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The map label for this gene is yfjB

Identifier: 110833856

GI number: 110833856

Start: 1126876

End: 1127778

Strand: Direct

Name: yfjB

Synonym: ABO_0995

Alternate gene names: 110833856

Gene position: 1126876-1127778 (Clockwise)

Preceding gene: 110833855

Following gene: 110833857

Centisome position: 36.12

GC content: 53.93

Gene sequence:

>903_bases
ATGAGATCCCTTGTGGCGCAAGAGAAATTTCGCAACATCGGTTTGATCGCACGGTCTGAAAGTGAGCAGGCGCTCTACTC
ATTACGCCAGCTCATTCATTTTCTGCATGGCCGTGATTGCACCGTTATCCTCGATAAACACATTATTGGTCATCTTCCGG
AAATGGGATTGCAGGCTGCTAGTGCCTCACAAATGGGGGAAGCCTGCGATCTGGTGATTGTGGTGGGAGGGGACGGTAGT
CTGCTAGGTGCTGCGCGTACCCTGGCTCGCTATAAAGTGCCGGTATTGGGCGTGAATCGGGGCCATCTGGGCTTTCTCAC
CGATATCCTTCCTTCTGAAATTGAATCCCGGGTCGGCCAGGTGCTGGATGGTGAATACAGTACCGAAAAACGGTTCTTGT
TGGATCTGGAAGTGCGCCGGGGTAGGACCGTGGTCGGCGAGGGGAGCGCTCTCAACGATATCGTGCTGCTATCCGGTGAC
AGTGTACACATGATCGATTTTGAGTTGATGATCGACGGACACTTTGTCTACGGGCAGCGCTCCGACGGGCTGATTGTTTC
TACGCCCACCGGTTCCACCGCCTATGCGTTGTCCGGTGGTGGGCCAATCATGCACCCTAAGCTGGATGCCATGGTCTTGG
TTCCCCTAAACCCCCACACCCTGACCAGTCGCCCCTTGGTGGTAGCTGGGGATAGTGAAATCAAAATTCACATCACCACA
GAAAAAGTGCGGCCGTTGGTCAGTTGCGATGGCACAGAGGGGATTCGCTTGCAGGTTGACGATGTCATTGCGATTCGCAA
AAAACCTCACCGCTTACATTTGATTCATCCCCCGGGGCACGATTTCTATCAGGCTTGTCGGTCTAAATTGGGCTGGAGTT
CCCGGCCCGGTGACAACAATTAG

Upstream 100 bases:

>100_bases
TGCTGTTACCCTGAACGAGTACCTGACTCAGGGGTAGTGCTTGCCGGTTGGTGAGGCTGCCCAGTCCGGCTTCCGCAACA
ACCTAAGCAGCACTACCTGA

Downstream 100 bases:

>100_bases
GCCGAGTAATACTGTATAGGCCGTGGGCCGCCCAAATCTATGTAGCGTGTCGCGTACCGTGACCTTTTGAAGAGTTAAAC
CATGAGTTACCAGAGTTTTG

Product: nicotinamide adenine dinucleotide kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MRSLVAQEKFRNIGLIARSESEQALYSLRQLIHFLHGRDCTVILDKHIIGHLPEMGLQAASASQMGEACDLVIVVGGDGS
LLGAARTLARYKVPVLGVNRGHLGFLTDILPSEIESRVGQVLDGEYSTEKRFLLDLEVRRGRTVVGEGSALNDIVLLSGD
SVHMIDFELMIDGHFVYGQRSDGLIVSTPTGSTAYALSGGGPIMHPKLDAMVLVPLNPHTLTSRPLVVAGDSEIKIHITT
EKVRPLVSCDGTEGIRLQVDDVIAIRKKPHRLHLIHPPGHDFYQACRSKLGWSSRPGDNN

Sequences:

>Translated_300_residues
MRSLVAQEKFRNIGLIARSESEQALYSLRQLIHFLHGRDCTVILDKHIIGHLPEMGLQAASASQMGEACDLVIVVGGDGS
LLGAARTLARYKVPVLGVNRGHLGFLTDILPSEIESRVGQVLDGEYSTEKRFLLDLEVRRGRTVVGEGSALNDIVLLSGD
SVHMIDFELMIDGHFVYGQRSDGLIVSTPTGSTAYALSGGGPIMHPKLDAMVLVPLNPHTLTSRPLVVAGDSEIKIHITT
EKVRPLVSCDGTEGIRLQVDDVIAIRKKPHRLHLIHPPGHDFYQACRSKLGWSSRPGDNN
>Mature_300_residues
MRSLVAQEKFRNIGLIARSESEQALYSLRQLIHFLHGRDCTVILDKHIIGHLPEMGLQAASASQMGEACDLVIVVGGDGS
LLGAARTLARYKVPVLGVNRGHLGFLTDILPSEIESRVGQVLDGEYSTEKRFLLDLEVRRGRTVVGEGSALNDIVLLSGD
SVHMIDFELMIDGHFVYGQRSDGLIVSTPTGSTAYALSGGGPIMHPKLDAMVLVPLNPHTLTSRPLVVAGDSEIKIHITT
EKVRPLVSCDGTEGIRLQVDDVIAIRKKPHRLHLIHPPGHDFYQACRSKLGWSSRPGDNN

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family

Homologues:

Organism=Homo sapiens, GI55743112, Length=255, Percent_Identity=31.3725490196078, Blast_Score=104, Evalue=1e-22,
Organism=Escherichia coli, GI1788968, Length=286, Percent_Identity=42.3076923076923, Blast_Score=248, Evalue=4e-67,
Organism=Saccharomyces cerevisiae, GI6322509, Length=242, Percent_Identity=29.7520661157025, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6320794, Length=242, Percent_Identity=28.5123966942149, Blast_Score=119, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6325068, Length=290, Percent_Identity=26.8965517241379, Blast_Score=105, Evalue=6e-24,
Organism=Drosophila melanogaster, GI28573832, Length=201, Percent_Identity=33.3333333333333, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28573830, Length=201, Percent_Identity=33.3333333333333, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28573828, Length=201, Percent_Identity=33.3333333333333, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI161077047, Length=206, Percent_Identity=32.5242718446602, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI28573826, Length=206, Percent_Identity=32.5242718446602, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI20129957, Length=277, Percent_Identity=26.3537906137184, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24653422, Length=277, Percent_Identity=26.3537906137184, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI281363321, Length=277, Percent_Identity=26.3537906137184, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI281363323, Length=279, Percent_Identity=26.5232974910394, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24653424, Length=279, Percent_Identity=26.5232974910394, Blast_Score=82, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPNK_ALCBS (Q0VQV5)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_692715.1
- ProteinModelPortal:   Q0VQV5
- SMR:   Q0VQV5
- STRING:   Q0VQV5
- GeneID:   4211794
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_0995
- NMPDR:   fig|393595.12.peg.1002
- eggNOG:   COG0061
- HOGENOM:   HBG713904
- OMA:   FESFMID
- PhylomeDB:   Q0VQV5
- BioCyc:   ABOR393595:ABO_0995-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00361
- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504
- Gene3D:   G3DSA:2.60.200.30
- Gene3D:   G3DSA:3.40.50.10330
- PANTHER:   PTHR20275

Pfam domain/function: PF01513 NAD_kinase; SSF111331 ATP-NAD_kinase_PpnK-typ

EC number: =2.7.1.23

Molecular weight: Translated: 32683; Mature: 32683

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSLVAQEKFRNIGLIARSESEQALYSLRQLIHFLHGRDCTVILDKHIIGHLPEMGLQAA
CCCHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHCCCCEEEEEECHHHHCCCHHCCHHH
SASQMGEACDLVIVVGGDGSLLGAARTLARYKVPVLGVNRGHLGFLTDILPSEIESRVGQ
CHHHCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHH
VLDGEYSTEKRFLLDLEVRRGRTVVGEGSALNDIVLLSGDSVHMIDFELMIDGHFVYGQR
HHCCCCCCCCEEEEEEEECCCCEEEECCCCCCEEEEEECCCEEEEEEEEEEECEEEECCC
SDGLIVSTPTGSTAYALSGGGPIMHPKLDAMVLVPLNPHTLTSRPLVVAGDSEIKIHITT
CCCEEEECCCCCEEEEEECCCCEECCCCCEEEEEECCCCCCCCCCEEEECCCEEEEEEEH
EKVRPLVSCDGTEGIRLQVDDVIAIRKKPHRLHLIHPPGHDFYQACRSKLGWSSRPGDNN
HHCCEEEECCCCCCEEEEECCEEEECCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MRSLVAQEKFRNIGLIARSESEQALYSLRQLIHFLHGRDCTVILDKHIIGHLPEMGLQAA
CCCHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHCCCCEEEEEECHHHHCCCHHCCHHH
SASQMGEACDLVIVVGGDGSLLGAARTLARYKVPVLGVNRGHLGFLTDILPSEIESRVGQ
CHHHCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHH
VLDGEYSTEKRFLLDLEVRRGRTVVGEGSALNDIVLLSGDSVHMIDFELMIDGHFVYGQR
HHCCCCCCCCEEEEEEEECCCCEEEECCCCCCEEEEEECCCEEEEEEEEEEECEEEECCC
SDGLIVSTPTGSTAYALSGGGPIMHPKLDAMVLVPLNPHTLTSRPLVVAGDSEIKIHITT
CCCEEEECCCCCEEEEEECCCCEECCCCCEEEEEECCCCCCCCCCEEEECCCEEEEEEEH
EKVRPLVSCDGTEGIRLQVDDVIAIRKKPHRLHLIHPPGHDFYQACRSKLGWSSRPGDNN
HHCCEEEECCCCCCEEEEECCEEEECCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA