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The map label for this gene is rsmH

Identifier: 110833451

GI number: 110833451

Start: 646661

End: 647599

Strand: Direct

Name: rsmH

Synonym: ABO_0590

Alternate gene names: 110833451

Gene position: 646661-647599 (Clockwise)

Preceding gene: 110833450

Following gene: 110833452

Centisome position: 20.73

GC content: 58.36

Gene sequence:

>939_bases
ATGACGACCGAGGACACGCAGTACGCACACCAGCCGGTAATGCTGGAAGAGGTGCTGGATATGTGGTTCAGCCAGAGCGA
AGGGTTTTATGTGGACGGCACTTTTGGTCGTGGTGGCCACAGCCGTGCCTTGCTTTCGCGCCTGGGTGAAAACGGTCGCC
TTATCGGTATTGATCGCGACCCGCAAGCAATTGCTGCTGGCCAGCAATTGGCTGCTAGCGATAGCCGTTTTCATATGATG
GCCGGCCGCTTTGACTGCCTGCCACAAGCGGTGGAGCAGGCCGGTCGGCCGATTGACGGTTTGTTGCTGGATCTGGGCGT
TTCTTCGCCACAGCTGGATGATGCGGCGCGCGGTTTCAGTTTTCTGCGTGACGGTCCTCTCGATATGCGCATGGACCCGA
CCCAAGGCGAGAGCGTGGCCGAATGGTTGTCCTACGCAGCGGAAAAAGATATCGCCAATGTGCTGTATCGCTACGGCGAA
GAGCGCAAGTCTCGTTGGATCGCCAAGCGTATTTGTGAAACCCGCAAAGAGCAGCCGATTACCCGCACCCTGCAGTTGGC
CGACTTGATCGAGTCCGTGCTGGGGCGTAATGAGCAGGGTAAGCATCCGGCGACGCGCAGCTTTCAGGCCCTGCGAATAC
ATATAAACGGGGAGCTGGATGCACTGGATCAGGTGCTCGAACAGTCCCTCGAGACGCTCGCCATCGGCGGGCGTCTCGCC
ATTATTAGCTTCCATTCTTTGGAAGACCGGATCGTGAAATTATTTATTCGTGATCATTCCGGCCGGGCACCGAAAGGGCG
CGGTGGTCTGCCGTTGGGTGATGAACTGCCTCAGCGGCTGGAGCCGGTGGGTAAGGTCATGCGGGCCAGCAAGGCTGAGC
TGAAAGTGAATGTGCGCTCGCGTAGTGCGGTGCTGCGTATTGCGGAGAAGGTGGCCTGA

Upstream 100 bases:

>100_bases
TGCACCGTTTTGAAATCTGGAAAGAAGAGAGTTGGGCCGATGTGGATGGCACCCTGGACCCGGCAGCGTTGCCGGAAAGC
GTGCAGGAGCTGTCGTTCTG

Downstream 100 bases:

>100_bases
TGGCGGCGCCGTGGATGATTCGCGTATTGGTCGTGATGGTCGTGATGTCTGCGCTGGGTGTCAGTTATAGCGTGCATCAG
GCGCGGCGTCTCACGGATGA

Product: methyltransferase

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MTTEDTQYAHQPVMLEEVLDMWFSQSEGFYVDGTFGRGGHSRALLSRLGENGRLIGIDRDPQAIAAGQQLAASDSRFHMM
AGRFDCLPQAVEQAGRPIDGLLLDLGVSSPQLDDAARGFSFLRDGPLDMRMDPTQGESVAEWLSYAAEKDIANVLYRYGE
ERKSRWIAKRICETRKEQPITRTLQLADLIESVLGRNEQGKHPATRSFQALRIHINGELDALDQVLEQSLETLAIGGRLA
IISFHSLEDRIVKLFIRDHSGRAPKGRGGLPLGDELPQRLEPVGKVMRASKAELKVNVRSRSAVLRIAEKVA

Sequences:

>Translated_312_residues
MTTEDTQYAHQPVMLEEVLDMWFSQSEGFYVDGTFGRGGHSRALLSRLGENGRLIGIDRDPQAIAAGQQLAASDSRFHMM
AGRFDCLPQAVEQAGRPIDGLLLDLGVSSPQLDDAARGFSFLRDGPLDMRMDPTQGESVAEWLSYAAEKDIANVLYRYGE
ERKSRWIAKRICETRKEQPITRTLQLADLIESVLGRNEQGKHPATRSFQALRIHINGELDALDQVLEQSLETLAIGGRLA
IISFHSLEDRIVKLFIRDHSGRAPKGRGGLPLGDELPQRLEPVGKVMRASKAELKVNVRSRSAVLRIAEKVA
>Mature_311_residues
TTEDTQYAHQPVMLEEVLDMWFSQSEGFYVDGTFGRGGHSRALLSRLGENGRLIGIDRDPQAIAAGQQLAASDSRFHMMA
GRFDCLPQAVEQAGRPIDGLLLDLGVSSPQLDDAARGFSFLRDGPLDMRMDPTQGESVAEWLSYAAEKDIANVLYRYGEE
RKSRWIAKRICETRKEQPITRTLQLADLIESVLGRNEQGKHPATRSFQALRIHINGELDALDQVLEQSLETLAIGGRLAI
ISFHSLEDRIVKLFIRDHSGRAPKGRGGLPLGDELPQRLEPVGKVMRASKAELKVNVRSRSAVLRIAEKVA

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family

Homologues:

Organism=Homo sapiens, GI165377209, Length=346, Percent_Identity=35.8381502890173, Blast_Score=168, Evalue=5e-42,
Organism=Homo sapiens, GI165377202, Length=192, Percent_Identity=39.0625, Blast_Score=118, Evalue=8e-27,
Organism=Escherichia coli, GI1786270, Length=313, Percent_Identity=53.6741214057508, Blast_Score=312, Evalue=1e-86,
Organism=Drosophila melanogaster, GI62472493, Length=338, Percent_Identity=37.2781065088757, Blast_Score=175, Evalue=4e-44,
Organism=Drosophila melanogaster, GI28571637, Length=338, Percent_Identity=37.2781065088757, Blast_Score=175, Evalue=4e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSMH_ALCBS (Q0VS10)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_692310.1
- ProteinModelPortal:   Q0VS10
- SMR:   Q0VS10
- STRING:   Q0VS10
- GeneID:   4212993
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_0590
- NMPDR:   fig|393595.12.peg.588
- eggNOG:   COG0275
- HOGENOM:   HBG302779
- OMA:   RPINSTL
- PhylomeDB:   Q0VS10
- BioCyc:   ABOR393595:ABO_0590-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01007
- InterPro:   IPR002903
- PANTHER:   PTHR11265
- PIRSF:   PIRSF004486
- TIGRFAMs:   TIGR00006

Pfam domain/function: PF01795 Methyltransf_5

EC number: NA

Molecular weight: Translated: 34656; Mature: 34525

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: BINDING 58-58 BINDING 84-84 BINDING 104-104 BINDING 111-111

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTEDTQYAHQPVMLEEVLDMWFSQSEGFYVDGTFGRGGHSRALLSRLGENGRLIGIDRD
CCCCCCHHHCCCHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHCCCCCCEEEECCC
PQAIAAGQQLAASDSRFHMMAGRFDCLPQAVEQAGRPIDGLLLDLGVSSPQLDDAARGFS
CHHHHHHHHHHCCCCHHHHHHCHHHHHHHHHHHHCCCHHHHHEECCCCCCCCHHHHHHHH
FLRDGPLDMRMDPTQGESVAEWLSYAAEKDIANVLYRYGEERKSRWIAKRICETRKEQPI
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
TRTLQLADLIESVLGRNEQGKHPATRSFQALRIHINGELDALDQVLEQSLETLAIGGRLA
HHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCEEE
IISFHSLEDRIVKLFIRDHSGRAPKGRGGLPLGDELPQRLEPVGKVMRASKAELKVNVRS
EEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHEEEEEHH
RSAVLRIAEKVA
HHHHHHHHHHCC
>Mature Secondary Structure 
TTEDTQYAHQPVMLEEVLDMWFSQSEGFYVDGTFGRGGHSRALLSRLGENGRLIGIDRD
CCCCCHHHCCCHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHCCCCCCEEEECCC
PQAIAAGQQLAASDSRFHMMAGRFDCLPQAVEQAGRPIDGLLLDLGVSSPQLDDAARGFS
CHHHHHHHHHHCCCCHHHHHHCHHHHHHHHHHHHCCCHHHHHEECCCCCCCCHHHHHHHH
FLRDGPLDMRMDPTQGESVAEWLSYAAEKDIANVLYRYGEERKSRWIAKRICETRKEQPI
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
TRTLQLADLIESVLGRNEQGKHPATRSFQALRIHINGELDALDQVLEQSLETLAIGGRLA
HHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCEEE
IISFHSLEDRIVKLFIRDHSGRAPKGRGGLPLGDELPQRLEPVGKVMRASKAELKVNVRS
EEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHEEEEEHH
RSAVLRIAEKVA
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA