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The map label for this gene is aspC [H]

Identifier: 110680370

GI number: 110680370

Start: 3052918

End: 3054108

Strand: Direct

Name: aspC [H]

Synonym: RD1_3185

Alternate gene names: 110680370

Gene position: 3052918-3054108 (Clockwise)

Preceding gene: 110680369

Following gene: 110680372

Centisome position: 73.87

GC content: 65.41

Gene sequence:

>1191_bases
ATGCAACTCTCCGAGCGGATCATGGGCATCACGGGCGGCGGCTCAGACGGCTGGGACGTATTCCTGAAGGCACGGCGGAT
GATCGCGCAAGGGGTCGCGGTCACGGAGCTGACCATTGGCGAGCATGACATCCGCACCGCAGCCCCCGTTCTGCAAGAGA
TGCACCGCACAGCGCTGGCGGGACATACCGGATATGCTGCCGTGCCCGGCACCGATGCGCTGCGCGATCGTGTTGCCGCG
CGGGTGCACGCGCGCACCGGTGTTGAGACGCACCGCGAGAATGTGCTGATCACGCCCGGCGGTCAGGCGGCGCTGTTTGC
GGCCCATACGGCGGTCTGTGATCCCGGGGATATGGCACTTTATATTGACCCCTATTATGCCACTTATCCGGGGACGCTGC
GCGGTGCGGGGGCGGTGCCACAGGCCATCGGCGCGCGCGCGGAAAACGCCTTTCAGCCGCGCGTTGAGGATATCGCACCC
CATGCGGGCAAGGCGCAGTCGCTGTTGATCAACACGCCCAATAATCCCACCGGTGTGGTCTATGGGCGTGACACATTGCA
GGGGATCGCCGATCTGTGCATCGCAGAGGATATGTGGCTGATTTCGGATGAGGTTTATGACACGCAGGTCTGGGAAGGCA
CCCATCTGAGCCCGCGCGCCCTGCCCGGCATGGCCGGGCGGACCCTGGTGGTCGGGTCGATGTCGAAATCCCATGCGATG
ACCGGGTCGCGCTGCGGCTGGATCATCGGCCCCGAAGAGGCGATTGCGCATCTCACGAATCTGGCGACCCATACGACCTA
TGGTGTGCCGGGGTTCATTCAGGACGCCGCCTGCTTTGCGCTGGCGCAGGGCGATGCCTTTGAGGAAGAGGTTGCCGCCC
CGTTCCGGCGGCGCCGCGCGCTGGCGCAGCAGATCCTTGCGGGGCAGGATGTCGTGGGCCTCGTCCCGGCGCAGGGGGCG
ATGTATCTGATGCTGGATATGCGCGCCACGGGGATGACCGGCGAGGCGTTTGCCAATGACCTGCTGGACGCCCATCATAT
CGCCGTCATGCCCGGAGAGAGCTTTGGCGGCTGCGCCCCGGGACATATCCGGGTCGCGATGACAGTGGCGGATGATGTCT
TTGCCAAGGCGCTGCAAACGGTACTGGATCATGCGGTGGCGCGTTGCACCGCGCGGGCAGCGGCGCAGTAG

Upstream 100 bases:

>100_bases
CATGGGGCAGACCTACGCCGTTGTGGCGCGTGGCGTCAAGGGCGATTGACGAATCAGGTGCCCTCTGGCCTCTGTGCGGC
GCAGCAGCAAAGGACAGATC

Downstream 100 bases:

>100_bases
ACCCGACACCGGCGTAAAAGCGTCATGCGAGGAACTGACTCACGTAACGCTGCCTGACATCAGAGATTTCAACGCGTTAC
GTGATACGTGATATCTCAGG

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MQLSERIMGITGGGSDGWDVFLKARRMIAQGVAVTELTIGEHDIRTAAPVLQEMHRTALAGHTGYAAVPGTDALRDRVAA
RVHARTGVETHRENVLITPGGQAALFAAHTAVCDPGDMALYIDPYYATYPGTLRGAGAVPQAIGARAENAFQPRVEDIAP
HAGKAQSLLINTPNNPTGVVYGRDTLQGIADLCIAEDMWLISDEVYDTQVWEGTHLSPRALPGMAGRTLVVGSMSKSHAM
TGSRCGWIIGPEEAIAHLTNLATHTTYGVPGFIQDAACFALAQGDAFEEEVAAPFRRRRALAQQILAGQDVVGLVPAQGA
MYLMLDMRATGMTGEAFANDLLDAHHIAVMPGESFGGCAPGHIRVAMTVADDVFAKALQTVLDHAVARCTARAAAQ

Sequences:

>Translated_396_residues
MQLSERIMGITGGGSDGWDVFLKARRMIAQGVAVTELTIGEHDIRTAAPVLQEMHRTALAGHTGYAAVPGTDALRDRVAA
RVHARTGVETHRENVLITPGGQAALFAAHTAVCDPGDMALYIDPYYATYPGTLRGAGAVPQAIGARAENAFQPRVEDIAP
HAGKAQSLLINTPNNPTGVVYGRDTLQGIADLCIAEDMWLISDEVYDTQVWEGTHLSPRALPGMAGRTLVVGSMSKSHAM
TGSRCGWIIGPEEAIAHLTNLATHTTYGVPGFIQDAACFALAQGDAFEEEVAAPFRRRRALAQQILAGQDVVGLVPAQGA
MYLMLDMRATGMTGEAFANDLLDAHHIAVMPGESFGGCAPGHIRVAMTVADDVFAKALQTVLDHAVARCTARAAAQ
>Mature_396_residues
MQLSERIMGITGGGSDGWDVFLKARRMIAQGVAVTELTIGEHDIRTAAPVLQEMHRTALAGHTGYAAVPGTDALRDRVAA
RVHARTGVETHRENVLITPGGQAALFAAHTAVCDPGDMALYIDPYYATYPGTLRGAGAVPQAIGARAENAFQPRVEDIAP
HAGKAQSLLINTPNNPTGVVYGRDTLQGIADLCIAEDMWLISDEVYDTQVWEGTHLSPRALPGMAGRTLVVGSMSKSHAM
TGSRCGWIIGPEEAIAHLTNLATHTTYGVPGFIQDAACFALAQGDAFEEEVAAPFRRRRALAQQILAGQDVVGLVPAQGA
MYLMLDMRATGMTGEAFANDLLDAHHIAVMPGESFGGCAPGHIRVAMTVADDVFAKALQTVLDHAVARCTARAAAQ

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=282, Percent_Identity=32.6241134751773, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI56713256, Length=282, Percent_Identity=32.6241134751773, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI95147551, Length=260, Percent_Identity=32.3076923076923, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI169881279, Length=260, Percent_Identity=32.3076923076923, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI169881281, Length=236, Percent_Identity=29.6610169491525, Blast_Score=102, Evalue=8e-22,
Organism=Escherichia coli, GI1786816, Length=329, Percent_Identity=24.9240121580547, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1788722, Length=368, Percent_Identity=23.9130434782609, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1788627, Length=382, Percent_Identity=23.0366492146597, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790797, Length=269, Percent_Identity=26.3940520446097, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17567369, Length=199, Percent_Identity=31.1557788944724, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71994472, Length=255, Percent_Identity=27.843137254902, Blast_Score=104, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI71994476, Length=255, Percent_Identity=27.843137254902, Blast_Score=104, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6322401, Length=228, Percent_Identity=25.4385964912281, Blast_Score=80, Evalue=5e-16,
Organism=Drosophila melanogaster, GI28573069, Length=249, Percent_Identity=28.9156626506024, Blast_Score=114, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24646114, Length=249, Percent_Identity=28.9156626506024, Blast_Score=114, Evalue=8e-26,
Organism=Drosophila melanogaster, GI28573067, Length=249, Percent_Identity=28.9156626506024, Blast_Score=114, Evalue=8e-26,
Organism=Drosophila melanogaster, GI28573065, Length=249, Percent_Identity=28.9156626506024, Blast_Score=114, Evalue=8e-26,
Organism=Drosophila melanogaster, GI18859735, Length=367, Percent_Identity=23.7057220708447, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 41853; Mature: 41853

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLSERIMGITGGGSDGWDVFLKARRMIAQGVAVTELTIGEHDIRTAAPVLQEMHRTALA
CCCHHCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHC
GHTGYAAVPGTDALRDRVAARVHARTGVETHRENVLITPGGQAALFAAHTAVCDPGDMAL
CCCCCEECCCCHHHHHHHHHHHHHHCCCHHHCCCEEECCCCCEEEEEHHHHCCCCCCEEE
YIDPYYATYPGTLRGAGAVPQAIGARAENAFQPRVEDIAPHAGKAQSLLINTPNNPTGVV
EECCCEECCCCCCCCCCCCHHHHCCCCCCCCCCCHHHHCCCCCCCCEEEEECCCCCCEEE
YGRDTLQGIADLCIAEDMWLISDEVYDTQVWEGTHLSPRALPGMAGRTLVVGSMSKSHAM
EECHHHHHHHHHHHHCCCCEECCCCCCCEECCCCCCCCCCCCCCCCCEEEEECCCHHHCC
TGSRCGWIIGPEEAIAHLTNLATHTTYGVPGFIQDAACFALAQGDAFEEEVAAPFRRRRA
CCCCCCEEECHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LAQQILAGQDVVGLVPAQGAMYLMLDMRATGMTGEAFANDLLDAHHIAVMPGESFGGCAP
HHHHHHCCCCEEEEECCCCCEEEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCC
GHIRVAMTVADDVFAKALQTVLDHAVARCTARAAAQ
CCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQLSERIMGITGGGSDGWDVFLKARRMIAQGVAVTELTIGEHDIRTAAPVLQEMHRTALA
CCCHHCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHC
GHTGYAAVPGTDALRDRVAARVHARTGVETHRENVLITPGGQAALFAAHTAVCDPGDMAL
CCCCCEECCCCHHHHHHHHHHHHHHCCCHHHCCCEEECCCCCEEEEEHHHHCCCCCCEEE
YIDPYYATYPGTLRGAGAVPQAIGARAENAFQPRVEDIAPHAGKAQSLLINTPNNPTGVV
EECCCEECCCCCCCCCCCCHHHHCCCCCCCCCCCHHHHCCCCCCCCEEEEECCCCCCEEE
YGRDTLQGIADLCIAEDMWLISDEVYDTQVWEGTHLSPRALPGMAGRTLVVGSMSKSHAM
EECHHHHHHHHHHHHCCCCEECCCCCCCEECCCCCCCCCCCCCCCCCEEEEECCCHHHCC
TGSRCGWIIGPEEAIAHLTNLATHTTYGVPGFIQDAACFALAQGDAFEEEVAAPFRRRRA
CCCCCCEEECHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LAQQILAGQDVVGLVPAQGAMYLMLDMRATGMTGEAFANDLLDAHHIAVMPGESFGGCAP
HHHHHHCCCCEEEEECCCCCEEEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCC
GHIRVAMTVADDVFAKALQTVLDHAVARCTARAAAQ
CCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]