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The map label for this gene is mmgC [H]

Identifier: 110833432

GI number: 110833432

Start: 629836

End: 630984

Strand: Direct

Name: mmgC [H]

Synonym: ABO_0571

Alternate gene names: 110833432

Gene position: 629836-630984 (Clockwise)

Preceding gene: 110833431

Following gene: 110833433

Centisome position: 20.19

GC content: 50.13

Gene sequence:

>1149_bases
ATGATGATTCCCCGTACGCTATTTAGTTCTGACCACGAAACTTTTCGCGATACCGTCCGCAAATTTCTTGAAAACGAAGC
CGTGCCATTCAATGAAGAATGGGAGCAGCAAGGCGTGGTCCCCAAAGACGTATGGTTAAAGGCTGGCGAGCAGGGTTTCC
TATGTCCGATGGTGAGTGAGGAGTATGGCGGTATTGGCGCTGACTTCCTTTACAGCGTGGTGATCAATGAAGAAATTTCC
AAGCTGGGCCTCACTGGCATCGGTTGGGGGCTGCACACGGAAATCGTGGCGCCTTACATTGAGCATAATGGCTCAGAAGT
ATTGAAGCAGAAGTATCTGCCGAAAATGGTTACCGGTGAAATGATTGGTGCCATCGCCATGACAGAGCCCGGTGCCGGTT
CTGATTTGCAAGGTGTGAAAACCACGGCAATAAAAGACGGTGACCATTATGTGCTAAACGGCTCTAAAACCTTCATCACT
AATGGCCAGAATGCAGATATCGTCATTGTGGTGGCAAAGACCGACCCGACTAAAGGGGCCAAGGGCATTAGCTTGTTTGT
GGTAGAAACCGACTCTGAAGGGTTCGAGAAAGGTAAGAATCTGAAGAAAGTCGGCATGAAAGCCCAAGATACCTCCGAGC
TGTTCTTCCAGGATGTGCGCGTACCGGCAGAGAACCTGTTGGGTGAAGAGGGCATGGGCTTTATTTATCTGATGAAAGAG
CTGCCCCAGGAACGCCTTGGTATCTCCGTTGGTGGCCTGGCCATGGCCGAGTCTGCATTGGCGCATACCATTGAATATGT
GAAAGAAAGAAAGGCCTTTGGTAAGCCTATCGCTGGCTTCCAGAACACCCAGTTCAAAATTGCCGAAATGCATACCAAGC
TTGAAGTGGCGCGAGCCTATGTGGATCGTTGCTTGGAGCTGCACCTGAAAAAAGAGCTGGATATTCCTACGGCTGCGGCG
GGTAAGTACTACATTACCGATCTGCAGTGTGAAGTGATTGATGAATGCCTACAGTTGCACGGTGGTTACGGTTACATGTG
GGAATACCCGATTGCCCGCATGTTTGCAGATTCACGGGTGCAGCGGATTTACGGCGGCACCAACGAAATTATGAAAGGTA
TTATCGCCAAGGCGGTGCTGGCCGATTAA

Upstream 100 bases:

>100_bases
TTGGTCATTGCTCAACGGCAAGCTCTATCAACATTATGGAGCATTCTCTACCCCTGCCAGCCCGGCGTGGGCCCCCCCGA
TAACCTGACTACCGGAGAGC

Downstream 100 bases:

>100_bases
TTCCGGGTCAGGTCAAAATGAAAGGGCTGCTTCGGCAGCCCTTTTTTTTGTCTTTTTGCGGTTGCCTAATGCATGGATAT
CTCCATCGGGGGCTGCCACA

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MMIPRTLFSSDHETFRDTVRKFLENEAVPFNEEWEQQGVVPKDVWLKAGEQGFLCPMVSEEYGGIGADFLYSVVINEEIS
KLGLTGIGWGLHTEIVAPYIEHNGSEVLKQKYLPKMVTGEMIGAIAMTEPGAGSDLQGVKTTAIKDGDHYVLNGSKTFIT
NGQNADIVIVVAKTDPTKGAKGISLFVVETDSEGFEKGKNLKKVGMKAQDTSELFFQDVRVPAENLLGEEGMGFIYLMKE
LPQERLGISVGGLAMAESALAHTIEYVKERKAFGKPIAGFQNTQFKIAEMHTKLEVARAYVDRCLELHLKKELDIPTAAA
GKYYITDLQCEVIDECLQLHGGYGYMWEYPIARMFADSRVQRIYGGTNEIMKGIIAKAVLAD

Sequences:

>Translated_382_residues
MMIPRTLFSSDHETFRDTVRKFLENEAVPFNEEWEQQGVVPKDVWLKAGEQGFLCPMVSEEYGGIGADFLYSVVINEEIS
KLGLTGIGWGLHTEIVAPYIEHNGSEVLKQKYLPKMVTGEMIGAIAMTEPGAGSDLQGVKTTAIKDGDHYVLNGSKTFIT
NGQNADIVIVVAKTDPTKGAKGISLFVVETDSEGFEKGKNLKKVGMKAQDTSELFFQDVRVPAENLLGEEGMGFIYLMKE
LPQERLGISVGGLAMAESALAHTIEYVKERKAFGKPIAGFQNTQFKIAEMHTKLEVARAYVDRCLELHLKKELDIPTAAA
GKYYITDLQCEVIDECLQLHGGYGYMWEYPIARMFADSRVQRIYGGTNEIMKGIIAKAVLAD
>Mature_382_residues
MMIPRTLFSSDHETFRDTVRKFLENEAVPFNEEWEQQGVVPKDVWLKAGEQGFLCPMVSEEYGGIGADFLYSVVINEEIS
KLGLTGIGWGLHTEIVAPYIEHNGSEVLKQKYLPKMVTGEMIGAIAMTEPGAGSDLQGVKTTAIKDGDHYVLNGSKTFIT
NGQNADIVIVVAKTDPTKGAKGISLFVVETDSEGFEKGKNLKKVGMKAQDTSELFFQDVRVPAENLLGEEGMGFIYLMKE
LPQERLGISVGGLAMAESALAHTIEYVKERKAFGKPIAGFQNTQFKIAEMHTKLEVARAYVDRCLELHLKKELDIPTAAA
GKYYITDLQCEVIDECLQLHGGYGYMWEYPIARMFADSRVQRIYGGTNEIMKGIIAKAVLAD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=380, Percent_Identity=52.6315789473684, Blast_Score=412, Evalue=1e-115,
Organism=Homo sapiens, GI226958412, Length=380, Percent_Identity=37.3684210526316, Blast_Score=259, Evalue=2e-69,
Organism=Homo sapiens, GI226958414, Length=344, Percent_Identity=38.953488372093, Blast_Score=249, Evalue=2e-66,
Organism=Homo sapiens, GI4501859, Length=380, Percent_Identity=34.4736842105263, Blast_Score=241, Evalue=9e-64,
Organism=Homo sapiens, GI4557233, Length=370, Percent_Identity=36.2162162162162, Blast_Score=231, Evalue=7e-61,
Organism=Homo sapiens, GI7656849, Length=380, Percent_Identity=33.6842105263158, Blast_Score=227, Evalue=1e-59,
Organism=Homo sapiens, GI187960098, Length=374, Percent_Identity=32.620320855615, Blast_Score=211, Evalue=7e-55,
Organism=Homo sapiens, GI4557231, Length=374, Percent_Identity=32.620320855615, Blast_Score=211, Evalue=7e-55,
Organism=Homo sapiens, GI76496475, Length=376, Percent_Identity=35.1063829787234, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI4557235, Length=376, Percent_Identity=35.1063829787234, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI21361497, Length=376, Percent_Identity=34.5744680851064, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI4503943, Length=381, Percent_Identity=27.5590551181102, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI7669494, Length=312, Percent_Identity=29.1666666666667, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI211971008, Length=285, Percent_Identity=29.4736842105263, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI48976061, Length=285, Percent_Identity=29.4736842105263, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI38505218, Length=294, Percent_Identity=29.2517006802721, Blast_Score=102, Evalue=6e-22,
Organism=Escherichia coli, GI87081958, Length=385, Percent_Identity=31.4285714285714, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1786223, Length=379, Percent_Identity=26.9129287598945, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI87082384, Length=271, Percent_Identity=28.7822878228782, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI87081702, Length=334, Percent_Identity=25.1497005988024, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17538396, Length=386, Percent_Identity=35.4922279792746, Blast_Score=251, Evalue=5e-67,
Organism=Caenorhabditis elegans, GI17533517, Length=379, Percent_Identity=36.1477572559367, Blast_Score=236, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI17570075, Length=386, Percent_Identity=34.1968911917098, Blast_Score=229, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI17569725, Length=379, Percent_Identity=35.0923482849604, Blast_Score=228, Evalue=5e-60,
Organism=Caenorhabditis elegans, GI17508101, Length=377, Percent_Identity=34.4827586206897, Blast_Score=227, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI17551932, Length=379, Percent_Identity=33.7730870712401, Blast_Score=214, Evalue=6e-56,
Organism=Caenorhabditis elegans, GI17534899, Length=366, Percent_Identity=33.3333333333333, Blast_Score=214, Evalue=8e-56,
Organism=Caenorhabditis elegans, GI17505929, Length=376, Percent_Identity=34.5744680851064, Blast_Score=213, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI17506239, Length=380, Percent_Identity=32.1052631578947, Blast_Score=211, Evalue=6e-55,
Organism=Caenorhabditis elegans, GI71990804, Length=253, Percent_Identity=41.1067193675889, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI71985184, Length=351, Percent_Identity=34.7578347578348, Blast_Score=181, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI71982178, Length=281, Percent_Identity=33.4519572953737, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI32563615, Length=225, Percent_Identity=34.6666666666667, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI71985192, Length=309, Percent_Identity=34.9514563106796, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17531909, Length=244, Percent_Identity=31.1475409836066, Blast_Score=124, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI17534353, Length=294, Percent_Identity=31.6326530612245, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17562446, Length=295, Percent_Identity=28.135593220339, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17531913, Length=179, Percent_Identity=26.2569832402235, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21355753, Length=379, Percent_Identity=36.4116094986807, Blast_Score=233, Evalue=1e-61,
Organism=Drosophila melanogaster, GI21356377, Length=376, Percent_Identity=34.3085106382979, Blast_Score=232, Evalue=3e-61,
Organism=Drosophila melanogaster, GI24666513, Length=383, Percent_Identity=33.1592689295039, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI24660351, Length=376, Percent_Identity=32.9787234042553, Blast_Score=209, Evalue=3e-54,
Organism=Drosophila melanogaster, GI24646207, Length=377, Percent_Identity=33.6870026525199, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI281363737, Length=345, Percent_Identity=34.4927536231884, Blast_Score=177, Evalue=2e-44,
Organism=Drosophila melanogaster, GI19920834, Length=374, Percent_Identity=28.6096256684492, Blast_Score=123, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 42254; Mature: 42254

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMIPRTLFSSDHETFRDTVRKFLENEAVPFNEEWEQQGVVPKDVWLKAGEQGFLCPMVSE
CCCCCHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCHHHHHHCCCCCCCCCCCCH
EYGGIGADFLYSVVINEEISKLGLTGIGWGLHTEIVAPYIEHNGSEVLKQKYLPKMVTGE
HCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCHHHHHH
MIGAIAMTEPGAGSDLQGVKTTAIKDGDHYVLNGSKTFITNGQNADIVIVVAKTDPTKGA
HHCEEEECCCCCCCCCCCCEEEEEECCCEEEECCCEEEEECCCCCCEEEEEEECCCCCCC
KGISLFVVETDSEGFEKGKNLKKVGMKAQDTSELFFQDVRVPAENLLGEEGMGFIYLMKE
CCEEEEEEECCCCHHHHCCCHHHHCCCCCCHHHHHHHHHCCCHHHHCCCCCCCCHHHHHH
LPQERLGISVGGLAMAESALAHTIEYVKERKAFGKPIAGFQNTQFKIAEMHTKLEVARAY
CCHHHHCEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHH
VDRCLELHLKKELDIPTAAAGKYYITDLQCEVIDECLQLHGGYGYMWEYPIARMFADSRV
HHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHH
QRIYGGTNEIMKGIIAKAVLAD
HHHHCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMIPRTLFSSDHETFRDTVRKFLENEAVPFNEEWEQQGVVPKDVWLKAGEQGFLCPMVSE
CCCCCHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCHHHHHHCCCCCCCCCCCCH
EYGGIGADFLYSVVINEEISKLGLTGIGWGLHTEIVAPYIEHNGSEVLKQKYLPKMVTGE
HCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCHHHHHH
MIGAIAMTEPGAGSDLQGVKTTAIKDGDHYVLNGSKTFITNGQNADIVIVVAKTDPTKGA
HHCEEEECCCCCCCCCCCCEEEEEECCCEEEECCCEEEEECCCCCCEEEEEEECCCCCCC
KGISLFVVETDSEGFEKGKNLKKVGMKAQDTSELFFQDVRVPAENLLGEEGMGFIYLMKE
CCEEEEEEECCCCHHHHCCCHHHHCCCCCCHHHHHHHHHCCCHHHHCCCCCCCCHHHHHH
LPQERLGISVGGLAMAESALAHTIEYVKERKAFGKPIAGFQNTQFKIAEMHTKLEVARAY
CCHHHHCEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHH
VDRCLELHLKKELDIPTAAAGKYYITDLQCEVIDECLQLHGGYGYMWEYPIARMFADSRV
HHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHH
QRIYGGTNEIMKGIIAKAVLAD
HHHHCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]