Synonym: ABO_1267

Alternate gene names: 110834128

Gene position: 1442053-1444212 (Clockwise)

Preceding gene: 110834127

Following gene: 110834129

Centisome position: 46.22

GC content: 56.67

Gene sequence:

>2160_bases
ATGACCGATCGTATTCAGAAGGGTGGCCTTGAAATCGCCGCCGAACTCCATGATCTGGTAGTCAATGAGATTGCGCCGGG
TACCGGCGTCGACCCGGAGCACTTCTGGGCCGAGCTGGAAAGCATTCTTAATGACCTAGCCCCCAAAAACAAAGCGCTAC
TGGCCAAACGTGACGACCTGCAGAAGCAGATCGACGCTTGGCACAAGGCCCGCGTGGGGCAGGCCATCGACATGGCTGAG
TACAAGCAGTTTCTAACCGAAATTGGTTACCTGCTACCCGAGGGCGAAGACTTTAACATCACCACCGAAAACGTGGATGC
GGAAATTGCCACCATTGCTGGCCCGCAGCTGGTTGTGCCGGTGAAGAATGCACGCTTTGCCTTGAATGCGGCGAATGCTC
GGTGGGGTAGCTTATACGATGCCCTGTACGGCACCGATGTGATTTCCGACGAGGGGGGGGCCGAGAAAGGTGGCGCTTAC
AACCCGAAGCGCGGCGCCAAGGTGATTGCCTGGGCCCGTGACTTTTTGGATAATTACTTCCCGCTGGCCAGTGGCTCCCA
CAAAGACAGCACTGGCTACGCCATTGAAGACGGCAAGCTGGTTGTGTCTCTGGGCGAAGAGAAGACCGGCCTTAAAGACG
CATCTCAGCTTCAGGGTTTCCTGGGCGATGCCGCAGCCCCCACCGGGGTGCTGGTGAAGCACAACAATCTGCATGCGGAA
ATTCAGTTCGACGCCAGCCACCCGATTGGTGCTGACGACGCGGCCAACATGAAAGATGTGCTGCTAGAGTCTGCCATCAC
CACCATCCAGGATTGCGAAGACTCTGTCGCCGCTGTGGATGCGGAAGACAAAGTTGAGGTTTACCGCAACTGGGCTGGCC
TGATGAAAGGCGATTTGGAAGAGAGCTTCCAGAAAGGCGGCAAGACGATGACCCGTTCCATGAATGCGGATCGTGAGTAC
ACCGCGCTGGACGGTTCCTCCCTGACCCTGCACGGTCGTTCGTTGCTGCTGGTGCGTAACGTGGGTCACCTGATGACCAA
CCCGGCCATTCTGCACAACGGTGAAGAAACGCCTGAAGGGATTATGGATGGCATGGTCACTGTACTGGCCGCCATGCACG
ACCTGAAGAAAATCAACAAGCTGAGTAACAGCCGCACCGGTTCGGTCTACATTGTGAAGCCGAAAATGCACGGCCCGGAA
GAAGTGGCCTTTGCGGTTGAGCTATTTGAGCGCATAGAAAAAGCATTAGGTTTGGCCGCTAACACATTGAAAATTGGCAT
TATGGACGAAGAGCGCCGCACTACTGTGAACCTGAAGGAGTGTATCCGTCAGGCCAAGGATCGCGTTATCTTCATCAACA
CAGGCTTCCTCGATCGCACCGGTGACGAAATGCACACCTCCATGGAAGCGGGCCCCATGGCACCTAAAGGTGAGATGAAA
ACCCTGCCGTGGATTAGCGCCTACGAAGACTGGAACGTGGACATTGGCCTGGAATGCGGCCTGAAAGGTCACGCCCAGAT
CGGTAAAGGCATGTGGGCCATGCCCGATGAAATGGCACAGATGATGGCCAACAAGGCGGGTCACCCGAAAGCGGGCGCCA
ACTGTGCCTGGGTGCCGTCACCCACTGCCGCCACCCTGCACGTAACCCACTACCATGAGATCAACGTGGCCGAGGTTCAG
GAAAAGCTGGCCGGCCGTGCCCGCGCTTCTCTGGACGACATCCTCACCATTCCACTACTGACCCGTGAGCTGAGCGCTGA
AGAAATCCAGCAGGAGCTGGATAACAACGCGCAAGGCATGCTCGGCTACGTGGTTCGCTGGATCGATAGCGGTGTGGGCT
GCTCCAAGGTACCCGACATCAATGATGTGGGCCTCATGGAAGACCGTGCAACCCTGCGGATTTCCAGCCAGCATGTCGCT
AACTGGCTGCACCACGGTATCTGCAGTAAAGAACAGGTACTGGAAACCATGAAGCGGATGGCGGAAGTGGTAGATCGTCA
GAATGCCAATGATCCCGACTATGTGCCCATGGCCAAGGACTTCGACGGCTCCGTTGCCTTCCAGGCAGCCTGTGAGTTGG
TATTTGAAGGCTGCGCTCAACCAAGCGGCTACACCGAACCGGTTCTGCACCGTCGTCGCCGTGAACTGAAAGCGAAGTAA

Upstream 100 bases:

>100_bases
GATGATCCACACGGTAGCGCGCTGACGTAGACCTGTTGCCGGATTCTCTCTGAACGTCCCGATTAATCAAGATTCTCTCG
ACCAGAAGGGTAGGAGCACC

Downstream 100 bases:

>100_bases
CGCTTTCAGCACACAAAAAAGCCCCGCGAGTCGGGGCTTTTTTGTGTGTAAGCCTCAAGCCAGATGATGATTGCCGTGCC
GGCGGCTGGTGCTGAAAATT

Product: malate synthase G

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 719; Mature: 718

Protein sequence:

>719_residues
MTDRIQKGGLEIAAELHDLVVNEIAPGTGVDPEHFWAELESILNDLAPKNKALLAKRDDLQKQIDAWHKARVGQAIDMAE
YKQFLTEIGYLLPEGEDFNITTENVDAEIATIAGPQLVVPVKNARFALNAANARWGSLYDALYGTDVISDEGGAEKGGAY
NPKRGAKVIAWARDFLDNYFPLASGSHKDSTGYAIEDGKLVVSLGEEKTGLKDASQLQGFLGDAAAPTGVLVKHNNLHAE
IQFDASHPIGADDAANMKDVLLESAITTIQDCEDSVAAVDAEDKVEVYRNWAGLMKGDLEESFQKGGKTMTRSMNADREY
TALDGSSLTLHGRSLLLVRNVGHLMTNPAILHNGEETPEGIMDGMVTVLAAMHDLKKINKLSNSRTGSVYIVKPKMHGPE
EVAFAVELFERIEKALGLAANTLKIGIMDEERRTTVNLKECIRQAKDRVIFINTGFLDRTGDEMHTSMEAGPMAPKGEMK
TLPWISAYEDWNVDIGLECGLKGHAQIGKGMWAMPDEMAQMMANKAGHPKAGANCAWVPSPTAATLHVTHYHEINVAEVQ
EKLAGRARASLDDILTIPLLTRELSAEEIQQELDNNAQGMLGYVVRWIDSGVGCSKVPDINDVGLMEDRATLRISSQHVA
NWLHHGICSKEQVLETMKRMAEVVDRQNANDPDYVPMAKDFDGSVAFQAACELVFEGCAQPSGYTEPVLHRRRRELKAK

Sequences:

>Translated_719_residues
MTDRIQKGGLEIAAELHDLVVNEIAPGTGVDPEHFWAELESILNDLAPKNKALLAKRDDLQKQIDAWHKARVGQAIDMAE
YKQFLTEIGYLLPEGEDFNITTENVDAEIATIAGPQLVVPVKNARFALNAANARWGSLYDALYGTDVISDEGGAEKGGAY
NPKRGAKVIAWARDFLDNYFPLASGSHKDSTGYAIEDGKLVVSLGEEKTGLKDASQLQGFLGDAAAPTGVLVKHNNLHAE
IQFDASHPIGADDAANMKDVLLESAITTIQDCEDSVAAVDAEDKVEVYRNWAGLMKGDLEESFQKGGKTMTRSMNADREY
TALDGSSLTLHGRSLLLVRNVGHLMTNPAILHNGEETPEGIMDGMVTVLAAMHDLKKINKLSNSRTGSVYIVKPKMHGPE
EVAFAVELFERIEKALGLAANTLKIGIMDEERRTTVNLKECIRQAKDRVIFINTGFLDRTGDEMHTSMEAGPMAPKGEMK
TLPWISAYEDWNVDIGLECGLKGHAQIGKGMWAMPDEMAQMMANKAGHPKAGANCAWVPSPTAATLHVTHYHEINVAEVQ
EKLAGRARASLDDILTIPLLTRELSAEEIQQELDNNAQGMLGYVVRWIDSGVGCSKVPDINDVGLMEDRATLRISSQHVA
NWLHHGICSKEQVLETMKRMAEVVDRQNANDPDYVPMAKDFDGSVAFQAACELVFEGCAQPSGYTEPVLHRRRRELKAK
>Mature_718_residues
TDRIQKGGLEIAAELHDLVVNEIAPGTGVDPEHFWAELESILNDLAPKNKALLAKRDDLQKQIDAWHKARVGQAIDMAEY
KQFLTEIGYLLPEGEDFNITTENVDAEIATIAGPQLVVPVKNARFALNAANARWGSLYDALYGTDVISDEGGAEKGGAYN
PKRGAKVIAWARDFLDNYFPLASGSHKDSTGYAIEDGKLVVSLGEEKTGLKDASQLQGFLGDAAAPTGVLVKHNNLHAEI
QFDASHPIGADDAANMKDVLLESAITTIQDCEDSVAAVDAEDKVEVYRNWAGLMKGDLEESFQKGGKTMTRSMNADREYT
ALDGSSLTLHGRSLLLVRNVGHLMTNPAILHNGEETPEGIMDGMVTVLAAMHDLKKINKLSNSRTGSVYIVKPKMHGPEE
VAFAVELFERIEKALGLAANTLKIGIMDEERRTTVNLKECIRQAKDRVIFINTGFLDRTGDEMHTSMEAGPMAPKGEMKT
LPWISAYEDWNVDIGLECGLKGHAQIGKGMWAMPDEMAQMMANKAGHPKAGANCAWVPSPTAATLHVTHYHEINVAEVQE
KLAGRARASLDDILTIPLLTRELSAEEIQQELDNNAQGMLGYVVRWIDSGVGCSKVPDINDVGLMEDRATLRISSQHVAN
WLHHGICSKEQVLETMKRMAEVVDRQNANDPDYVPMAKDFDGSVAFQAACELVFEGCAQPSGYTEPVLHRRRRELKAK

Specific function: Accounts For Almost The Entire Malate-Synthesizing Activity In Cells Metabolizing Glyoxylate. [C]

COG id: COG2225

COG function: function code C; Malate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the malate synthase family. GlcB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789348, Length=721, Percent_Identity=58.6685159500693, Blast_Score=861, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17561814, Length=326, Percent_Identity=26.0736196319018, Blast_Score=76, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011076
- InterPro:   IPR001465
- InterPro:   IPR006253 [H]

Pfam domain/function: PF01274 Malate_synthase [H]

EC number: =2.3.3.9 [H]

Molecular weight: Translated: 78716; Mature: 78585

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRIQKGGLEIAAELHDLVVNEIAPGTGVDPEHFWAELESILNDLAPKNKALLAKRDDL
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
QKQIDAWHKARVGQAIDMAEYKQFLTEIGYLLPEGEDFNITTENVDAEIATIAGPQLVVP
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEEEECCCEEEEE
VKNARFALNAANARWGSLYDALYGTDVISDEGGAEKGGAYNPKRGAKVIAWARDFLDNYF
ECCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
PLASGSHKDSTGYAIEDGKLVVSLGEEKTGLKDASQLQGFLGDAAAPTGVLVKHNNLHAE
CCCCCCCCCCCCEEEECCEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCEEEEECCEEEE
IQFDASHPIGADDAANMKDVLLESAITTIQDCEDSVAAVDAEDKVEVYRNWAGLMKGDLE
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
ESFQKGGKTMTRSMNADREYTALDGSSLTLHGRSLLLVRNVGHLMTNPAILHNGEETPEG
HHHHHCCHHHHHCCCCCCCEEEECCCEEEECCCEEEEEEHHHHHHCCCCEEECCCCCHHH
IMDGMVTVLAAMHDLKKINKLSNSRTGSVYIVKPKMHGPEEVAFAVELFERIEKALGLAA
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCC
NTLKIGIMDEERRTTVNLKECIRQAKDRVIFINTGFLDRTGDEMHTSMEAGPMAPKGEMK
CEEEEEEECCCCCCEECHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHCCCCCCCCCCCC
TLPWISAYEDWNVDIGLECGLKGHAQIGKGMWAMPDEMAQMMANKAGHPKAGANCAWVPS
CCCCEECCCCCCCEEEEECCCCCCHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCEEECCC
PTAATLHVTHYHEINVAEVQEKLAGRARASLDDILTIPLLTRELSAEEIQQELDNNAQGM
CCCEEEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCHH
LGYVVRWIDSGVGCSKVPDINDVGLMEDRATLRISSQHVANWLHHGICSKEQVLETMKRM
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHCCCCHHHHHHHHHHH
AEVVDRQNANDPDYVPMAKDFDGSVAFQAACELVFEGCAQPSGYTEPVLHRRRRELKAK
HHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
TDRIQKGGLEIAAELHDLVVNEIAPGTGVDPEHFWAELESILNDLAPKNKALLAKRDDL
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
QKQIDAWHKARVGQAIDMAEYKQFLTEIGYLLPEGEDFNITTENVDAEIATIAGPQLVVP
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEEEECCCEEEEE
VKNARFALNAANARWGSLYDALYGTDVISDEGGAEKGGAYNPKRGAKVIAWARDFLDNYF
ECCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
PLASGSHKDSTGYAIEDGKLVVSLGEEKTGLKDASQLQGFLGDAAAPTGVLVKHNNLHAE
CCCCCCCCCCCCEEEECCEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCEEEEECCEEEE
IQFDASHPIGADDAANMKDVLLESAITTIQDCEDSVAAVDAEDKVEVYRNWAGLMKGDLE
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
ESFQKGGKTMTRSMNADREYTALDGSSLTLHGRSLLLVRNVGHLMTNPAILHNGEETPEG
HHHHHCCHHHHHCCCCCCCEEEECCCEEEECCCEEEEEEHHHHHHCCCCEEECCCCCHHH
IMDGMVTVLAAMHDLKKINKLSNSRTGSVYIVKPKMHGPEEVAFAVELFERIEKALGLAA
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCC
NTLKIGIMDEERRTTVNLKECIRQAKDRVIFINTGFLDRTGDEMHTSMEAGPMAPKGEMK
CEEEEEEECCCCCCEECHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHCCCCCCCCCCCC
TLPWISAYEDWNVDIGLECGLKGHAQIGKGMWAMPDEMAQMMANKAGHPKAGANCAWVPS
CCCCEECCCCCCCEEEEECCCCCCHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCEEECCC
PTAATLHVTHYHEINVAEVQEKLAGRARASLDDILTIPLLTRELSAEEIQQELDNNAQGM
CCCEEEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCHH
LGYVVRWIDSGVGCSKVPDINDVGLMEDRATLRISSQHVANWLHHGICSKEQVLETMKRM
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHCCCCHHHHHHHHHHH
AEVVDRQNANDPDYVPMAKDFDGSVAFQAACELVFEGCAQPSGYTEPVLHRRRRELKAK
HHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12534463 [H]