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The map label for this gene is mlrA [H]

Identifier: 110833626

GI number: 110833626

Start: 858473

End: 859384

Strand: Direct

Name: mlrA [H]

Synonym: ABO_0765

Alternate gene names: 110833626

Gene position: 858473-859384 (Clockwise)

Preceding gene: 110833625

Following gene: 110833627

Centisome position: 27.51

GC content: 61.29

Gene sequence:

>912_bases
ATGAGCGAGTCTACAAGCAGGGTTCAAGTTGCGGACCGACAAGCCGGTAGCATCAGCATTCAGCACGTGAGCATGCACTG
CGGTATCCCCGCGGTGACTTTGCGTGCCTGGGAGCGTCGTTATGGTTTGTTGACGCCCGCACGCACGGATAAAGGGCATC
GGCGTTATAGCGAAGTGGATATCGCTTGTATCGAGCAGATTCAGCATTGGCTGGAGCGAGGGGTGCCGATCAGTCAGGTG
GCGGGGCTACTGGCTGATTCAGCAGCGGCTAACGGGGCGGTGTGGGAACAGGGTGCCGAACAGCAAGGGCCTTGGCGCGG
GGCAGTAACAGACGCGATCTGCGCGCTGGAGTCGCTCAACACCCGCCGTCTGGAACAGTTGCTCAATGGGCTGCTGAATG
ATTATAGCCATGCTCTGGTACTGGATCACTTTTGTGATCCCGTGCGGGCACGTTTGGCTGACACTTCAGCCCTGGGTGGA
TGGCTCACCCTGTTTGACGGTGTGCTGCAGGCCAAGTGGTCGTCGCGGGCATTATCGCTGGCGCCACGGGGTGGGGAGGC
CGGCTGGTTGCTGGTGCCGGTGGGGAGAGCCTTGCCGGCACTGGAACTGGCGATGGTATTGAACCGCCCGCTCTGGTGTC
TGGGGGCTCCTTTGGTGACGGTAGAACTGCGCAGTGTACTCAAAAGCCTGGCGCAACGGGCCGGTGGTGTGCTCTGGGTG
GTGGATCGCTGGCCAACGGCGGCCCAGCGTCAGCAAATCGGTATCGCTTCTGGTTGTGGCCTCAGTGAGGCGTGCTGGGG
GCTGGATCTATCGCAAATGACACTGCCGCAAGAGGTAGCCCAGCTTGGCGGGCGTCGGCAGGGGCTGGCGAGCGAACTGG
ATCGACTTCAACAATCCTGGAGTACGCCATGA

Upstream 100 bases:

>100_bases
CCCTGTTGCGTGGTGCCCTGCGTAAAACCGATCAGCCTTACTTGGCCCAGCAGCGCTATCTTTCCCCGTACCCGGACCCG
CTAGGCCTGAGAAATCGGGT

Downstream 100 bases:

>100_bases
ATCTGGTCTGGTACCGCAACGACCTGCGTGTCGCGGCACACTCGCCTCTGCACGCTGCGTTGACAGAGTCATCGATAAGC
GCGGGTGAGACGAGGCCACA

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: MerR-like regulator A [H]

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MSESTSRVQVADRQAGSISIQHVSMHCGIPAVTLRAWERRYGLLTPARTDKGHRRYSEVDIACIEQIQHWLERGVPISQV
AGLLADSAAANGAVWEQGAEQQGPWRGAVTDAICALESLNTRRLEQLLNGLLNDYSHALVLDHFCDPVRARLADTSALGG
WLTLFDGVLQAKWSSRALSLAPRGGEAGWLLVPVGRALPALELAMVLNRPLWCLGAPLVTVELRSVLKSLAQRAGGVLWV
VDRWPTAAQRQQIGIASGCGLSEACWGLDLSQMTLPQEVAQLGGRRQGLASELDRLQQSWSTP

Sequences:

>Translated_303_residues
MSESTSRVQVADRQAGSISIQHVSMHCGIPAVTLRAWERRYGLLTPARTDKGHRRYSEVDIACIEQIQHWLERGVPISQV
AGLLADSAAANGAVWEQGAEQQGPWRGAVTDAICALESLNTRRLEQLLNGLLNDYSHALVLDHFCDPVRARLADTSALGG
WLTLFDGVLQAKWSSRALSLAPRGGEAGWLLVPVGRALPALELAMVLNRPLWCLGAPLVTVELRSVLKSLAQRAGGVLWV
VDRWPTAAQRQQIGIASGCGLSEACWGLDLSQMTLPQEVAQLGGRRQGLASELDRLQQSWSTP
>Mature_302_residues
SESTSRVQVADRQAGSISIQHVSMHCGIPAVTLRAWERRYGLLTPARTDKGHRRYSEVDIACIEQIQHWLERGVPISQVA
GLLADSAAANGAVWEQGAEQQGPWRGAVTDAICALESLNTRRLEQLLNGLLNDYSHALVLDHFCDPVRARLADTSALGGW
LTLFDGVLQAKWSSRALSLAPRGGEAGWLLVPVGRALPALELAMVLNRPLWCLGAPLVTVELRSVLKSLAQRAGGVLWVV
DRWPTAAQRQQIGIASGCGLSEACWGLDLSQMTLPQEVAQLGGRRQGLASELDRLQQSWSTP

Specific function: Transcriptional activator of the csg genes required for production of the curli (AgF) [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788448, Length=152, Percent_Identity=35.5263157894737, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1787409, Length=176, Percent_Identity=32.3863636363636, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551 [H]

Pfam domain/function: PF00376 MerR [H]

EC number: NA

Molecular weight: Translated: 32903; Mature: 32772

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESTSRVQVADRQAGSISIQHVSMHCGIPAVTLRAWERRYGLLTPARTDKGHRRYSEVD
CCCCCCCEEECCCCCCCEEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
IACIEQIQHWLERGVPISQVAGLLADSAAANGAVWEQGAEQQGPWRGAVTDAICALESLN
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHCC
TRRLEQLLNGLLNDYSHALVLDHFCDPVRARLADTSALGGWLTLFDGVLQAKWSSRALSL
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
APRGGEAGWLLVPVGRALPALELAMVLNRPLWCLGAPLVTVELRSVLKSLAQRAGGVLWV
CCCCCCCCEEEEECCCHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHCCCEEEE
VDRWPTAAQRQQIGIASGCGLSEACWGLDLSQMTLPQEVAQLGGRRQGLASELDRLQQSW
EECCCCHHHHHHCCCCCCCCCHHHHHCCCHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHC
STP
CCC
>Mature Secondary Structure 
SESTSRVQVADRQAGSISIQHVSMHCGIPAVTLRAWERRYGLLTPARTDKGHRRYSEVD
CCCCCCEEECCCCCCCEEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
IACIEQIQHWLERGVPISQVAGLLADSAAANGAVWEQGAEQQGPWRGAVTDAICALESLN
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHCC
TRRLEQLLNGLLNDYSHALVLDHFCDPVRARLADTSALGGWLTLFDGVLQAKWSSRALSL
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
APRGGEAGWLLVPVGRALPALELAMVLNRPLWCLGAPLVTVELRSVLKSLAQRAGGVLWV
CCCCCCCCEEEEECCCHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHCCCEEEE
VDRWPTAAQRQQIGIASGCGLSEACWGLDLSQMTLPQEVAQLGGRRQGLASELDRLQQSW
EECCCCHHHHHHCCCCCCCCCHHHHHCCCHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHC
STP
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11489123; 9278503 [H]