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The map label for this gene is ccmE [H]

Identifier: 110833735

GI number: 110833735

Start: 969231

End: 969713

Strand: Direct

Name: ccmE [H]

Synonym: ABO_0874

Alternate gene names: 110833735

Gene position: 969231-969713 (Clockwise)

Preceding gene: 110833734

Following gene: 110833736

Centisome position: 31.06

GC content: 56.11

Gene sequence:

>483_bases
ATGAATCCGGTACGTAAGCAGCGTCTTTTGGTGGTACTCGCCGTTTTGGTTGGCTTGGGGGTTGCCTGTGCCCTGATGTT
TTATGCGCTGCGCCAAAACATCAACCTGTTCTATACCCCTCAGCAAATTGCTGCAGGGGAGGCTCCGCTGGATGCCCAGA
TGCGCGTGGGCGGTTTAGTGGAACCGGGTACCGTTATCCGTAACCCGGAAACATTGGACGTGACCTTTGTGCTCACTGAT
GGCAAGGGACGCTTCACCGTGCACTATCAAGGGATACTGCCGGACCTGTTCCGCGAAGGGCAGGGTATTGTTGCCAACGG
CACGCTGATCAGCCAGACCCGCTTTGAAGCCGAGGAAGTTCTGGCCAAGCATGATGAAACTTATATGCCACCGGAGGTAC
AGGATGCGCTGGAAAAAGCGGGTCATCCGGGTGCCCAAAAACCAGAAGGCAAGGCTCAGCCGCAAAGCGGGCCAGCTTAC
TAG

Upstream 100 bases:

>100_bases
ACGCTGGCGCGGCAATGGCGTCTTGAGGACATTGCTAAGCAACAAGCTCAAGACACGGCGAGTCGACAGCAATCCAGTAA
GCAAACGCCTGAGGTAAACG

Downstream 100 bases:

>100_bases
CGGGTAGTCGAGAAGCCGGCTGGCGGCAGCCGGTAAATTTCTCTTGCTCAACGCCTGGTTTCGGCCCTACATTCGCCTTT
ATCGGACCCCGTTCGGGGGG

Product: cytochrome c-type biogenesis protein CcmE

Products: NA

Alternate protein names: Cytochrome c maturation protein E; Heme chaperone CcmE [H]

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MNPVRKQRLLVVLAVLVGLGVACALMFYALRQNINLFYTPQQIAAGEAPLDAQMRVGGLVEPGTVIRNPETLDVTFVLTD
GKGRFTVHYQGILPDLFREGQGIVANGTLISQTRFEAEEVLAKHDETYMPPEVQDALEKAGHPGAQKPEGKAQPQSGPAY

Sequences:

>Translated_160_residues
MNPVRKQRLLVVLAVLVGLGVACALMFYALRQNINLFYTPQQIAAGEAPLDAQMRVGGLVEPGTVIRNPETLDVTFVLTD
GKGRFTVHYQGILPDLFREGQGIVANGTLISQTRFEAEEVLAKHDETYMPPEVQDALEKAGHPGAQKPEGKAQPQSGPAY
>Mature_160_residues
MNPVRKQRLLVVLAVLVGLGVACALMFYALRQNINLFYTPQQIAAGEAPLDAQMRVGGLVEPGTVIRNPETLDVTFVLTD
GKGRFTVHYQGILPDLFREGQGIVANGTLISQTRFEAEEVLAKHDETYMPPEVQDALEKAGHPGAQKPEGKAQPQSGPAY

Specific function: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH [H]

COG id: COG2332

COG function: function code O; Cytochrome c-type biogenesis protein CcmE

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmE/CycJ family [H]

Homologues:

Organism=Escherichia coli, GI1788525, Length=148, Percent_Identity=51.3513513513513, Blast_Score=146, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004329
- InterPro:   IPR012340 [H]

Pfam domain/function: PF03100 CcmE [H]

EC number: NA

Molecular weight: Translated: 17383; Mature: 17383

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPVRKQRLLVVLAVLVGLGVACALMFYALRQNINLFYTPQQIAAGEAPLDAQMRVGGLV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHCCCCCCCCHHHCCCCC
EPGTVIRNPETLDVTFVLTDGKGRFTVHYQGILPDLFREGQGIVANGTLISQTRFEAEEV
CCCCEECCCCEEEEEEEEECCCCEEEEEECCCCHHHHHCCCCEEECCEEECHHHHHHHHH
LAKHDETYMPPEVQDALEKAGHPGAQKPEGKAQPQSGPAY
HHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNPVRKQRLLVVLAVLVGLGVACALMFYALRQNINLFYTPQQIAAGEAPLDAQMRVGGLV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHCCCCCCCCHHHCCCCC
EPGTVIRNPETLDVTFVLTDGKGRFTVHYQGILPDLFREGQGIVANGTLISQTRFEAEEV
CCCCEECCCCEEEEEEEEECCCCEEEEEECCCCHHHHHCCCCEEECCEEECHHHHHHHHH
LAKHDETYMPPEVQDALEKAGHPGAQKPEGKAQPQSGPAY
HHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA