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The map label for this gene is pmbA [H]

Identifier: 110833401

GI number: 110833401

Start: 594930

End: 596285

Strand: Direct

Name: pmbA [H]

Synonym: ABO_0540

Alternate gene names: 110833401

Gene position: 594930-596285 (Clockwise)

Preceding gene: 110833399

Following gene: 110833419

Centisome position: 19.07

GC content: 57.23

Gene sequence:

>1356_bases
ATGTCTGATTCCTCCGCAACGACAGCCGAACTCGACAATACGCAGCTAGAACAGGCAAAAGATACTGCTGCCTGGCTGAT
AGAAGAGGCAAAACGCCAGGGCGCCGATGCGGCGGAAGTGGGTGTGAGCCTGTCCCAGGGCTATTCGGTAAATGTGCGCC
AGGGAGAGGTGGAGACGGTGGAATTCCACCGTGACCGTGGGGTTTCCGTCACCGTGTACAAGGGTCTGCGTAAAGGTCAC
GCCAGTAGCTCCGACGATAATCGTGACAGTTTGCGCGATACCTTAGCGGCGGCCACGGCCATTGCTGGTTACACCGAAGA
GGATCGTTATGCGGGCCTAGCGCCAGCCAATCAGCTGGCTAGCGACGTGGCGAACCTAGATCTGTACCACCCCTGGGCCA
TGGATACCCAATCCGCCATTGAGGACGCTCTGCATTGTGAAGCGGTAGCTCGTGATGACGCTCGTATCGTCAATTCTGAA
GGGGCGTCAGTGAACAGTGGCGCTAGCCTAAGGGTGTATGCCACCTCGGAAGGTTTTCTGCATGGCTATCGTGGCACTAA
CCATAGCCGCGTGTGCAGCGTCGTTGCAGAGGATGATGCCGGCATGCAGCGTGATTATTGGTATGACGGTGGACGGGTGG
GTGATCAGTTGGCTTCAGCTGAAGAGGTGGGCCTGCGTGCTCGTGAGCGCGCGCTGGCTCGCCTGGGGGCACAAGTGCCG
GAGACTGGTGAGCTGCCGGTGATTTTTGCGCCAGAGGTGGCTTCAGGTTTGCTCGGGCATCTGGTGTCTGCTATCAGTGG
TGGTGCACTTTATCGCCGTAGTTCTTTTTTGCAGGATAGCCTGGGCAAGCCAGTGTTACCGGCCGGTTTTCAGCTAACGG
AAAATCCTCACCTGCCGGCGGGTAACGCGTCAGCGCCTTTCGATGGAGATGGTCTGCCCACGCGGCCTCAAGCGTTTGTA
GAAGATGGTGTGCTGAAACAGTATGCGTTGGGGCTCTATGCCAGCCGGCGGCTGAATATGGCTCCCACCGGCAATGGCGG
AGGGGTACGTAATGTGCGCCTCACTGACACCGGTGATTCGCTGGCCGCGCTGATGGCCAAGGTTCCCAAAGGTATTCTAA
TTACCGAAGTCATGGGCCAGGGTATTAATTTGGTGACCGGGGATTACTCCCGTGGGGCAAGCGGTTTTTGGTTTGAGAAT
GGTGTTGTAAAAGGTGCACTACAAGAGTTTACCATTGCCGGCCATCTGGGAGAGATGCTCAGAGGCATCCAAGGGAGCGG
TACGGATGTGGACTATCGCGGCAATATTGCCTGTGGGTCTCTGCTGCTGTCGCCCATTAAGGTGGCTGGCCGATAA

Upstream 100 bases:

>100_bases
AAGGCATTGTCTTCGCGTTTTTGCTGGCCCTTGCTGGTGATTTGCTCGTCGCTATACTCGGTCATAACTGTTTAATACCC
ATCAATGGAACCGCTATTTT

Downstream 100 bases:

>100_bases
GTTGCCCCTGTGATTCGTTTGTTTTTTGGCTAGGGGAAAGGCCAATAATGGCCTGCCTTCTTTGTCACGCTAGTAGGTGG
GCATAGAGCACCGTGGCCAG

Product: pmbA protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MSDSSATTAELDNTQLEQAKDTAAWLIEEAKRQGADAAEVGVSLSQGYSVNVRQGEVETVEFHRDRGVSVTVYKGLRKGH
ASSSDDNRDSLRDTLAAATAIAGYTEEDRYAGLAPANQLASDVANLDLYHPWAMDTQSAIEDALHCEAVARDDARIVNSE
GASVNSGASLRVYATSEGFLHGYRGTNHSRVCSVVAEDDAGMQRDYWYDGGRVGDQLASAEEVGLRARERALARLGAQVP
ETGELPVIFAPEVASGLLGHLVSAISGGALYRRSSFLQDSLGKPVLPAGFQLTENPHLPAGNASAPFDGDGLPTRPQAFV
EDGVLKQYALGLYASRRLNMAPTGNGGGVRNVRLTDTGDSLAALMAKVPKGILITEVMGQGINLVTGDYSRGASGFWFEN
GVVKGALQEFTIAGHLGEMLRGIQGSGTDVDYRGNIACGSLLLSPIKVAGR

Sequences:

>Translated_451_residues
MSDSSATTAELDNTQLEQAKDTAAWLIEEAKRQGADAAEVGVSLSQGYSVNVRQGEVETVEFHRDRGVSVTVYKGLRKGH
ASSSDDNRDSLRDTLAAATAIAGYTEEDRYAGLAPANQLASDVANLDLYHPWAMDTQSAIEDALHCEAVARDDARIVNSE
GASVNSGASLRVYATSEGFLHGYRGTNHSRVCSVVAEDDAGMQRDYWYDGGRVGDQLASAEEVGLRARERALARLGAQVP
ETGELPVIFAPEVASGLLGHLVSAISGGALYRRSSFLQDSLGKPVLPAGFQLTENPHLPAGNASAPFDGDGLPTRPQAFV
EDGVLKQYALGLYASRRLNMAPTGNGGGVRNVRLTDTGDSLAALMAKVPKGILITEVMGQGINLVTGDYSRGASGFWFEN
GVVKGALQEFTIAGHLGEMLRGIQGSGTDVDYRGNIACGSLLLSPIKVAGR
>Mature_450_residues
SDSSATTAELDNTQLEQAKDTAAWLIEEAKRQGADAAEVGVSLSQGYSVNVRQGEVETVEFHRDRGVSVTVYKGLRKGHA
SSSDDNRDSLRDTLAAATAIAGYTEEDRYAGLAPANQLASDVANLDLYHPWAMDTQSAIEDALHCEAVARDDARIVNSEG
ASVNSGASLRVYATSEGFLHGYRGTNHSRVCSVVAEDDAGMQRDYWYDGGRVGDQLASAEEVGLRARERALARLGAQVPE
TGELPVIFAPEVASGLLGHLVSAISGGALYRRSSFLQDSLGKPVLPAGFQLTENPHLPAGNASAPFDGDGLPTRPQAFVE
DGVLKQYALGLYASRRLNMAPTGNGGGVRNVRLTDTGDSLAALMAKVPKGILITEVMGQGINLVTGDYSRGASGFWFENG
VVKGALQEFTIAGHLGEMLRGIQGSGTDVDYRGNIACGSLLLSPIKVAGR

Specific function: May facilitate the secretion of the peptide antibiotic microcin B17 (MccB17) by completing its maturation. Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1790682, Length=437, Percent_Identity=45.0800915331808, Blast_Score=363, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 47615; Mature: 47484

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSSATTAELDNTQLEQAKDTAAWLIEEAKRQGADAAEVGVSLSQGYSVNVRQGEVETV
CCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCEEEEECCCEEEE
EFHRDRGVSVTVYKGLRKGHASSSDDNRDSLRDTLAAATAIAGYTEEDRYAGLAPANQLA
EECCCCCCEEEEEHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
SDVANLDLYHPWAMDTQSAIEDALHCEAVARDDARIVNSEGASVNSGASLRVYATSEGFL
HHHHCCCEECCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCEEEEEECCCCCE
HGYRGTNHSRVCSVVAEDDAGMQRDYWYDGGRVGDQLASAEEVGLRARERALARLGAQVP
ECCCCCCHHHEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ETGELPVIFAPEVASGLLGHLVSAISGGALYRRSSFLQDSLGKPVLPAGFQLTENPHLPA
CCCCCCEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCC
GNASAPFDGDGLPTRPQAFVEDGVLKQYALGLYASRRLNMAPTGNGGGVRNVRLTDTGDS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCHH
LAALMAKVPKGILITEVMGQGINLVTGDYSRGASGFWFENGVVKGALQEFTIAGHLGEML
HHHHHHHCCCCEEEHHHHCCCCEEEECCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHH
RGIQGSGTDVDYRGNIACGSLLLSPIKVAGR
HCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SDSSATTAELDNTQLEQAKDTAAWLIEEAKRQGADAAEVGVSLSQGYSVNVRQGEVETV
CCCCCCEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCEEEEECCCEEEE
EFHRDRGVSVTVYKGLRKGHASSSDDNRDSLRDTLAAATAIAGYTEEDRYAGLAPANQLA
EECCCCCCEEEEEHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
SDVANLDLYHPWAMDTQSAIEDALHCEAVARDDARIVNSEGASVNSGASLRVYATSEGFL
HHHHCCCEECCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCEEEEEECCCCCE
HGYRGTNHSRVCSVVAEDDAGMQRDYWYDGGRVGDQLASAEEVGLRARERALARLGAQVP
ECCCCCCHHHEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ETGELPVIFAPEVASGLLGHLVSAISGGALYRRSSFLQDSLGKPVLPAGFQLTENPHLPA
CCCCCCEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCC
GNASAPFDGDGLPTRPQAFVEDGVLKQYALGLYASRRLNMAPTGNGGGVRNVRLTDTGDS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCHH
LAALMAKVPKGILITEVMGQGINLVTGDYSRGASGFWFENGVVKGALQEFTIAGHLGEML
HHHHHHHCCCCEEEHHHHCCCCEEEECCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHH
RGIQGSGTDVDYRGNIACGSLLLSPIKVAGR
HCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]