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The map label for this gene is gacS [H]

Identifier: 110834104

GI number: 110834104

Start: 1417726

End: 1419870

Strand: Direct

Name: gacS [H]

Synonym: ABO_1243

Alternate gene names: 110834104

Gene position: 1417726-1419870 (Clockwise)

Preceding gene: 110834103

Following gene: 110834105

Centisome position: 45.44

GC content: 54.69

Gene sequence:

>2145_bases
TTGATGGGAGTCCTGGCGGCCCTTCTGGTTTATGCAGTTGTCTTTACCTGGGGACAGGTCTACCAGAGCTTCGAACTGGA
AGCGCTAATAGGGGGGGGCGCCGTACTGCTCGTTACCGCTTACCGGTTATGGCTGGTGGCCCGTTTTGATGCCCTCCATG
GTTCTGGCCCCGCACGTTGGCGACGTTTGTTCGGGGTGGGCCTGTCGCTGCATGCTTTGTTGTGGGGCTTGCTACCAGCC
TGGCTAATTTGGCGATTGGGCACCGGCTTTAATTTCTTCGTAGTGATTCTTTATAACGTCGGCGTAACGACGGCCCTAGG
CAGCTCCTGGATGGCCGGCTTACGGGTGCGCCAAGCGTATATCGTACTGATGTTTCTGCCGACATTGGCGGTATTACTGT
TTGCGGGAAGCGTGCACGATTGGGTTTTGGCGGCATTGATTGGCTCCTATGCATTTTACTTGTTCCGCCTTTACCGCGGG
CAGTACGAGACATTCTGGCATGCCATGACCCGTGAGCGGCGGGGCTCTGTGGAGCCTAAAAAGCCGGTGCGCAGTAGTAC
CGAAGTGCAGCTGAGTTTAGTGTACCGACTGGCCCACGAACTACGCACGCCGATGAATTCGTTGATGGGTATGATGTCGT
TGCTAGAAGACACCCGCCTGAATGACGAACAAAAAGACTACCTACAAGTGGCAGGGCAGAGTGGCAAGTTGCTGCTGACT
CTGATTGATGACGTTCTGGATTATTCCCGCATTCTTTCCCGCCGCATTACCCTTAACTCTGATTATTTTGACTTTCGGGC
AGCGATTGAACAGTCGCTGGAAGCCTTCGGGCCCATGGCCCAGACATCCGGTCTGGAATTGACCTGTGTGATTGACCGGA
TGTTGCCCAAGCGTATTCGCGGTGATCGTGAGCGGTTGATGCAGGTACTTAATAACCTGTTCAGCAATGCCATCAAATTC
AGTGAAAAGGGTGAAATTCGTCTCGATGTGGATTTTACTGTGGAGAGGGAAAACGCTGGTGTGCTCAGGGTGCGGGTTAG
CGACGAAGGCGCAGGCATGGACCCGGAAACCTTGCGCCACTTGTTCCAAGATCGCTTTATTGAAGAGGGGCAGGACGTCT
ACAGCAGCCATCATACTGGTTTCGGTTTGCTGGTCTGTAAGGGGCTAATTGATGCTATGGGGGGCACACTGGGCGCAGAA
AGCGTGCCTGGCGAAGGCTCTACTTTCTGGTTCACCGTGCCGGTGCAAATGCAGCCGGATATGCGCGAAGCCCAGAGTTT
GATACGGGCGCTAGATGGCGTCCAGGCCTTGGTGGTTGGCGCTGCCTCGGGCACGGTTTCGAGTATCCAGGAAGAATTAG
AAGCGCTGGGTTGTCAGGCTTCCTCTGCGATGGGGTATGACCATGCACTTCAAGCTTTGCGTGCGGGGCATCGTGAGCAA
AGTGACTTTGATGTATTGTTTGTTGATACCTGGTCACGGGGAGAGTTGGCGCTGAATCTATGCCGTAACGTACTTGAAGA
TCCCTCGCTACGTCCGGTACGTCTTGTGCTTTTGGCCACCATTGAAGAGCGTAGCCATGCGGCAGTGCAACAGCTAATCG
ATAAACATGATCTGGTGGTGCTGGTACGGCCAGTACATCGCAGCGTATTGCGCCAGGGCTTGGCAAGGTTGATGGGGCTG
CAACGGCAAATTCCAGTTGGTGATGCTCCTCTTCAGACGCCGGAAGAGCGGCAGCGCCGCAAACGCTTCCGGCTGATGCT
GGTGGAGGACAACGAAGTGAATCAGCTGGTTACCCGGGGCATGCTAAGTAAGTTGGGCTATCAGGTAAAAACCGTGAGCA
ACGGTGAAACGGCACTGGCGTTGCTGGAACAAGAACCCTTTGATCTGGTGTTGATGGATTGCATGATGCCGGAGATGGAT
GGCTTTGAAGCAACCCGTCGCCAGCGAGAAATGGAACACAGCAAAGCGAGCCCGCGTACCCCGATTGTTGCGATTACCGC
CAATACCGCGGAAGGCGTTCAGGCCCGTTGCCTAGCTGCTGGCATGGATGATTTTCTTGCCAAACCGGTGCATCTTGATG
CACTAGAAACAGTATTGCGCCGCTGGCTGCCCGAGCAGCCCGTCAGAGATGAGGATGAACAATGA

Upstream 100 bases:

>100_bases
CGAAACCGGTTTTCCCGTTTCTTCGGAACAAAACACAGTGTCATACAAGAAAGATCGAAAGGTTCTTAAACGCGTAGATT
ATGGGGCCGCCAAGAACTCC

Downstream 100 bases:

>100_bases
CAAGAAAAGCCTTGCTGCTGGGAGCAACCGGGTTAGTGGGTCGTGATTGCTTAGAAAACCTACTTGCCTGCGATGACTAT
GAAAAGGTAATTGTGCTGAC

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 714; Mature: 714

Protein sequence:

>714_residues
MMGVLAALLVYAVVFTWGQVYQSFELEALIGGGAVLLVTAYRLWLVARFDALHGSGPARWRRLFGVGLSLHALLWGLLPA
WLIWRLGTGFNFFVVILYNVGVTTALGSSWMAGLRVRQAYIVLMFLPTLAVLLFAGSVHDWVLAALIGSYAFYLFRLYRG
QYETFWHAMTRERRGSVEPKKPVRSSTEVQLSLVYRLAHELRTPMNSLMGMMSLLEDTRLNDEQKDYLQVAGQSGKLLLT
LIDDVLDYSRILSRRITLNSDYFDFRAAIEQSLEAFGPMAQTSGLELTCVIDRMLPKRIRGDRERLMQVLNNLFSNAIKF
SEKGEIRLDVDFTVERENAGVLRVRVSDEGAGMDPETLRHLFQDRFIEEGQDVYSSHHTGFGLLVCKGLIDAMGGTLGAE
SVPGEGSTFWFTVPVQMQPDMREAQSLIRALDGVQALVVGAASGTVSSIQEELEALGCQASSAMGYDHALQALRAGHREQ
SDFDVLFVDTWSRGELALNLCRNVLEDPSLRPVRLVLLATIEERSHAAVQQLIDKHDLVVLVRPVHRSVLRQGLARLMGL
QRQIPVGDAPLQTPEERQRRKRFRLMLVEDNEVNQLVTRGMLSKLGYQVKTVSNGETALALLEQEPFDLVLMDCMMPEMD
GFEATRRQREMEHSKASPRTPIVAITANTAEGVQARCLAAGMDDFLAKPVHLDALETVLRRWLPEQPVRDEDEQ

Sequences:

>Translated_714_residues
MMGVLAALLVYAVVFTWGQVYQSFELEALIGGGAVLLVTAYRLWLVARFDALHGSGPARWRRLFGVGLSLHALLWGLLPA
WLIWRLGTGFNFFVVILYNVGVTTALGSSWMAGLRVRQAYIVLMFLPTLAVLLFAGSVHDWVLAALIGSYAFYLFRLYRG
QYETFWHAMTRERRGSVEPKKPVRSSTEVQLSLVYRLAHELRTPMNSLMGMMSLLEDTRLNDEQKDYLQVAGQSGKLLLT
LIDDVLDYSRILSRRITLNSDYFDFRAAIEQSLEAFGPMAQTSGLELTCVIDRMLPKRIRGDRERLMQVLNNLFSNAIKF
SEKGEIRLDVDFTVERENAGVLRVRVSDEGAGMDPETLRHLFQDRFIEEGQDVYSSHHTGFGLLVCKGLIDAMGGTLGAE
SVPGEGSTFWFTVPVQMQPDMREAQSLIRALDGVQALVVGAASGTVSSIQEELEALGCQASSAMGYDHALQALRAGHREQ
SDFDVLFVDTWSRGELALNLCRNVLEDPSLRPVRLVLLATIEERSHAAVQQLIDKHDLVVLVRPVHRSVLRQGLARLMGL
QRQIPVGDAPLQTPEERQRRKRFRLMLVEDNEVNQLVTRGMLSKLGYQVKTVSNGETALALLEQEPFDLVLMDCMMPEMD
GFEATRRQREMEHSKASPRTPIVAITANTAEGVQARCLAAGMDDFLAKPVHLDALETVLRRWLPEQPVRDEDEQ
>Mature_714_residues
MMGVLAALLVYAVVFTWGQVYQSFELEALIGGGAVLLVTAYRLWLVARFDALHGSGPARWRRLFGVGLSLHALLWGLLPA
WLIWRLGTGFNFFVVILYNVGVTTALGSSWMAGLRVRQAYIVLMFLPTLAVLLFAGSVHDWVLAALIGSYAFYLFRLYRG
QYETFWHAMTRERRGSVEPKKPVRSSTEVQLSLVYRLAHELRTPMNSLMGMMSLLEDTRLNDEQKDYLQVAGQSGKLLLT
LIDDVLDYSRILSRRITLNSDYFDFRAAIEQSLEAFGPMAQTSGLELTCVIDRMLPKRIRGDRERLMQVLNNLFSNAIKF
SEKGEIRLDVDFTVERENAGVLRVRVSDEGAGMDPETLRHLFQDRFIEEGQDVYSSHHTGFGLLVCKGLIDAMGGTLGAE
SVPGEGSTFWFTVPVQMQPDMREAQSLIRALDGVQALVVGAASGTVSSIQEELEALGCQASSAMGYDHALQALRAGHREQ
SDFDVLFVDTWSRGELALNLCRNVLEDPSLRPVRLVLLATIEERSHAAVQQLIDKHDLVVLVRPVHRSVLRQGLARLMGL
QRQIPVGDAPLQTPEERQRRKRFRLMLVEDNEVNQLVTRGMLSKLGYQVKTVSNGETALALLEQEPFDLVLMDCMMPEMD
GFEATRRQREMEHSKASPRTPIVAITANTAEGVQARCLAAGMDDFLAKPVHLDALETVLRRWLPEQPVRDEDEQ

Specific function: Forms part of a two-component regulatory system gacA/gacS(lemA). May be involved in lesion formation, swarming and in the production of extracellular protease, syringomycin and N- acyl-L-homoserine lactone (acyl-HSL). Required for pathogenicity on bean [H

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=530, Percent_Identity=28.3018867924528, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI145693157, Length=509, Percent_Identity=28.2907662082515, Blast_Score=190, Evalue=3e-49,
Organism=Escherichia coli, GI1788713, Length=244, Percent_Identity=31.1475409836066, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI87081816, Length=400, Percent_Identity=28.75, Blast_Score=129, Evalue=8e-31,
Organism=Escherichia coli, GI48994928, Length=323, Percent_Identity=26.9349845201238, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1786912, Length=242, Percent_Identity=28.099173553719, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790436, Length=223, Percent_Identity=28.6995515695067, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1788549, Length=230, Percent_Identity=26.5217391304348, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788393, Length=222, Percent_Identity=25.6756756756757, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1788550, Length=128, Percent_Identity=32.03125, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI87082012, Length=114, Percent_Identity=31.5789473684211, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786783, Length=220, Percent_Identity=25.9090909090909, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789809, Length=139, Percent_Identity=31.6546762589928, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=386, Percent_Identity=25.1295336787565, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6322000, Length=124, Percent_Identity=40.3225806451613, Blast_Score=85, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 80110; Mature: 80110

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMGVLAALLVYAVVFTWGQVYQSFELEALIGGGAVLLVTAYRLWLVARFDALHGSGPARW
CHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHH
RRLFGVGLSLHALLWGLLPAWLIWRLGTGFNFFVVILYNVGVTTALGSSWMAGLRVRQAY
HHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHCCHHHHHHHHHHHHHHHHHHH
IVLMFLPTLAVLLFAGSVHDWVLAALIGSYAFYLFRLYRGQYETFWHAMTRERRGSVEPK
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCC
KPVRSSTEVQLSLVYRLAHELRTPMNSLMGMMSLLEDTRLNDEQKDYLQVAGQSGKLLLT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHH
LIDDVLDYSRILSRRITLNSDYFDFRAAIEQSLEAFGPMAQTSGLELTCVIDRMLPKRIR
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHC
GDRERLMQVLNNLFSNAIKFSEKGEIRLDVDFTVERENAGVLRVRVSDEGAGMDPETLRH
CCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCCEEEEEECCCCCCCCHHHHHH
LFQDRFIEEGQDVYSSHHTGFGLLVCKGLIDAMGGTLGAESVPGEGSTFWFTVPVQMQPD
HHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEECCC
MREAQSLIRALDGVQALVVGAASGTVSSIQEELEALGCQASSAMGYDHALQALRAGHREQ
HHHHHHHHHHHCCHHEEEEECCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCC
SDFDVLFVDTWSRGELALNLCRNVLEDPSLRPVRLVLLATIEERSHAAVQQLIDKHDLVV
CCCEEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
LVRPVHRSVLRQGLARLMGLQRQIPVGDAPLQTPEERQRRKRFRLMLVEDNEVNQLVTRG
EEHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCHHHHHHHHHEEEEECCCHHHHHHHHH
MLSKLGYQVKTVSNGETALALLEQEPFDLVLMDCMMPEMDGFEATRRQREMEHSKASPRT
HHHHCCCEEEEECCCCCEEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCC
PIVAITANTAEGVQARCLAAGMDDFLAKPVHLDALETVLRRWLPEQPVRDEDEQ
CEEEEECCCCCCHHHHHHHHCHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MMGVLAALLVYAVVFTWGQVYQSFELEALIGGGAVLLVTAYRLWLVARFDALHGSGPARW
CHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHH
RRLFGVGLSLHALLWGLLPAWLIWRLGTGFNFFVVILYNVGVTTALGSSWMAGLRVRQAY
HHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHCCHHHHHHHHHHHHHHHHHHH
IVLMFLPTLAVLLFAGSVHDWVLAALIGSYAFYLFRLYRGQYETFWHAMTRERRGSVEPK
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCC
KPVRSSTEVQLSLVYRLAHELRTPMNSLMGMMSLLEDTRLNDEQKDYLQVAGQSGKLLLT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHH
LIDDVLDYSRILSRRITLNSDYFDFRAAIEQSLEAFGPMAQTSGLELTCVIDRMLPKRIR
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHC
GDRERLMQVLNNLFSNAIKFSEKGEIRLDVDFTVERENAGVLRVRVSDEGAGMDPETLRH
CCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCCEEEEEECCCCCCCCHHHHHH
LFQDRFIEEGQDVYSSHHTGFGLLVCKGLIDAMGGTLGAESVPGEGSTFWFTVPVQMQPD
HHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEECCC
MREAQSLIRALDGVQALVVGAASGTVSSIQEELEALGCQASSAMGYDHALQALRAGHREQ
HHHHHHHHHHHCCHHEEEEECCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCC
SDFDVLFVDTWSRGELALNLCRNVLEDPSLRPVRLVLLATIEERSHAAVQQLIDKHDLVV
CCCEEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
LVRPVHRSVLRQGLARLMGLQRQIPVGDAPLQTPEERQRRKRFRLMLVEDNEVNQLVTRG
EEHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCHHHHHHHHHEEEEECCCHHHHHHHHH
MLSKLGYQVKTVSNGETALALLEQEPFDLVLMDCMMPEMDGFEATRRQREMEHSKASPRT
HHHHCCCEEEEECCCCCEEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCC
PIVAITANTAEGVQARCLAAGMDDFLAKPVHLDALETVLRRWLPEQPVRDEDEQ
CEEEEECCCCCCHHHHHHHHCHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1314807 [H]