Click here to switch to the map view.

The map label for this gene is tesB [H]

Identifier: 110833890

GI number: 110833890

Start: 1169510

End: 1170388

Strand: Direct

Name: tesB [H]

Synonym: ABO_1029

Alternate gene names: 110833890

Gene position: 1169510-1170388 (Clockwise)

Preceding gene: 110833887

Following gene: 110833891

Centisome position: 37.48

GC content: 55.29

Gene sequence:

>879_bases
ATGAAGGCATCGGTTCAGGAACTGATGAATCTGTTCGATTTGGAGCAGCTGGAGAATAATTTGTTTCGGGGACAAAGCGA
GGCCAATGGGCAGCGCAGTGTGTTTGGTGGCTTGGTGGCTGGGCAGGCGTTGTTGGCCGCCTCGCGGACGGTGGATGATG
CACGTCCTGTGCACTCCTTGCATGCGTATTTTTTGCGCCCCGGCGATTTTAACGTGCCGATTGTCTATTACGTTGACCGG
ATACGTGATGGCAAGAGTTTCACCACGCGCCGAGTGGACGCGATCCAGCATGGTCGGCCGATCTTCTCTCTGGCGGCGTC
TTACCAAGTGGCGGAGGAGGGGGTTTCCCATCAGTCAGTTATGCCCGACGTGCCGGGGCCTGAGGGCCTAGAGAATGATG
AGGGCATTCGTATGAAGCTGGTGGATCGCTTGCCTGAACAGTTTCGAAAGGATTTTCTGACTGACCGGCCGGTAGAGTTT
CGGCCGGTGACGCCGAAAGATTCCATCTCCTCTGAACCCCAGGACCCTGTCCGCGAGGTTTGGTTCAGGGTGGTAGATCG
GGTGGATGCTAACCCGATGACCCAGCGAGCGTTATTAGCCTATTGTTCCGACTTTGGCCTAATGGGCACCGCCATGCTGC
CTCACGGAATGAATTTCTGGCAGCCTAATGTGCAGTGCGCGAGCATTGATCATGCCATGTGGTTCCATAATGATTTTCGC
ATTGATGAGTGGCTGCTGTATCGAAGTGATAGCCCCTTCTCGGGTGGTTCTCGCGGCCTGAATTTTGGTTCTATTTATCG
CCAAGATGGCACCTTGGTGGCGTCGGTGGCTCAAGAAGGATTGATGCGCCTGCATCCCTCAGACAGCCCGACGGAATGA

Upstream 100 bases:

>100_bases
GTTATTGCCTGCCCACTTTTCTGGATGTCGTCAATCTCAACATTCTTTCGAGTTGCAGGTAGGATGGCGACCATTGGTTT
TATTGCGCAGAGGGTTGAGT

Downstream 100 bases:

>100_bases
CACAACTGATTGACCTGTTGGAAGACGTTCGTGCCTGCCGGCTGTGTGAGTCGCATCTGCCGCTGGGGCCGCGGCCGGTG
GTGCAGGCTGGGCAGGGCGC

Product: acyl-CoA thioesterase II

Products: Hydrolyzed acyl-CoA thioesters [C]

Alternate protein names: Acyl-CoA thioesterase II; TEII [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MKASVQELMNLFDLEQLENNLFRGQSEANGQRSVFGGLVAGQALLAASRTVDDARPVHSLHAYFLRPGDFNVPIVYYVDR
IRDGKSFTTRRVDAIQHGRPIFSLAASYQVAEEGVSHQSVMPDVPGPEGLENDEGIRMKLVDRLPEQFRKDFLTDRPVEF
RPVTPKDSISSEPQDPVREVWFRVVDRVDANPMTQRALLAYCSDFGLMGTAMLPHGMNFWQPNVQCASIDHAMWFHNDFR
IDEWLLYRSDSPFSGGSRGLNFGSIYRQDGTLVASVAQEGLMRLHPSDSPTE

Sequences:

>Translated_292_residues
MKASVQELMNLFDLEQLENNLFRGQSEANGQRSVFGGLVAGQALLAASRTVDDARPVHSLHAYFLRPGDFNVPIVYYVDR
IRDGKSFTTRRVDAIQHGRPIFSLAASYQVAEEGVSHQSVMPDVPGPEGLENDEGIRMKLVDRLPEQFRKDFLTDRPVEF
RPVTPKDSISSEPQDPVREVWFRVVDRVDANPMTQRALLAYCSDFGLMGTAMLPHGMNFWQPNVQCASIDHAMWFHNDFR
IDEWLLYRSDSPFSGGSRGLNFGSIYRQDGTLVASVAQEGLMRLHPSDSPTE
>Mature_292_residues
MKASVQELMNLFDLEQLENNLFRGQSEANGQRSVFGGLVAGQALLAASRTVDDARPVHSLHAYFLRPGDFNVPIVYYVDR
IRDGKSFTTRRVDAIQHGRPIFSLAASYQVAEEGVSHQSVMPDVPGPEGLENDEGIRMKLVDRLPEQFRKDFLTDRPVEF
RPVTPKDSISSEPQDPVREVWFRVVDRVDANPMTQRALLAYCSDFGLMGTAMLPHGMNFWQPNVQCASIDHAMWFHNDFR
IDEWLLYRSDSPFSGGSRGLNFGSIYRQDGTLVASVAQEGLMRLHPSDSPTE

Specific function: Can hydrolyze a broad range of acyl-CoA thioesters. Its physiological function is not known [H]

COG id: COG1946

COG function: function code I; Acyl-CoA thioesterase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the C/M/P thioester hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI34577075, Length=294, Percent_Identity=39.7959183673469, Blast_Score=221, Evalue=6e-58,
Organism=Escherichia coli, GI1786657, Length=271, Percent_Identity=47.9704797047971, Blast_Score=270, Evalue=1e-73,
Organism=Caenorhabditis elegans, GI71988741, Length=290, Percent_Identity=37.2413793103448, Blast_Score=193, Evalue=7e-50,
Organism=Caenorhabditis elegans, GI17558508, Length=313, Percent_Identity=36.1022364217252, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI115532456, Length=313, Percent_Identity=35.1437699680511, Blast_Score=161, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17531889, Length=313, Percent_Identity=35.1437699680511, Blast_Score=160, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI17531885, Length=313, Percent_Identity=35.1437699680511, Blast_Score=160, Evalue=7e-40,
Organism=Caenorhabditis elegans, GI71982224, Length=309, Percent_Identity=34.3042071197411, Blast_Score=153, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI212645202, Length=287, Percent_Identity=30.3135888501742, Blast_Score=123, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6322480, Length=303, Percent_Identity=24.0924092409241, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003703 [H]

Pfam domain/function: PF02551 Acyl_CoA_thio [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 32906; Mature: 32906

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKASVQELMNLFDLEQLENNLFRGQSEANGQRSVFGGLVAGQALLAASRTVDDARPVHSL
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
HAYFLRPGDFNVPIVYYVDRIRDGKSFTTRRVDAIQHGRPIFSLAASYQVAEEGVSHQSV
HHHEECCCCCCCCCEEEEEHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCC
MPDVPGPEGLENDEGIRMKLVDRLPEQFRKDFLTDRPVEFRPVTPKDSISSEPQDPVREV
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCHHHHHH
WFRVVDRVDANPMTQRALLAYCSDFGLMGTAMLPHGMNFWQPNVQCASIDHAMWFHNDFR
HHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCEEEECCHHHHHCCCCC
IDEWLLYRSDSPFSGGSRGLNFGSIYRQDGTLVASVAQEGLMRLHPSDSPTE
CCEEEEEECCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHEEECCCCCCCC
>Mature Secondary Structure
MKASVQELMNLFDLEQLENNLFRGQSEANGQRSVFGGLVAGQALLAASRTVDDARPVHSL
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
HAYFLRPGDFNVPIVYYVDRIRDGKSFTTRRVDAIQHGRPIFSLAASYQVAEEGVSHQSV
HHHEECCCCCCCCCEEEEEHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCC
MPDVPGPEGLENDEGIRMKLVDRLPEQFRKDFLTDRPVEFRPVTPKDSISSEPQDPVREV
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCHHHHHH
WFRVVDRVDANPMTQRALLAYCSDFGLMGTAMLPHGMNFWQPNVQCASIDHAMWFHNDFR
HHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCEEEECCHHHHHCCCCC
IDEWLLYRSDSPFSGGSRGLNFGSIYRQDGTLVASVAQEGLMRLHPSDSPTE
CCEEEEEECCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA thioesters [C]

Specific reaction: Hydrolyzes a broad range of acyl-CoA thioesters [C]

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]