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The map label for this gene is nfuA [H]

Identifier: 110834051

GI number: 110834051

Start: 1351538

End: 1352134

Strand: Direct

Name: nfuA [H]

Synonym: ABO_1190

Alternate gene names: 110834051

Gene position: 1351538-1352134 (Clockwise)

Preceding gene: 110834047

Following gene: 110834054

Centisome position: 43.32

GC content: 52.76

Gene sequence:

>597_bases
ATGATGGCAGAGCAGTTGATCGACATTACCGAAACCGCCCAGGATTACTTGCGTGACTTGCTAAGCAAGCAGGATCAGGC
AGAGATTGGTGTGCGTATCTTTGTCGAGCGTCCAGGTACGCCGCACGCAGAGTGCTGTATGGCGTATTGCCCGGAGGGCG
AGCAGGAAGAAAGCGATGTTCGCTACGATTATGAAGGGTTTCATGCTTGGATTGAGGGAAAAAGCGTTCGCTATCTCGAA
GATGCGGTAATCGACTACAAGAAAGATAGCATGGGCGGACAGCTCACTTTCCGAGCGCCTAAGTCTCGGGTGCCGGATAT
CAGTGAAGACGCGACTATCGAAGAGAAGATTAATTACGTGCTTTACGCTGAGATCAACCCTAACTTGGCAGCCCACGGTG
GTAGTGTGCAGTTGTTGGAACTGACCGATGATAATGTGGCTGTTTTGGAATTTGGCGGAGGCTGCCAGGGCTGCTCTGTG
GTAGATGTGACCCTGCGTGACGGGGTGGAGAAAACCCTCCAGGAGCGGATTCCGGAACTCGCCGGCGTTCGCGACAAGAC
CGACCATACCGTGACGGATAACGCATATTACAGTTAA

Upstream 100 bases:

>100_bases
TACCTGACTAAAATAGTCAGGAAAGAAAGCTTGCGTACGTCGCTGCTTTACCTTTTACGCTTTTTGTTGCGTATGGGTTC
ATTCATCTCAACCAGGAATT

Downstream 100 bases:

>100_bases
CAGGTAAGCTTCTAGCTACAAAAAAACCGCGCCCGAAAGGGTGCGGTTTTTTTGTTTCAAGCCGTGGCTCAGCGTGAGGC
TCGGCATTTCTAGCAAGAGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MMAEQLIDITETAQDYLRDLLSKQDQAEIGVRIFVERPGTPHAECCMAYCPEGEQEESDVRYDYEGFHAWIEGKSVRYLE
DAVIDYKKDSMGGQLTFRAPKSRVPDISEDATIEEKINYVLYAEINPNLAAHGGSVQLLELTDDNVAVLEFGGGCQGCSV
VDVTLRDGVEKTLQERIPELAGVRDKTDHTVTDNAYYS

Sequences:

>Translated_198_residues
MMAEQLIDITETAQDYLRDLLSKQDQAEIGVRIFVERPGTPHAECCMAYCPEGEQEESDVRYDYEGFHAWIEGKSVRYLE
DAVIDYKKDSMGGQLTFRAPKSRVPDISEDATIEEKINYVLYAEINPNLAAHGGSVQLLELTDDNVAVLEFGGGCQGCSV
VDVTLRDGVEKTLQERIPELAGVRDKTDHTVTDNAYYS
>Mature_198_residues
MMAEQLIDITETAQDYLRDLLSKQDQAEIGVRIFVERPGTPHAECCMAYCPEGEQEESDVRYDYEGFHAWIEGKSVRYLE
DAVIDYKKDSMGGQLTFRAPKSRVPDISEDATIEEKINYVLYAEINPNLAAHGGSVQLLELTDDNVAVLEFGGGCQGCSV
VDVTLRDGVEKTLQERIPELAGVRDKTDHTVTDNAYYS

Specific function: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins [H]

COG id: COG0694

COG function: function code O; Thioredoxin-like proteins and domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nfuA family [H]

Homologues:

Organism=Escherichia coli, GI1789819, Length=192, Percent_Identity=44.7916666666667, Blast_Score=190, Evalue=4e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017726
- InterPro:   IPR000361
- InterPro:   IPR001075
- ProDom:   PD002830 [H]

Pfam domain/function: PF01521 Fe-S_biosyn; PF01106 NifU [H]

EC number: NA

Molecular weight: Translated: 22134; Mature: 22134

Theoretical pI: Translated: 4.13; Mature: 4.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMAEQLIDITETAQDYLRDLLSKQDQAEIGVRIFVERPGTPHAECCMAYCPEGEQEESDV
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCC
RYDYEGFHAWIEGKSVRYLEDAVIDYKKDSMGGQLTFRAPKSRVPDISEDATIEEKINYV
CCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHCCEE
LYAEINPNLAAHGGSVQLLELTDDNVAVLEFGGGCQGCSVVDVTLRDGVEKTLQERIPEL
EEEEECCCEEECCCCEEEEEECCCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHH
AGVRDKTDHTVTDNAYYS
HCCCCCCCCEECCCCCCC
>Mature Secondary Structure
MMAEQLIDITETAQDYLRDLLSKQDQAEIGVRIFVERPGTPHAECCMAYCPEGEQEESDV
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCC
RYDYEGFHAWIEGKSVRYLEDAVIDYKKDSMGGQLTFRAPKSRVPDISEDATIEEKINYV
CCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHCCEE
LYAEINPNLAAHGGSVQLLELTDDNVAVLEFGGGCQGCSVVDVTLRDGVEKTLQERIPEL
EEEEECCCEEECCCCEEEEEECCCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHH
AGVRDKTDHTVTDNAYYS
HCCCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA