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The map label for this gene is fabD [H]

Identifier: 110680232

GI number: 110680232

Start: 2910347

End: 2911279

Strand: Reverse

Name: fabD [H]

Synonym: RD1_3040

Alternate gene names: 110680232

Gene position: 2911279-2910347 (Counterclockwise)

Preceding gene: 110680234

Following gene: 110680231

Centisome position: 70.44

GC content: 62.92

Gene sequence:

>933_bases
ATGAGCATTGCATTTGTTTTCCCCGGACAGGGCGCGCAGACGGTTGGCATGGGGCGGGCACTGGCCGAAGCCTACCCGGA
CGCGCAGGCCGTGTTTGATGAGGTGGATGATGCCTTGGGCGAAAAGCTGAGCGCGTTGATCTGGGAGGGCGATATCGAAA
CGCTGACGCTGACGCAGAATGCGCAACCAGCGTTGATGGCTACGTCCATGGCCGCGATCCGTGCGCTGGCTGCTGAGGGC
GTGGGTATGGAGCGCCTTTCATTCGTGGCGGGTCACAGCCTTGGGGAATATTCCGCTTTGGCCGCTGCGGGGACGTTCTC
GATTGCGGATACGGCGCGGTTGTTGCGCACACGCGGGCTGGCGATGCAGCGTGCGGTGCCCGTTGGAGAAGGGGCGATGG
CGGCTGTGCTGGGGTTGGATTTCGACACGGCGACGGATGTTGCCGCGCGCGCTGCACAAGGGCAGGTATGCCAGATCGCA
AATGAGAACGATCCGGCGCAGAACGTGGTGTCGGGGGAAAAGGGCGCCGTTGAACGCGCCATCGTGCTGGCCAAGGAGGC
AGGTGCGAAACGCGCGCTTATGCTGCCGGTGTCGGCACCGTTCCACTGTGCCTTGATGGCACCGGCGGCGAAAGAAATGG
CGCAGGCGCTGGAAGAGGTCGAGATGTCAGCGCCACAGGTGCCTTTGGTGGCGAATGTGCTGGGAACGGCTGTGGAGGAT
CCTGCCCGCATCAAGGAATTGCTGATTGATCAGGTGACAGGGCAGGTGCGCTGGAAAACCTCGGTCGAATGGATGGCCGC
GCAGGGCGTGACAGAGTTCTGGGAGATCGGCGCGGGCAAGGCCCTCAGCGGGATGATCCGGCGCATCGCAAAAGACAGCG
TGTCACGTGCGATTGGCACCCCCGAGGATATCAAAGCGGCAGTGAATGCCTGA

Upstream 100 bases:

>100_bases
ATGTGGCGCAGGCACTGTGCGCGCGGTGCGACTGGCCGTTGCTCTTGGGGTGCGGGCAGGCTAATCGGGAGGCAGTAAAG
AAAACCGAAGGGCAGATTTC

Downstream 100 bases:

>100_bases
AGGGAGAAGAATAGATGTTTGATCTGACAGGAAAGACGGCCCTGATCACCGGCGCCTCGGGCGGTATTGGCGCGGATATC
GCGCGCGCGCTTCATGGTGC

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MSIAFVFPGQGAQTVGMGRALAEAYPDAQAVFDEVDDALGEKLSALIWEGDIETLTLTQNAQPALMATSMAAIRALAAEG
VGMERLSFVAGHSLGEYSALAAAGTFSIADTARLLRTRGLAMQRAVPVGEGAMAAVLGLDFDTATDVAARAAQGQVCQIA
NENDPAQNVVSGEKGAVERAIVLAKEAGAKRALMLPVSAPFHCALMAPAAKEMAQALEEVEMSAPQVPLVANVLGTAVED
PARIKELLIDQVTGQVRWKTSVEWMAAQGVTEFWEIGAGKALSGMIRRIAKDSVSRAIGTPEDIKAAVNA

Sequences:

>Translated_310_residues
MSIAFVFPGQGAQTVGMGRALAEAYPDAQAVFDEVDDALGEKLSALIWEGDIETLTLTQNAQPALMATSMAAIRALAAEG
VGMERLSFVAGHSLGEYSALAAAGTFSIADTARLLRTRGLAMQRAVPVGEGAMAAVLGLDFDTATDVAARAAQGQVCQIA
NENDPAQNVVSGEKGAVERAIVLAKEAGAKRALMLPVSAPFHCALMAPAAKEMAQALEEVEMSAPQVPLVANVLGTAVED
PARIKELLIDQVTGQVRWKTSVEWMAAQGVTEFWEIGAGKALSGMIRRIAKDSVSRAIGTPEDIKAAVNA
>Mature_309_residues
SIAFVFPGQGAQTVGMGRALAEAYPDAQAVFDEVDDALGEKLSALIWEGDIETLTLTQNAQPALMATSMAAIRALAAEGV
GMERLSFVAGHSLGEYSALAAAGTFSIADTARLLRTRGLAMQRAVPVGEGAMAAVLGLDFDTATDVAARAAQGQVCQIAN
ENDPAQNVVSGEKGAVERAIVLAKEAGAKRALMLPVSAPFHCALMAPAAKEMAQALEEVEMSAPQVPLVANVLGTAVEDP
ARIKELLIDQVTGQVRWKTSVEWMAAQGVTEFWEIGAGKALSGMIRRIAKDSVSRAIGTPEDIKAAVNA

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=296, Percent_Identity=31.0810810810811, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI27477045, Length=107, Percent_Identity=38.3177570093458, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787334, Length=306, Percent_Identity=46.4052287581699, Blast_Score=231, Evalue=5e-62,
Organism=Caenorhabditis elegans, GI71984332, Length=294, Percent_Identity=28.9115646258503, Blast_Score=117, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI17550940, Length=295, Percent_Identity=28.4745762711864, Blast_Score=98, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24665753, Length=297, Percent_Identity=32.6599326599327, Blast_Score=120, Evalue=8e-28,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32259; Mature: 32128

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIAFVFPGQGAQTVGMGRALAEAYPDAQAVFDEVDDALGEKLSALIWEGDIETLTLTQN
CEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
AQPALMATSMAAIRALAAEGVGMERLSFVAGHSLGEYSALAAAGTFSIADTARLLRTRGL
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHCH
AMQRAVPVGEGAMAAVLGLDFDTATDVAARAAQGQVCQIANENDPAQNVVSGEKGAVERA
HHHHCCCCCCCHHHHHHCCCCCHHHHHHHHHCCCCEEEECCCCCCHHHHHCCCCCHHHHH
IVLAKEAGAKRALMLPVSAPFHCALMAPAAKEMAQALEEVEMSAPQVPLVANVLGTAVED
HHHHHHCCCCEEEEEECCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
PARIKELLIDQVTGQVRWKTSVEWMAAQGVTEFWEIGAGKALSGMIRRIAKDSVSRAIGT
HHHHHHHHHHHHCCCEEEECCHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
PEDIKAAVNA
HHHHHHHCCC
>Mature Secondary Structure 
SIAFVFPGQGAQTVGMGRALAEAYPDAQAVFDEVDDALGEKLSALIWEGDIETLTLTQN
EEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
AQPALMATSMAAIRALAAEGVGMERLSFVAGHSLGEYSALAAAGTFSIADTARLLRTRGL
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHCH
AMQRAVPVGEGAMAAVLGLDFDTATDVAARAAQGQVCQIANENDPAQNVVSGEKGAVERA
HHHHCCCCCCCHHHHHHCCCCCHHHHHHHHHCCCCEEEECCCCCCHHHHHCCCCCHHHHH
IVLAKEAGAKRALMLPVSAPFHCALMAPAAKEMAQALEEVEMSAPQVPLVANVLGTAVED
HHHHHHCCCCEEEEEECCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
PARIKELLIDQVTGQVRWKTSVEWMAAQGVTEFWEIGAGKALSGMIRRIAKDSVSRAIGT
HHHHHHHHHHHHCCCEEEECCHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
PEDIKAAVNA
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]