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The map label for this gene is htpG

Identifier: 110680847

GI number: 110680847

Start: 3560335

End: 3562200

Strand: Direct

Name: htpG

Synonym: RD1_3696

Alternate gene names: 110680847

Gene position: 3560335-3562200 (Clockwise)

Preceding gene: 110680846

Following gene: 110680848

Centisome position: 86.14

GC content: 56.7

Gene sequence:

>1866_bases
ATGACTGATGCAAGCGTAAAAGAAACATTTTCCTTTCAGACGGAAGTGGGTCAGCTTCTGGATATCGTTGCTGGATCCCT
TTACTCCAATCGTGAGATCTTCCTGCGGGAACTGGTGTCCAACGCCTCGGACGCCTGCGACAAACTCCGCTATGAGGCGC
TGACGAACCCGTCCCTTGCACAAAATGCGGATGAATTCGCCATCTCGCTCGCGGTTGACAAGAAGGCAAAGACGCTTTCG
GTCTCCGACAACGGCATCGGGATGAACCATGGTGACTTGCTCGACACGCTCGGCACCATCGCAAGGTCCGGCACCGGTGC
ATTTCTGGACGCGCTGAAATCCGAGGAAAAGGGCGACATCGGCTTGATCGGCCAGTTTGGTGTCGGGTTTTATTCCGCAT
TCATGGTGGCCGAGCGTGTGGATGTGCTGACGCGCAAAGCGGGTGAGGACGAAAGCTGGCTGTGGTCCTCAGACGGAAAG
GGCGAATTTTCGATCGAGCCCGGCGAGCGCGCCCAAAGCGGCACGACCGTCACGCTGCATTTGAAAAAGGACGCGAAGGA
ATTCCTCGAAGAGAGCCGCATTCGCCACATCATCAAGACCTATTCCGAACACATCAGCTTTCCGGTGCGGCTGGACACGG
AAGCGCTGAATTCCGCCTCCGCGATCTGGACCCGCGCGCCCAAAGAGATCACCGAGGAACAACACACAGAATTCTACCAC
CACGTCTCGAACGCCTTCGACAAGCCATGGCATGTCTTGCACAACCGCGTTGAGGGCACGGTCAATCACACGAGCCTGCT
TTATGTGCCTTCCATGGCGCCGTTTGATCTTTATGAGGCCGAGCGCAAGAGCCACGTGAAGCTCTATGTGAACCGGGTAT
TTATTTCCGACAACACACGCGATCTGATCCCCGCCTACCTGCGGTTTCTGCGCGGTGTGGTGGATTCGCAGGATCTGTCG
CTCAATGTCTCGCGCGAGATGCTGCAGTCGGATCCGAAACTGGCCAAGATCAAAACCTCTGTCACCAAGAAAGTGCTGAG
CGAGCTGAAGAAGAAGGCCAAAAAATCCCCCGAGGACTATGCAGGTTTCTGGCAGAATTTCGGTCCGGTCCTCAAGGAAG
GGCTGATCGAAGACCCCGCCCTGCGCGATCGCATCCTTGAAATCTGCCGCTTCTCGTCCACAAAATCCGGCGATGTGACC
AGCCTTGCCGACTACATCAGCCGCTGTAAGGAGGGTCAGGACGCGATCTATTACATCGCAGGCGATGACGCGAGAAAGAT
CGCGCAATCCCCGCATCTGGAAGGGTTCAGGGCCAAGGACGTCGAGGTGTTGCTGCTGTCTGATCATGTCGATGAATTCT
GGCTCCAGCACATCACGGAATTTGAAGGCAAGCCGTTCAAATCCATCACACGTGGGGCGGCTGATCTGGACAAGATCAAC
GAGGGTGAAAAAGCGGATGATGCCGAAGAGGAGGCGCAAGCACCCGATCTGAATGATCTGATTGCCGCGCTCAAACTGGA
ACTTGGCGCATCGGTCAAGGACGTGCGCCCCTCCAAAAGGTTGACGGATAGCCCCGTCTGTCTGATCGCGGATGAGGGTG
ACATCGACGTCAACCTTGAGAGAATGCTGAAACGGCATGGTCAGTTGCAGGACGCAATGCCACGGGTGCTTGAGTTGAAC
CCGGATCACAGGATCATCACGAAACTGGCTGAACGGGCGAAAGGCAGCGCAGCCGCGTCTGACACGTTGCTCAAGGATGC
CGCACATTTGCTGCTGGATCAGGCGCGCATTGCGGACGGCGAGACGCCCGCCGATCCGGCCGAATTTGTCCGGCGTCTGG
GCTCGGTGATGGACAGCGCGTTGTAA

Upstream 100 bases:

>100_bases
AATACTGCATCTGGACCGACAGGCGCTTGAAACGACAGTCGATTTTCTTATGTTCCTGCGCACGATCGGCCCCGACGCCA
CATGAAAAGAGGTTTTCACA

Downstream 100 bases:

>100_bases
AAGCGCGCGCAGGGAACTGTGCAGTAACAGGTGGTTTTAAAATGCAAACCGACTGGCGTTTGCCCGTCGGCCGGTTGTTC
ATGTGATCGGTTAGGTGCTG

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 621; Mature: 620

Protein sequence:

>621_residues
MTDASVKETFSFQTEVGQLLDIVAGSLYSNREIFLRELVSNASDACDKLRYEALTNPSLAQNADEFAISLAVDKKAKTLS
VSDNGIGMNHGDLLDTLGTIARSGTGAFLDALKSEEKGDIGLIGQFGVGFYSAFMVAERVDVLTRKAGEDESWLWSSDGK
GEFSIEPGERAQSGTTVTLHLKKDAKEFLEESRIRHIIKTYSEHISFPVRLDTEALNSASAIWTRAPKEITEEQHTEFYH
HVSNAFDKPWHVLHNRVEGTVNHTSLLYVPSMAPFDLYEAERKSHVKLYVNRVFISDNTRDLIPAYLRFLRGVVDSQDLS
LNVSREMLQSDPKLAKIKTSVTKKVLSELKKKAKKSPEDYAGFWQNFGPVLKEGLIEDPALRDRILEICRFSSTKSGDVT
SLADYISRCKEGQDAIYYIAGDDARKIAQSPHLEGFRAKDVEVLLLSDHVDEFWLQHITEFEGKPFKSITRGAADLDKIN
EGEKADDAEEEAQAPDLNDLIAALKLELGASVKDVRPSKRLTDSPVCLIADEGDIDVNLERMLKRHGQLQDAMPRVLELN
PDHRIITKLAERAKGSAAASDTLLKDAAHLLLDQARIADGETPADPAEFVRRLGSVMDSAL

Sequences:

>Translated_621_residues
MTDASVKETFSFQTEVGQLLDIVAGSLYSNREIFLRELVSNASDACDKLRYEALTNPSLAQNADEFAISLAVDKKAKTLS
VSDNGIGMNHGDLLDTLGTIARSGTGAFLDALKSEEKGDIGLIGQFGVGFYSAFMVAERVDVLTRKAGEDESWLWSSDGK
GEFSIEPGERAQSGTTVTLHLKKDAKEFLEESRIRHIIKTYSEHISFPVRLDTEALNSASAIWTRAPKEITEEQHTEFYH
HVSNAFDKPWHVLHNRVEGTVNHTSLLYVPSMAPFDLYEAERKSHVKLYVNRVFISDNTRDLIPAYLRFLRGVVDSQDLS
LNVSREMLQSDPKLAKIKTSVTKKVLSELKKKAKKSPEDYAGFWQNFGPVLKEGLIEDPALRDRILEICRFSSTKSGDVT
SLADYISRCKEGQDAIYYIAGDDARKIAQSPHLEGFRAKDVEVLLLSDHVDEFWLQHITEFEGKPFKSITRGAADLDKIN
EGEKADDAEEEAQAPDLNDLIAALKLELGASVKDVRPSKRLTDSPVCLIADEGDIDVNLERMLKRHGQLQDAMPRVLELN
PDHRIITKLAERAKGSAAASDTLLKDAAHLLLDQARIADGETPADPAEFVRRLGSVMDSAL
>Mature_620_residues
TDASVKETFSFQTEVGQLLDIVAGSLYSNREIFLRELVSNASDACDKLRYEALTNPSLAQNADEFAISLAVDKKAKTLSV
SDNGIGMNHGDLLDTLGTIARSGTGAFLDALKSEEKGDIGLIGQFGVGFYSAFMVAERVDVLTRKAGEDESWLWSSDGKG
EFSIEPGERAQSGTTVTLHLKKDAKEFLEESRIRHIIKTYSEHISFPVRLDTEALNSASAIWTRAPKEITEEQHTEFYHH
VSNAFDKPWHVLHNRVEGTVNHTSLLYVPSMAPFDLYEAERKSHVKLYVNRVFISDNTRDLIPAYLRFLRGVVDSQDLSL
NVSREMLQSDPKLAKIKTSVTKKVLSELKKKAKKSPEDYAGFWQNFGPVLKEGLIEDPALRDRILEICRFSSTKSGDVTS
LADYISRCKEGQDAIYYIAGDDARKIAQSPHLEGFRAKDVEVLLLSDHVDEFWLQHITEFEGKPFKSITRGAADLDKINE
GEKADDAEEEAQAPDLNDLIAALKLELGASVKDVRPSKRLTDSPVCLIADEGDIDVNLERMLKRHGQLQDAMPRVLELNP
DHRIITKLAERAKGSAAASDTLLKDAAHLLLDQARIADGETPADPAEFVRRLGSVMDSAL

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI155722983, Length=625, Percent_Identity=37.76, Blast_Score=402, Evalue=1e-112,
Organism=Homo sapiens, GI4507677, Length=684, Percent_Identity=35.0877192982456, Blast_Score=389, Evalue=1e-108,
Organism=Homo sapiens, GI154146191, Length=420, Percent_Identity=37.6190476190476, Blast_Score=260, Evalue=3e-69,
Organism=Homo sapiens, GI153792590, Length=420, Percent_Identity=37.6190476190476, Blast_Score=257, Evalue=2e-68,
Organism=Homo sapiens, GI20149594, Length=420, Percent_Identity=36.4285714285714, Blast_Score=255, Evalue=7e-68,
Organism=Escherichia coli, GI1786679, Length=630, Percent_Identity=44.6031746031746, Blast_Score=539, Evalue=1e-154,
Organism=Caenorhabditis elegans, GI17559162, Length=664, Percent_Identity=37.3493975903614, Blast_Score=439, Evalue=1e-123,
Organism=Caenorhabditis elegans, GI17542208, Length=679, Percent_Identity=36.0824742268041, Blast_Score=401, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI115535205, Length=643, Percent_Identity=33.5925349922239, Blast_Score=332, Evalue=3e-91,
Organism=Caenorhabditis elegans, GI115535167, Length=420, Percent_Identity=38.5714285714286, Blast_Score=289, Evalue=4e-78,
Organism=Saccharomyces cerevisiae, GI6323840, Length=680, Percent_Identity=36.3235294117647, Blast_Score=426, Evalue=1e-120,
Organism=Saccharomyces cerevisiae, GI6325016, Length=419, Percent_Identity=36.0381861575179, Blast_Score=264, Evalue=3e-71,
Organism=Drosophila melanogaster, GI21357739, Length=682, Percent_Identity=36.6568914956012, Blast_Score=404, Evalue=1e-113,
Organism=Drosophila melanogaster, GI24586016, Length=636, Percent_Identity=35.6918238993711, Blast_Score=361, Evalue=1e-100,
Organism=Drosophila melanogaster, GI17647529, Length=409, Percent_Identity=36.919315403423, Blast_Score=268, Evalue=1e-71,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_ROSDO (Q162C5)

Other databases:

- EMBL:   CP000362
- RefSeq:   YP_683854.1
- ProteinModelPortal:   Q162C5
- STRING:   Q162C5
- GeneID:   4195317
- GenomeReviews:   CP000362_GR
- KEGG:   rde:RD1_3696
- NMPDR:   fig|375451.6.peg.3437
- eggNOG:   COG0326
- HOGENOM:   HBG631012
- OMA:   AIYYITA
- PhylomeDB:   Q162C5
- ProtClustDB:   PRK05218
- BioCyc:   RDEN375451:RD1_3696-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 68991; Mature: 68860

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDASVKETFSFQTEVGQLLDIVAGSLYSNREIFLRELVSNASDACDKLRYEALTNPSLA
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
QNADEFAISLAVDKKAKTLSVSDNGIGMNHGDLLDTLGTIARSGTGAFLDALKSEEKGDI
CCHHHHEEEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCE
GLIGQFGVGFYSAFMVAERVDVLTRKAGEDESWLWSSDGKGEFSIEPGERAQSGTTVTLH
EEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCEEECCCCCCCCCCEEEEE
LKKDAKEFLEESRIRHIIKTYSEHISFPVRLDTEALNSASAIWTRAPKEITEEQHTEFYH
EHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHCCHHHHHHCCCHHHHHHHHHHHHH
HVSNAFDKPWHVLHNRVEGTVNHTSLLYVPSMAPFDLYEAERKSHVKLYVNRVFISDNTR
HHHHHCCCCHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHCCEEEEEEEEEECCCCH
DLIPAYLRFLRGVVDSQDLSLNVSREMLQSDPKLAKIKTSVTKKVLSELKKKAKKSPEDY
HHHHHHHHHHHHHCCCCCCEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHH
AGFWQNFGPVLKEGLIEDPALRDRILEICRFSSTKSGDVTSLADYISRCKEGQDAIYYIA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCEEEEEE
GDDARKIAQSPHLEGFRAKDVEVLLLSDHVDEFWLQHITEFEGKPFKSITRGAADLDKIN
CCHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHCC
EGEKADDAEEEAQAPDLNDLIAALKLELGASVKDVRPSKRLTDSPVCLIADEGDIDVNLE
CCCCCCCCHHHHCCCCHHHHHHHHHHHHCCCHHHCCCCCCCCCCCEEEEECCCCCCCCHH
RMLKRHGQLQDAMPRVLELNPDHRIITKLAERAKGSAAASDTLLKDAAHLLLDQARIADG
HHHHHCCCHHHHCCHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC
ETPADPAEFVRRLGSVMDSAL
CCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDASVKETFSFQTEVGQLLDIVAGSLYSNREIFLRELVSNASDACDKLRYEALTNPSLA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
QNADEFAISLAVDKKAKTLSVSDNGIGMNHGDLLDTLGTIARSGTGAFLDALKSEEKGDI
CCHHHHEEEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCE
GLIGQFGVGFYSAFMVAERVDVLTRKAGEDESWLWSSDGKGEFSIEPGERAQSGTTVTLH
EEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCEEECCCCCCCCCCEEEEE
LKKDAKEFLEESRIRHIIKTYSEHISFPVRLDTEALNSASAIWTRAPKEITEEQHTEFYH
EHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHCCHHHHHHCCCHHHHHHHHHHHHH
HVSNAFDKPWHVLHNRVEGTVNHTSLLYVPSMAPFDLYEAERKSHVKLYVNRVFISDNTR
HHHHHCCCCHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHCCEEEEEEEEEECCCCH
DLIPAYLRFLRGVVDSQDLSLNVSREMLQSDPKLAKIKTSVTKKVLSELKKKAKKSPEDY
HHHHHHHHHHHHHCCCCCCEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHH
AGFWQNFGPVLKEGLIEDPALRDRILEICRFSSTKSGDVTSLADYISRCKEGQDAIYYIA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCEEEEEE
GDDARKIAQSPHLEGFRAKDVEVLLLSDHVDEFWLQHITEFEGKPFKSITRGAADLDKIN
CCHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHCC
EGEKADDAEEEAQAPDLNDLIAALKLELGASVKDVRPSKRLTDSPVCLIADEGDIDVNLE
CCCCCCCCHHHHCCCCHHHHHHHHHHHHCCCHHHCCCCCCCCCCCEEEEECCCCCCCCHH
RMLKRHGQLQDAMPRVLELNPDHRIITKLAERAKGSAAASDTLLKDAAHLLLDQARIADG
HHHHHCCCHHHHCCHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC
ETPADPAEFVRRLGSVMDSAL
CCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA