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The map label for this gene is fur [H]

Identifier: 110680327

GI number: 110680327

Start: 3015936

End: 3016349

Strand: Direct

Name: fur [H]

Synonym: RD1_3140

Alternate gene names: 110680327

Gene position: 3015936-3016349 (Clockwise)

Preceding gene: 110680326

Following gene: 110680328

Centisome position: 72.97

GC content: 57.49

Gene sequence:

>414_bases
ATGAGCAAACCAATCATCAAACGCTGCGAGGCGAAGGGGCTGCGCATGACCGGCCAGAGGCGTGTCATCGCGCAGGTCCT
CGAAGACAGCGCGGATCACCCGGATGTCGAGGAGCTTTATGCGCGTGCCGTGACCATCGACGGCGGCATTTCCATCGCGA
CGGTGTACCGAACGGTCAAGCTTTTCGAGGAAGCGGGCATTCTGGACAAGCTCGAATTCGGCGACGGGCGCGCGCGCTAC
GAGGACGCCGAACGCGACCATCATGATCATCTGATTGATATGAATTCAGGCGAGGTTATTGAATTCGTAGACGCCGAAAT
CGAAGCCTTGCAGGAGCGGATCGCCAACAAGCTGGGATATGAGTTACGCGGGCACCGTCTGGAACTCTATGGTGTGCCGC
TGAAAAAAGAGTGA

Upstream 100 bases:

>100_bases
GCGCCTTGCTGGTGCAGAAGTCAACCGAAACACAAAAACTTGGCTGGAACCCCTGCGCAAAGGCGGCTAAAAACTCGGCC
TACGTCACGGGGGCCATCGC

Downstream 100 bases:

>100_bases
TGCAAGCGCGCGGCGTGGACATCTGCAACGGCGCGGCCTAAGGGACTGGCATCCCTTTTGGCAGGAAAACCCCCGATGGA
TAATTTGCGCGGCGCGGCCC

Product: ferric uptake regulation protein, putative

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 137; Mature: 136

Protein sequence:

>137_residues
MSKPIIKRCEAKGLRMTGQRRVIAQVLEDSADHPDVEELYARAVTIDGGISIATVYRTVKLFEEAGILDKLEFGDGRARY
EDAERDHHDHLIDMNSGEVIEFVDAEIEALQERIANKLGYELRGHRLELYGVPLKKE

Sequences:

>Translated_137_residues
MSKPIIKRCEAKGLRMTGQRRVIAQVLEDSADHPDVEELYARAVTIDGGISIATVYRTVKLFEEAGILDKLEFGDGRARY
EDAERDHHDHLIDMNSGEVIEFVDAEIEALQERIANKLGYELRGHRLELYGVPLKKE
>Mature_136_residues
SKPIIKRCEAKGLRMTGQRRVIAQVLEDSADHPDVEELYARAVTIDGGISIATVYRTVKLFEEAGILDKLEFGDGRARYE
DAERDHHDHLIDMNSGEVIEFVDAEIEALQERIANKLGYELRGHRLELYGVPLKKE

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=120, Percent_Identity=42.5, Blast_Score=92, Evalue=2e-20,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 15564; Mature: 15433

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPIIKRCEAKGLRMTGQRRVIAQVLEDSADHPDVEELYARAVTIDGGISIATVYRTVK
CCCHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHH
LFEEAGILDKLEFGDGRARYEDAERDHHDHLIDMNSGEVIEFVDAEIEALQERIANKLGY
HHHHCCCCCEECCCCCCCCCCCCCCCCCCCEEECCCCCEEHHHHHHHHHHHHHHHHHHCH
ELRGHRLELYGVPLKKE
HHCCCEEEEECCCCCCC
>Mature Secondary Structure 
SKPIIKRCEAKGLRMTGQRRVIAQVLEDSADHPDVEELYARAVTIDGGISIATVYRTVK
CCHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHH
LFEEAGILDKLEFGDGRARYEDAERDHHDHLIDMNSGEVIEFVDAEIEALQERIANKLGY
HHHHCCCCCEECCCCCCCCCCCCCCCCCCCEEECCCCCEEHHHHHHHHHHHHHHHHHHCH
ELRGHRLELYGVPLKKE
HHCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9835040 [H]