Click here to switch to the map view.

The map label for this gene is rimK

Identifier: 110833589

GI number: 110833589

Start: 818062

End: 818970

Strand: Direct

Name: rimK

Synonym: ABO_0728

Alternate gene names: 110833589

Gene position: 818062-818970 (Clockwise)

Preceding gene: 110833588

Following gene: 110833590

Centisome position: 26.22

GC content: 56.55

Gene sequence:

>909_bases
ATGAAAATTGCGATTCTTTCCCGAAACAAGCGTTTGTACTCTACGCGTCGCCTGGTCGAAGCCGGCGAAGCAGCGGGCCA
TGAAATGCACGTAATTGACACTCTGCGTTGCTATATGAGCATGGTGGCCCACAAGCCGGAGATTCACTACAAAGGTGAAG
TGCTGGAAGGCTTTGATGCGGTGATCCCCCGTATTGGCGCCTCGATTACCCAGTACGGCACGGCGGTGGTGCGCCAGTTT
GAAATGATGGGCGTGTTTCCGGTGAATGAATCGGTGGCGATCTCCCGTTCCCGGGACAAACTTCGCTCCTTGCAGCTATT
GTCCCGTAAAGGGGTTGGCCTGCCGATTACCGGTTTTGCTCATTCTCCGGATGACATTCCTGATCTGATCAACATGGTTC
GCGGTGCGCCGCTGGTGATCAAAATGTTGGAAGGCACCCAGGGAATCGGTGTGGTGCTGGCGGAAACACGCAAGGCGGCA
GAGTCGGTGATCGAAGCCTTTATGGGTTTGAACGTCTCGGTGATGGTGCAGGAGTACATCAAGGAGGCCGGCGGTGCGGA
TATCCGCTGTTTTGTGGTGGGCGGCAAGGTGATTGCGGCCATGAAGCGCCAGGCCGCCCCGGGTGAATTTCGCTCCAACC
TGCACCGCGGTGGCAGTGCTAGCCTGATCCGTATTACCCCGGAAGAGCGCGCCACTGCGGTGCGTGCTGCGCGCATCATG
GGCCTCAACGTGGCCGGTGTGGATATCCTGCGTTCACACCATGGCCCTGTGGTTATGGAAGTGAATTCCTCGCCGGGCCT
CGAAGGCATCGAAACAGCCACCAATAAGGATGTGGCCGGTTTGCTGATCAAATTTATCGAAAAGGATGCGCGGCCTTATA
GAACCCAGACAAAAGGATCCAAAGGCTGA

Upstream 100 bases:

>100_bases
AAAATATGAAATTCCGCATGCTGCTGGGACGAACCGCCATGGATTTGATAACTGTGGACCCGACAGCCTCATTCCTACTG
GGCGGCACAAAAGAGCAACC

Downstream 100 bases:

>100_bases
CGGAGGTCACCGTAGGAGCCCCTTGAGGGACGAAATGGGTAGGCGCCATTGGCCTCTTAAGGGCTCCTGCAGGGAGATCT
TTAGCACAACGGTTTTTCTC

Product: ribosomal protein S6 modification protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MKIAILSRNKRLYSTRRLVEAGEAAGHEMHVIDTLRCYMSMVAHKPEIHYKGEVLEGFDAVIPRIGASITQYGTAVVRQF
EMMGVFPVNESVAISRSRDKLRSLQLLSRKGVGLPITGFAHSPDDIPDLINMVRGAPLVIKMLEGTQGIGVVLAETRKAA
ESVIEAFMGLNVSVMVQEYIKEAGGADIRCFVVGGKVIAAMKRQAAPGEFRSNLHRGGSASLIRITPEERATAVRAARIM
GLNVAGVDILRSHHGPVVMEVNSSPGLEGIETATNKDVAGLLIKFIEKDARPYRTQTKGSKG

Sequences:

>Translated_302_residues
MKIAILSRNKRLYSTRRLVEAGEAAGHEMHVIDTLRCYMSMVAHKPEIHYKGEVLEGFDAVIPRIGASITQYGTAVVRQF
EMMGVFPVNESVAISRSRDKLRSLQLLSRKGVGLPITGFAHSPDDIPDLINMVRGAPLVIKMLEGTQGIGVVLAETRKAA
ESVIEAFMGLNVSVMVQEYIKEAGGADIRCFVVGGKVIAAMKRQAAPGEFRSNLHRGGSASLIRITPEERATAVRAARIM
GLNVAGVDILRSHHGPVVMEVNSSPGLEGIETATNKDVAGLLIKFIEKDARPYRTQTKGSKG
>Mature_302_residues
MKIAILSRNKRLYSTRRLVEAGEAAGHEMHVIDTLRCYMSMVAHKPEIHYKGEVLEGFDAVIPRIGASITQYGTAVVRQF
EMMGVFPVNESVAISRSRDKLRSLQLLSRKGVGLPITGFAHSPDDIPDLINMVRGAPLVIKMLEGTQGIGVVLAETRKAA
ESVIEAFMGLNVSVMVQEYIKEAGGADIRCFVVGGKVIAAMKRQAAPGEFRSNLHRGGSASLIRITPEERATAVRAARIM
GLNVAGVDILRSHHGPVVMEVNSSPGLEGIETATNKDVAGLLIKFIEKDARPYRTQTKGSKG

Specific function: Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6

COG id: COG0189

COG function: function code HJ; Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI164663810, Length=232, Percent_Identity=29.7413793103448, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI134254462, Length=241, Percent_Identity=28.2157676348548, Blast_Score=81, Evalue=9e-16,
Organism=Escherichia coli, GI1787076, Length=290, Percent_Identity=65.1724137931034, Blast_Score=393, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RIMK_ALCBS (Q0VRM2)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_692448.1
- STRING:   Q0VRM2
- GeneID:   4212046
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_0728
- NMPDR:   fig|393595.12.peg.731
- eggNOG:   COG0189
- HOGENOM:   HBG679591
- OMA:   CREPRLY
- PhylomeDB:   Q0VRM2
- BioCyc:   ABOR393595:ABO_0728-MONOMER
- GO:   GO:0006412
- HAMAP:   MF_01552
- InterPro:   IPR011761
- InterPro:   IPR013651
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR004666
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- TIGRFAMs:   TIGR00768

Pfam domain/function: PF08443 RimK

EC number: NA

Molecular weight: Translated: 32714; Mature: 32714

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: PS50975 ATP_GRASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAILSRNKRLYSTRRLVEAGEAAGHEMHVIDTLRCYMSMVAHKPEIHYKGEVLEGFDA
CEEEEEECCCHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHCCCCCEECCHHHHHHHH
VIPRIGASITQYGTAVVRQFEMMGVFPVNESVAISRSRDKLRSLQLLSRKGVGLPITGFA
HHHHHCCHHHHHHHHHHHHHHHHEEEECCCCEEECCCHHHHHHHHHHHHCCCCCEEECCC
HSPDDIPDLINMVRGAPLVIKMLEGTQGIGVVLAETRKAAESVIEAFMGLNVSVMVQEYI
CCCCCHHHHHHHHCCCCEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHH
KEAGGADIRCFVVGGKVIAAMKRQAAPGEFRSNLHRGGSASLIRITPEERATAVRAARIM
HHCCCCCEEEEEECCHHHHHHHHCCCCHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHH
GLNVAGVDILRSHHGPVVMEVNSSPGLEGIETATNKDVAGLLIKFIEKDARPYRTQTKGS
CCCCHHHHHHHCCCCCEEEEECCCCCCCCHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCC
KG
CC
>Mature Secondary Structure
MKIAILSRNKRLYSTRRLVEAGEAAGHEMHVIDTLRCYMSMVAHKPEIHYKGEVLEGFDA
CEEEEEECCCHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHCCCCCEECCHHHHHHHH
VIPRIGASITQYGTAVVRQFEMMGVFPVNESVAISRSRDKLRSLQLLSRKGVGLPITGFA
HHHHHCCHHHHHHHHHHHHHHHHEEEECCCCEEECCCHHHHHHHHHHHHCCCCCEEECCC
HSPDDIPDLINMVRGAPLVIKMLEGTQGIGVVLAETRKAAESVIEAFMGLNVSVMVQEYI
CCCCCHHHHHHHHCCCCEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHH
KEAGGADIRCFVVGGKVIAAMKRQAAPGEFRSNLHRGGSASLIRITPEERATAVRAARIM
HHCCCCCEEEEEECCHHHHHHHHCCCCHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHH
GLNVAGVDILRSHHGPVVMEVNSSPGLEGIETATNKDVAGLLIKFIEKDARPYRTQTKGS
CCCCHHHHHHHCCCCCEEEEECCCCCCCCHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCC
KG
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Glu; Ribosomal protein S6 [C]

Specific reaction: Catalyzes the addition of glutamic acids to the carboxyl end of ribosomal protein S6 [C]

General reaction: Ligases; Forming Carbon-Nitrogen Bonds; Acid-D-Amino-Acid Ligases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA