Click here to switch to the map view.

The map label for this gene is hutU [H]

Identifier: 110680834

GI number: 110680834

Start: 3549338

End: 3551008

Strand: Direct

Name: hutU [H]

Synonym: RD1_3682

Alternate gene names: 110680834

Gene position: 3549338-3551008 (Clockwise)

Preceding gene: 110680833

Following gene: 110680835

Centisome position: 85.88

GC content: 62.18

Gene sequence:

>1671_bases
ATGACCAACGCCCGTCATAACCTGCGCGACATCTACCCCCCTACCGGGCCGGACATCACGGCCAAAAGCTGGCTCACCGA
GGCGCCCATGCGCATGCTGATGAACAACCTGCACCCGGATGTAGCCGAGAACCCGCATGAGTTGGTGGTTTACGGCGGCA
TCGGGCGTGCCGCGCGCACGTGGGAAGATTTCGATGCGATTGTCGCCGCGCTGAAAGACCTTGAGGAGACGCAAACGCTG
CTGGTGCAGTCGGGCAAACCGGTGGGCGTGTTCAACACGCATAAGGATGCACCGCGTGTGCTGATCGCCAATTCGAACCT
CGTGCCGCATTGGGCCACGTGGGAACATTTCAACGAGCTCGATAAAAAGGGCCTTGCGATGTATGGCCAGATGACCGCCG
GGTCGTGGATTTACATCGGCACACAAGGGATCGTGCAGGGCACCTACGAGACCTTCATGGAAGCGGGTCGCCAGCATTAT
GATGGCAACCTCAAAGGCCGCTGGATCCTGACCGGCGGTCTGGGCGGCATGGGTGGTGCACAACCGCTGGCGGCGGTCAT
GGCCGGGGCCTGCTGCCTCGCGGTGGAATGCGACGAGACCCGCGCCGATTTCCGTCTGCGCACCCGCTATGTCGATGAAA
AAACCCATGATCTGGACGAAGCGCTGGCGATGATCGAGCGCTGGACGGCGGCGGGTGAAGCCAAATCCGTAGCCCTGATC
GGCAATGCGGCTGATGTGTTTCCAGAATTGGTCAAGCGTGGCGTGAAACCTGATATGGTCACCGACCAGACCTCTGCCCA
CGACCCCATTCACGGCTATCTGCCGCAAGGCTGGAGCGTCGCGCAGTGGCGTGAAAAGCAGGAAAGCGATACCAAGGCAG
TTGAGGCAGCCGCGCGCGCCAGCATGAAGACACAGGTCGCCGCGATGGTCGATTTCTGGAATCAGGGCGTGCCCACGCTG
GATTACGGCAACAACATCCGGCAGGTCGCACAAGAGGAAGGGCTGGAAAACGCCTTTGCCTTCCCCGGCTTCGTGCCCGC
CTATATCCGCCCGCTGTTCTGCCGGGGCATCGGCCCGTTCCGCTGGTGCGCGCTGTCGGGCGACCCCGAGGACATCTACA
AGACAGATGCCAAGGTCAAGGAGTTGATCGACGACCCGCATCTGCACAACTGGCTGGACATGGCCCGCGAGCGGATCGCG
TTTCAGGGCCTGCCCGCGCGCATTTGCTGGGTAGGACTGGGCCTGCGTGACAAGCTGGGTCTTGCGTTCAACGAAATGGT
GCGCACTGGCGAACTGAGCGCTCCGGTCGTCATCGGTCGCGACCATCTGGACTCTGGTTCTGTGGCCTCGCCCAACCGCG
AAACAGAGGCGATGAAAGACGGCTCGGACGCGGTGTCGGACTGGCCGCTCTTGAATGCGATGCTCAACGTGGCAGGCGGT
GCGACATGGGTATCGCTGCACCACGGGGGCGGTGTCGGCATGGGCTTTTCGCAGCACTCGGGCATGGTCATTTGCTGTGA
CGGGACCGAGGATGCAGACCGCCGCATTGCGAATGTCCTGTGGAATGACCCGGCGACAGGGGTGATGCGTCACGCCGATG
CAGGCTATGATGTCGCCCTTGATTGCGCGCGCGAGAATGGCTTGAACCTGCCCGGTATCCTGGGCCGCTGA

Upstream 100 bases:

>100_bases
TGACCCGCGATCTGCGCATCATGCGCATCTACGAAGGGTCCTCTGAAATTCAACGCAATATCATCGCCGGCCACCTGCTG
GCGCACTGAAGGAGAAAACC

Downstream 100 bases:

>100_bases
ACAAAAGGAACACGCAGATGTTTTTGAAAAATGCTTGGTATGTCGCCGCTTGGGATCATGAGATCACGCGCGAATTGCAA
CAGATTACGGTGCTTGGTGA

Product: urocanate hydratase

Products: NA

Alternate protein names: Urocanase; Imidazolonepropionate hydrolase [H]

Number of amino acids: Translated: 556; Mature: 555

Protein sequence:

>556_residues
MTNARHNLRDIYPPTGPDITAKSWLTEAPMRMLMNNLHPDVAENPHELVVYGGIGRAARTWEDFDAIVAALKDLEETQTL
LVQSGKPVGVFNTHKDAPRVLIANSNLVPHWATWEHFNELDKKGLAMYGQMTAGSWIYIGTQGIVQGTYETFMEAGRQHY
DGNLKGRWILTGGLGGMGGAQPLAAVMAGACCLAVECDETRADFRLRTRYVDEKTHDLDEALAMIERWTAAGEAKSVALI
GNAADVFPELVKRGVKPDMVTDQTSAHDPIHGYLPQGWSVAQWREKQESDTKAVEAAARASMKTQVAAMVDFWNQGVPTL
DYGNNIRQVAQEEGLENAFAFPGFVPAYIRPLFCRGIGPFRWCALSGDPEDIYKTDAKVKELIDDPHLHNWLDMARERIA
FQGLPARICWVGLGLRDKLGLAFNEMVRTGELSAPVVIGRDHLDSGSVASPNRETEAMKDGSDAVSDWPLLNAMLNVAGG
ATWVSLHHGGGVGMGFSQHSGMVICCDGTEDADRRIANVLWNDPATGVMRHADAGYDVALDCARENGLNLPGILGR

Sequences:

>Translated_556_residues
MTNARHNLRDIYPPTGPDITAKSWLTEAPMRMLMNNLHPDVAENPHELVVYGGIGRAARTWEDFDAIVAALKDLEETQTL
LVQSGKPVGVFNTHKDAPRVLIANSNLVPHWATWEHFNELDKKGLAMYGQMTAGSWIYIGTQGIVQGTYETFMEAGRQHY
DGNLKGRWILTGGLGGMGGAQPLAAVMAGACCLAVECDETRADFRLRTRYVDEKTHDLDEALAMIERWTAAGEAKSVALI
GNAADVFPELVKRGVKPDMVTDQTSAHDPIHGYLPQGWSVAQWREKQESDTKAVEAAARASMKTQVAAMVDFWNQGVPTL
DYGNNIRQVAQEEGLENAFAFPGFVPAYIRPLFCRGIGPFRWCALSGDPEDIYKTDAKVKELIDDPHLHNWLDMARERIA
FQGLPARICWVGLGLRDKLGLAFNEMVRTGELSAPVVIGRDHLDSGSVASPNRETEAMKDGSDAVSDWPLLNAMLNVAGG
ATWVSLHHGGGVGMGFSQHSGMVICCDGTEDADRRIANVLWNDPATGVMRHADAGYDVALDCARENGLNLPGILGR
>Mature_555_residues
TNARHNLRDIYPPTGPDITAKSWLTEAPMRMLMNNLHPDVAENPHELVVYGGIGRAARTWEDFDAIVAALKDLEETQTLL
VQSGKPVGVFNTHKDAPRVLIANSNLVPHWATWEHFNELDKKGLAMYGQMTAGSWIYIGTQGIVQGTYETFMEAGRQHYD
GNLKGRWILTGGLGGMGGAQPLAAVMAGACCLAVECDETRADFRLRTRYVDEKTHDLDEALAMIERWTAAGEAKSVALIG
NAADVFPELVKRGVKPDMVTDQTSAHDPIHGYLPQGWSVAQWREKQESDTKAVEAAARASMKTQVAAMVDFWNQGVPTLD
YGNNIRQVAQEEGLENAFAFPGFVPAYIRPLFCRGIGPFRWCALSGDPEDIYKTDAKVKELIDDPHLHNWLDMARERIAF
QGLPARICWVGLGLRDKLGLAFNEMVRTGELSAPVVIGRDHLDSGSVASPNRETEAMKDGSDAVSDWPLLNAMLNVAGGA
TWVSLHHGGGVGMGFSQHSGMVICCDGTEDADRRIANVLWNDPATGVMRHADAGYDVALDCARENGLNLPGILGR

Specific function: Unknown

COG id: COG2987

COG function: function code E; Urocanate hydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the urocanase family [H]

Homologues:

Organism=Homo sapiens, GI21389467, Length=574, Percent_Identity=33.1010452961672, Blast_Score=290, Evalue=2e-78,
Organism=Homo sapiens, GI260306182, Length=217, Percent_Identity=39.63133640553, Blast_Score=157, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI71997891, Length=551, Percent_Identity=34.8457350272232, Blast_Score=313, Evalue=2e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000193 [H]

Pfam domain/function: PF01175 Urocanase [H]

EC number: =4.2.1.49 [H]

Molecular weight: Translated: 60801; Mature: 60670

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS01233 UROCANASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNARHNLRDIYPPTGPDITAKSWLTEAPMRMLMNNLHPDVAENPHELVVYGGIGRAART
CCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHH
WEDFDAIVAALKDLEETQTLLVQSGKPVGVFNTHKDAPRVLIANSNLVPHWATWEHFNEL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCEEEEECCCCCCCCCCHHHHHHH
DKKGLAMYGQMTAGSWIYIGTQGIVQGTYETFMEAGRQHYDGNLKGRWILTGGLGGMGGA
HHCCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCH
QPLAAVMAGACCLAVECDETRADFRLRTRYVDEKTHDLDEALAMIERWTAAGEAKSVALI
HHHHHHHHCCEEEEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEE
GNAADVFPELVKRGVKPDMVTDQTSAHDPIHGYLPQGWSVAQWREKQESDTKAVEAAARA
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
SMKTQVAAMVDFWNQGVPTLDYGNNIRQVAQEEGLENAFAFPGFVPAYIRPLFCRGIGPF
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHCCCCCC
RWCALSGDPEDIYKTDAKVKELIDDPHLHNWLDMARERIAFQGLPARICWVGLGLRDKLG
EEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHH
LAFNEMVRTGELSAPVVIGRDHLDSGSVASPNRETEAMKDGSDAVSDWPLLNAMLNVAGG
HHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHCCC
ATWVSLHHGGGVGMGFSQHSGMVICCDGTEDADRRIANVLWNDPATGVMRHADAGYDVAL
EEEEEEECCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCHHHHHHCCCCCCEEE
DCARENGLNLPGILGR
EEHHCCCCCCCCCCCC
>Mature Secondary Structure 
TNARHNLRDIYPPTGPDITAKSWLTEAPMRMLMNNLHPDVAENPHELVVYGGIGRAART
CCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHH
WEDFDAIVAALKDLEETQTLLVQSGKPVGVFNTHKDAPRVLIANSNLVPHWATWEHFNEL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCEEEEECCCCCCCCCCHHHHHHH
DKKGLAMYGQMTAGSWIYIGTQGIVQGTYETFMEAGRQHYDGNLKGRWILTGGLGGMGGA
HHCCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCH
QPLAAVMAGACCLAVECDETRADFRLRTRYVDEKTHDLDEALAMIERWTAAGEAKSVALI
HHHHHHHHCCEEEEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEE
GNAADVFPELVKRGVKPDMVTDQTSAHDPIHGYLPQGWSVAQWREKQESDTKAVEAAARA
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
SMKTQVAAMVDFWNQGVPTLDYGNNIRQVAQEEGLENAFAFPGFVPAYIRPLFCRGIGPF
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHCCCCCC
RWCALSGDPEDIYKTDAKVKELIDDPHLHNWLDMARERIAFQGLPARICWVGLGLRDKLG
EEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHH
LAFNEMVRTGELSAPVVIGRDHLDSGSVASPNRETEAMKDGSDAVSDWPLLNAMLNVAGG
HHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHCCC
ATWVSLHHGGGVGMGFSQHSGMVICCDGTEDADRRIANVLWNDPATGVMRHADAGYDVAL
EEEEEEECCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCHHHHHHCCCCCCEEE
DCARENGLNLPGILGR
EEHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA