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The map label for this gene is erpA [H]

Identifier: 110680354

GI number: 110680354

Start: 3040159

End: 3040482

Strand: Direct

Name: erpA [H]

Synonym: RD1_3168

Alternate gene names: 110680354

Gene position: 3040159-3040482 (Clockwise)

Preceding gene: 110680346

Following gene: 110680357

Centisome position: 73.56

GC content: 56.48

Gene sequence:

>324_bases
ATGCAACTTCCACCCAAAGTCACCCCGCGCGCTTTTGAACGACTCGCAGAGATCGGTGCATCTGATGACGGTAAGGCCCT
GCGCGTTGCGGTTGAGGGCGGGGGATGTTCAGGGTTTCAATACGAGATCGATCTGGACGAGCCAAAGGAGGACGACCTCG
TTCTGGAAGGTGCCGGGCAAAAAGTGGTGATCGACACGGTGTCGCTGCCGTTTCTGGCAGACGCTGTCATCGACTTTACC
GAAGAGTTGATCGGCGCACGTTTTGTCATCAACAATCCGAACGCCTCCAGTTCCTGCGGCTGTGGGACGTCATTCTCGAT
GTAG

Upstream 100 bases:

>100_bases
AGGCATAGGGTGCTGTCATGTCGCCGGTCCTTGTCGCCTGTCATGAGAAGTTATATATTCATCCCAACAGATTAATAAAC
CCGTTTGACGGAGTACTGCG

Downstream 100 bases:

>100_bases
GATGAGCATCGCACTTTAGCGTTCTGTTTTAAAAAACTAATTCGATCTGGAGAACCGTTCGAAAAAACGGTCGAAATGCG
GGCAGGACTGCGCTGCCCCC

Product: FeS cluster assembly HesB family protein, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 107; Mature: 107

Protein sequence:

>107_residues
MQLPPKVTPRAFERLAEIGASDDGKALRVAVEGGGCSGFQYEIDLDEPKEDDLVLEGAGQKVVIDTVSLPFLADAVIDFT
EELIGARFVINNPNASSSCGCGTSFSM

Sequences:

>Translated_107_residues
MQLPPKVTPRAFERLAEIGASDDGKALRVAVEGGGCSGFQYEIDLDEPKEDDLVLEGAGQKVVIDTVSLPFLADAVIDFT
EELIGARFVINNPNASSSCGCGTSFSM
>Mature_107_residues
MQLPPKVTPRAFERLAEIGASDDGKALRVAVEGGGCSGFQYEIDLDEPKEDDLVLEGAGQKVVIDTVSLPFLADAVIDFT
EELIGARFVINNPNASSSCGCGTSFSM

Specific function: Required for insertion of 4Fe-4S clusters for at least ispG [H]

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI160420328, Length=104, Percent_Identity=47.1153846153846, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1786351, Length=108, Percent_Identity=43.5185185185185, Blast_Score=93, Evalue=3e-21,
Organism=Escherichia coli, GI1788877, Length=85, Percent_Identity=43.5294117647059, Blast_Score=71, Evalue=1e-14,
Organism=Escherichia coli, GI1787974, Length=103, Percent_Identity=35.9223300970874, Blast_Score=71, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71998452, Length=105, Percent_Identity=45.7142857142857, Blast_Score=92, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6325324, Length=124, Percent_Identity=35.4838709677419, Blast_Score=74, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6323001, Length=100, Percent_Identity=35, Blast_Score=74, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24649697, Length=108, Percent_Identity=50, Blast_Score=95, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24642263, Length=104, Percent_Identity=37.5, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 11310; Mature: 11310

Theoretical pI: Translated: 3.93; Mature: 3.93

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLPPKVTPRAFERLAEIGASDDGKALRVAVEGGGCSGFQYEIDLDEPKEDDLVLEGAGQ
CCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCEEEEEECCCCCCCCEEEECCCC
KVVIDTVSLPFLADAVIDFTEELIGARFVINNPNASSSCGCGTSFSM
EEEEEECCCCHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQLPPKVTPRAFERLAEIGASDDGKALRVAVEGGGCSGFQYEIDLDEPKEDDLVLEGAGQ
CCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCEEEEEECCCCCCCCEEEECCCC
KVVIDTVSLPFLADAVIDFTEELIGARFVINNPNASSSCGCGTSFSM
EEEEEECCCCHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA