| Definition | Alcanivorax borkumensis SK2 chromosome, complete genome. |
|---|---|
| Accession | NC_008260 |
| Length | 3,120,143 |
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The map label for this gene is ftsI [H]
Identifier: 110833453
GI number: 110833453
Start: 647862
End: 649583
Strand: Direct
Name: ftsI [H]
Synonym: ABO_0592
Alternate gene names: 110833453
Gene position: 647862-649583 (Clockwise)
Preceding gene: 110833452
Following gene: 110833454
Centisome position: 20.76
GC content: 57.55
Gene sequence:
>1722_bases ATGAAGAAACAGGCCCGCAAGATACGGCAACCGAATCACCTGATGCGCTGGCGCTTTGTGCTGGGCTTCTGGTCGGTGTG TGCCTGCCTGTTGTTAATTCGAGCGGTGGATCTTCAGGTTATTCAGCATGATTTTTTGGCCCACCAAGGGGACATCCGCA ACCTGCGGGTGGAGCCGCTGGCGGCTCATCGGGGTGTAATTCGTGATCGTGCGGGTAAGCCATTGGCGGTGAGTACACCG GTGGTGACGCTCTGGGTGAATCCCCGCGAAGCGATGGAGCACCAGGATCAGTGGGGGCGTTTGGCCGGTAATTCGGTGAT TGATCAGAAAGCGTTTGCCCGCAAGGTTCGCCGCCATAAGTCCCGTGAATTTATCTATTTGGAGCGGGGGTTAGCACCGG AAACGGCCAAGACAGTGTTGAGTTTAAATGTGCCCGGTGTCTATGCATTGACAGAATACCGTCGCTATTACCCGGCCGGT GAAGTGGCAAGCCATGTGGTGGGCTTCACCAATATCGATGATCAAGGGCAAGAAGGTATTGAGCTGGCTCTTGAAGATCA TTTGTCCGGGCATTCCGGTCGTAAGAAGGTGGTGCGGGATCTGTTGGGCCGGGTGATTCAGGATATCGAAGTGCTGGAAC CGGCGGAACCGGGTGAAGATGTCACGCTCAGCATCGACCTTCGCCTGCAGTATCTGGCCTACCGAGAACTGCTCGGAGCG GTACAAAAATTTAATGCGAAAGGGGGCAGTGCGGTTGTGTTGGATGTGCGCACCGGCGAAGTATTAGCCATGGTGAATCA GCCAGCCTACAACCCCAATAATCGTGGCAACCTGGATACCGGGGCGCTGCGTAATCGCGCTGTGACTGACCTGTTCGAAC CAGGCTCCACCATGAAGCCCTTTACTGTGGCGGCGGCGTTGGAAATGGGCATGGTCACGCCGTCCACTACCATTAATACT CATCCAGGCACACTGCGGGTGGGCAGCAAAACGATTCGAGATCACCGTGATTACGGTGTTATCGATATCACCACTGTGCT CACTAAAAGTTCCAACGTGGGGACCAGCAAGCTGGCGTTAGCCATGGATTCGCAGGCATTGCCGGGCTACCTGGAGCGCT TTGGTTTCGGGCAATCCACCCACATTGCGTTTCCTGGCGAAAGCGATGGGCTGTTGCCGCTGCGCAGTAAATGGCGCGAT GTTGAACGAGCGGCCCTGTCCTATGGTTACGGTTTGAGTGTCTCTGCGGTGCAGTTGGCTCAGGCCTATGCGGTGATCGC TAACGATGGCGTCAAAGTGCCGTTGACCTTGAAGAAAGTGGATCAGCCGCCGCAGGGTGAGCAGGTGATCGGCAAGGCGA CGGCTCGCCAGCTGGTACAGATGTTGGAAACGGTGGTCAGTCGTGTTGGCACCGCGCGCCGGGCCCAGGTGCCAGGCTAT CAGGTGGCAGGCAAGACCGGCACCGTGCACAAGGTGGTGAACGGTGGTTACGCCGATGATAACTATATTGGTCTGTTTGC TGGGTTGGCCCCGGCAACGGACCCGCGCATTGTCACCGTGGTGGTGATTGATGATCCGGCGGGTGATGCCTATTACGGTG GGCTCGTTGCGGCGCCGGCATTTTCTCGCATTATGAGTGGCGTGTTGCGCTCGCTCCATGTGCCACCGGACAAGCCTGAC GGGCTGCTGGCCGGCGGGCCGGACGGGGAGGATCGCTCATGA
Upstream 100 bases:
>100_bases AGCACAGCACCTGGGGTAGTTACGCCCGGGTGGAGCGCCTGGCTAGAGAAAAGCTGGGCATGAAGTTACCTAAGACGAAT GAGAGAGTGCTGATCAGGCC
Downstream 100 bases:
>100_bases TGACTCTCCAGCAACTGCTGCCTAATACCACCCTGCCTGCTACTGCGGCGGGTGTTGTGCTTTCAGGGTTACAGCTCGAT AGCCGCAAAGTTATGCCCGG
Product: penicillin-binding protein 3
Products: NA
Alternate protein names: Penicillin-binding protein 3; PBP-3; Peptidoglycan glycosyltransferase 3 [H]
Number of amino acids: Translated: 573; Mature: 573
Protein sequence:
>573_residues MKKQARKIRQPNHLMRWRFVLGFWSVCACLLLIRAVDLQVIQHDFLAHQGDIRNLRVEPLAAHRGVIRDRAGKPLAVSTP VVTLWVNPREAMEHQDQWGRLAGNSVIDQKAFARKVRRHKSREFIYLERGLAPETAKTVLSLNVPGVYALTEYRRYYPAG EVASHVVGFTNIDDQGQEGIELALEDHLSGHSGRKKVVRDLLGRVIQDIEVLEPAEPGEDVTLSIDLRLQYLAYRELLGA VQKFNAKGGSAVVLDVRTGEVLAMVNQPAYNPNNRGNLDTGALRNRAVTDLFEPGSTMKPFTVAAALEMGMVTPSTTINT HPGTLRVGSKTIRDHRDYGVIDITTVLTKSSNVGTSKLALAMDSQALPGYLERFGFGQSTHIAFPGESDGLLPLRSKWRD VERAALSYGYGLSVSAVQLAQAYAVIANDGVKVPLTLKKVDQPPQGEQVIGKATARQLVQMLETVVSRVGTARRAQVPGY QVAGKTGTVHKVVNGGYADDNYIGLFAGLAPATDPRIVTVVVIDDPAGDAYYGGLVAAPAFSRIMSGVLRSLHVPPDKPD GLLAGGPDGEDRS
Sequences:
>Translated_573_residues MKKQARKIRQPNHLMRWRFVLGFWSVCACLLLIRAVDLQVIQHDFLAHQGDIRNLRVEPLAAHRGVIRDRAGKPLAVSTP VVTLWVNPREAMEHQDQWGRLAGNSVIDQKAFARKVRRHKSREFIYLERGLAPETAKTVLSLNVPGVYALTEYRRYYPAG EVASHVVGFTNIDDQGQEGIELALEDHLSGHSGRKKVVRDLLGRVIQDIEVLEPAEPGEDVTLSIDLRLQYLAYRELLGA VQKFNAKGGSAVVLDVRTGEVLAMVNQPAYNPNNRGNLDTGALRNRAVTDLFEPGSTMKPFTVAAALEMGMVTPSTTINT HPGTLRVGSKTIRDHRDYGVIDITTVLTKSSNVGTSKLALAMDSQALPGYLERFGFGQSTHIAFPGESDGLLPLRSKWRD VERAALSYGYGLSVSAVQLAQAYAVIANDGVKVPLTLKKVDQPPQGEQVIGKATARQLVQMLETVVSRVGTARRAQVPGY QVAGKTGTVHKVVNGGYADDNYIGLFAGLAPATDPRIVTVVVIDDPAGDAYYGGLVAAPAFSRIMSGVLRSLHVPPDKPD GLLAGGPDGEDRS >Mature_573_residues MKKQARKIRQPNHLMRWRFVLGFWSVCACLLLIRAVDLQVIQHDFLAHQGDIRNLRVEPLAAHRGVIRDRAGKPLAVSTP VVTLWVNPREAMEHQDQWGRLAGNSVIDQKAFARKVRRHKSREFIYLERGLAPETAKTVLSLNVPGVYALTEYRRYYPAG EVASHVVGFTNIDDQGQEGIELALEDHLSGHSGRKKVVRDLLGRVIQDIEVLEPAEPGEDVTLSIDLRLQYLAYRELLGA VQKFNAKGGSAVVLDVRTGEVLAMVNQPAYNPNNRGNLDTGALRNRAVTDLFEPGSTMKPFTVAAALEMGMVTPSTTINT HPGTLRVGSKTIRDHRDYGVIDITTVLTKSSNVGTSKLALAMDSQALPGYLERFGFGQSTHIAFPGESDGLLPLRSKWRD VERAALSYGYGLSVSAVQLAQAYAVIANDGVKVPLTLKKVDQPPQGEQVIGKATARQLVQMLETVVSRVGTARRAQVPGY QVAGKTGTVHKVVNGGYADDNYIGLFAGLAPATDPRIVTVVVIDDPAGDAYYGGLVAAPAFSRIMSGVLRSLHVPPDKPD GLLAGGPDGEDRS
Specific function: Cell wall formation. Essential for the formation of a septum of the murein sacculus. Synthesis of cross-linked peptidoglycan from the lipid intermediates [H]
COG id: COG0768
COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2
Gene ontology:
Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side. Note=The bulk of the molecule, except for the N-terminal membrane anchor region, protrudes into the periplasmic space, where it acts on murein (By similarity) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI1786272, Length=568, Percent_Identity=44.3661971830986, Blast_Score=472, Evalue=1e-134, Organism=Escherichia coli, GI1786854, Length=618, Percent_Identity=27.0226537216829, Blast_Score=151, Evalue=1e-37,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR005311 - InterPro: IPR001460 [H]
Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase [H]
EC number: =2.4.1.129 [H]
Molecular weight: Translated: 62334; Mature: 62334
Theoretical pI: Translated: 9.55; Mature: 9.55
Prosite motif: PS00013 PROKAR_LIPOPROTEIN
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 1.7 %Met (Translated Protein) 2.1 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 1.7 %Met (Mature Protein) 2.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKKQARKIRQPNHLMRWRFVLGFWSVCACLLLIRAVDLQVIQHDFLAHQGDIRNLRVEPL CCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCH AAHRGVIRDRAGKPLAVSTPVVTLWVNPREAMEHQDQWGRLAGNSVIDQKAFARKVRRHK HHHCCHHHHCCCCCEEEECCEEEEEECHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC SREFIYLERGLAPETAKTVLSLNVPGVYALTEYRRYYPAGEVASHVVGFTNIDDQGQEGI CCCEEEEECCCCCHHHHEEEEECCCCCHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCHH ELALEDHLSGHSGRKKVVRDLLGRVIQDIEVLEPAEPGEDVTLSIDLRLQYLAYRELLGA HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEHHHHHHHHHHHH VQKFNAKGGSAVVLDVRTGEVLAMVNQPAYNPNNRGNLDTGALRNRAVTDLFEPGSTMKP HHHHCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCC FTVAAALEMGMVTPSTTINTHPGTLRVGSKTIRDHRDYGVIDITTVLTKSSNVGTSKLAL HHHHHHHHHCCCCCCCEECCCCCEEEECCHHHHHCCCCCEEEEEEEEECCCCCCCHHEEE AMDSQALPGYLERFGFGQSTHIAFPGESDGLLPLRSKWRDVERAALSYGYGLSVSAVQLA EECCCCCHHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHH QAYAVIANDGVKVPLTLKKVDQPPQGEQVIGKATARQLVQMLETVVSRVGTARRAQVPGY HHHHEEECCCEEEEEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCE QVAGKTGTVHKVVNGGYADDNYIGLFAGLAPATDPRIVTVVVIDDPAGDAYYGGLVAAPA EECCCCCCCHHHHCCCCCCCCCEEEEECCCCCCCCEEEEEEEEECCCCCCHHCCCHHHHH FSRIMSGVLRSLHVPPDKPDGLLAGGPDGEDRS HHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCC >Mature Secondary Structure MKKQARKIRQPNHLMRWRFVLGFWSVCACLLLIRAVDLQVIQHDFLAHQGDIRNLRVEPL CCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCH AAHRGVIRDRAGKPLAVSTPVVTLWVNPREAMEHQDQWGRLAGNSVIDQKAFARKVRRHK HHHCCHHHHCCCCCEEEECCEEEEEECHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC SREFIYLERGLAPETAKTVLSLNVPGVYALTEYRRYYPAGEVASHVVGFTNIDDQGQEGI CCCEEEEECCCCCHHHHEEEEECCCCCHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCHH ELALEDHLSGHSGRKKVVRDLLGRVIQDIEVLEPAEPGEDVTLSIDLRLQYLAYRELLGA HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEHHHHHHHHHHHH VQKFNAKGGSAVVLDVRTGEVLAMVNQPAYNPNNRGNLDTGALRNRAVTDLFEPGSTMKP HHHHCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCC FTVAAALEMGMVTPSTTINTHPGTLRVGSKTIRDHRDYGVIDITTVLTKSSNVGTSKLAL HHHHHHHHHCCCCCCCEECCCCCEEEECCHHHHHCCCCCEEEEEEEEECCCCCCCHHEEE AMDSQALPGYLERFGFGQSTHIAFPGESDGLLPLRSKWRDVERAALSYGYGLSVSAVQLA EECCCCCHHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHH QAYAVIANDGVKVPLTLKKVDQPPQGEQVIGKATARQLVQMLETVVSRVGTARRAQVPGY HHHHEEECCCEEEEEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCE QVAGKTGTVHKVVNGGYADDNYIGLFAGLAPATDPRIVTVVVIDDPAGDAYYGGLVAAPA EECCCCCCCHHHHCCCCCCCCCEEEEECCCCCCCCEEEEEEEEECCCCCCHHCCCHHHHH FSRIMSGVLRSLHVPPDKPDGLLAGGPDGEDRS HHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]