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The map label for this gene is cmoA

Identifier: 110833834

GI number: 110833834

Start: 1098965

End: 1099714

Strand: Direct

Name: cmoA

Synonym: ABO_0973

Alternate gene names: 110833834

Gene position: 1098965-1099714 (Clockwise)

Preceding gene: 110833833

Following gene: 110833835

Centisome position: 35.22

GC content: 54.8

Gene sequence:

>750_bases
ATGCATACAGGGGCCTTTATGTCTGATCAACAAGATCGTATTTACGCCACGTCACACTCGCAGGTGGGGCGTTTTTCCTT
CGACGACACAGTGGTGCGGGTTTTTCCGGACATGATTCGCCGCTCGGTGCCGGGCTATCCGACTATTATCGACATGATTG
GGGTGCTGGCGGCCCGGTACGCGCAGCCGGATACTTGCCTGTATGACCTGGGGTGTTCCCTAGGGGCCGCCGCCACTGCC
ATGGCGACCCTGACCGGGGACACCGGTAATCCTATTGTTGCGGTGGATAATTCCCGGGCCATGATTGAGCAGGCCGAGAA
CTTGCTCTCTCAAGCTGGTCAGGCACATCGGGTGACACTGCAAGAAGGCGATGTGGCAGAGATGGCGTTCAATTCTTGTT
CCATGGCGGTGCTCAATTTTACCTTGCAGTTCATCGCCCTGGAAAAACGTGATGCCCTGATTCGACGCCTGGCCGATGCC
ACGGTGCCTGGTGGCATCCTGGTGCTATCGGAGAAAATCCGTTTCGCCAATGACGCTGAGAATGCCTTGCAGACCGAATT
GCACCATGCGTTCAAACGCAATAATGGCTATTCCGATCTGGAAATCAGCCAGAAGCGTAATGCGCTGGAAAATGTACTGA
TTCCGGAAACCCTGGCGGCCCACGAGACGCGACTGAAAAAAGCGGGCTACCGCCAGATTCATGTCTGGTTCCGCTGTTTT
AACTTTGTTTCATTACTGGCTGTGCGTTAA

Upstream 100 bases:

>100_bases
TTGCCAGGATAGCCCGACGGTAGGGGCGTAATGTGCCCGTTAGCCTGGACGAATAAGCGTTTCTTCCGGGCTCAGCTCCT
CGCTATAATCGGCGCCGCAG

Downstream 100 bases:

>100_bases
TGCTTACTGATTACCTGCAGGCCTGCGAACGTGGGCTTGAGCCCCTGTTTTCTCCGCAAATTTTGTCTGCCGTTATGGCG
CTGTCGCGTCAGCGCCTGGT

Product: methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MHTGAFMSDQQDRIYATSHSQVGRFSFDDTVVRVFPDMIRRSVPGYPTIIDMIGVLAARYAQPDTCLYDLGCSLGAAATA
MATLTGDTGNPIVAVDNSRAMIEQAENLLSQAGQAHRVTLQEGDVAEMAFNSCSMAVLNFTLQFIALEKRDALIRRLADA
TVPGGILVLSEKIRFANDAENALQTELHHAFKRNNGYSDLEISQKRNALENVLIPETLAAHETRLKKAGYRQIHVWFRCF
NFVSLLAVR

Sequences:

>Translated_249_residues
MHTGAFMSDQQDRIYATSHSQVGRFSFDDTVVRVFPDMIRRSVPGYPTIIDMIGVLAARYAQPDTCLYDLGCSLGAAATA
MATLTGDTGNPIVAVDNSRAMIEQAENLLSQAGQAHRVTLQEGDVAEMAFNSCSMAVLNFTLQFIALEKRDALIRRLADA
TVPGGILVLSEKIRFANDAENALQTELHHAFKRNNGYSDLEISQKRNALENVLIPETLAAHETRLKKAGYRQIHVWFRCF
NFVSLLAVR
>Mature_249_residues
MHTGAFMSDQQDRIYATSHSQVGRFSFDDTVVRVFPDMIRRSVPGYPTIIDMIGVLAARYAQPDTCLYDLGCSLGAAATA
MATLTGDTGNPIVAVDNSRAMIEQAENLLSQAGQAHRVTLQEGDVAEMAFNSCSMAVLNFTLQFIALEKRDALIRRLADA
TVPGGILVLSEKIRFANDAENALQTELHHAFKRNNGYSDLEISQKRNALENVLIPETLAAHETRLKKAGYRQIHVWFRCF
NFVSLLAVR

Specific function: Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U)

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. CmoA family

Homologues:

Organism=Escherichia coli, GI1788177, Length=240, Percent_Identity=45.8333333333333, Blast_Score=226, Evalue=7e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CMOA_ALCBS (Q0VQX7)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_692693.1
- ProteinModelPortal:   Q0VQX7
- SMR:   Q0VQX7
- STRING:   Q0VQX7
- GeneID:   4212721
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_0973
- NMPDR:   fig|393595.12.peg.979
- eggNOG:   COG0500
- HOGENOM:   HBG296860
- OMA:   YSELEVS
- PhylomeDB:   Q0VQX7
- BioCyc:   ABOR393595:ABO_0973-MONOMER
- HAMAP:   MF_01589
- InterPro:   IPR013216
- InterPro:   IPR005271
- PIRSF:   PIRSF006325
- TIGRFAMs:   TIGR00740

Pfam domain/function: PF08241 Methyltransf_11

EC number: NA

Molecular weight: Translated: 27538; Mature: 27538

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: BINDING 46-46 BINDING 96-96 BINDING 139-139 BINDING 206-206

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTGAFMSDQQDRIYATSHSQVGRFSFDDTVVRVFPDMIRRSVPGYPTIIDMIGVLAARY
CCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHC
AQPDTCLYDLGCSLGAAATAMATLTGDTGNPIVAVDNSRAMIEQAENLLSQAGQAHRVTL
CCCCCHHHHHCCCHHHHHHHHHEEECCCCCCEEEECCCHHHHHHHHHHHHHCCCCEEEEE
QEGDVAEMAFNSCSMAVLNFTLQFIALEKRDALIRRLADATVPGGILVLSEKIRFANDAE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHCCCCHH
NALQTELHHAFKRNNGYSDLEISQKRNALENVLIPETLAAHETRLKKAGYRQIHVWFRCF
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHH
NFVSLLAVR
HHHHHHHCC
>Mature Secondary Structure
MHTGAFMSDQQDRIYATSHSQVGRFSFDDTVVRVFPDMIRRSVPGYPTIIDMIGVLAARY
CCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHC
AQPDTCLYDLGCSLGAAATAMATLTGDTGNPIVAVDNSRAMIEQAENLLSQAGQAHRVTL
CCCCCHHHHHCCCHHHHHHHHHEEECCCCCCEEEECCCHHHHHHHHHHHHHCCCCEEEEE
QEGDVAEMAFNSCSMAVLNFTLQFIALEKRDALIRRLADATVPGGILVLSEKIRFANDAE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHCCCCHH
NALQTELHHAFKRNNGYSDLEISQKRNALENVLIPETLAAHETRLKKAGYRQIHVWFRCF
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHH
NFVSLLAVR
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA