Click here to switch to the map view.

The map label for this gene is crp [C]

Identifier: 110833398

GI number: 110833398

Start: 592342

End: 592803

Strand: Direct

Name: crp [C]

Synonym: ABO_0537

Alternate gene names: 110833398

Gene position: 592342-592803 (Clockwise)

Preceding gene: 110833397

Following gene: 110833399

Centisome position: 18.98

GC content: 53.03

Gene sequence:

>462_bases
ATGTCCCAGGTGCTGGATATTCTGTCGCGTATGCGGCTGTTTGCCGGTCTGAGCGAGGACGAATTAGCAATATTGGAAAA
ACTAGTGTTCGTCAATCGGGTGCCAGTGGGTGATGTGGTTTGCCGCGAAGGGGACCGTAGCGATTTTGTTTGTTTTGTGG
TGCGAGGTTGCCTGGATATTGTGAAGAACAATGAGGGAGGCGGTGAAGTGGTGATTGCCCACCTGCGACCCGGTGATTGC
ATGGGGGAAATGGCATTGGTGGATCATGAGCCACGGTCGGCAACGGTGCGTGCCGCAGAAGACGCTACTTTGATTGTGTT
GACCCGCAAAGGGATTGAACAGTTACGCAAACGCAGCCCTCATGCGGTGAGCTTGGTGATGGAAAATATTGCTCGCCTGT
TATGCACTCACCTGCGTCGTACATCGTCCCAGCTGGCACAATTTAAACTGCCGGTGGGTTAA

Upstream 100 bases:

>100_bases
CTGGAATTGGCGTGTGCGGTAAAGATGGTCAATCCGTGCCGGTGGGGGTAGGGCAGCCGACGCTGCGCGTGGATGCTTTG
ACCGTCGGAGGCACGGCCTG

Downstream 100 bases:

>100_bases
TGAAGAGCCGTTGCTTATGAGAACGCTTTGTCTGTTTGTGTGGCTAATGTTGCTGGCGGCCTGTGATCCGGGACAGTTAC
CTGCGGATGTGCGGCTGCCC

Product: cyclic nucleotide-binding protein

Products: NA

Alternate protein names: Catabolite Gene Activator; Cyclic AMP Receptor Protein; Crp Family Transcriptional Regulator; Crp/FNR Family Transcriptional Regulator; CAMP-Dependent Transcriptional Regulator; CAAX Amino Terminal Protease Family; Phosphoprotein Phosphatase; Crp/Fnr Family Transcriptional Regulator; CAMP-Dependent Protein Kinase Regulatory Subunit; MscS Mechanosensitive Ion Channel

Number of amino acids: Translated: 153; Mature: 152

Protein sequence:

>153_residues
MSQVLDILSRMRLFAGLSEDELAILEKLVFVNRVPVGDVVCREGDRSDFVCFVVRGCLDIVKNNEGGGEVVIAHLRPGDC
MGEMALVDHEPRSATVRAAEDATLIVLTRKGIEQLRKRSPHAVSLVMENIARLLCTHLRRTSSQLAQFKLPVG

Sequences:

>Translated_153_residues
MSQVLDILSRMRLFAGLSEDELAILEKLVFVNRVPVGDVVCREGDRSDFVCFVVRGCLDIVKNNEGGGEVVIAHLRPGDC
MGEMALVDHEPRSATVRAAEDATLIVLTRKGIEQLRKRSPHAVSLVMENIARLLCTHLRRTSSQLAQFKLPVG
>Mature_152_residues
SQVLDILSRMRLFAGLSEDELAILEKLVFVNRVPVGDVVCREGDRSDFVCFVVRGCLDIVKNNEGGGEVVIAHLRPGDCM
GEMALVDHEPRSATVRAAEDATLIVLTRKGIEQLRKRSPHAVSLVMENIARLLCTHLRRTSSQLAQFKLPVG

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 16893; Mature: 16762

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: PS00889 CNMP_BINDING_2 ; PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQVLDILSRMRLFAGLSEDELAILEKLVFVNRVPVGDVVCREGDRSDFVCFVVRGCLDI
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCCCCCHHHHHHHHHHHH
VKNNEGGGEVVIAHLRPGDCMGEMALVDHEPRSATVRAAEDATLIVLTRKGIEQLRKRSP
HHCCCCCCEEEEEEECCCCCCCCHHHCCCCCCCCEEEECCCCEEEEEEHHHHHHHHHCCC
HAVSLVMENIARLLCTHLRRTSSQLAQFKLPVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SQVLDILSRMRLFAGLSEDELAILEKLVFVNRVPVGDVVCREGDRSDFVCFVVRGCLDI
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCCCCCHHHHHHHHHHHH
VKNNEGGGEVVIAHLRPGDCMGEMALVDHEPRSATVRAAEDATLIVLTRKGIEQLRKRSP
HHCCCCCCEEEEEEECCCCCCCCHHHCCCCCCCCEEEECCCCEEEEEEHHHHHHHHHCCC
HAVSLVMENIARLLCTHLRRTSSQLAQFKLPVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA