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The map label for this gene is tadA [H]

Identifier: 110833682

GI number: 110833682

Start: 914846

End: 915304

Strand: Direct

Name: tadA [H]

Synonym: ABO_0821

Alternate gene names: 110833682

Gene position: 914846-915304 (Clockwise)

Preceding gene: 110833679

Following gene: 110833687

Centisome position: 29.32

GC content: 55.77

Gene sequence:

>459_bases
GTGGACGATCAAGACTGGATGCAACAGGCTCTAATGCTGGCTCGTCAGGCGGCAGATCAGGGAGAGGTGCCTGTGGGGGC
GCTGGTGGTTCGTGGAGGGCAGTTGTTGGGGCAGGGCTATAACCAGCCGATTACCGCCAATGATCCCAGTGCTCATGCGG
AGATCATTGCCATGCGTAGTGCGTCCCTTGCAGAAAAGAATTACCGTCTTAGCGGTTGTACGCTCTATGTCACCCTAGAG
CCCTGCACCATGTGTTTTGGTGCCATGGTTCATGCCCGCATCGGCAGGCTTGTATATGGCGCTAGTGAGCCACGTGCGGG
GGTATGCGAAAGCCAGTTGCAGCTGCCATCGGTGGATTTCTACAATCATCGGGTGGAAGTGGAAAAAGGCGTTTTGGCAG
AGGAAAGCGCTATGCTGCTCAAACGTTTCTTTGCGGATCGTCGAAAGAGGCCGCGTTAG

Upstream 100 bases:

>100_bases
GGCTGCCCTTGCCTCATTCTGTGCGCAGGAGGCTTGCGGTACACTTGGTGTGTTGTGCTTGCTGGGCGAGTTAGTCTGGG
GCGTGAATTAAGGAGAGTAG

Downstream 100 bases:

>100_bases
AACGTTGCTGGGAAAACAGACCTTTCGTGGCGTCAGCAGAAACGATCTGCTCAGGTTGTGTTGCTTGCTGTGAGAGTGCT
GAGATCACAGAACGAAAAAA

Product: cytidine/deoxycytidylate deaminase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MDDQDWMQQALMLARQAADQGEVPVGALVVRGGQLLGQGYNQPITANDPSAHAEIIAMRSASLAEKNYRLSGCTLYVTLE
PCTMCFGAMVHARIGRLVYGASEPRAGVCESQLQLPSVDFYNHRVEVEKGVLAEESAMLLKRFFADRRKRPR

Sequences:

>Translated_152_residues
MDDQDWMQQALMLARQAADQGEVPVGALVVRGGQLLGQGYNQPITANDPSAHAEIIAMRSASLAEKNYRLSGCTLYVTLE
PCTMCFGAMVHARIGRLVYGASEPRAGVCESQLQLPSVDFYNHRVEVEKGVLAEESAMLLKRFFADRRKRPR
>Mature_152_residues
MDDQDWMQQALMLARQAADQGEVPVGALVVRGGQLLGQGYNQPITANDPSAHAEIIAMRSASLAEKNYRLSGCTLYVTLE
PCTMCFGAMVHARIGRLVYGASEPRAGVCESQLQLPSVDFYNHRVEVEKGVLAEESAMLLKRFFADRRKRPR

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=151, Percent_Identity=32.4503311258278, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI145693172, Length=144, Percent_Identity=51.3888888888889, Blast_Score=160, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17541138, Length=152, Percent_Identity=36.1842105263158, Blast_Score=89, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17554608, Length=103, Percent_Identity=36.8932038834951, Blast_Score=88, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17555996, Length=84, Percent_Identity=38.0952380952381, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322425, Length=168, Percent_Identity=30.952380952381, Blast_Score=66, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21355527, Length=145, Percent_Identity=33.1034482758621, Blast_Score=83, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 16814; Mature: 16814

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDQDWMQQALMLARQAADQGEVPVGALVVRGGQLLGQGYNQPITANDPSAHAEIIAMRS
CCCHHHHHHHHHHHHHHCCCCCCCCHHEEEECCHHHCCCCCCCCCCCCCCCHHHHHHHHH
ASLAEKNYRLSGCTLYVTLEPCTMCFGAMVHARIGRLVYGASEPRAGVCESQLQLPSVDF
HHHHHCCCEECCEEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCC
YNHRVEVEKGVLAEESAMLLKRFFADRRKRPR
CCCEEECCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDDQDWMQQALMLARQAADQGEVPVGALVVRGGQLLGQGYNQPITANDPSAHAEIIAMRS
CCCHHHHHHHHHHHHHHCCCCCCCCHHEEEECCHHHCCCCCCCCCCCCCCCHHHHHHHHH
ASLAEKNYRLSGCTLYVTLEPCTMCFGAMVHARIGRLVYGASEPRAGVCESQLQLPSVDF
HHHHHCCCEECCEEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCC
YNHRVEVEKGVLAEESAMLLKRFFADRRKRPR
CCCEEECCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]