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The map label for this gene is nqrA

Identifier: 110833893

GI number: 110833893

Start: 1172889

End: 1174235

Strand: Direct

Name: nqrA

Synonym: ABO_1032

Alternate gene names: 110833893

Gene position: 1172889-1174235 (Clockwise)

Preceding gene: 110833892

Following gene: 110833894

Centisome position: 37.59

GC content: 55.23

Gene sequence:

>1347_bases
ATGATTAAAATCAGGAAGGGCCTTGATCTGCCCATCGCTGGTGCACCGCGCCAGGCGATTGAGGAAGGTCACCAGGTTCG
TTCTGTTGCCGTGCTCGGCGGTGACTATGTGGGCATGAAACCCACTATGGAAGTCCGCGAGGGAGACGTGGTCAAAAAAG
GCCAGCTGATCTTCACGGATAAGAAAACCGAGGGTGTGAAATATACATCTCCTGCTGCCGGTAAAGTGATTGCCATTAAC
CGTGGCCACAAACGAGTGCTTCAATCTGTGGTGATTGAAGTGGCAGACCAGGAAGACGAAGTCACCTTCGCCTCTTACAG
TGCTGACCAACTGAGATCTCTGGATCGCGATGCGGTGCAGCAGCAGTTGGTGGACTCCGGTGAGTGGACGCTGCTGCGCA
CTCGCCCATTCGGCAAGGTGCCGGCACCGGGTAGTACACCCAATTCTGTTTTCGTCTCTATCCTTGACACCAACCCTCTG
GCACTAGATCCGGCTGTGGTGATCAAGGAAAATGAGCAGGCTTTTCGCCATGGTTTGACTGTACTGAGCCGTCTGACCGA
CGGCCCGGTATGGGTGTGTCGCGGTCCTAATACTGATCTGCCCAGCTTTGCGGGCGGGCAGGTTCGTGAAGAAGCGTTTT
CTGGTAAGCATCCGGCAGGCAATGTGGGTACCCACATTCACTATCTAGACCCTGTTGGCCTGAACAAGACAGTTTGGTCG
GTGGGTTATCAGGATGTGATTGCTATCGGCAAGCTGTTCACCGAAGGCAAGATTAGTTCCGCCCGTGTGGTTGCCTTGAC
AGGCCCGCAGGCGAAAACTCCACGGGCCTTACGTACTCGTGTGGGCGCCAGCGTGGACGATTTTGCCCAGGGTGAACTAA
AAGAGGGCGATAACCGCCTGATCTCCGGCTCTGTGCTGAACGGTCACAACGCCCGAGGTCCTGTGGCTTGGTTAAGCCGG
ACAACAAACCAGCTAACGGCTTTGCGTGAAGGCCATGAACGGGAGCTGTTGGGTTACATTTCGCCCGGCGCCAACCGTTT
CTCGCTGATGAATATCTATCTGTCCAAGCTGATGCCGGGCAAACGCTTCAATTTTACCACTACTACCAATGGCTCCGAAC
GTGCCATGGTGCCAGTGGGGGCCTATGAAGAAGTGATGCCGCTGGATATTTTGCCGACGCAGTTGCTGCGTGCATTGATT
GTTGGTGATACCGACAGCGCCACGGCCCTTGGTGCCTTGGAGTTGCTGGAAGAAGACCTTTCTCTGTGTACCTTCGTGTG
CCCAGGCAAATACGAATACGGTCCGATTCTGCGCGACAACCTGACCACGATTGAGGCGGAGGGCTGA

Upstream 100 bases:

>100_bases
ACATTCCGGAATTTGCGAACGTTTCCTGTAAAACCTGGTTTACCCGGGCCCTCAGGTAGCGTGCCTCGACTTCAGCAACA
TGCAACGTGGGCGAGAAACT

Downstream 100 bases:

>100_bases
GCATGGGTATGAGAAAGTTTCTAGATGACAAAGTGTCCCCTCATTTTCATGAGGGTGGTAAGTTCGAGAAGTATTACACC
TTCTACGAAATGTTCGACAC

Product: Na(+)-translocating NADH-quinone reductase subunit A

Products: NA

Alternate protein names: Na(+)-NQR subunit A; Na(+)-translocating NQR subunit A; NQR complex subunit A; NQR-1 subunit A

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MIKIRKGLDLPIAGAPRQAIEEGHQVRSVAVLGGDYVGMKPTMEVREGDVVKKGQLIFTDKKTEGVKYTSPAAGKVIAIN
RGHKRVLQSVVIEVADQEDEVTFASYSADQLRSLDRDAVQQQLVDSGEWTLLRTRPFGKVPAPGSTPNSVFVSILDTNPL
ALDPAVVIKENEQAFRHGLTVLSRLTDGPVWVCRGPNTDLPSFAGGQVREEAFSGKHPAGNVGTHIHYLDPVGLNKTVWS
VGYQDVIAIGKLFTEGKISSARVVALTGPQAKTPRALRTRVGASVDDFAQGELKEGDNRLISGSVLNGHNARGPVAWLSR
TTNQLTALREGHERELLGYISPGANRFSLMNIYLSKLMPGKRFNFTTTTNGSERAMVPVGAYEEVMPLDILPTQLLRALI
VGDTDSATALGALELLEEDLSLCTFVCPGKYEYGPILRDNLTTIEAEG

Sequences:

>Translated_448_residues
MIKIRKGLDLPIAGAPRQAIEEGHQVRSVAVLGGDYVGMKPTMEVREGDVVKKGQLIFTDKKTEGVKYTSPAAGKVIAIN
RGHKRVLQSVVIEVADQEDEVTFASYSADQLRSLDRDAVQQQLVDSGEWTLLRTRPFGKVPAPGSTPNSVFVSILDTNPL
ALDPAVVIKENEQAFRHGLTVLSRLTDGPVWVCRGPNTDLPSFAGGQVREEAFSGKHPAGNVGTHIHYLDPVGLNKTVWS
VGYQDVIAIGKLFTEGKISSARVVALTGPQAKTPRALRTRVGASVDDFAQGELKEGDNRLISGSVLNGHNARGPVAWLSR
TTNQLTALREGHERELLGYISPGANRFSLMNIYLSKLMPGKRFNFTTTTNGSERAMVPVGAYEEVMPLDILPTQLLRALI
VGDTDSATALGALELLEEDLSLCTFVCPGKYEYGPILRDNLTTIEAEG
>Mature_448_residues
MIKIRKGLDLPIAGAPRQAIEEGHQVRSVAVLGGDYVGMKPTMEVREGDVVKKGQLIFTDKKTEGVKYTSPAAGKVIAIN
RGHKRVLQSVVIEVADQEDEVTFASYSADQLRSLDRDAVQQQLVDSGEWTLLRTRPFGKVPAPGSTPNSVFVSILDTNPL
ALDPAVVIKENEQAFRHGLTVLSRLTDGPVWVCRGPNTDLPSFAGGQVREEAFSGKHPAGNVGTHIHYLDPVGLNKTVWS
VGYQDVIAIGKLFTEGKISSARVVALTGPQAKTPRALRTRVGASVDDFAQGELKEGDNRLISGSVLNGHNARGPVAWLSR
TTNQLTALREGHERELLGYISPGANRFSLMNIYLSKLMPGKRFNFTTTTNGSERAMVPVGAYEEVMPLDILPTQLLRALI
VGDTDSATALGALELLEEDLSLCTFVCPGKYEYGPILRDNLTTIEAEG

Specific function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiqui

COG id: COG1726

COG function: function code C; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nqrA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NQRA_ALCBS (Q0VQR8)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_692752.1
- STRING:   Q0VQR8
- GeneID:   4211663
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_1032
- NMPDR:   fig|393595.12.peg.1040
- eggNOG:   COG1726
- HOGENOM:   HBG413878
- OMA:   EYGPILR
- ProtClustDB:   PRK05352
- BioCyc:   ABOR393595:ABO_1032-MONOMER
- HAMAP:   MF_00425
- InterPro:   IPR008703
- InterPro:   IPR022615
- TIGRFAMs:   TIGR01936

Pfam domain/function: PF05896 NQRA; PF11973 NQRA_SLBB

EC number: NA

Molecular weight: Translated: 48493; Mature: 48493

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKIRKGLDLPIAGAPRQAIEEGHQVRSVAVLGGDYVGMKPTMEVREGDVVKKGQLIFTD
CEEECCCCCCCCCCCCHHHHHCCHHEEEEEEECCCEECCCCCCCCCCCCEEECCEEEEEC
KKTEGVKYTSPAAGKVIAINRGHKRVLQSVVIEVADQEDEVTFASYSADQLRSLDRDAVQ
CCCCCEEEECCCCCEEEEEECCHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHCCHHHHH
QQLVDSGEWTLLRTRPFGKVPAPGSTPNSVFVSILDTNPLALDPAVVIKENEQAFRHGLT
HHHHCCCCEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCEECCEEEEECCHHHHHHHHH
VLSRLTDGPVWVCRGPNTDLPSFAGGQVREEAFSGKHPAGNVGTHIHYLDPVGLNKTVWS
HHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHH
VGYQDVIAIGKLFTEGKISSARVVALTGPQAKTPRALRTRVGASVDDFAQGELKEGDNRL
CCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHCCCHHHHCCCCCCCCCCEE
ISGSVLNGHNARGPVAWLSRTTNQLTALREGHERELLGYISPGANRFSLMNIYLSKLMPG
EECEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCC
KRFNFTTTTNGSERAMVPVGAYEEVMPLDILPTQLLRALIVGDTDSATALGALELLEEDL
CCEEEEECCCCCCEEEEECCCHHHCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
SLCTFVCPGKYEYGPILRDNLTTIEAEG
HHEEEECCCCCCCCCEECCCCCEEEECC
>Mature Secondary Structure
MIKIRKGLDLPIAGAPRQAIEEGHQVRSVAVLGGDYVGMKPTMEVREGDVVKKGQLIFTD
CEEECCCCCCCCCCCCHHHHHCCHHEEEEEEECCCEECCCCCCCCCCCCEEECCEEEEEC
KKTEGVKYTSPAAGKVIAINRGHKRVLQSVVIEVADQEDEVTFASYSADQLRSLDRDAVQ
CCCCCEEEECCCCCEEEEEECCHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHCCHHHHH
QQLVDSGEWTLLRTRPFGKVPAPGSTPNSVFVSILDTNPLALDPAVVIKENEQAFRHGLT
HHHHCCCCEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCEECCEEEEECCHHHHHHHHH
VLSRLTDGPVWVCRGPNTDLPSFAGGQVREEAFSGKHPAGNVGTHIHYLDPVGLNKTVWS
HHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHH
VGYQDVIAIGKLFTEGKISSARVVALTGPQAKTPRALRTRVGASVDDFAQGELKEGDNRL
CCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHCCCHHHHCCCCCCCCCCEE
ISGSVLNGHNARGPVAWLSRTTNQLTALREGHERELLGYISPGANRFSLMNIYLSKLMPG
EECEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCC
KRFNFTTTTNGSERAMVPVGAYEEVMPLDILPTQLLRALIVGDTDSATALGALELLEEDL
CCEEEEECCCCCCEEEEECCCHHHCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
SLCTFVCPGKYEYGPILRDNLTTIEAEG
HHEEEECCCCCCCCCEECCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA